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ES2225112T3 - Procedimiento de purificacion de acido lactico a escala industrial. - Google Patents

Procedimiento de purificacion de acido lactico a escala industrial.

Info

Publication number
ES2225112T3
ES2225112T3 ES00914368T ES00914368T ES2225112T3 ES 2225112 T3 ES2225112 T3 ES 2225112T3 ES 00914368 T ES00914368 T ES 00914368T ES 00914368 T ES00914368 T ES 00914368T ES 2225112 T3 ES2225112 T3 ES 2225112T3
Authority
ES
Spain
Prior art keywords
lactic acid
acid solution
industrial scale
concentrated
processing purification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00914368T
Other languages
English (en)
Inventor
Jan Van Breugel
Jan Van Krieken
Baro Agusti Cerda
Lancis Jose Maria Vidal
Vila Margarita Camprubi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purac Biochem BV
Original Assignee
Purac Biochem BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purac Biochem BV filed Critical Purac Biochem BV
Application granted granted Critical
Publication of ES2225112T3 publication Critical patent/ES2225112T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • C07C51/44—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Método de purificación de ácido láctico a escala industrial, que comprende las etapas siguientes: (a) destilación a presión reducida de una solución concentrada de ácido láctico con un contenido total de ácido de por lo menos el 95% en peso y un contenido de ácido láctico monomérico de por lo menos el 80% en peso, basado en la solución concentrada de ácido láctico, siendo la proporción de enantiómeros de ácido láctico en la solución concentrada de ácido láctico diferente de 1, con el fin de formar un concentrado de ácido láctico, y (b) cristalización del concentrado de ácido láctico para formar un ácido láctico puro, en el que la cristalización se lleva a cabo mediante: (i) enfriamiento directo del concentrado de ácido láctico en uno o más cristalizadores de fundido (ii) dilución del concentrado de ácido láctico con agua y cristalización en uno o más cristalizadores por enfriamiento y/o cristalizadores por evaporación, y/o (iii) cristalización en uno o más cristalizadores adiabáticos.
ES00914368T 1999-03-22 2000-03-21 Procedimiento de purificacion de acido lactico a escala industrial. Expired - Lifetime ES2225112T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL1011624 1999-03-22

Publications (1)

Publication Number Publication Date
ES2225112T3 true ES2225112T3 (es) 2005-03-16

Family

ID=19768882

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00914368T Expired - Lifetime ES2225112T3 (es) 1999-03-22 2000-03-21 Procedimiento de purificacion de acido lactico a escala industrial.

Country Status (11)

Country Link
US (1) US6630603B1 (es)
EP (1) EP1163200B9 (es)
JP (3) JP2002540090A (es)
CN (1) CN1285559C (es)
AT (1) ATE276994T1 (es)
AU (1) AU3575700A (es)
BR (1) BRPI0009229B8 (es)
DE (1) DE60014047T2 (es)
DK (1) DK1163200T3 (es)
ES (1) ES2225112T3 (es)
WO (1) WO2000056693A1 (es)

