FI780882A - Morfinderivat - Google Patents
MorfinderivatInfo
- Publication number
- FI780882A FI780882A FI780882A FI780882A FI780882A FI 780882 A FI780882 A FI 780882A FI 780882 A FI780882 A FI 780882A FI 780882 A FI780882 A FI 780882A FI 780882 A FI780882 A FI 780882A
- Authority
- FI
- Finland
- Prior art keywords
- morfinderivat
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1232577 | 1977-03-23 | ||
| GB12325/77A GB1593191A (en) | 1977-03-23 | 1977-03-23 | Derivatives of morphine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI780882A true FI780882A (fi) | 1978-09-24 |
| FI68236B FI68236B (fi) | 1985-04-30 |
| FI68236C FI68236C (fi) | 1985-08-12 |
Family
ID=10002423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI780882A FI68236C (fi) | 1977-03-23 | 1978-03-21 | Foerfarande foer framstaellning av nya farmakologiskt aktiva morfinderivat |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4241066A (fi) |
| JP (1) | JPS53119899A (fi) |
| AT (1) | AT361139B (fi) |
| AU (1) | AU519643B2 (fi) |
| BE (1) | BE865183A (fi) |
| CA (1) | CA1089456A (fi) |
| CH (1) | CH629809A5 (fi) |
| CS (1) | CS200542B2 (fi) |
| DD (1) | DD133950A5 (fi) |
| DE (1) | DE2812580A1 (fi) |
| DK (1) | DK149858C (fi) |
| ES (1) | ES468173A1 (fi) |
| FI (1) | FI68236C (fi) |
| FR (1) | FR2384774A1 (fi) |
| GB (1) | GB1593191A (fi) |
| IE (1) | IE46443B1 (fi) |
| IT (1) | IT1105176B (fi) |
| LU (1) | LU79294A1 (fi) |
| NL (1) | NL7803083A (fi) |
| NZ (1) | NZ186692A (fi) |
| PL (1) | PL114723B1 (fi) |
| SE (1) | SE436131B (fi) |
| SU (1) | SU921467A3 (fi) |
| ZA (1) | ZA781527B (fi) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4362870A (en) * | 1980-01-16 | 1982-12-07 | Regents Of The University Of Minnesota | Selective opioid receptor alkylating agents |
| US4401672A (en) * | 1981-10-13 | 1983-08-30 | Regents Of The University Of Minnesota | Non-addictive narcotic antitussive preparation |
| EP0103636B1 (en) * | 1982-03-16 | 1990-09-12 | Rockefeller University | Use of opium antagonists for the manufacture of medicaments for controlling gastrointestinal dysmotility |
| GB8711558D0 (en) * | 1987-05-15 | 1987-06-17 | Reckitt & Colmann Prod Ltd | Derivative of codeine |
| CA2105072C (en) * | 1992-01-23 | 1998-07-28 | Hiroshi Nagase | Morphinan derivative and its pharmaceutical applications |
| IT1269826B (it) * | 1994-05-24 | 1997-04-15 | Paolo Minoia | Uso di antagonisti degli oppiacei e di sali di calcio per la preparazione di medicamenti per il trattamento di forme patologiche endorfino-mediate |
| CN104383542B (zh) | 2003-04-08 | 2017-09-26 | 普罗热尼奇制药公司 | 包含甲基纳曲酮的药物配方 |
| US20060063792A1 (en) * | 2004-09-17 | 2006-03-23 | Adolor Corporation | Substituted morphinans and methods of their use |
| AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
| JP2008546688A (ja) | 2005-06-16 | 2008-12-25 | マリンクロッド・インコーポレイテッド | １−ハロ−テバインまたは類似体を介する１４−ヒドロキシルオピエート類への合成経路 |
| CA2646313C (en) * | 2006-04-21 | 2014-05-20 | Nektar Therapeutics Al, Corporation | Stereoselective reduction of a morphinone |
| EP2565195B1 (en) | 2007-03-29 | 2015-05-06 | Wyeth LLC | Peripheral opioid receptor and antagonists and uses thereof |
| CA2865661C (en) | 2007-03-29 | 2016-05-17 | Progenics Pharmaceuticals, Inc. | Peripheral opioid receptor antagonists and uses thereof |
| EP2134718A2 (en) | 2007-03-29 | 2009-12-23 | Progenics Pharmaceuticals, Inc. | Crystal forms of (r)-n-methylnaltrexone bromide and uses thereof |
| WO2009099411A1 (en) | 2008-02-06 | 2009-08-13 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
| EP2344509B1 (en) | 2008-09-30 | 2015-11-11 | Mallinckrodt LLC | Processes for the production of buprenorphine with reduced impurity formation |
| US8293906B2 (en) | 2008-09-30 | 2012-10-23 | Mallinckrodt Llc | Processes for the alkylation of norbuprenorphine with reduced impurity formation |
| CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
