FI103203B1 - Uusi menetelmä 1-fenyyli-imidatsolin-2,5-dionin johdannaisten valmistamiseksi - Google Patents

Uusi menetelmä 1-fenyyli-imidatsolin-2,5-dionin johdannaisten valmistamiseksi

Info

Publication number: FI103203B1
Authority: FI; Finland
Prior art keywords: phenyl; preparation; new process; formula; image
Prior art date: 1989-12-22

Application number

FI906366A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI906366L (fi

FI103203B (fi

FI906366A0 (fi

Inventor

Patrick Seuron

Daniel Varraillon

Original Assignee

Hoechst Marion Roussel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-22

Filing date

1990-12-21

Publication date

1999-05-14

1990-12-21 Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc

1990-12-21 Publication of FI906366A0 publication Critical patent/FI906366A0/fi

1991-06-23 Publication of FI906366L publication Critical patent/FI906366L/fi

1999-05-14 Application granted granted Critical

1999-05-14 Publication of FI103203B publication Critical patent/FI103203B/fi

1999-05-14 Publication of FI103203B1 publication Critical patent/FI103203B1/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)
Reinforced Plastic Materials (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Photoreceptors In Electrophotography (AREA)
Compositions Of Macromolecular Compounds (AREA)

FI906366A 1989-12-22 1990-12-21 Uusi menetelmä 1-fenyyli-imidatsolin-2,5-dionin johdannaisten valmistamiseksi FI103203B1 (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8917046A FR2656302B1 (fr)	1989-12-22	1989-12-22	Nouveau procede de preparation de l'anandron et derives de l'anandron.

Publications (4)

Publication Number	Publication Date
FI906366A0 FI906366A0 (fi)	1990-12-21
FI906366L FI906366L (fi)	1991-06-23
FI103203B FI103203B (fi)	1999-05-14
FI103203B1 true FI103203B1 (fi)	1999-05-14

Family

ID=9388859

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI906366A FI103203B1 (fi)	1989-12-22	1990-12-21	Uusi menetelmä 1-fenyyli-imidatsolin-2,5-dionin johdannaisten valmistamiseksi

Country Status (24)

