ES2161187A1 - Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes - Google Patents
Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromesInfo
- Publication number
- ES2161187A1 ES2161187A1 ES009950072A ES9950072A ES2161187A1 ES 2161187 A1 ES2161187 A1 ES 2161187A1 ES 009950072 A ES009950072 A ES 009950072A ES 9950072 A ES9950072 A ES 9950072A ES 2161187 A1 ES2161187 A1 ES 2161187A1
- Authority
- ES
- Spain
- Prior art keywords
- viral
- treatment
- methods
- drug delivery
- delivery devices
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title abstract 3
- 208000010399 Wasting Syndrome Diseases 0.000 title abstract 2
- 238000012377 drug delivery Methods 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 230000000813 microbial effect Effects 0.000 title abstract 2
- 230000003612 virological effect Effects 0.000 title abstract 2
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Novel drug delivery devices, methods and therapeutic compositions are described for treating viral and microbial infections and wasting syndromes in an animal, including a human patient. According to the invention, a polar compound such as dimethylformamide or dimethylsulfoxide is administered to a patient in need of treatment, preferably by a transdermal route. The invention further provides a vaccine prepared from antibodies harvested from the body of a patient treated by the method of the invention for a viral infection.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/874,425 US5935597A (en) | 1995-12-15 | 1997-06-13 | Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2161187A1 true ES2161187A1 (en) | 2001-11-16 |
| ES2161187B1 ES2161187B1 (en) | 2003-08-16 |
Family
ID=25363728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES009950072A Expired - Lifetime ES2161187B1 (en) | 1997-06-13 | 1998-06-09 | DEVICES FOR SUPPLY OF PHARMACOS AND METHODS FOR THE TREATMENT OF VIRAL AND MICROBIAL INFECTIONS AND EXTENUATION SYNDROMES. |
Country Status (34)
| Country | Link |
|---|---|
| EP (1) | EP1011567A4 (en) |
| JP (1) | JP4531141B2 (en) |
| KR (1) | KR20010013709A (en) |
| CN (1) | CN1260703A (en) |
| AP (1) | AP1629A (en) |
| AR (1) | AR012970A1 (en) |
| AU (1) | AU7831598A (en) |
| BG (1) | BG103997A (en) |
| BR (1) | BR9810095A (en) |
| CA (1) | CA2295176A1 (en) |
| CZ (1) | CZ298510B6 (en) |
| EA (1) | EA200000011A1 (en) |
| EE (1) | EE9900562A (en) |
| ES (1) | ES2161187B1 (en) |
| FI (1) | FI19992648A (en) |
| GB (1) | GB2341319B (en) |
| HU (1) | HUP0003034A2 (en) |
| ID (1) | ID23516A (en) |
| IL (2) | IL133396A0 (en) |
| IS (1) | IS5289A (en) |
| LT (1) | LT4714B (en) |
| LV (1) | LV12490B (en) |
| NO (1) | NO996117L (en) |
| NZ (1) | NZ501669A (en) |
| OA (1) | OA11307A (en) |
| PL (1) | PL196256B1 (en) |
| RO (1) | RO121252B1 (en) |
| SI (1) | SI20191A (en) |
| SK (1) | SK172299A3 (en) |
| TN (1) | TNSN98086A1 (en) |
| TR (1) | TR200000540T2 (en) |
| WO (1) | WO1998056325A1 (en) |
| YU (1) | YU66099A (en) |