| EP3077398B1 (en) | 2013-12-05 | 2020-03-11 | The University of Bath | Novel opioid compounds and their uses |
| CN110330500B (zh) * | 2019-07-12 | 2021-11-23 | 宜昌人福药业有限责任公司 | 一种6β-羟基-7,8-二氢-吗啡衍生物的立体选择性合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3322771A (en) * | 1967-05-30 | Intermediates for preparing thebaine derivatives | ||
| US3332950A (en) * | 1963-03-23 | 1967-07-25 | Endo Lab | 14-hydroxydihydronormorphinone derivatives |
| IL26896A (en) * | 1966-01-19 | 1970-11-30 | Endo Lab | 14 - Hydroxynormorphinins and 14 - Hydroxynormorphinones |
| BE788478A (fr) * | 1971-09-08 | 1973-03-06 | Bristol Myers Co | Procede de preparation de composes analgesiques |
| US4017497A (en) * | 1975-11-18 | 1977-04-12 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinan derivatives |
| US4089855A (en) * | 1976-04-23 | 1978-05-16 | Cornell Research Foundation, Inc. | Process for the stereoselective reduction of 6- and 8-keto morphine and morphinan derivatives with formamidinesulfinic acid and compounds obtained thereby |
-
1977
- 1977-03-23 GB GB12325/77A patent/GB1593191A/en not_active Expired
-
1978
- 1978-03-14 IE IE515/78A patent/IE46443B1/en unknown
- 1978-03-14 NZ NZ186692A patent/NZ186692A/xx unknown
- 1978-03-15 US US05/886,833 patent/US4241066A/en not_active Expired - Lifetime
- 1978-03-15 ZA ZA00781527A patent/ZA781527B/xx unknown
- 1978-03-21 SU SU782595556A patent/SU921467A3/ru active
- 1978-03-21 FI FI780882A patent/FI68236C/fi not_active IP Right Cessation
- 1978-03-21 AU AU34357/78A patent/AU519643B2/en not_active Expired
- 1978-03-22 DE DE19782812580 patent/DE2812580A1/de not_active Ceased
- 1978-03-22 NL NL7803083A patent/NL7803083A/xx not_active Application Discontinuation
- 1978-03-22 JP JP3354678A patent/JPS53119899A/ja active Granted
- 1978-03-22 IT IT48544/78A patent/IT1105176B/it active
- 1978-03-22 DK DK130078A patent/DK149858C/da not_active IP Right Cessation
- 1978-03-22 ES ES468173A patent/ES468173A1/es not_active Expired
- 1978-03-22 PL PL1978205498A patent/PL114723B1/pl unknown
- 1978-03-22 FR FR7808404A patent/FR2384774A1/fr active Granted
- 1978-03-22 CS CS781846A patent/CS200542B2/cs unknown
- 1978-03-22 CA CA299,532A patent/CA1089456A/en not_active Expired
- 1978-03-22 CH CH316078A patent/CH629809A5/fr not_active IP Right Cessation
- 1978-03-22 LU LU79294A patent/LU79294A1/xx unknown
- 1978-03-22 BE BE186174A patent/BE865183A/xx not_active IP Right Cessation
- 1978-03-22 SE SE7803328A patent/SE436131B/sv not_active IP Right Cessation
- 1978-03-22 DD DD78204349A patent/DD133950A5/xx unknown
- 1978-03-22 AT AT204278A patent/AT361139B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL114723B1 (en) | 1981-02-28 |
| PL205498A1 (pl) | 1979-04-09 |
| IT1105176B (it) | 1985-10-28 |
| GB1593191A (en) | 1981-07-15 |
| IE46443B1 (en) | 1983-06-15 |
| AT361139B (de) | 1981-02-25 |
| JPS53119899A (en) | 1978-10-19 |
| IE780515L (en) | 1978-09-23 |
| FI68236B (fi) | 1985-04-30 |
| FI68236C (fi) | 1985-08-12 |
| CA1089456A (en) | 1980-11-11 |
| SE436131B (sv) | 1984-11-12 |
| CH629809A5 (fr) | 1982-05-14 |
| ES468173A1 (es) | 1979-09-16 |
| DD133950A5 (de) | 1979-01-31 |
| NZ186692A (en) | 1980-02-21 |
| DK149858C (da) | 1987-06-29 |
| SE7803328L (sv) | 1978-09-24 |
| SU921467A3 (ru) | 1982-04-15 |
| FR2384774A1 (fr) | 1978-10-20 |
| AU519643B2 (en) | 1981-12-17 |
| CS200542B2 (en) | 1980-09-15 |
| FR2384774B1 (fi) | 1981-10-16 |
| NL7803083A (nl) | 1978-09-26 |
| DK149858B (da) | 1986-10-13 |
| IT7848544A0 (it) | 1978-03-22 |
| DK130078A (da) | 1978-09-24 |
| ATA204278A (de) | 1980-07-15 |
| LU79294A1 (fr) | 1979-10-29 |
| BE865183A (fr) | 1978-09-22 |
| ZA781527B (en) | 1979-04-25 |
| JPH0112755B2 (fi) | 1989-03-02 |
| US4241066A (en) | 1980-12-23 |
| AU3435778A (en) | 1979-09-27 |
| DE2812580A1 (de) | 1978-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: RECKITT & COLAMN PRODUKTS LIMITED |