ES2161187B1 - DEVICES FOR SUPPLY OF PHARMACOS AND METHODS FOR THE TREATMENT OF VIRAL AND MICROBIAL INFECTIONS AND EXTENUATION SYNDROMES. - Google Patents
DEVICES FOR SUPPLY OF PHARMACOS AND METHODS FOR THE TREATMENT OF VIRAL AND MICROBIAL INFECTIONS AND EXTENUATION SYNDROMES.Info
- Publication number
- ES2161187B1 ES2161187B1 ES009950072A ES9950072A ES2161187B1 ES 2161187 B1 ES2161187 B1 ES 2161187B1 ES 009950072 A ES009950072 A ES 009950072A ES 9950072 A ES9950072 A ES 9950072A ES 2161187 B1 ES2161187 B1 ES 2161187B1
- Authority
- ES
- Spain
- Prior art keywords
- syndromes
- treatment
- viral
- methods
- extenuation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000000813 microbial effect Effects 0.000 title abstract 2
- 208000011580 syndromic disease Diseases 0.000 title abstract 2
- 230000003612 virological effect Effects 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Se describen nuevos dispositivos para el suministro de fármacos, métodos y composiciones terapéuticas para tratar infecciones víricas y microbianas síndromes de extenuación en un animal, incluyendo un paciente humano. De acuerdo con la invención, un compuesto polar tal como dimetilformamida o dimetilsulfóxido se administra a un paciente necesitado de tratamiento, preferentemente por una transdérmica. La invención proporciona además una vacuna preparada a partir de anticuerpos recogidos del cuerpo de un paciente tratado con el método de la invención vírica.New devices for the delivery of drugs, methods and therapeutic compositions for treating viral infections and microbial exhaustion syndromes in an animal, including a human patient, are described. According to the invention, a polar compound such as dimethylformamide or dimethylsulfoxide is administered to a patient in need of treatment, preferably by a transdermal. The invention further provides a vaccine prepared from antibodies collected from the body of a patient treated with the method of the viral invention.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/874,425 US5935597A (en) | 1995-12-15 | 1997-06-13 | Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2161187A1 ES2161187A1 (en) | 2001-11-16 |
| ES2161187B1 true ES2161187B1 (en) | 2003-08-16 |
Family
ID=25363728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES009950072A Expired - Lifetime ES2161187B1 (en) | 1997-06-13 | 1998-06-09 | DEVICES FOR SUPPLY OF PHARMACOS AND METHODS FOR THE TREATMENT OF VIRAL AND MICROBIAL INFECTIONS AND EXTENUATION SYNDROMES. |
Country Status (34)
| Country | Link |
|---|---|
| EP (1) | EP1011567A4 (en) |
| JP (1) | JP4531141B2 (en) |
| KR (1) | KR20010013709A (en) |
| CN (1) | CN1260703A (en) |
| AP (1) | AP1629A (en) |
| AR (1) | AR012970A1 (en) |
| AU (1) | AU7831598A (en) |
| BG (1) | BG103997A (en) |
| BR (1) | BR9810095A (en) |
| CA (1) | CA2295176A1 (en) |
| CZ (1) | CZ298510B6 (en) |
| EA (1) | EA200000011A1 (en) |
| EE (1) | EE9900562A (en) |
| ES (1) | ES2161187B1 (en) |
| FI (1) | FI19992648A (en) |
| GB (1) | GB2341319B (en) |
| HU (1) | HUP0003034A2 (en) |
| ID (1) | ID23516A (en) |
| IL (2) | IL133396A0 (en) |
| IS (1) | IS5289A (en) |
| LT (1) | LT4714B (en) |
| LV (1) | LV12490B (en) |
| NO (1) | NO996117L (en) |
| NZ (1) | NZ501669A (en) |
| OA (1) | OA11307A (en) |
| PL (1) | PL196256B1 (en) |
| RO (1) | RO121252B1 (en) |
