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ES2177024T3 - Empleo de la fanquinoma para el tratamiento de la enfermedaad de alzheimer. - Google Patents

Empleo de la fanquinoma para el tratamiento de la enfermedaad de alzheimer.

Info

Publication number
ES2177024T3
ES2177024T3 ES98930970T ES98930970T ES2177024T3 ES 2177024 T3 ES2177024 T3 ES 2177024T3 ES 98930970 T ES98930970 T ES 98930970T ES 98930970 T ES98930970 T ES 98930970T ES 2177024 T3 ES2177024 T3 ES 2177024T3
Authority
ES
Spain
Prior art keywords
alzheimer
disease
treatment
fanquinoma
employment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98930970T
Other languages
English (en)
Inventor
Michel Xilinas
Panayotis Nikolas Gerolymatos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PN Gerolymatos SA
Original Assignee
PN Gerolymatos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PN Gerolymatos SA filed Critical PN Gerolymatos SA
Application granted granted Critical
Publication of ES2177024T3 publication Critical patent/ES2177024T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Empleo de fanquinona para la elaboración de una composición farmacéutica para el tratamiento o prevención de la enfermedad de Alzheimer.
ES98930970T 1997-08-21 1998-07-17 Empleo de la fanquinoma para el tratamiento de la enfermedaad de alzheimer. Expired - Lifetime ES2177024T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GR97100330 1997-08-21
GR97100507 1997-12-31

Publications (1)

Publication Number Publication Date
ES2177024T3 true ES2177024T3 (es) 2002-12-01

Family

ID=26316681

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98930970T Expired - Lifetime ES2177024T3 (es) 1997-08-21 1998-07-17 Empleo de la fanquinoma para el tratamiento de la enfermedaad de alzheimer.

Country Status (24)

Country Link
US (2) US6670369B1 (es)
EP (1) EP1007040B1 (es)
JP (1) JP2001513558A (es)
CN (1) CN1145482C (es)
AT (1) ATE217191T1 (es)
AU (1) AU741782B2 (es)
BG (1) BG64300B1 (es)
BR (1) BR9814945A (es)
CA (1) CA2301706C (es)
CZ (1) CZ299739B6 (es)
DE (1) DE69805305T2 (es)
DK (1) DK1007040T3 (es)
EA (1) EA002526B1 (es)
ES (1) ES2177024T3 (es)
HU (1) HUP0004331A3 (es)
IL (1) IL134263A (es)
IS (1) IS1910B (es)
NO (1) NO317770B1 (es)
NZ (1) NZ502565A (es)
PL (1) PL191208B1 (es)
PT (1) PT1007040E (es)
SK (1) SK284708B6 (es)
TR (1) TR200000455T2 (es)
WO (1) WO1999009981A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7045531B1 (en) 1997-03-11 2006-05-16 The General Hospital Corporation Composition comprising a metal chelator and a method of treating amyloidosis by administering the metal chelator
US5994323A (en) * 1997-12-31 1999-11-30 P.N. Gerolymatos S.A. Pharmaceutical compositions comprising clioquinol in combination with vitamin B12 and therapeutic and prophylactic uses thereof
US6323218B1 (en) 1998-03-11 2001-11-27 The General Hospital Corporation Agents for use in the treatment of Alzheimer's disease
US6638711B1 (en) 1999-04-29 2003-10-28 The General Hospital Corporation Methods for identifying an agent that inhibits oxygen-dependent hydrogen peroxide formation activity but does not inhibit superoxide-dependent hydrogen peroxide formation
JP2002534386A (ja) 1999-01-07 2002-10-15 パイ・ニュー・ゲロリュマトス・ソシエテ・アノニム 記憶欠陥の治療又は予防にファンキノンを使用する方法
WO2001082911A2 (en) * 2000-04-28 2001-11-08 Gerolymatos P N Sa TREATMENT OF PATHOLOGICAL CONDITIONS INFLUENCED BY THE ACTION OF MATRIX METALLOPROTEINASES (MMPs) USING CLIOQUINOL
WO2001082912A2 (en) * 2000-04-28 2001-11-08 Gerolymatos P N Sa TREATMENT OF PATHOLOGICAL CONDITIONS INFLUENCED BY THE ACTION OF MATRIX METALLOPROTEINASES (MMPs) USING PHANQUINONE
AU7602100A (en) 2000-08-18 2002-03-04 Gen Hospital Corp Method for the identification of agents that inhibit or promote cataracts and uses thereof
FR2818551B1 (fr) * 2000-12-22 2007-06-01 Claude Marc Pierre Hannoun Utilisation de chelateurs pour le traitement des maladies a prions
AU2002950217A0 (en) 2002-07-16 2002-09-12 Prana Biotechnology Limited 8- Hydroxy Quinoline Derivatives
WO2004080208A1 (ja) * 2003-03-11 2004-09-23 Kaneka Corporation コエンザイムq10を含有した水中油型乳化組成物、及びその製法
WO2006117660A2 (en) * 2005-05-04 2006-11-09 Clio Pharmaceutical Corporation Method for treating cancer, coronary, inflammatory and macular disease, combining the modulation of zinc- and/or copper dependent proteins
PL3137093T3 (pl) * 2014-04-29 2018-06-29 Affiris Ag Leczenie i profilaktyka choroby Alzheimera (AD)

