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ES2122589T3 - Preparacion y estabilizacion de suspensiones celulares. - Google Patents

Preparacion y estabilizacion de suspensiones celulares.

Info

Publication number
ES2122589T3
ES2122589T3 ES95916610T ES95916610T ES2122589T3 ES 2122589 T3 ES2122589 T3 ES 2122589T3 ES 95916610 T ES95916610 T ES 95916610T ES 95916610 T ES95916610 T ES 95916610T ES 2122589 T3 ES2122589 T3 ES 2122589T3
Authority
ES
Spain
Prior art keywords
stabilization
preparation
cellular suspensions
stabilized
cell suspensions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95916610T
Other languages
English (en)
Inventor
Vivian Granger
David Barnett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NORTH GEN HOSPITAL NHS TRUST
Northern General Hospital NHS Trust
Original Assignee
NORTH GEN HOSPITAL NHS TRUST
Northern General Hospital NHS Trust
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9406698A external-priority patent/GB9406698D0/en
Priority claimed from GB9413558A external-priority patent/GB2279653B/en
Application filed by NORTH GEN HOSPITAL NHS TRUST, Northern General Hospital NHS Trust filed Critical NORTH GEN HOSPITAL NHS TRUST
Application granted granted Critical
Publication of ES2122589T3 publication Critical patent/ES2122589T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002Partitioning blood components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00Reference solutions for assays of biological material
    • G01N2496/05Reference solutions for assays of biological material containing blood cells or plasma
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497Preparation composition [e.g., lysing or precipitation, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Ecology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Processing Of Solid Wastes (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

LAS SUSPENSIONES DE CELULAS ESTABILIZADAS SE PREPARAN MEDIANTE EL TRATAMIENTO DE LAS CELULAS CON 1) UNA SOLUCION ACUOSA DE UN COMPUESTO DE METAL PESADO, Y 2) PARA FORMALDEHIDO. LAS SUSPENSIONES DE CELULAS ESTABILIZADAS PUEDEN SER PREPARACIONES DE SANGRE COMPLETA ESTABILIZADAS PARA SU USO EN PROCEDIMIENTOS DE CONTROL DE CALIDAD.
ES95916610T 1994-04-05 1995-04-05 Preparacion y estabilizacion de suspensiones celulares. Expired - Lifetime ES2122589T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9406698A GB9406698D0 (en) 1994-04-05 1994-04-05 Preparation and stabilisation of cell suspensions
GB9413558A GB2279653B (en) 1993-07-05 1994-07-05 Stabilisation of cells with an agent comprising a heavy metal compound

Publications (1)

Publication Number Publication Date
ES2122589T3 true ES2122589T3 (es) 1998-12-16

Family

ID=26304635

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95916610T Expired - Lifetime ES2122589T3 (es) 1994-04-05 1995-04-05 Preparacion y estabilizacion de suspensiones celulares.

Country Status (16)

Country Link
US (1) US5858699A (es)
EP (1) EP0754301B1 (es)
JP (1) JPH10503008A (es)
CN (1) CN1149338A (es)
AT (1) ATE170979T1 (es)
AU (1) AU695573B2 (es)
BR (1) BR9507288A (es)
CA (1) CA2187196A1 (es)
DE (1) DE69504646T2 (es)
DK (1) DK0754301T3 (es)
ES (1) ES2122589T3 (es)
FI (1) FI963978L (es)
NO (1) NO964225L (es)
NZ (1) NZ284451A (es)
PL (1) PL176318B1 (es)
WO (1) WO1995027203A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2197168T3 (es) 1993-07-05 2004-01-01 Sheffield Teaching Hospitals National Health Service Trust Preparacion y estabilizacion de celulas.
DK0754301T3 (da) * 1994-04-05 1999-06-07 North Gen Hospital Nhs Trust Fremstilling og stabilisering af cellesuspensioner
GB2313288B (en) * 1996-05-24 2000-07-12 North Gen Hospital Nhs Trust Specimen collection fluid
EP1413874A1 (en) * 2002-10-16 2004-04-28 Streck Laboratories, Inc. Method and device for collecting and preserving cells for analysis
CN102879317B (zh) * 2003-06-18 2016-04-13 稳定技术公司 分散相和乳化液的加速稳定性评估
US20050085028A1 (en) * 2003-10-21 2005-04-21 International Business Machines Corporation Method and structure to suppress external latch-up
CN100376669C (zh) * 2005-02-25 2008-03-26 深圳迈瑞生物医疗电子股份有限公司 生物红细胞体积长期稳定的处理方法
WO2010078194A1 (en) 2008-12-30 2010-07-08 Streck, Inc. Method for screening blood using a preservative that may be in a substantially solid state form
US11634747B2 (en) * 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
NO2398912T3 (es) 2009-02-18 2018-02-10
EP2499259B1 (en) * 2009-11-09 2016-04-06 Streck Inc. Stabilization of rna in and extracting from intact cells within a blood sample
US20110224495A1 (en) * 2010-03-12 2011-09-15 Tyco Healthcare Group Lp Surgical access port
US8900864B2 (en) 2010-09-21 2014-12-02 Nordrhein-Wesfalen Krankenhausbetriebsgesellschaft Bad Oeynhausen mbH Stabilized leukocytes and their use
EP2704740B1 (en) 2011-05-04 2016-10-05 Streck, Inc. Inactivated swine flu virus and methods of preparing it
FR3005420B1 (fr) * 2013-05-07 2015-09-18 Erytech Pharma Procede de stabilisation de suspensions d'erythrocytes encapsulant un principe actif, suspensions obtenues.
CA2917912C (en) 2013-07-24 2019-09-17 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
US11506655B2 (en) 2016-07-29 2022-11-22 Streck, Inc. Suspension composition for hematology analysis control
EP3571314B1 (en) 2017-01-22 2023-12-20 Chryos, LLC Composition and method of use of the same for preserving cells for analysis

