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ES2165803A1 - Nueva sal de un derivado azo del acido 5-aminosalicilico - Google Patents

Nueva sal de un derivado azo del acido 5-aminosalicilico

Info

Publication number
ES2165803A1
ES2165803A1 ES200000996A ES200000996A ES2165803A1 ES 2165803 A1 ES2165803 A1 ES 2165803A1 ES 200000996 A ES200000996 A ES 200000996A ES 200000996 A ES200000996 A ES 200000996A ES 2165803 A1 ES2165803 A1 ES 2165803A1
Authority
ES
Spain
Prior art keywords
sodium salt
phenyl
aminosalicylic acid
methyl
azo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200000996A
Other languages
English (en)
Other versions
ES2165803B1 (es
Inventor
Elena Carceller
Jorge Salas
Jose Ignacio Escamilla
Joaquim Ramis
Javier Forn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noucor Health SA
Original Assignee
J Uriach y Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by J Uriach y Cia SA filed Critical J Uriach y Cia SA
Priority to ES200000996A priority Critical patent/ES2165803B1/es
Priority to ARP010101685A priority patent/AR033363A1/es
Priority to AU2001273937A priority patent/AU2001273937A1/en
Priority to US10/257,262 priority patent/US6809087B2/en
Priority to ES01940316T priority patent/ES2291320T3/es
Priority to KR1020027013473A priority patent/KR100859296B1/ko
Priority to PT01940316T priority patent/PT1272490E/pt
Priority to PCT/EP2001/004109 priority patent/WO2001077109A2/en
Priority to MXPA02009934A priority patent/MXPA02009934A/es
Priority to EP01940316A priority patent/EP1272490B1/en
Priority to JP2001575582A priority patent/JP4597463B2/ja
Priority to DK01940316T priority patent/DK1272490T3/da
Priority to AT01940316T priority patent/ATE372999T1/de
Priority to CA2405741A priority patent/CA2405741C/en
Priority to BR0109935-3A priority patent/BR0109935A/pt
Priority to KR1020087012339A priority patent/KR100933646B1/ko
Priority to DE60130444T priority patent/DE60130444T2/de
Publication of ES2165803A1 publication Critical patent/ES2165803A1/es
Priority to NO20024878A priority patent/NO323955B1/no
Priority to HK03104473.5A priority patent/HK1052184B/zh
Application granted granted Critical
Publication of ES2165803B1 publication Critical patent/ES2165803B1/es
Priority to CY20071101589T priority patent/CY1107090T1/el
Priority to JP2010094382A priority patent/JP2010159293A/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Nueva sal de un derivado azo del acido 5-aminosalicilico. La presente invención se refiere a la sal sódica del ácido (Z)-2- hidroxi-5[[4-[3-[4-[(2-metil-1 H-imidazo[4,5-c]piridin-1- il)metil]-1-piperidinil]-3-oxo-1-fenil-1- propeni]fenil]azo]benzoico, así como a las composiciones farmacéuticas que la contienen, a un procedimiento para su preparación y a su uso en la fabricación de medicamentos útiles para el tratamiento o prevención de la enfermedad inflamatoria intestinal.
ES200000996A 2000-04-10 2000-04-10 Nueva sal de un derivado azo del acido 5-aminosalicilico Expired - Fee Related ES2165803B1 (es)

Priority Applications (21)

Application Number Priority Date Filing Date Title
ES200000996A ES2165803B1 (es) 2000-04-10 2000-04-10 Nueva sal de un derivado azo del acido 5-aminosalicilico
ARP010101685A AR033363A1 (es) 2000-04-10 2001-04-09 Nueva sal de un derivado azo del acido 5-aminosalicilico
CA2405741A CA2405741C (en) 2000-04-10 2001-04-10 Sodium salt of an azo derivative of 5-aminosalicylic acid
ES01940316T ES2291320T3 (es) 2000-04-10 2001-04-10 Sal sodica de un derivado azo de acido 5-aminosalicilico.
KR1020027013473A KR100859296B1 (ko) 2000-04-10 2001-04-10 5-아미노살리실산의 아조 유도체의 나트륨 염
PT01940316T PT1272490E (pt) 2000-04-10 2001-04-10 Novo sal de um derivado azo do ácido 5-aminossalicílico
PCT/EP2001/004109 WO2001077109A2 (en) 2000-04-10 2001-04-10 Sodium salt of an azo derivative of 5-aminosalicylic acid
MXPA02009934A MXPA02009934A (es) 2000-04-10 2001-04-10 Nueva sal de un derivado azo del acido 5-aminosalicilico.
EP01940316A EP1272490B1 (en) 2000-04-10 2001-04-10 Sodium salt of an azo derivative of 5-aminosalicylic acid
JP2001575582A JP4597463B2 (ja) 2000-04-10 2001-04-10 ５−アミノサリチル酸のアゾ誘導体の新規な塩
AU2001273937A AU2001273937A1 (en) 2000-04-10 2001-04-10 New salt of an azo derivative of 5-aminosalicylic acid
AT01940316T ATE372999T1 (de) 2000-04-10 2001-04-10 Natrium salz eines 5-aminosalicylsäure azoderivates
US10/257,262 US6809087B2 (en) 2000-04-10 2001-04-10 Sodium salt of an azo derivative of 5-aminosalicylic acid
BR0109935-3A BR0109935A (pt) 2000-04-10 2001-04-10 Sal de um derivado do ácido 5-amino salicìlico
KR1020087012339A KR100933646B1 (ko) 2000-04-10 2001-04-10 5-아미노살리실산의 아조 유도체의 나트륨 염
DE60130444T DE60130444T2 (de) 2000-04-10 2001-04-10 Natrium salz eines 5-aminosalicylsäure azoderivates
DK01940316T DK1272490T3 (da) 2000-04-10 2001-04-10 Natriumsalt af et azoderivat af 5-aminosalicylsyre
NO20024878A NO323955B1 (no) 2000-04-10 2002-10-09 Natriumsalt av et azoderivat av 5-aminosalisylsyre, farmasoytisk preparat, anvendelse av natriumsaltet for fremstilling av et medikament og fremgangsmate for fremstilling av nariumsaltet
HK03104473.5A HK1052184B (zh) 2000-04-10 2003-06-21 5-氨基水楊酸的偶氮衍生物的鈉鹽
CY20071101589T CY1107090T1 (el) 2000-04-10 2007-12-07 Αλας νατριου ενος αζο παραγωγου του 5-αμινοσαλικυλικου οξεος
JP2010094382A JP2010159293A (ja) 2000-04-10 2010-04-15 ５−アミノサリチル酸のアゾ誘導体のナトリウム塩