| ZA (1) | ZA984649B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1699430A1 (en) * | 2003-12-05 | 2006-09-13 | Namibia Medical Investments (PTY) Limited | Patch |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5135480A (en) * | 1986-07-10 | 1992-08-04 | Elan Transdermal Limited | Transdermal drug delivery device |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4855294A (en) * | 1988-09-06 | 1989-08-08 | Theratech, Inc. | Method for reducing skin irritation associated with drug/penetration enhancer compositions |
| US5534260A (en) * | 1989-02-23 | 1996-07-09 | University Of Utah | Percutaneous drug delivery system |
| US5028435A (en) * | 1989-05-22 | 1991-07-02 | Advanced Polymer Systems, Inc. | System and method for transdermal drug delivery |
| US5624912A (en) * | 1991-08-21 | 1997-04-29 | Burcoglu; Arsinur | Method of treating HIV infection and related secondary infections with defibrotide |
| ES2115756T3 (en) * | 1992-02-20 | 1998-07-01 | Merrell Pharma Inc | SULPHONIC ACID DERIVATIVES USED IN THE TREATMENT OF VIRAL DISEASES. |
| CZ182098A3 (en) * | 1995-12-15 | 1998-11-11 | Cryopreservation Technologies Cc | Preparation used during cryogenic preservation of organs and for treating viral and bacterial infections |
-
1998
- 1998-05-29 ZA ZA9804649A patent/ZA984649B/en unknown
- 1998-06-09 ES ES009950072A patent/ES2161187B1/en not_active Expired - Lifetime
- 1998-06-09 EE EEP199900562A patent/EE9900562A/en unknown
- 1998-06-09 RO RO99-01313A patent/RO121252B1/en unknown
- 1998-06-09 JP JP50311899A patent/JP4531141B2/en not_active Expired - Fee Related
- 1998-06-09 BR BR9810095-5A patent/BR9810095A/en not_active Application Discontinuation
- 1998-06-09 KR KR1019997011724A patent/KR20010013709A/en not_active Application Discontinuation
- 1998-06-09 YU YU66099A patent/YU66099A/en unknown
- 1998-06-09 HU HU0003034A patent/HUP0003034A2/en unknown
- 1998-06-09 CA CA002295176A patent/CA2295176A1/en not_active Abandoned
- 1998-06-09 IL IL13339698A patent/IL133396A0/en active IP Right Grant
- 1998-06-09 SI SI9820040A patent/SI20191A/en unknown
- 1998-06-09 GB GB9929189A patent/GB2341319B/en not_active Expired - Fee Related
- 1998-06-09 WO PCT/US1998/011956 patent/WO1998056325A1/en active IP Right Grant
- 1998-06-09 AU AU78315/98A patent/AU7831598A/en not_active Abandoned
- 1998-06-09 ID IDW20000042A patent/ID23516A/en unknown
- 1998-06-09 SK SK1722-99A patent/SK172299A3/en unknown
- 1998-06-09 EP EP98926488A patent/EP1011567A4/en not_active Withdrawn
- 1998-06-09 PL PL338439A patent/PL196256B1/en unknown
- 1998-06-09 EA EA200000011A patent/EA200000011A1/en unknown
- 1998-06-09 CZ CZ0447399A patent/CZ298510B6/en not_active IP Right Cessation
- 1998-06-09 TR TR2000/00540T patent/TR200000540T2/en unknown
- 1998-06-09 NZ NZ501669A patent/NZ501669A/en unknown
- 1998-06-09 AP APAP/P/1999/001708A patent/AP1629A/en active
- 1998-06-09 CN CN98806085A patent/CN1260703A/en active Pending
- 1998-06-11 AR ARP980102783A patent/AR012970A1/en not_active Application Discontinuation
- 1998-06-12 TN TNTNSN98086A patent/TNSN98086A1/en unknown
-
1999
- 1999-12-08 IS IS5289A patent/IS5289A/en unknown
- 1999-12-09 IL IL133396A patent/IL133396A/en not_active IP Right Cessation
- 1999-12-09 FI FI992648A patent/FI19992648A/en unknown
- 1999-12-10 OA OA9900279A patent/OA11307A/en unknown
- 1999-12-10 NO NO996117A patent/NO996117L/en not_active Application Discontinuation
