ES468353A1 - Procedimiento para preparar acidos 15-deoxi-16-hidroxi-sus- tituido-prostanoicos opticamente activosÿ - Google Patents

Procedimiento para preparar acidos 15-deoxi-16-hidroxi-sus- tituido-prostanoicos opticamente activosÿ

Info

Publication number: ES468353A1
Authority: ES; Spain
Prior art keywords: alkyl; sch2; alkanoyloxy; antiinflammatories; agents
Prior art date: 1977-03-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES468353A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wyeth Holdings LLC

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-03-30

Filing date

1978-03-30

Publication date

1979-10-01

1977-03-30 Priority claimed from US05/782,858 external-priority patent/US4131737A/en

1978-03-30 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1979-10-01 Publication of ES468353A1 publication Critical patent/ES468353A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
- C07C45/305—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/02—Lithium compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Materials Engineering (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ES468353A 1977-03-30 1978-03-30 Procedimiento para preparar acidos 15-deoxi-16-hidroxi-sus- tituido-prostanoicos opticamente activosÿ Expired ES468353A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/782,858 US4131737A (en)	1976-07-19	1977-03-30	15-Deoxy-16-hydroxy-16-substituted-3-thia-prostanoic acids

Publications (1)

Publication Number	Publication Date
ES468353A1 true ES468353A1 (es)	1979-10-01

Family

ID=25127398

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES468353A Expired ES468353A1 (es)	1977-03-30	1978-03-30	Procedimiento para preparar acidos 15-deoxi-16-hidroxi-sus- tituido-prostanoicos opticamente activosÿ
ES481198A Expired ES481198A1 (es)	1977-03-30	1979-06-01	Procedimiento para preparar acidos 15-deoxi-16-hidroxi-16- sustituido-prostanoicos opticamente activos.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES481198A Expired ES481198A1 (es)	1977-03-30	1979-06-01	Procedimiento para preparar acidos 15-deoxi-16-hidroxi-16- sustituido-prostanoicos opticamente activos.

Country Status (9)

Country	Link
JP (1)	JPS5439047A (fr)
AU (1)	AU3437478A (fr)
BE (1)	BE865428R (fr)
DE (1)	DE2813342A1 (fr)
DK (1)	DK137778A (fr)
ES (2)	ES468353A1 (fr)
FR (1)	FR2385696A2 (fr)
NL (1)	NL7803418A (fr)
SE (1)	SE7803619L (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU529836B2 (en) *	1977-12-05	1983-06-23	American Cyanamid Company	Prostaglandin analog
JPH0424232Y2 (fr) *	1987-09-14	1992-06-08
FR2621376B1 (fr) *	1987-10-01	1989-12-22	Pont A Mousson	Garniture d'etancheite pour joints verrouilles telescopiques
FR2655705B1 (fr) *	1989-12-11	1992-05-29	Pont A Mousson	Garniture d'etancheite composite pour assemblage verrouille de tuyaux a bout male et emboitement.
CA2147461A1 (fr) *	1992-10-21	1994-04-28	Takehiro Amano	Analogues de la prostaglandine e1
US5618959A (en) *	1995-03-10	1997-04-08	Vivus Incorporated	Process for preparing prostaglandin E1, E2 and analogs thereof using furylcopper reagents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3965143A (en) *	1974-03-26	1976-06-22	G. D. Searle & Co.	16-Oxygenated prostanoic acid derivatives
AU529836B2 (en) *	1977-12-05	1983-06-23	American Cyanamid Company	Prostaglandin analog

1978
- 1978-03-21 AU AU34374/78A patent/AU3437478A/en active Pending
- 1978-03-28 DE DE2813342A patent/DE2813342A1/de not_active Withdrawn
- 1978-03-29 BE BE186360A patent/BE865428R/fr not_active IP Right Cessation
- 1978-03-29 DK DK137778A patent/DK137778A/da not_active Application Discontinuation
- 1978-03-30 FR FR7809306A patent/FR2385696A2/fr active Pending
- 1978-03-30 JP JP3617378A patent/JPS5439047A/ja active Pending
- 1978-03-30 NL NL7803418A patent/NL7803418A/xx not_active Application Discontinuation
- 1978-03-30 SE SE7803619A patent/SE7803619L/xx unknown
- 1978-03-30 ES ES468353A patent/ES468353A1/es not_active Expired
1979
- 1979-06-01 ES ES481198A patent/ES481198A1/es not_active Expired