| SI (1) | SI20191A (en) |
| SK (1) | SK172299A3 (en) |
| TN (1) | TNSN98086A1 (en) |
| TR (1) | TR200000540T2 (en) |
| WO (1) | WO1998056325A1 (en) |
| YU (1) | YU66099A (en) |
| ZA (1) | ZA984649B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1699430A1 (en) * | 2003-12-05 | 2006-09-13 | Namibia Medical Investments (PTY) Limited | Patch |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE60941B1 (en) * | 1986-07-10 | 1994-09-07 | Elan Transdermal Ltd | Transdermal drug delivery device |
| US4855294A (en) * | 1988-09-06 | 1989-08-08 | Theratech, Inc. | Method for reducing skin irritation associated with drug/penetration enhancer compositions |
| US5534260A (en) * | 1989-02-23 | 1996-07-09 | University Of Utah | Percutaneous drug delivery system |
| US5028435A (en) * | 1989-05-22 | 1991-07-02 | Advanced Polymer Systems, Inc. | System and method for transdermal drug delivery |
| US5624912A (en) * | 1991-08-21 | 1997-04-29 | Burcoglu; Arsinur | Method of treating HIV infection and related secondary infections with defibrotide |
| ES2115756T3 (en) * | 1992-02-20 | 1998-07-01 | Merrell Pharma Inc | SULPHONIC ACID DERIVATIVES USED IN THE TREATMENT OF VIRAL DISEASES. |
| CZ182098A3 (en) * | 1995-12-15 | 1998-11-11 | Cryopreservation Technologies Cc | Preparation used during cryogenic preservation of organs and for treating viral and bacterial infections |
-
1998
- 1998-05-29 ZA ZA9804649A patent/ZA984649B/en unknown
- 1998-06-09 ES ES009950072A patent/ES2161187B1/en not_active Expired - Lifetime
- 1998-06-09 EE EEP199900562A patent/EE9900562A/en unknown
- 1998-06-09 RO RO99-01313A patent/RO121252B1/en unknown
- 1998-06-09 JP JP50311899A patent/JP4531141B2/en not_active Expired - Fee Related
- 1998-06-09 BR BR9810095-5A patent/BR9810095A/en not_active Application Discontinuation
- 1998-06-09 KR KR1019997011724A patent/KR20010013709A/en not_active Application Discontinuation
- 1998-06-09 YU YU66099A patent/YU66099A/en unknown
- 1998-06-09 HU HU0003034A patent/HUP0003034A2/en unknown
- 1998-06-09 CA CA002295176A patent/CA2295176A1/en not_active Abandoned
- 1998-06-09 IL IL13339698A patent/IL133396A0/en active IP Right Grant
- 1998-06-09 SI SI9820040A patent/SI20191A/en unknown
- 1998-06-09 GB GB9929189A patent/GB2341319B/en not_active Expired - Fee Related
- 1998-06-09 WO PCT/US1998/011956 patent/WO1998056325A1/en active IP Right Grant
- 1998-06-09 AU AU78315/98A patent/AU7831598A/en not_active Abandoned
- 1998-06-09 ID IDW20000042A patent/ID23516A/en unknown
- 1998-06-09 SK SK1722-99A patent/SK172299A3/en unknown
- 1998-06-09 EP EP98926488A patent/EP1011567A4/en not_active Withdrawn
- 1998-06-09 PL PL338439A patent/PL196256B1/en unknown
- 1998-06-09 EA EA200000011A patent/EA200000011A1/en unknown
- 1998-06-09 CZ CZ0447399A patent/CZ298510B6/en not_active IP Right Cessation
- 1998-06-09 TR TR2000/00540T patent/TR200000540T2/en unknown
- 1998-06-09 NZ NZ501669A patent/NZ501669A/en unknown
- 1998-06-09 AP APAP/P/1999/001708A patent/AP1629A/en active
- 1998-06-09 CN CN98806085A patent/CN1260703A/en active Pending
- 1998-06-11 AR ARP980102783A patent/AR012970A1/en not_active Application Discontinuation
- 1998-06-12 TN TNTNSN98086A patent/TNSN98086A1/en unknown
-
1999
- 1999-12-08 IS IS5289A patent/IS5289A/en unknown
- 1999-12-09 IL IL133396A patent/IL133396A/en not_active IP Right Cessation