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617417A1 (de) * 1966-12-08 1971-03-25 Ciba Geigy Pharmazeutisches Praeparat
DE1804736A1 (de) * 1967-11-02 1969-06-26 Ciba Geigy Pharmazeutisches Praeparat
IL40311A (en) 1972-09-06 1973-04-30 Pharmaplantex Ltd Pharmaceutical preparation for the treatment of gastro-intestinal troubles containing phanquone and furazolidone
GB1472257A (en) * 1973-09-10 1977-05-04 Christiaens Sa A Derivative of 4-hydroxy-5-azacoumarin
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US4981844A (en) * 1988-10-04 1991-01-01 University Of Cincinnati Method to improve immune response and resistance to infection following surgery by diet composition
US5091391A (en) * 1990-08-16 1992-02-25 University Of Pittsburgh Of The Commonwealth System Of Higher Education Method of resisting neurodegenerative disorders
US6165500A (en) * 1990-08-24 2000-12-26 Idea Ag Preparation for the application of agents in mini-droplets
AP387A (en) * 1991-09-13 1995-07-31 Siegbert Heinrich Bissbort Therapeutical uses of L-methionine and compositions thereof.
WO1993010459A1 (en) 1991-11-12 1993-05-27 The University Of Melbourne A method for assaying and treating alzheimer's disease
GB9126874D0 (en) * 1991-12-18 1992-02-19 Wellcome Found Medicaments
EP0713392A1 (en) * 1994-05-11 1996-05-29 P.N. Gerolymatos S.A. Use of clioquinol for treating helicobacter, including h. pylori, infections and related diseases
WO1997046526A1 (en) 1996-06-07 1997-12-11 Eisai Co., Ltd. Stable polymorphs of donepezil (1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine) hydrochloride and process for production
CZ292411B6 (cs) 1996-08-13 2003-09-17 P. N. Gerolymatos S. A. Farmaceutický prostředek
WO1998040071A1 (en) 1997-03-11 1998-09-17 The General Hospital Corporation Identification of agents for use in the treatment of alzheimer's disease
US5980882A (en) * 1997-04-16 1999-11-09 Medeva Pharmaceuticals Manufacturing Drug-resin complexes stabilized by chelating agents
US5980914A (en) 1997-08-22 1999-11-09 P.N. Gerolymatos S.A. Clioquinol for the treatment of Parkinson's disease
US5994323A (en) 1997-12-31 1999-11-30 P.N. Gerolymatos S.A. Pharmaceutical compositions comprising clioquinol in combination with vitamin B12 and therapeutic and prophylactic uses thereof
JP2002534386A (ja) * 1999-01-07 2002-10-15 パイ・ニュー・ゲロリュマトス・ソシエテ・アノニム 記憶欠陥の治療又は予防にファンキノンを使用する方法
WO2001082912A2 (en) 2000-04-28 2001-11-08 Gerolymatos P N Sa TREATMENT OF PATHOLOGICAL CONDITIONS INFLUENCED BY THE ACTION OF MATRIX METALLOPROTEINASES (MMPs) USING PHANQUINONE
WO2001082911A2 (en) 2000-04-28 2001-11-08 Gerolymatos P N Sa TREATMENT OF PATHOLOGICAL CONDITIONS INFLUENCED BY THE ACTION OF MATRIX METALLOPROTEINASES (MMPs) USING CLIOQUINOL

Also Published As

Publication number Publication date
PL191208B1 (pl) 2006-03-31
TR200000455T2 (tr) 2000-09-21
BG104179A (en) 2000-10-31
CA2301706C (en) 2005-10-04
IL134263A0 (en) 2001-04-30
SK2062000A3 (en) 2000-08-14
PL338673A1 (en) 2000-11-20
BR9814945A (pt) 2000-09-05
ATE217191T1 (de) 2002-05-15
AU8124198A (en) 1999-03-16
WO1999009981A1 (en) 1999-03-04
CN1267218A (zh) 2000-09-20
EP1007040A1 (en) 2000-06-14
EP1007040B1 (en) 2002-05-08
NO20000771L (no) 2000-04-25
HK1029937A1 (en) 2001-04-20
AU741782B2 (en) 2001-12-06
DE69805305T2 (de) 2002-12-05
IL134263A (en) 2006-04-10
CZ299739B6 (cs) 2008-11-05
US7629354B2 (en) 2009-12-08
IS5366A (is) 2000-01-28
US20050003018A1 (en) 2005-01-06
NO317770B1 (no) 2004-12-13
HUP0004331A2 (hu) 2001-05-28
EA002526B1 (ru) 2002-06-27
CZ2000611A3 (cs) 2000-08-16
SK284708B6 (sk) 2005-09-08
IS1910B (is) 2003-12-31
NZ502565A (en) 2002-03-01
BG64300B1 (bg) 2004-09-30
US6670369B1 (en) 2003-12-30
EA200000242A1 (ru) 2000-08-28
DE69805305D1 (de) 2002-06-13
PT1007040E (pt) 2002-10-31
CA2301706A1 (en) 1999-03-04
DK1007040T3 (da) 2002-08-26
NO20000771D0 (no) 2000-02-16
CN1145482C (zh) 2004-04-14
JP2001513558A (ja) 2001-09-04
HUP0004331A3 (en) 2001-09-28

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