ES8205221A1 - Procedimiento para la preparacion de una sulfonamida. - Google Patents
Procedimiento para la preparacion de una sulfonamida.Info
- Publication number
- ES8205221A1 ES8205221A1 ES499984A ES499984A ES8205221A1 ES 8205221 A1 ES8205221 A1 ES 8205221A1 ES 499984 A ES499984 A ES 499984A ES 499984 A ES499984 A ES 499984A ES 8205221 A1 ES8205221 A1 ES 8205221A1
- Authority
- ES
- Spain
- Prior art keywords
- octyl
- dimethyl
- phenothiazine
- preparation
- azabicyclo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 2-bromopheny l Chemical class 0.000 abstract 2
- KHBQMWCZKVMBLN-UHFFFAOYSA-N Benzenesulfonamide Chemical compound NS(=O)(=O)C1=CC=CC=C1 KHBQMWCZKVMBLN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 229950000688 phenothiazine Drugs 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 239000002731 stomach secretion inhibitor Substances 0.000 abstract 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE UNA SULFONAMIDA DE FORMULA (I). CONSISTE EN LA REACCION DE CONDENSACION DE 1-AZA-3-BICICLO-(2,2,2) OCTANONA CON N,N-DIMETIL-3-AMINO-4-((2-BROMOFENIL)TIO)BENCENOSULFONAMIDA EN UN DISOLVENTE INERTE, EN PRESENCIA DE UN AGENTE DE DESHIDRATACION Y A LA TEMPERATURA DE EBULLICION DEL MEDIO, SEGUIDA DE LA REDUCCION DE LA IMINA FORMADA CON UN BOROHIDRURO DE METAL ALCALINO EN ETANOL ENTRE 0 A 40 GRADOS CENTIGRADOS, Y CICLACION DEL COMPUESTO FORMADO ENN PRESENCIA DE UN AMIDURO DE METAL ALCALINO A UNA TEMPERATURA ENTRE 20 GRADOS CENTIGRADOS Y LA DE EBULLICION DEL DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO INHIBIDORES DE LA SECRECION GASTRICA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8100442A FR2497806A1 (fr) | 1981-01-13 | 1981-01-13 | Nouveau procede de preparation du n,n-dimethyl (aza-1 bicyclo (2,2,2) octyl-3)-10 10h-phenothiazinesulfonamide-2 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES499984A0 ES499984A0 (es) | 1982-06-01 |
| ES8205221A1 true ES8205221A1 (es) | 1982-06-01 |
Family
ID=9254052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES499984A Expired ES8205221A1 (es) | 1981-01-13 | 1981-03-02 | Procedimiento para la preparacion de una sulfonamida. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4482711A (es) |
| EP (1) | EP0056201B1 (es) |
| JP (1) | JPS57123179A (es) |
| AR (1) | AR226096A1 (es) |
| AT (1) | ATE14733T1 (es) |
| AU (1) | AU537401B2 (es) |
| CA (1) | CA1152067A (es) |
| DE (1) | DE3171646D1 (es) |
| DK (1) | DK109381A (es) |
| ES (1) | ES8205221A1 (es) |
| FI (1) | FI810591L (es) |
| FR (1) | FR2497806A1 (es) |
| GR (1) | GR77287B (es) |
| HU (1) | HU182307B (es) |
| IL (1) | IL62304A (es) |
| MA (1) | MA19089A1 (es) |
| NO (1) | NO810721L (es) |
| PT (1) | PT72667B (es) |
| ZA (1) | ZA811440B (es) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909521A (en) * | 1959-10-20 | Phenthiazine derivatives | ||
| CA611405A (en) * | 1960-12-27 | M. Jacob Robert | Phenthiazine derivatives and their preparation | |
| DE1047202B (de) * | 1955-11-23 | 1958-12-24 | Rhone Poulenc Sa | Verfahren zur Herstellung des 10-[2',4'-Bis(dimethylamino)-butyl-(1')]-phenthiazins |
| NL295220A (es) * | 1962-07-19 | |||
| US3534053A (en) * | 1967-05-24 | 1970-10-13 | American Home Prod | Quinuclidine derivatives |
| GB1250534A (es) * | 1969-03-03 | 1971-10-20 | ||
| US3987042A (en) * | 1969-03-03 | 1976-10-19 | Claude Gueremy | Phenothiazine derivative |
| US3563995A (en) * | 1969-04-17 | 1971-02-16 | Ian Wellings | Alkyl esters of 1-azabicyclo(2.2.2)oct-2-ene-3-(4 - chloro-3-sulfamoylanilino)-2-carboxylic acid |
| FR2318638A2 (fr) * | 1975-07-25 | 1977-02-18 | Sogeras | Nouveaux derives de la phenothiazine et procede pour leur preparation |
-
1981
- 1981-01-13 FR FR8100442A patent/FR2497806A1/fr active Granted
- 1981-02-20 EP EP81400261A patent/EP0056201B1/fr not_active Expired
- 1981-02-20 DE DE8181400261T patent/DE3171646D1/de not_active Expired
- 1981-02-20 AT AT81400261T patent/ATE14733T1/de not_active IP Right Cessation
- 1981-02-25 FI FI810591A patent/FI810591L/fi not_active Application Discontinuation
- 1981-03-02 ES ES499984A patent/ES8205221A1/es not_active Expired
- 1981-03-03 NO NO810721A patent/NO810721L/no unknown
- 1981-03-04 ZA ZA00811440A patent/ZA811440B/xx unknown
- 1981-03-05 MA MA19293A patent/MA19089A1/fr unknown
- 1981-03-05 IL IL62304A patent/IL62304A/xx unknown
- 1981-03-06 CA CA000372504A patent/CA1152067A/fr not_active Expired
- 1981-03-10 DK DK109381A patent/DK109381A/da unknown
- 1981-03-11 AR AR284583A patent/AR226096A1/es active
- 1981-03-13 AU AU68361/81A patent/AU537401B2/en not_active Ceased
- 1981-03-16 PT PT72667A patent/PT72667B/pt unknown
- 1981-03-17 HU HU81675A patent/HU182307B/hu unknown
- 1981-03-23 JP JP56042245A patent/JPS57123179A/ja active Pending
- 1981-03-27 GR GR64514A patent/GR77287B/el unknown
-
1982
- 1982-08-02 US US06/404,116 patent/US4482711A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA1152067A (fr) | 1983-08-16 |
| PT72667B (fr) | 1982-06-15 |
| IL62304A (en) | 1984-06-29 |
| PT72667A (fr) | 1981-04-01 |
| FI810591L (fi) | 1982-07-14 |
| MA19089A1 (fr) | 1981-10-01 |
| GR77287B (es) | 1984-09-11 |
| HU182307B (en) | 1983-12-28 |
| ES499984A0 (es) | 1982-06-01 |
| AU6836181A (en) | 1982-07-22 |
| FR2497806A1 (fr) | 1982-07-16 |
| JPS57123179A (en) | 1982-07-31 |
| IL62304A0 (en) | 1981-05-20 |
| DK109381A (da) | 1982-07-14 |
| NO810721L (no) | 1982-07-14 |
| ATE14733T1 (de) | 1985-08-15 |
| ZA811440B (en) | 1982-03-31 |
| DE3171646D1 (en) | 1985-09-12 |
| AU537401B2 (en) | 1984-06-21 |
| AR226096A1 (es) | 1982-05-31 |
| US4482711A (en) | 1984-11-13 |
| EP0056201A1 (fr) | 1982-07-21 |
| EP0056201B1 (en) | 1985-08-07 |
| FR2497806B1 (es) | 1983-06-10 |
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