Also Published As

Publication number	Publication date
BE865428R (fr)	1978-09-29
JPS5439047A (en)	1979-03-24
SE7803619L (sv)	1978-11-17
AU3437478A (en)	1979-09-27
NL7803418A (nl)	1978-10-03
ES481198A1 (es)	1980-09-01
DK137778A (da)	1978-10-01
FR2385696A2 (fr)	1978-10-27
DE2813342A1 (de)	1978-10-05

Publication	Publication Date	Title
ES482156A1 (es)	1980-08-16	Un procedimiento para la preparacion de nuevos derivados de-fenetanolamina.
PT73336A (en)	1981-08-01	Process for preparing carbamates of 1-(3,5-dihidroxiphenil)-2-butil terc.-amino)-ethanol with bronchial-spasmolitic activity and pharmaceutical compositions containing them
DK0415456T3 (da)	1996-07-29	Xanthinforbindelser
NO923081L (no)	1992-08-05	Neurobeskyttende 3-piperidino-4-hydroksykromanderivater og analoger derav
ES468353A1 (es)	1979-10-01	Procedimiento para preparar acidos 15-deoxi-16-hidroxi-sus- tituido-prostanoicos opticamente activosÿ
AU532435B2 (en)	1983-09-29	Dental compositions
ES8306474A1 (es)	1983-06-01	Derivados de encefalina.
ATE38028T1 (de)	1988-11-15	Cycloaliphatische heilmittelzusammensetzungen.
ES8502977A1 (es)	1985-02-01	Un metodo de preparar profarmacos de pilocarpina
HUT37145A (en)	1985-11-28	Process for the production of new indole derivatives and of therapeutic preparations containing these derivatives
NZ332687A (en)	2000-05-26	use of 1-methyl-carbapenem derivatives as anti-helicobacter pylori agents
IE890092L (en)	1989-07-15	Process for preparing hydroxyalkylating agents, the agents so obtained, and their use
FR2698789B1 (fr)	1995-03-03	Utilisation de l'idazoxan et ses dérivés pour la préparation d'un médicament destiné au traitement de la maladie de Parkinson et de son évolution.
ES478568A1 (es)	1979-05-16	Un procedimiento de preparacion de (1r.5s)-6,6-dimetil-4(r)--(s)-ciano-(3'-fenoxifenil)-metoxi-3-oxa-biciclo (3-1-0)- hexan-2-ona.
ATE25257T1 (de)	1987-02-15	3-(2-(azabicyclo)ethyl)1,2,3,4-tetrahydro-5h(1)benzopyran(3,4-c)pyridin-5-one, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung.
ES8307247A1 (es)	1983-06-16	"procedimiento para preparar nuevos derivados de 20,21-dinoreburnamenina".
FR2392004A1 (en)	1978-12-22	3-Thia-13-trans-prostenoic acid derivs. - useful as selective and long lasting hypotensives, antisecretories, antiulcer agents, contraceptives, CNS regulators, abortifacients, etc.
DE69108326D1 (en)	1995-04-27	15-deoxyprostaglandinderivat.
IT1207238B (it)	1989-05-17	Composizioni copolimeriche idrofile, morbide e permeabili all'ossigeno.
IT1126818B (it)	1986-05-21	Composti ipotensivi e vasodilatatori a base di prostaglandine per somministrazione topica o per iniezione
TW427978B (en)	2001-04-01	Tetrahydroisoquinoline derivatives
ES8801835A1 (es)	1988-02-16	Procedimiento para la obtencion de compuestos de 2-heterociclil-6-hidroxi-alquilo inferior-2-penem
ES498702A1 (es)	1981-11-01	Procedimiento para la obtencion de esteres de acido in- dan-4-il-n-alquilcarbamico
ES485392A1 (es)	1980-10-01	Un procedimiento para la preparacion de derivados de amino- alcoholes.
NL7903227A (en)	1980-10-28	Hypotensive prostaglandin=E derivs. - are 9-oxo-11-alpha, 16-di:hydroxy-15-deoxy-16-vinyl or cyclopropyl-prostenoic and prostadienoic acid ester(s)