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FI64640C - Foerfarande foer framstaellning av en kombinations-dna-molekylsom innehaoller en foer insulin kodande nukleotidsekvens hocsom kan anvaendas vid framstaellning av en insulin produ rcende mikroorganism - Google Patents

Foerfarande foer framstaellning av en kombinations-dna-molekylsom innehaoller en foer insulin kodande nukleotidsekvens hocsom kan anvaendas vid framstaellning av en insulin produ rcende mikroorganism Download PDF

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Publication number
FI64640C
FI64640C FI781675A FI781675A FI64640C FI 64640 C FI64640 C FI 64640C FI 781675 A FI781675 A FI 781675A FI 781675 A FI781675 A FI 781675A FI 64640 C FI64640 C FI 64640C
Authority
FI
Finland
Prior art keywords
dna
insulin
cdna
mrna
sequence
Prior art date
Application number
FI781675A
Other languages
English (en)
Finnish (fi)
Other versions
FI781675A (fi
FI64640B (fi
Inventor
William J Rutter
Howard Michael Goodman
Axel Ullrich
John Mitchell Chirgwin
Raymond Louis Pictet
Peter Horst Seeburg
John Shine
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05897710 external-priority patent/US4363877B1/en
Priority claimed from US05/898,887 external-priority patent/US4264731A/en
Application filed by Univ California filed Critical Univ California
Publication of FI781675A publication Critical patent/FI781675A/fi
Priority to FI810687A priority Critical patent/FI65446C/fi
Priority to FI810689A priority patent/FI75185C/fi
Priority to FI810692A priority patent/FI810692L/fi
Priority to FI810686A priority patent/FI64953C/fi
Priority to FI810688A priority patent/FI65447C/fi
Priority to FI810690A priority patent/FI74732C/fi
Priority to FI810691A priority patent/FI810691L/fi
Publication of FI64640B publication Critical patent/FI64640B/fi
Publication of FI64640C publication Critical patent/FI64640C/fi
Application granted granted Critical

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57518—Placental lactogen; Chorionic somatomammotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
FI781675A 1977-05-27 1978-05-26 Foerfarande foer framstaellning av en kombinations-dna-molekylsom innehaoller en foer insulin kodande nukleotidsekvens hocsom kan anvaendas vid framstaellning av en insulin produ rcende mikroorganism FI64640C (fi)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FI810691A FI810691L (fi) 1977-05-27 1981-03-05 Mikroorganism innehaollande insulin
FI810687A FI65446C (fi) 1977-05-27 1981-03-05 Foerfarande foer framstaellning av en bakterie som innehaolleren foer insulin kodande nukleotidsekvens
FI810690A FI74732C (fi) 1978-04-19 1981-03-05 Dna-oeverfoeringsvektor, vilken innehaoller en nukleotidsekvens som kodar foer tillvaexthormon.
FI810689A FI75185C (fi) 1977-05-27 1981-03-05 Dna-oeverfoeringsvektor, vilken innehaoller en foer insulin kodande nukleotidsekvens.
FI810692A FI810692L (fi) 1978-04-19 1981-03-05 Mikroorganism innehaollande tillvaexthormon
FI810686A FI64953C (fi) 1977-05-27 1981-03-05 Foerfarande foer framstaellning av en rekombinant-dna-molekyl som innehaoller en foer tillvaexthormon kodande nukleotidsekvens och som kan anvaendas vid framstaellning av en tillvaexthormon producerande mikroorganism
FI810688A FI65447C (fi) 1977-05-27 1981-03-05 Foerfarande foer framstaellning av en bakterie som innehaolleren foer tillvaexthormon kodande nukleotidsekvens

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US80134377A 1977-05-27 1977-05-27
US80134377 1977-05-27
US80502377A 1977-06-09 1977-06-09
US80502377 1977-06-09
US89770978A 1978-04-19 1978-04-19
US89770978 1978-04-19
US89771078 1978-04-19
US05897710 US4363877B1 (en) 1977-09-23 1978-04-19 Recombinant dna transfer vectors
US89888778 1978-04-21
US05/898,887 US4264731A (en) 1977-05-27 1978-04-21 DNA Joining method
US89900378A 1978-04-26 1978-04-26
US89900278A 1978-04-26 1978-04-26
US89900378 1978-04-26
US89900278 1978-04-26

Publications (3)

Publication Number Publication Date
FI781675A FI781675A (fi) 1978-11-28
FI64640B FI64640B (fi) 1983-08-31
FI64640C true FI64640C (fi) 1983-12-12

Family

ID=27569921

Family Applications (1)

Application Number Title Priority Date Filing Date
FI781675A FI64640C (fi) 1977-05-27 1978-05-26 Foerfarande foer framstaellning av en kombinations-dna-molekylsom innehaoller en foer insulin kodande nukleotidsekvens hocsom kan anvaendas vid framstaellning av en insulin produ rcende mikroorganism

Country Status (21)

