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FI831941A0 - Foerfarande foer framstaellning av n-(2-metoxi-etyl)-noroximorfon och dess syraadditionssalter - Google Patents

Foerfarande foer framstaellning av n-(2-metoxi-etyl)-noroximorfon och dess syraadditionssalter

Info

Publication number
FI831941A0
FI831941A0 FI831941A FI831941A FI831941A0 FI 831941 A0 FI831941 A0 FI 831941A0 FI 831941 A FI831941 A FI 831941A FI 831941 A FI831941 A FI 831941A FI 831941 A0 FI831941 A0 FI 831941A0
Authority
FI
Finland
Prior art keywords
noroximorphone
syringes
methoxy
ethyl
frequency refrigeration
Prior art date
Application number
FI831941A
Other languages
English (en)
Other versions
FI831941L (fi
FI78101B (fi
FI78101C (fi
Inventor
Herbert Merz
Adolf Langbein
Klaus Stockhaus
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of FI831941A0 publication Critical patent/FI831941A0/fi
Publication of FI831941L publication Critical patent/FI831941L/fi
Publication of FI78101B publication Critical patent/FI78101B/fi
Application granted granted Critical
Publication of FI78101C publication Critical patent/FI78101C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08Oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI831941A 1982-06-03 1983-05-31 Foerfarande foer framstaellning av farmakologiskt vaerdefulla n-(2-metoxietyl)-noroximorfoner. FI78101C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823220831 DE3220831A1 (de) 1982-06-03 1982-06-03 N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
DE3220831 1982-06-03

Publications (4)

Publication Number Publication Date
FI831941A0 true FI831941A0 (fi) 1983-05-31
FI831941L FI831941L (fi) 1983-12-04
FI78101B FI78101B (fi) 1989-02-28
FI78101C FI78101C (fi) 1989-06-12

Family

ID=6165151

Family Applications (1)

Application Number Title Priority Date Filing Date
FI831941A FI78101C (fi) 1982-06-03 1983-05-31 Foerfarande foer framstaellning av farmakologiskt vaerdefulla n-(2-metoxietyl)-noroximorfoner.

Country Status (27)

Country Link
US (1) US4473573A (fi)
EP (1) EP0096279B1 (fi)
JP (1) JPS591487A (fi)
KR (1) KR900006754B1 (fi)
AU (1) AU558319B2 (fi)
CA (1) CA1196633A (fi)
CS (1) CS236882B2 (fi)
CZ (1) CZ410691A3 (fi)
DD (1) DD209834A5 (fi)
DE (2) DE3220831A1 (fi)
DK (1) DK156068C (fi)
ES (1) ES522897A0 (fi)
FI (1) FI78101C (fi)
GB (1) GB2121041B (fi)
GR (1) GR78273B (fi)
HK (1) HK1389A (fi)
HU (1) HU185832B (fi)
IE (1) IE55232B1 (fi)
IL (1) IL68872A0 (fi)
NO (1) NO158579C (fi)
NZ (1) NZ204451A (fi)
PH (1) PH19518A (fi)
PL (1) PL139569B1 (fi)
PT (1) PT76805B (fi)
SG (1) SG58788G (fi)
SU (1) SU1195909A3 (fi)
ZA (1) ZA833981B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132159A1 (de) * 1991-09-27 1993-04-01 Boehringer Ingelheim Kg 14-hydroxy-n-(2-methoxyethyl)-7,8-dihydromorphin und -norisomorphin, verfahren zu deren herstellung und deren verwendung als arzneimittel
TR201908514T4 (tr) 2009-12-04 2019-07-22 Alkermes Pharma Ireland Ltd İlaç doz aşimi tedavi̇si̇ i̇çi̇n morfi̇nan türevleri̇
HRP20240109T1 (hr) 2010-08-23 2024-03-29 Alkermes Pharma Ireland Limited Postupci za liječenje povećanja tjelesne težine induciranog antipsihoticima
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
WO2014190271A2 (en) 2013-05-24 2014-11-27 Alkermes Pharma Ireland Limted Methods for treating depressive symptoms
JP2016519161A (ja) 2013-05-24 2016-06-30 アルカームス ファーマ アイルランド リミテッド モルファン及びモルフィナン類似物及び使用の方法
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332950A (en) * 1963-03-23 1967-07-25 Endo Lab 14-hydroxydihydronormorphinone derivatives
DE2538075A1 (de) * 1975-08-27 1977-03-17 Boehringer Sohn Ingelheim N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
AU558319B2 (en) 1987-01-29
PT76805B (de) 1986-04-09
KR900006754B1 (ko) 1990-09-20
GR78273B (fi) 1984-09-26
GB2121041B (en) 1985-09-11
DD209834A5 (de) 1984-05-23
DK250783A (da) 1983-12-04
GB8315292D0 (en) 1983-07-06
IL68872A0 (en) 1983-10-31
HK1389A (en) 1989-01-13
KR840005146A (ko) 1984-11-03
NO158579B (no) 1988-06-27
DE3220831A1 (de) 1983-12-08
NO831995L (no) 1983-12-05
DK250783D0 (da) 1983-06-02
PT76805A (de) 1983-07-01
FI831941L (fi) 1983-12-04
NZ204451A (en) 1986-07-11
HU185832B (en) 1985-04-28
SU1195909A3 (ru) 1985-11-30
DK156068C (da) 1989-11-06
CA1196633A (en) 1985-11-12
JPH0373552B2 (fi) 1991-11-22
ES8403487A1 (es) 1984-03-16
ES522897A0 (es) 1984-03-16
SG58788G (en) 1989-03-10
PH19518A (en) 1986-05-14
DK156068B (da) 1989-06-19
US4473573A (en) 1984-09-25
AU1531483A (en) 1983-12-08
JPS591487A (ja) 1984-01-06
ZA833981B (en) 1985-01-30
CS236882B2 (en) 1985-05-15
EP0096279A1 (de) 1983-12-21
GB2121041A (en) 1983-12-14
IE55232B1 (en) 1990-07-04
PL242312A1 (en) 1985-04-09
FI78101B (fi) 1989-02-28
CZ410691A3 (en) 1993-02-17
IE831299L (en) 1983-12-03
PL139569B1 (en) 1987-02-28
DE3361165D1 (en) 1985-12-12
EP0096279B1 (de) 1985-11-06
NO158579C (no) 1988-10-05
FI78101C (fi) 1989-06-12

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BOEHRINGER INGELHEIM KG