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ES8406480A1 - Un compuesto - Google Patents

Un compuesto

Info

Publication number
ES8406480A1
ES8406480A1 ES522679A ES522679A ES8406480A1 ES 8406480 A1 ES8406480 A1 ES 8406480A1 ES 522679 A ES522679 A ES 522679A ES 522679 A ES522679 A ES 522679A ES 8406480 A1 ES8406480 A1 ES 8406480A1
Authority
ES
Spain
Prior art keywords
theophylline
substituted
salts
substituted theophylline
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES522679A
Other languages
English (en)
Other versions
ES522679A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of ES8406480A1 publication Critical patent/ES8406480A1/es
Publication of ES522679A0 publication Critical patent/ES522679A0/es
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE TEOFILINA, DE FORMULA GENERAL (I).COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE HACE REACCIONAR EL HIDRATO DE 5,6-DIAMINO-1,3-DIMETIL-URACILO CON ACIDO CIANOCETICO, PARA OBTENER 5-CIANOACETAMIDO-6-AMINO- 1,3-DIMETILURACILO; SEGUNDA, EL PRODUCTO OBTENIDO SE HACE REACCIONAR CON HIDROXIDO DE SODIO, PARA OBTENER UN COMPUESTO DE FORMULA (II); Y POR ULTIMO, EL COMPUESTO DE FORMULA (II) SE HACE REACCIONAR CON UN INHIBIDOR ALQUILADO DE FORMULA (III).DE APLICACION COMO REACTIVOS EN IN INMUNOENSAYO INHIBIDOR DE ENZIMA IRREVERSIBLE CONTEOFILINA.
ES522679A 1982-05-24 1983-05-24 Un compuesto Granted ES522679A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/380,981 US4451652A (en) 1982-05-24 1982-05-24 Substituted theophylline salts

Publications (2)

Publication Number Publication Date
ES8406480A1 true ES8406480A1 (es) 1984-08-01
ES522679A0 ES522679A0 (es) 1984-08-01

Family

ID=23503202

Family Applications (1)

Application Number Title Priority Date Filing Date
ES522679A Granted ES522679A0 (es) 1982-05-24 1983-05-24 Un compuesto

Country Status (9)

Country Link
US (1) US4451652A (es)
JP (1) JPS58213791A (es)
BE (1) BE896802A (es)
CA (1) CA1215051A (es)
DE (1) DE3318809C2 (es)
ES (1) ES522679A0 (es)
FR (1) FR2527211A1 (es)
GB (1) GB2121803B (es)
IT (1) IT1164234B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543412A (en) * 1983-11-04 1985-09-24 Abbott Laboratories Phenobarbital enzyme inhibitors
ES2298146T3 (es) * 1999-06-25 2008-05-16 Roche Diagnostics Operations, Inc. Inmunoensayo de inhibicion de enzimas.
US6962209B2 (en) * 2001-10-17 2005-11-08 Turfco Manufacturing Inc. Simple, durable and easy-to-use earthworking machine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273866A (en) * 1979-02-05 1981-06-16 Abbott Laboratories Ligand analog-irreversible enzyme inhibitor conjugates and methods for use

Also Published As

Publication number Publication date
GB8311847D0 (en) 1983-06-02
IT1164234B (it) 1987-04-08
FR2527211A1 (fr) 1983-11-25
BE896802A (fr) 1983-11-21
CA1215051A (en) 1986-12-09
JPH0134228B2 (es) 1989-07-18
IT8321257A0 (it) 1983-05-24
GB2121803B (en) 1985-10-23
ES522679A0 (es) 1984-08-01
JPS58213791A (ja) 1983-12-12
US4451652A (en) 1984-05-29
DE3318809A1 (de) 1983-11-24
IT8321257A1 (it) 1984-11-24
FR2527211B1 (es) 1985-05-17
GB2121803A (en) 1984-01-04
DE3318809C2 (de) 1985-01-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001