Country Link
JP (1) JPH0659218B2 (nl)
AR (1) AR225404A1 (nl)
AU (1) AU521903B2 (nl)
BE (1) BE867424A (nl)
BG (1) BG40319A3 (nl)
CH (1) CH642680A5 (nl)
DD (1) DD145927A5 (nl)
DE (2) DE2858357C2 (nl)
DK (2) DK233278A (nl)
FI (1) FI64640C (nl)
FR (1) FR2392033B1 (nl)
GB (1) GB1565190A (nl)
GR (1) GR73552B (nl)
IL (1) IL54790A (nl)
IT (1) IT1094934B (nl)
LU (1) LU79714A1 (nl)
NL (1) NL7805591A (nl)
NZ (1) NZ187300A (nl)
PL (1) PL140200B1 (nl)
PT (1) PT68082B (nl)
SE (4) SE451461B (nl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA782933B (en) * 1977-09-23 1979-05-30 Univ California Purification of nucleotide sequences suitable for expression in bacteria
BR7807290A (pt) * 1977-11-08 1979-06-12 Genentech Inc Plasmideo,processo para producao de um polipeptido especifico veiculo clonal,cultura bacteriana transformante,processo para produzir uma substancia imunogenica processo para preparar um gene estrutural,e polidesoxirribonucleotido de faixa dupla
GR71912B (nl) * 1978-08-11 1983-08-16 Univ California
US6270955B1 (en) 1978-12-22 2001-08-07 Biogen, Inc. Pharmaceutical compositions and methods for producing antibodies to hepatitis b virus and kits and methods for detecting antibodies to hepatitis b virus
JPS55150883A (en) * 1979-05-11 1980-11-25 Nakano Vinegar Co Ltd Method of storing "mozuku"
ZA802992B (en) * 1979-06-01 1981-10-28 Univ California Human pre-growth hormone
FR2458584A1 (fr) * 1979-06-08 1981-01-02 Pasteur Institut Vecteurs pour le transfert et l'expression de materiel genetique dans une cellule eucaryote et procede pour la production d'une proteine determinee dans des cellules eucaryotes
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
GR70279B (nl) * 1979-09-12 1982-09-03 Univ California
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
DE3001928A1 (de) * 1980-01-19 1981-08-06 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
IL61982A (en) * 1980-02-15 1984-01-31 Cpc International Inc Genetically engineered microorganisms for massive production of amyloytic enzymes and process for preparing same using the corresponding recombinant dnas containing amylase coding genes
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
CA1202581A (en) * 1980-03-27 1986-04-01 Saran A. Narang Adaptor molecules for dna and their application to synthesis of gene-derived products
US4370417A (en) * 1980-04-03 1983-01-25 Abbott Laboratories Recombinant deoxyribonucleic acid which codes for plasminogen activator
US4338397A (en) 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
EP0054331B1 (en) * 1980-12-12 1992-06-03 Unilever N.V. Structural genes encoding the various allelic and maturation forms of preprothaumatin and mutations thereof, recombinant cloning vehicles comprising said structural genes and expression thereof in transformed microbial host cells
ATE22327T1 (de) * 1980-12-12 1986-10-15 Unilever Nv Dna-sequenzen fuer verschiedene allele formen des reifen thaumatins, diese sequenzen enthaltende rekombinante plasmide, verfahren zur herstellung dieser plasmide, diese rekombinante plasmide enthaltende bakterielle kulturen und verfahren zur herstellung von reifen thaumatin.
US4748233A (en) * 1982-03-23 1988-05-31 Bristol-Myers Company Alpha-interferon Gx-1
US4695543A (en) * 1982-03-23 1987-09-22 Bristol-Myers Company Alpha Interferon GX-1
EP0103395A3 (en) * 1982-08-17 1985-05-22 Biogen N.V. Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield
US5474980A (en) * 1984-10-04 1995-12-12 Monsanto Company Prolonged release of biologically active somatotropins
US5411951A (en) * 1984-10-04 1995-05-02 Monsanto Company Prolonged release of biologically active somatotropin
DK257988D0 (da) * 1988-05-11 1988-05-11 Novo Industri As Nye peptider
DE4034702A1 (de) * 1990-10-31 1992-05-07 Siemens Ag Verfahren und vorrichtung zur pruefung der aktiven werkzeuge von gesenkbiegemaschinen, insbesondere von biegestempeln

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment

Also Published As

Publication number Publication date
SE8305327D0 (sv) 1983-09-29
BE867424A (fr) 1978-09-18
SE8305328L (sv) 1983-09-29
FI781675A (fi) 1978-11-28
PT68082A (en) 1978-06-01
IL54790A (en) 1983-07-31
DK233278A (da) 1978-11-28
DK791D0 (da) 1991-01-04
JPS5449387A (en) 1979-04-18
FR2392033A1 (fr) 1978-12-22
SE8305329L (sv) 1983-09-29
BG40319A3 (en) 1986-11-14
AU521903B2 (en) 1982-05-06
GR73552B (nl) 1984-03-14
IT1094934B (it) 1985-08-10
DE2858357C2 (nl) 1990-03-15
PL207176A1 (pl) 1979-03-26
FI64640B (fi) 1983-08-31
DE2822568C2 (nl) 1989-08-31
PT68082B (en) 1980-02-20
DD145927A5 (de) 1981-01-14
NZ187300A (en) 1982-08-17
SE8305327L (sv) 1983-09-29
SE455794B (sv) 1988-08-08
DE2822568A1 (de) 1978-12-14
IT7823930A0 (it) 1978-05-29
IL54790A0 (en) 1978-07-31
SE8305329D0 (sv) 1983-09-29
SE7806086L (sv) 1978-11-28
AU3648878A (en) 1979-11-29
GB1565190A (en) 1980-04-16
DK791A (da) 1991-01-04
FR2392033B1 (fr) 1985-09-13
SE451461B (sv) 1987-10-12
LU79714A1 (fr) 1978-11-06
SE8305328D0 (sv) 1983-09-29
NL7805591A (nl) 1978-11-29
AR225404A1 (es) 1982-03-31
JPH0659218B2 (ja) 1994-08-10
PL140200B1 (en) 1987-04-30
CH642680A5 (en) 1984-04-30

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