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DE1068862B (de) * 1957-05-03 1959-11-12 Penicillin-Gesellschaft Dauelsberg a Co., Göttingen Verfahren zur Verlängerung der Haltbarkeit von Blutkonserven
DE1147004B (de) * 1959-10-16 1963-04-11 Dr Med Herbert Fischer Verfahren zur Konservierung von lebenden menschlichen oder tierischen Zellpraeparaten, insbesondere von Blut und Blutbestandteilen
CA933092A (en) * 1969-04-10 1973-09-04 V. Collins Zeola Method of prolonging the viability of lymphocytes
FR2202688B1 (es) * 1972-10-17 1977-04-15 Cepbepe
US4045488A (en) * 1974-11-06 1977-08-30 Pfizer Inc. Aminophenyltetralin compounds
IT1065125B (it) * 1975-08-20 1985-02-25 Boehringer Mannheim Gmbh Processo per mantenere costante l attivita di fosfatasi alcalina e siero di controllo contenente tale fosfatasi
DE2551208C3 (de) * 1975-11-14 1981-05-27 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung einer stabilen Erythrozyten-Präparation
US4040785A (en) * 1976-10-18 1977-08-09 Technicon Instruments Corporation Lysable blood preservative composition
US4152208A (en) * 1977-03-29 1979-05-01 Hoffmann-La Roche Inc. Stabilized leucocytes
DE2828820A1 (de) * 1977-08-01 1979-02-08 Warner Lambert Co Verfahren zur herstellung einer stabilen blutplaettchensuspension und nach dem verfahren erhaltene stabile blutplaettchensuspension
US4324687A (en) * 1979-02-15 1982-04-13 Louderback Allan Lee Blood biochemistry control standard
DE2949824A1 (de) * 1979-12-12 1981-07-02 Marianne Dr. 5000 Köln Sehrbundt Verfahren zur stabilisierung von lymphozyten/thrombozytennmischsuspensionen
US4346018A (en) * 1980-06-16 1982-08-24 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4405719A (en) * 1981-05-29 1983-09-20 Coulter Electronics, Inc. Method of stabilizing platelets for determining multiple platelet parameters in reference control and calibrator compositions; diluents therefor; and combination stabilization procedures
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JPH0820452B2 (ja) * 1991-12-16 1996-03-04 株式会社いかがく 血液中糖類の微生物による消費阻止方法
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CA2123227C (en) * 1992-09-10 2009-04-28 Wayne L. Ryan Method and composition for preserving antigens and process for utilizing cytological material produced by same
ES2197168T3 (es) * 1993-07-05 2004-01-01 Sheffield Teaching Hospitals National Health Service Trust Preparacion y estabilizacion de celulas.
DK0754301T3 (da) * 1994-04-05 1999-06-07 North Gen Hospital Nhs Trust Fremstilling og stabilisering af cellesuspensioner

Also Published As

Publication number Publication date
PL176318B1 (pl) 1999-05-31
PL316657A1 (en) 1997-02-03
ATE170979T1 (de) 1998-09-15
EP0754301A1 (en) 1997-01-22
BR9507288A (pt) 1997-09-23
DE69504646T2 (de) 1999-04-29
FI963978A0 (fi) 1996-10-04
DE69504646D1 (de) 1998-10-15
CA2187196A1 (en) 1995-10-12
NO964225D0 (no) 1996-10-04
US5858699A (en) 1999-01-12
FI963978L (fi) 1996-12-02
JPH10503008A (ja) 1998-03-17
CN1149338A (zh) 1997-05-07
NO964225L (no) 1996-12-05
DK0754301T3 (da) 1999-06-07
EP0754301B1 (en) 1998-09-09
AU695573B2 (en) 1998-08-13
WO1995027203A1 (en) 1995-10-12
AU2305195A (en) 1995-10-23
NZ284451A (en) 1998-03-25

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