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US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
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BE1018561A3 (fr) 2008-12-24 2011-03-01 Galactic Sa Procede de purification de l'acide lactique par cristallisation.
SG172400A1 (en) 2008-12-26 2011-08-29 Toray Industries Method for producing lactic acid and method for producing polylactic acid
JP5359348B2 (ja) * 2009-02-18 2013-12-04 東レ株式会社 高純度乳酸の製造方法
ES2436509T3 (es) * 2009-07-16 2014-01-02 Purac Biochem Bv Composición líquida de ácido láctico y método para su preparación
DE102009029651A1 (de) 2009-09-22 2011-03-24 Evonik Röhm Gmbh Verfahren zur Herstellung freier Carbonsäuren
JP2013505727A (ja) 2009-09-27 2013-02-21 オーピーエックス バイオテクノロジーズ， インコーポレイテッド ３−ヒドロキシプロピオン酸および他の生成物を生成するための方法
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
CN103140482B (zh) * 2010-08-28 2017-03-29 诺沃梅尔公司 由环氧乙烷制备的丁二酸酐
FI20115496A (fi) * 2011-05-23 2012-11-24 Upm Kymmene Corp Menetelmä ja laitteisto hydroksikarboksyylihappotuotteen valmistamiseksi ja valkaisusuodatteen käyttö
FI20115497A (fi) * 2011-05-23 2012-11-24 Upm Kymmene Corp Menetelmä ja laitteisto hydroksikarboksyylihappotuotteen erottamiseksi
US20140051136A1 (en) 2012-08-10 2014-02-20 Opx Biotechnologies, Inc. Micoorganisms and Methods for the Production of Fatty Acids and Fatty Acid Derived Products
CN103714638B (zh) * 2013-03-15 2015-09-30 福建联迪商用设备有限公司 一种快速定位终端主密钥下载失败的方法及系统
US20150119601A1 (en) 2013-03-15 2015-04-30 Opx Biotechnologies, Inc. Monofunctional mcr + 3-hp dehydrogenase
US9512057B2 (en) 2013-03-15 2016-12-06 Cargill, Incorporated 3-hydroxypropionic acid compositions
JP6603658B2 (ja) 2013-07-19 2019-11-06 カーギル インコーポレイテッド 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
RU2675823C2 (ru) * 2013-09-06 2018-12-25 Торэй Индастриз, Инк. Способ получения молочной кислоты и полимолочной кислоты
WO2015152127A1 (ja) * 2014-03-31 2015-10-08 東レ株式会社 乳酸の製造方法
CN106536474A (zh) * 2014-07-10 2017-03-22 阿彻丹尼尔斯米德兰德公司 新颖的乳酸回收方法
DE102014213637A1 (de) 2014-07-14 2016-01-14 Thyssenkrupp Ag Verfahren und Vorrichtung zur Aufkonzentration und Kristallisation von fermentierbaren Carbonsäuren
PT3174988T (pt) 2014-07-28 2022-11-25 Purac Biochem Bv Método para a preparação de ácido láctico
JP2014210825A (ja) * 2014-08-22 2014-11-13 富士フイルム株式会社 プロセシンググルコシダーゼ阻害剤
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
US9758463B1 (en) 2014-09-17 2017-09-12 Nippon Shokubai Co., Ltd. Method for producing vapor composition containing lactic acid
EP3577227A4 (en) 2017-02-02 2020-12-30 Cargill Inc. GENETICALLY MODIFIED CELLS PRODUCING C6-C10 FATTY ACID DERIVATIVES
EP3692159A1 (en) * 2017-10-02 2020-08-12 Metabolic Explorer Method for producing organic acid salts from fermentation broth
CN109096097A (zh) * 2018-08-30 2018-12-28 河北乐开节能科技股份有限公司 一种制取高纯度聚合级结晶乳酸的方法
CN115989212A (zh) 2020-05-04 2023-04-18 大塚制药株式会社 用于合成无水乳酸的方法
US20230271913A1 (en) * 2020-07-31 2023-08-31 Mitsubishi Gas Chemical Company, Inc. Method for producing a-hydroxy carboxylic acid composition
NL2028900B1 (en) 2021-08-02 2023-02-17 Arapaha B V A method of closed loop recycling of polylactic acid
EP4392483A1 (en) * 2021-08-26 2024-07-03 Futerro S.A. Valorisation of lactic acid stream in the production process of polylactic acid
WO2023025818A1 (en) * 2021-08-26 2023-03-02 Futerro S.A. Valorisation of d-lactic acid stream by l/d separation in the production process of l-polylactic acid
CN114276232A (zh) * 2021-10-28 2022-04-05 欧尚元(天津)有限公司 一种超纯级乳酸的制备方法及其制备装置

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JP2830896B2 (ja) 1993-11-17 1998-12-02 株式会社島津製作所 ラクチドの製造法
JPH07165753A (ja) 1993-12-08 1995-06-27 Musashino Kagaku Kenkyusho:Kk ラクチドの精製方法
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JPH10204156A (ja) * 1997-01-17 1998-08-04 Kyowa Yuka Kk ポリヒドロキシカルボン酸の製造方法
JPH10279577A (ja) * 1997-04-04 1998-10-20 Shimadzu Corp 食品添加物用ラクチド及びラクチドの精製方法
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ES2436509T3 (es) * 2009-07-16 2014-01-02 Purac Biochem Bv Composición líquida de ácido láctico y método para su preparación

Also Published As

Publication number Publication date
BRPI0009229B8 (pt) 2021-05-25
DE60014047D1 (de) 2004-10-28
EP1163200B9 (en) 2005-03-16
BR0009229B1 (pt) 2012-12-11
WO2000056693A1 (en) 2000-09-28
ATE276994T1 (de) 2004-10-15
JP6045531B2 (ja) 2016-12-14
EP1163200A1 (en) 2001-12-19
AU3575700A (en) 2000-10-09
CN1285559C (zh) 2006-11-22
DE60014047T2 (de) 2006-02-23
DK1163200T3 (da) 2004-11-01
JP2011074084A (ja) 2011-04-14
CN1344241A (zh) 2002-04-10
US6630603B1 (en) 2003-10-07
JP2002540090A (ja) 2002-11-26
JP2014193895A (ja) 2014-10-09
EP1163200B1 (en) 2004-09-22
BR0009229A (pt) 2001-12-26

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