- 1999-12-09 FI FI992648A patent/FI19992648A/en unknown
- 1999-12-10 OA OA9900279A patent/OA11307A/en unknown
- 1999-12-10 NO NO996117A patent/NO996117L/en not_active Application Discontinuation
- 1999-12-13 BG BG103997A patent/BG103997A/en unknown
- 1999-12-20 LT LT99-148A patent/LT4714B/en not_active IP Right Cessation
-
2000
- 2000-02-02 LV LVP-99-182A patent/LV12490B/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019142862A (en) | Devices for using nitric oxide in plasma state to treat medical conditions and diseases | |
| CY1118651T1 (en) | Azacyclic Compounds for Use in Therapeutic Treatment of Serotonin-Related Diseases | |
| DK1151009T3 (en) | Antimicrobial / endotoxin neutralizing polypeptide | |
| CU23208A3 (en) | OXAZOLIDINONAS REPLACED AND ITS USE IN THE FIELD OF THE SANGUINEA COAGULATION | |
| ATE477758T1 (en) | DISPOSABLE DEVICE FOR TREATING HUMAN EXTREMITY INFECTIONS | |
| MY124853A (en) | 4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives. | |
| PT1267897E (en) | TREATMENT OF CONGESTIVE CARDIAC INSUFFICIENCY WITH PREVIOUSLY TREATED AUTOLOGOUS BLOOD | |
| BR0316157A (en) | 4-Amino-5-phenyl-7-cyclohexyl-pyrrolo [2,3-d] pyrimidine derivatives | |
| NZ591525A (en) | Methods of treatment of complicated skin and skin structure infections using single doses of oritavancin | |
| DE60018409D1 (en) | USE OF ANTISEPTICA FOR THE PREPARATION OF MEDICAMENTS FOR THE PROPHYLAXIS AND THE TREATMENT OF INFECTIONS AND / OR FUNCTIONAL TISSUE FORMATIONS IN THE BODY'S INSECTS | |
| MXPA00010254A (en) | The treatment of sexual dysfunction in certain patient groups. | |
| ES2161187B1 (en) | DEVICES FOR SUPPLY OF PHARMACOS AND METHODS FOR THE TREATMENT OF VIRAL AND MICROBIAL INFECTIONS AND EXTENUATION SYNDROMES. | |
| DK1251850T3 (en) | Use of a combination preparation in cancer treatment | |
| DE69929616D1 (en) | OXYHUMIC ACID AND ITS USE FOR THE TREATMENT OF DIFFERENT DISORDER | |
| HUP9903679A2 (en) | Use of olanzapine for the preparation of pharmaceutical compositions treating bipolar disorder | |
| RU2009117809A (en) | METHOD FOR TREATING VAGINAL INFECTIONS | |
| RU2285524C2 (en) | Method for treatment of acute suppurative maxillary sinusitis | |
| RU2000104538A (en) | METHOD FOR HIP JOINT PROSTHETIS UNDER THE CONSEQUENCES OF METATUBERCULOSIS COXIT | |
| DK1150981T3 (en) | Therapeutic necleoside compound | |
| RU2020123217A (en) | Anti-SARS-CoV-2 virus agent Antiprovir | |
| CO5251402A1 (en) | METHOD FOR TREATING PARKINSON EVIL THROUGH THE ADMINISTRATION OF (-) - 5-CETO-2-N, N-DI-N-PROPYLAMINE TETRAHYDROTETRALINE | |
| ECSP034842A (en) | DERIVATIVES OF 4-AMINO-5-PHENYL-7-CYCLLOBUTIL-PIRROLO [2,3-D] PYRIMIDINE | |
| RU2008142658A (en) | METHOD FOR TREATING INFECTIOUS DISEASES OF THE NERVOUS SYSTEM | |
| PE20030552A1 (en) | THERAPEUTIC APPLICATION OF SELECTIVE AGONISTS OF THE ESTROGENORECEPTOR BETA (ERß) TO CAUSE SOMATOTROPES, ORGANOTROPES AND ANTIATABOLIC EFFECTS | |
| TH80272A (en) | Organic use |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC2A | Transfer of patent | ||
| EC2A | Search report published |
Date of ref document: 20011116 Kind code of ref document: A1 Effective date: 20011116 |
|
| FG2A | Definitive protection |
Ref document number: 2161187B1 Country of ref document: ES |
|
| FA2A | Application withdrawn |
Effective date: 20050301 |