- 1999-12-13 BG BG103997A patent/BG103997A/en unknown
- 1999-12-20 LT LT99-148A patent/LT4714B/en not_active IP Right Cessation
-
2000
- 2000-02-02 LV LVP-99-182A patent/LV12490B/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5135480A (en) * | 1986-07-10 | 1992-08-04 | Elan Transdermal Limited | Transdermal drug delivery device |
Non-Patent Citations (1)
| Title |
|---|
| VIZA DIMITRI et al.: "Chemical Inducers of cell differentiation inhibit HIV in vitro". AIDS-FORSCHUNG, Vol. 4, n. 7, 1989, paginas 349-352. Resumen; pagina 350, columna 2, lineas 11-21; pagina 351, columna 2, lineas 1-4,13-14. * |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1151009T3 (en) | Antimicrobial / endotoxin neutralizing polypeptide | |
| MXPA05006940A (en) | Therapeutic formulations for the treatment of beta-amyloid related diseases. | |
| WO2003096990A3 (en) | Protein cages for the delivery of medical imaging and therapy | |
| ATE153856T1 (en) | COMPOSITION FOR STIMULATING THE IMMUNE SYSTEM | |
| DE69734215D1 (en) | Compounds with growth hormone-releasing properties | |
| RU94038043A (en) | Use of the substituted adenine derivatives for multiple sclerosis treatment | |
| ES2187798T3 (en) | PROCEDURE FOR CONSERVATION OF INFECTIOUS RECOMBINANT VIRUSES, VIRAL WATERPROOF SUSPENSION AND ITS USE AS A MEDICINAL PRODUCT. | |
| DE60227389D1 (en) | USE OF MILK SERUM APOPROTEINS IN THE PROPHYLAXIS OR TREATMENT OF MICROBIAL OR VIRUS INFECTIONS | |
| DE60018409D1 (en) | USE OF ANTISEPTICA FOR THE PREPARATION OF MEDICAMENTS FOR THE PROPHYLAXIS AND THE TREATMENT OF INFECTIONS AND / OR FUNCTIONAL TISSUE FORMATIONS IN THE BODY'S INSECTS | |
| AP9801286A0 (en) | Therapeutic compounds. | |
| DE60043886D1 (en) | FORMULATIONS WITH POVIDONE IOD FOR THE TREATMENT OF WOUNDS | |
| DE69929616D1 (en) | OXYHUMIC ACID AND ITS USE FOR THE TREATMENT OF DIFFERENT DISORDER | |
| MXPA00010254A (en) | The treatment of sexual dysfunction in certain patient groups. | |
| GB2341319A (en) | Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes | |
| AU3401093A (en) | Therapeutic agent for threatened abortion | |
| DK0950416T3 (en) | Use of TCF-II to treat cancer-related loss of body weight, anemia and TNF elevation | |
| DK82892D0 (en) | APPLICATION OF BRAIN ADDITION FROM BEES AND WHEPS FOR THE PREPARATION OF MEDICINAL PRODUCTS TO TREAT INFECTIONS | |
| HUP9903679A2 (en) | Use of olanzapine for the preparation of pharmaceutical compositions treating bipolar disorder | |
| DK1150981T3 (en) | Therapeutic necleoside compound | |
| FR2792639B1 (en) | NOVEL ANTI-HIV IMMUNOGENES (TOXOIDS), NOVEL PREPARATION METHODS AND APPLICATION FOR THE PREVENTION AND TREATMENT OF AIDS | |
| DE60003921D1 (en) | DIPHENYL-1,2,3-THIADIAZOL-3-OXIDES, COMPOSITIONS AND METHODS OF USE | |
| GEP19971029B (en) | Antiviral or antibacterial compound and method of use thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC2A | Transfer of patent | ||
| EC2A | Search report published |
Date of ref document: 20011116 Kind code of ref document: A1 Effective date: 20011116 |
|
| FG2A | Definitive protection |
Ref document number: 2161187B1 Country of ref document: ES |
|
| FA2A | Application withdrawn |
Effective date: 20050301 |