ES8608495A1 - Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol - Google Patents
Procedimiento para la obtencion de nuevos compuestos de aralquiltriazolInfo
- Publication number
- ES8608495A1 ES8608495A1 ES543623A ES543623A ES8608495A1 ES 8608495 A1 ES8608495 A1 ES 8608495A1 ES 543623 A ES543623 A ES 543623A ES 543623 A ES543623 A ES 543623A ES 8608495 A1 ES8608495 A1 ES 8608495A1
- Authority
- ES
- Spain
- Prior art keywords
- lower alkyl
- substituted
- lower alkylene
- thia
- aza
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002947 alkylene group Chemical group 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000002252 acyl group Chemical group 0.000 abstract 4
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000001118 alkylidene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000002082 anti-convulsion Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE 1-FENILO-ALQUILO INFERIOR-1H-1,2,3-TRIAZOL Y DE SUS SALES, DE FORMULA (I), EN LA QUE ALK REPRESENTA ALQUILIDENO INFERIOR; Y PH, R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA TRANSFORMACION DE YA O YB EN CARBAMILO, EN UN COMPUESTO DE FORMULA (II), EN LA QUE Y4 REPRESENTA R2 O YA, Y5 ES R1 O YB, DONDE YA E YB SON RESTOS TRANSFORMABLES EN CARBAMILO, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA TRANSFORMACION SE LLEVA A CABO MEDIANTE SOLVOLISIS A TEMPERATURA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIEPILEPTICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH752682 | 1982-12-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES543623A0 ES543623A0 (es) | 1986-06-16 |
| ES8608495A1 true ES8608495A1 (es) | 1986-06-16 |
Family
ID=4326531
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528267A Granted ES528267A0 (es) | 1982-12-23 | 1983-12-21 | Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol |
| ES543624A Expired ES8608496A1 (es) | 1982-12-23 | 1985-05-29 | Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol |
| ES543623A Expired ES8608495A1 (es) | 1982-12-23 | 1985-05-29 | Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528267A Granted ES528267A0 (es) | 1982-12-23 | 1983-12-21 | Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol |
| ES543624A Expired ES8608496A1 (es) | 1982-12-23 | 1985-05-29 | Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0114347A3 (es) |
| JP (1) | JPS59118775A (es) |
| AU (1) | AU566730B2 (es) |
| DD (1) | DD216456A5 (es) |
| DK (1) | DK591983A (es) |
| ES (3) | ES528267A0 (es) |
| FI (1) | FI834666A7 (es) |
| GR (1) | GR79452B (es) |
| HU (1) | HU191388B (es) |
| IL (1) | IL70508A (es) |
| NO (1) | NO834770L (es) |
| NZ (1) | NZ206696A (es) |
| PT (1) | PT77867B (es) |
| ZA (1) | ZA839478B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0151528B1 (en) * | 1984-02-02 | 1990-07-04 | Merck & Co. Inc. | 5-(amino or substituted amino)-1,2,3-triazoles |
| PH22568A (en) * | 1985-04-18 | 1988-10-17 | Ciba Geigy Ag | Fluorinated benzyl triazoles and pharmaceutical compositions containing the same |
| US5498620A (en) * | 1989-05-19 | 1996-03-12 | The United States Of America As Represented By The Department Of Health And Human Services | Signal transduction inhibitor 1,2,3-triazolo compounds |
| US5880129A (en) * | 1989-05-19 | 1999-03-09 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of inhibiting invasion and metastasis of malignant solid tumors |
| US5359078A (en) * | 1989-05-19 | 1994-10-25 | The United States Of America As Represented By The Department Of Health And Human Services | Signal transduction inhibitor compounds |
| WO1997040025A1 (en) * | 1996-04-19 | 1997-10-30 | Novo Nordisk A/S | Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles |
| TW526195B (en) | 1997-06-10 | 2003-04-01 | Novartis Ag | Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use |
| GB0507298D0 (en) | 2005-04-11 | 2005-05-18 | Novartis Ag | Organic compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL50699A0 (en) * | 1975-10-28 | 1976-12-31 | Ici America Inc | Triazole derivatives |
| CH632291A5 (de) * | 1978-01-10 | 1982-09-30 | Sandoz Ag | Organische azoverbindungen. |
| CH639376A5 (en) * | 1979-02-14 | 1983-11-15 | Sandoz Ag | Process for preparing disperse dyes of the triazolylazo class |
-
1983
- 1983-12-19 FI FI834666A patent/FI834666A7/fi not_active Application Discontinuation
- 1983-12-20 EP EP83112847A patent/EP0114347A3/de not_active Withdrawn
- 1983-12-21 GR GR73317A patent/GR79452B/el unknown
- 1983-12-21 IL IL70508A patent/IL70508A/xx unknown
- 1983-12-21 DD DD83258352A patent/DD216456A5/de unknown
- 1983-12-21 PT PT77867A patent/PT77867B/pt unknown
- 1983-12-21 ES ES528267A patent/ES528267A0/es active Granted
- 1983-12-21 ZA ZA839478A patent/ZA839478B/xx unknown
- 1983-12-22 AU AU22807/83A patent/AU566730B2/en not_active Ceased
- 1983-12-22 HU HU834423A patent/HU191388B/hu unknown
- 1983-12-22 DK DK591983A patent/DK591983A/da not_active Application Discontinuation
- 1983-12-22 JP JP58241096A patent/JPS59118775A/ja active Pending
- 1983-12-22 NZ NZ206696A patent/NZ206696A/en unknown
- 1983-12-22 NO NO834770A patent/NO834770L/no unknown
-
1985
- 1985-05-29 ES ES543624A patent/ES8608496A1/es not_active Expired
- 1985-05-29 ES ES543623A patent/ES8608495A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU2280783A (en) | 1984-06-28 |
| DK591983D0 (da) | 1983-12-22 |
| DD216456A5 (de) | 1984-12-12 |
| NZ206696A (en) | 1986-02-21 |
| ES543623A0 (es) | 1986-06-16 |
| HU191388B (en) | 1987-02-27 |
| FI834666A0 (fi) | 1983-12-19 |
| NO834770L (no) | 1984-06-25 |
| ES543624A0 (es) | 1986-06-16 |
| EP0114347A3 (de) | 1986-01-29 |
| PT77867B (en) | 1986-05-08 |
| PT77867A (en) | 1984-01-01 |
| ES8601930A1 (es) | 1985-11-16 |
| FI834666A7 (fi) | 1984-06-24 |
| GR79452B (es) | 1984-10-30 |
| DK591983A (da) | 1984-06-24 |
| IL70508A (en) | 1988-03-31 |
| ZA839478B (en) | 1984-08-29 |
| AU566730B2 (en) | 1987-10-29 |
| IL70508A0 (en) | 1984-03-30 |
| ES8608496A1 (es) | 1986-06-16 |
| ES528267A0 (es) | 1985-11-16 |
| JPS59118775A (ja) | 1984-07-09 |
| EP0114347A2 (de) | 1984-08-01 |
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