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200000996A ES2165803B1 (es) 2000-04-10 2000-04-10 Nueva sal de un derivado azo del acido 5-aminosalicilico

Publications (2)

Publication Number Publication Date
ES2165803A1 true ES2165803A1 (es) 2002-03-16
ES2165803B1 ES2165803B1 (es) 2003-09-16

Family

ID=8493217

Family Applications (2)

Application Number Title Priority Date Filing Date
ES200000996A Expired - Fee Related ES2165803B1 (es) 2000-04-10 2000-04-10 Nueva sal de un derivado azo del acido 5-aminosalicilico
ES01940316T Expired - Lifetime ES2291320T3 (es) 2000-04-10 2001-04-10 Sal sodica de un derivado azo de acido 5-aminosalicilico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES01940316T Expired - Lifetime ES2291320T3 (es) 2000-04-10 2001-04-10 Sal sodica de un derivado azo de acido 5-aminosalicilico.

Country Status (18)

Country Link
US (1) US6809087B2 (es)
EP (1) EP1272490B1 (es)
JP (2) JP4597463B2 (es)
KR (2) KR100933646B1 (es)
AR (1) AR033363A1 (es)
AT (1) ATE372999T1 (es)
AU (1) AU2001273937A1 (es)
BR (1) BR0109935A (es)
CA (1) CA2405741C (es)
CY (1) CY1107090T1 (es)
DE (1) DE60130444T2 (es)
DK (1) DK1272490T3 (es)
ES (2) ES2165803B1 (es)
HK (1) HK1052184B (es)
MX (1) MXPA02009934A (es)
NO (1) NO323955B1 (es)
PT (1) PT1272490E (es)
WO (1) WO2001077109A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1642885B1 (en) 2000-08-29 2009-11-11 Biocon Limited Use of a pharmaceutical composition containing a para-aminophenyl acetic acid derivative for treating inflammatory conditions of the gastrointestinal tract
US8048924B2 (en) 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
PL1773767T3 (pl) 2004-07-07 2016-07-29 Biocon Ltd Synteza azowo związanych związków immunoregulacyjnych

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4312806A (en) * 1981-03-02 1982-01-26 G. D. Searle & Co. Method and compounds for treating inflammatory bowel disease
WO1992003423A1 (en) * 1990-08-15 1992-03-05 British Bio-Technology Limited Benzimidazole derivatives, process for their preparation and application
WO1996014317A1 (en) * 1994-11-07 1996-05-17 J. Uriach & Cia. S.A. Novel piperidine derivatives with paf antagonist activity
WO1997009329A1 (en) * 1995-09-08 1997-03-13 J. Uriach & Cia. S.A. Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4312806A (en) * 1981-03-02 1982-01-26 G. D. Searle & Co. Method and compounds for treating inflammatory bowel disease
WO1992003423A1 (en) * 1990-08-15 1992-03-05 British Bio-Technology Limited Benzimidazole derivatives, process for their preparation and application
WO1996014317A1 (en) * 1994-11-07 1996-05-17 J. Uriach & Cia. S.A. Novel piperidine derivatives with paf antagonist activity
WO1997009329A1 (en) * 1995-09-08 1997-03-13 J. Uriach & Cia. S.A. Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease

Also Published As

Publication number Publication date
PT1272490E (pt) 2007-11-08
WO2001077109A3 (en) 2001-12-27
KR20020084306A (ko) 2002-11-05
JP2003530397A (ja) 2003-10-14
KR100859296B1 (ko) 2008-09-19
BR0109935A (pt) 2003-05-27
HK1052184B (zh) 2007-11-16
NO323955B1 (no) 2007-07-23
ATE372999T1 (de) 2007-09-15
NO20024878D0 (no) 2002-10-09
HK1052184A1 (en) 2003-09-05
AR033363A1 (es) 2003-12-17
DE60130444D1 (de) 2007-10-25
KR20080053417A (ko) 2008-06-12
CA2405741A1 (en) 2001-10-18
WO2001077109A2 (en) 2001-10-18
DE60130444T2 (de) 2008-06-05
JP4597463B2 (ja) 2010-12-15
CY1107090T1 (el) 2012-10-24
ES2291320T3 (es) 2008-03-01
EP1272490A2 (en) 2003-01-08
NO20024878L (no) 2002-12-05
CA2405741C (en) 2010-11-02
US6809087B2 (en) 2004-10-26
EP1272490B1 (en) 2007-09-12
JP2010159293A (ja) 2010-07-22
KR100933646B1 (ko) 2009-12-23
AU2001273937A1 (en) 2001-10-23
ES2165803B1 (es) 2003-09-16
DK1272490T3 (da) 2008-01-21
MXPA02009934A (es) 2004-08-19
US20030176401A1 (en) 2003-09-18

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