Country	Link
US (1)	US5166358A (de)
EP (1)	EP0436426B1 (de)
JP (1)	JP2836041B2 (de)
KR (1)	KR0173307B1 (de)
CN (1)	CN1048011C (de)
AT (1)	ATE107289T1 (de)
AU (1)	AU628699B2 (de)
CA (1)	CA2032988C (de)
CZ (1)	CZ281655B6 (de)
DE (1)	DE69009964T2 (de)
DK (1)	DK0436426T3 (de)
ES (1)	ES2055382T3 (de)
FI (1)	FI103203B1 (de)
FR (1)	FR2656302B1 (de)
HU (1)	HU207301B (de)
IE (1)	IE65510B1 (de)
IL (1)	IL96696A (de)
NZ (1)	NZ236621A (de)
PL (1)	PL164694B1 (de)
PT (1)	PT96313B (de)
RU (1)	RU1836356C (de)
SK (1)	SK278447B6 (de)
UA (1)	UA27220C2 (de)
ZA (1)	ZA909648B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2693461B1 (fr) *	1992-07-08	1994-09-02	Roussel Uclaf	Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
US5411981A (en) *	1991-01-09	1995-05-02	Roussel Uclaf	Phenylimidazolidines having antiandrogenic activity
FR2694290B1 (fr) *	1992-07-08	1994-09-02	Roussel Uclaf	Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
US5656651A (en) *	1995-06-16	1997-08-12	Biophysica Inc.	Androgenic directed compositions
FR2741346B1 (fr) *	1995-11-16	1997-12-19	Roussel Uclaf	Nouveau procede de preparation de derives phenylimidazolidine
FR2741342B1 (fr) *	1995-11-22	1998-02-06	Roussel Uclaf	Nouvelles phenylimidazolidines fluorees ou hydroxylees, procede, intermediaires de preparation, application comme medicaments, nouvelle utilisation et compositions pharmaceutiques
JPH1072446A (ja) *	1996-06-24	1998-03-17	Sumitomo Chem Co Ltd	１−置換−ヒダントイン類の製造法
US7001911B2 (en)	2000-06-28	2006-02-21	Bristol-Myers Squibb Company	Fused cyclic modulators of nuclear hormone receptor function
US20040077605A1 (en)	2001-06-20	2004-04-22	Salvati Mark E.	Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
IL152719A0 (en) *	2000-06-28	2003-06-24	Bristol Myers Squibb Co	Selective androgen receptor modulators and methods for their identification
EP1854798A3 (de)	2000-09-19	2007-11-28	Bristol-Myers Squibb Company	Kondensierte heterozyklische Succinimid-Verbindungen und Analoga daraus, Modulatoren der nuklearen Hormonrezeptorfunktion
US6953679B2 (en)	2000-09-19	2005-10-11	Bristol-Myers Squibb Company	Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
US20040087548A1 (en)	2001-02-27	2004-05-06	Salvati Mark E.	Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
PL206962B1 (pl)	2001-12-19	2010-10-29	Bristol Myers Squibb Co	Związek heterocykliczny o budowie skondensowanej
JP2007514442A (ja) *	2003-12-19	2007-06-07	ザリージェンツオブザユニバーシティオブカリフォルニア	前立腺癌治療を評価するための方法および物質
AU2005232526B2 (en) *	2004-02-24	2011-06-23	The Regents Of The University Of California	Methods and materials for assessing prostate cancer therapies and compounds
US7709517B2 (en) *	2005-05-13	2010-05-04	The Regents Of The University Of California	Diarylhydantoin compounds
LT3100727T (lt)	2006-03-27	2018-12-10	The Regents Of The University Of California	Androgeno receptoriaus moduliatorius, skirtas prostatos vėžio ir su androgeno receptoriumi susijusių ligų gydymui
CN101460467B (zh) *	2006-03-29	2012-09-19	加利福尼亚大学董事会	二芳基硫代乙内酰脲化合物
EP2620432A3 (de)	2007-10-26	2013-12-18	The Regents Of the University of California	Diarylhydantoinverbindungen
KR101819199B1 (ko)	2010-02-16	2018-01-16	아라곤 파마슈티컬스, 인코포레이티드	안드로겐 수용체 조절제 및 이의 용도
MY180834A (en)	2012-09-26	2020-12-10	Aragon Pharmaceuticals Inc	Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
JOP20200097A1 (ar)	2013-01-15	2017-06-16	Aragon Pharmaceuticals Inc	معدل مستقبل أندروجين واستخداماته
TWI726969B (zh)	2016-01-11	2021-05-11	比利時商健生藥品公司	用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
JP7201694B2 (ja)	2017-10-16	2023-01-10	アラゴンファーマシューティカルズ，インコーポレイテッド	非転移性去勢抵抗性前立腺癌の治療のための抗アンドロゲン剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH166004A (de) *	1934-06-06	1933-12-15	Chem Fab Vormals Sandoz	Verfahren zur Darstellung eines Derivates des 5,5-Phenyläthylhydantoins.
US2490813A (en) *	1944-11-29	1949-12-13	Standard Oil Co	Continuous process for making aryl amines
US2759002A (en) *	1954-03-24	1956-08-14	Abbott Lab	3-benzyl hydantoin and process
US3134663A (en) *	1957-07-23	1964-05-26	Geigy Chem Corp	Herbicidal composition and method employing hydantoins
US3914311A (en) *	1973-06-15	1975-10-21	Du Pont	Preparation of aromatic secondary and tertiary amines using a nickel complex catalyst
DE2414613A1 (de) *	1974-03-26	1975-10-16	Bayer Ag	1-aryl-5-alkyliden-2,4-dioxo-imidazolidine
FR2329276A1 (fr) *	1975-10-29	1977-05-27	Roussel Uclaf	Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant
CA1138334A (en) *	1977-10-28	1982-12-28	Karl Bernauer	Pharmaceutical preparations containing certain urea derivatives
GB1598166A (en) *	1978-05-23	1981-09-16	Lilly Industries Ltd	3,5-disubstituted hydantoin derivatives
US4764625A (en) *	1980-12-12	1988-08-16	Xerox Corporation	Process for preparing arylamines
DE3382406D1 (de) *	1982-04-08	1991-10-17	Shell Int Research	Neue hydantoine, ihre herstellung und verwendung.

