ES8608496A1 - Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol - Google Patents
Procedimiento para la obtencion de nuevos compuestos de aralquiltriazolInfo
- Publication number
- ES8608496A1 ES8608496A1 ES543624A ES543624A ES8608496A1 ES 8608496 A1 ES8608496 A1 ES 8608496A1 ES 543624 A ES543624 A ES 543624A ES 543624 A ES543624 A ES 543624A ES 8608496 A1 ES8608496 A1 ES 8608496A1
- Authority
- ES
- Spain
- Prior art keywords
- lower alkyl
- substituted
- lower alkylene
- thia
- aza
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002947 alkylene group Chemical group 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000002252 acyl group Chemical group 0.000 abstract 4
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000001118 alkylidene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000002082 anti-convulsion Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 1-FENILO-ALQUILO INFERIOR-1H-1,2,3-TRIAZOL Y DE SUS SALES, DE FORMULA (I), EN LA QUE ALK REPRESENTA ALQUILIDENO INFERIOR; Y PH, R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA PH-ALD-Z, CON UN DERIVADO DE 1H-1,2,3-TRIAZOL, O UNA DE SUS SALES, DE FORMULA (II), EN LAS QUE Z REPRESENTA HIDROXI ESTERIFICADO, CAPAZ DE REACCION, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE EFECTUA EN UN DISOLVENTE INERTE, EN PRESENCIA DE UN AGENTE DE CONDENSACION BASICO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA EPILEPSIA.43
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH752682 | 1982-12-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES543624A0 ES543624A0 (es) | 1986-06-16 |
| ES8608496A1 true ES8608496A1 (es) | 1986-06-16 |
Family
ID=4326531
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528267A Granted ES528267A0 (es) | 1982-12-23 | 1983-12-21 | Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol |
| ES543624A Expired ES8608496A1 (es) | 1982-12-23 | 1985-05-29 | Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol |
| ES543623A Expired ES8608495A1 (es) | 1982-12-23 | 1985-05-29 | Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528267A Granted ES528267A0 (es) | 1982-12-23 | 1983-12-21 | Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES543623A Expired ES8608495A1 (es) | 1982-12-23 | 1985-05-29 | Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0114347A3 (es) |
| JP (1) | JPS59118775A (es) |
| AU (1) | AU566730B2 (es) |
| DD (1) | DD216456A5 (es) |
| DK (1) | DK591983A (es) |
| ES (3) | ES528267A0 (es) |
| FI (1) | FI834666A7 (es) |
| GR (1) | GR79452B (es) |
| HU (1) | HU191388B (es) |
| IL (1) | IL70508A (es) |
| NO (1) | NO834770L (es) |
| NZ (1) | NZ206696A (es) |
| PT (1) | PT77867B (es) |
| ZA (1) | ZA839478B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0151528B1 (en) * | 1984-02-02 | 1990-07-04 | Merck & Co. Inc. | 5-(amino or substituted amino)-1,2,3-triazoles |
| PH22568A (en) * | 1985-04-18 | 1988-10-17 | Ciba Geigy Ag | Fluorinated benzyl triazoles and pharmaceutical compositions containing the same |
| US5498620A (en) * | 1989-05-19 | 1996-03-12 | The United States Of America As Represented By The Department Of Health And Human Services | Signal transduction inhibitor 1,2,3-triazolo compounds |
| US5880129A (en) * | 1989-05-19 | 1999-03-09 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of inhibiting invasion and metastasis of malignant solid tumors |
| US5359078A (en) * | 1989-05-19 | 1994-10-25 | The United States Of America As Represented By The Department Of Health And Human Services | Signal transduction inhibitor compounds |
| WO1997040025A1 (en) * | 1996-04-19 | 1997-10-30 | Novo Nordisk A/S | Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles |
| TW526195B (en) | 1997-06-10 | 2003-04-01 | Novartis Ag | Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use |
| GB0507298D0 (en) | 2005-04-11 | 2005-05-18 | Novartis Ag | Organic compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL50699A0 (en) * | 1975-10-28 | 1976-12-31 | Ici America Inc | Triazole derivatives |
| CH632291A5 (de) * | 1978-01-10 | 1982-09-30 | Sandoz Ag | Organische azoverbindungen. |
| CH639376A5 (en) * | 1979-02-14 | 1983-11-15 | Sandoz Ag | Process for preparing disperse dyes of the triazolylazo class |
-
1983
- 1983-12-19 FI FI834666A patent/FI834666A7/fi not_active Application Discontinuation
- 1983-12-20 EP EP83112847A patent/EP0114347A3/de not_active Withdrawn
- 1983-12-21 GR GR73317A patent/GR79452B/el unknown
- 1983-12-21 IL IL70508A patent/IL70508A/xx unknown
- 1983-12-21 DD DD83258352A patent/DD216456A5/de unknown
- 1983-12-21 PT PT77867A patent/PT77867B/pt unknown
- 1983-12-21 ES ES528267A patent/ES528267A0/es active Granted
- 1983-12-21 ZA ZA839478A patent/ZA839478B/xx unknown
- 1983-12-22 AU AU22807/83A patent/AU566730B2/en not_active Ceased
- 1983-12-22 HU HU834423A patent/HU191388B/hu unknown
- 1983-12-22 DK DK591983A patent/DK591983A/da not_active Application Discontinuation
- 1983-12-22 JP JP58241096A patent/JPS59118775A/ja active Pending
- 1983-12-22 NZ NZ206696A patent/NZ206696A/en unknown
- 1983-12-22 NO NO834770A patent/NO834770L/no unknown
-
1985
- 1985-05-29 ES ES543624A patent/ES8608496A1/es not_active Expired
- 1985-05-29 ES ES543623A patent/ES8608495A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU2280783A (en) | 1984-06-28 |
| DK591983D0 (da) | 1983-12-22 |
| DD216456A5 (de) | 1984-12-12 |
| NZ206696A (en) | 1986-02-21 |
| ES543623A0 (es) | 1986-06-16 |
| HU191388B (en) | 1987-02-27 |
| FI834666A0 (fi) | 1983-12-19 |
| NO834770L (no) | 1984-06-25 |
| ES543624A0 (es) | 1986-06-16 |
| EP0114347A3 (de) | 1986-01-29 |
| PT77867B (en) | 1986-05-08 |
| PT77867A (en) | 1984-01-01 |
| ES8608495A1 (es) | 1986-06-16 |
| ES8601930A1 (es) | 1985-11-16 |
| FI834666A7 (fi) | 1984-06-24 |
| GR79452B (es) | 1984-10-30 |
| DK591983A (da) | 1984-06-24 |
| IL70508A (en) | 1988-03-31 |
| ZA839478B (en) | 1984-08-29 |
| AU566730B2 (en) | 1987-10-29 |
| IL70508A0 (en) | 1984-03-30 |
| ES528267A0 (es) | 1985-11-16 |
| JPS59118775A (ja) | 1984-07-09 |
| EP0114347A2 (de) | 1984-08-01 |
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