1989
- 1989-12-22 FR FR8917046A patent/FR2656302B1/fr not_active Expired - Fee Related
1990
- 1990-11-16 IE IE414290A patent/IE65510B1/en not_active IP Right Cessation
- 1990-11-30 ZA ZA909648A patent/ZA909648B/xx unknown
- 1990-12-10 JP JP2407176A patent/JP2836041B2/ja not_active Expired - Lifetime
- 1990-12-17 IL IL9669690A patent/IL96696A/en not_active IP Right Cessation
- 1990-12-18 US US07/629,490 patent/US5166358A/en not_active Expired - Lifetime
- 1990-12-20 AU AU68265/90A patent/AU628699B2/en not_active Expired
- 1990-12-20 PL PL90288365A patent/PL164694B1/pl unknown
- 1990-12-21 PT PT96313A patent/PT96313B/pt not_active IP Right Cessation
- 1990-12-21 CA CA002032988A patent/CA2032988C/fr not_active Expired - Lifetime
- 1990-12-21 SK SK6567-90A patent/SK278447B6/sk not_active IP Right Cessation
- 1990-12-21 RU SU904894040A patent/RU1836356C/ru active
- 1990-12-21 ES ES90403725T patent/ES2055382T3/es not_active Expired - Lifetime
- 1990-12-21 HU HU908416A patent/HU207301B/hu unknown
- 1990-12-21 NZ NZ236621A patent/NZ236621A/en unknown
- 1990-12-21 KR KR1019900021357A patent/KR0173307B1/ko not_active Expired - Lifetime
- 1990-12-21 DE DE69009964T patent/DE69009964T2/de not_active Expired - Lifetime
- 1990-12-21 CZ CS906567A patent/CZ281655B6/cs not_active IP Right Cessation
- 1990-12-21 DK DK90403725.6T patent/DK0436426T3/da active
- 1990-12-21 EP EP90403725A patent/EP0436426B1/de not_active Expired - Lifetime
- 1990-12-21 UA UA4894040A patent/UA27220C2/uk unknown
- 1990-12-21 AT AT90403725T patent/ATE107289T1/de not_active IP Right Cessation
- 1990-12-21 FI FI906366A patent/FI103203B1/fi active IP Right Grant
- 1990-12-22 CN CN90110071A patent/CN1048011C/zh not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IE65510B1 (en)	1995-11-01
CN1048011C (zh)	2000-01-05
AU6826590A (en)	1991-06-27
RU1836356C (ru)	1993-08-23
US5166358A (en)	1992-11-24
IE904142A1 (en)	1991-07-03
IL96696A (en)	1995-08-31
KR910011799A (ko)	1991-08-07
AU628699B2 (en)	1992-09-17
SK656790A3 (en)	1997-06-04
KR0173307B1 (ko)	1999-02-01
PL288365A1 (en)	1991-09-09
HU207301B (en)	1993-03-29
JPH04103573A (ja)	1992-04-06
PT96313B (pt)	1998-06-30
DE69009964D1 (de)	1994-07-21
FI906366L (fi)	1991-06-23
EP0436426B1 (de)	1994-06-15
CN1052666A (zh)	1991-07-03
DK0436426T3 (da)	1994-07-04
EP0436426A1 (de)	1991-07-10
CA2032988C (fr)	2003-04-29
ATE107289T1 (de)	1994-07-15
CZ656790A3 (en)	1996-08-14
JP2836041B2 (ja)	1998-12-14
HU908416D0 (en)	1991-07-29
CZ281655B6 (cs)	1996-12-11
ZA909648B (en)	1992-02-26
FI103203B (fi)	1999-05-14
ES2055382T3 (es)	1994-08-16
FR2656302A1 (fr)	1991-06-28
NZ236621A (en)	1992-04-28
CA2032988A1 (fr)	1991-06-23
SK278447B6 (en)	1997-06-04
UA27220C2 (uk)	2000-08-15
PT96313A (pt)	1991-09-30
PL164694B1 (pl)	1994-09-30
IL96696A0 (en)	1991-09-16
DE69009964T2 (de)	1994-10-13
FR2656302B1 (fr)	1992-05-07
FI906366A0 (fi)	1990-12-21

Publication	Publication Date	Title
FI103203B1 (fi)	1999-05-14	Uusi menetelmä 1-fenyyli-imidatsolin-2,5-dionin johdannaisten valmistamiseksi
FI924522A0 (fi)	1992-10-07	Foerfarande foer framstaellning av substituerade n-(aryl)-1,2,4-triazolopyrimidin-2-sulfonamider
AU534361B2 (en)	1984-01-26	Processes
ATE3284T1 (de)	1983-05-15	Derivate der 9-cis-6,6'-diapo-psi,psicarotindis[ure, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen.
SE8001556L (sv)	1980-09-03	Tetrahydrobensotiazolylimidazolidinoner
ATE38665T1 (de)	1988-12-15	Verfahren zur herstellung von 5-perfluoralkyl-5,6-dihydrouracyl-derivaten und verwendbare zwischenprodukte.
ATE18195T1 (de)	1986-03-15	Dioxybenzoletherderivate, diese enthaltende arzneimittel, verfahren zu ihrer herstellung und ihre verwendung.
DE3560027D1 (en)	1987-01-15	Process for the preparation of o,o'-dithiobenzamides
ATE52082T1 (de)	1990-05-15	Chinolinderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende zubereitungen.
DE3168178D1 (en)	1985-02-21	2-(n-aryl-n-1,2,3-thiadiazolyl-carbonyl)-aminobutyrolactones, their preparation, fungicides containing them and their use as fungicides
GB2011897A (en)	1979-07-18	Process for Preparing Anthranylaldehyde Derivatives
FR2376139A1 (fr)	1978-07-28	Nouveaux derives d'isoquinoleine-acetamide utiles comme medicaments
JPS5217467A (en)	1977-02-09	Process for preparation of 5-alkoxy-2- oxazoleacetate or propionate de rivatives
FR2401927A1 (fr)	1979-03-30	Derives de thiazine utiles comme medicaments
ES483300A1 (es)	1980-09-01	Un procedimiento para la preparacion de derivados de benzo- diacepina
TH19594A (th)	1996-07-16	ไตรอาโซลิลเมทธิลเฟนนิลแนพธีริโดนที่ถูกแทนที่
PT75181A (fr)	1982-08-01	Procede de preparation de derives phenethylesde thiazole et de compositions pharmaceutiques les contenant

Legal Events

Date	Code	Title	Description
1990-12-21	FG	Patent granted	Owner name: HOECHST MARION ROUSSEL
1998-10-15	GB	Transfer or assigment of application	Owner name: HOECHST MARION ROUSSEL
2004-08-31	FG	Patent granted	Owner name: AVENTIS PHARMA S.A.