ES2018638A6 - Procedimiento para producir microesferas mediante reticulacion de pro-teinas. - Google Patents
Procedimiento para producir microesferas mediante reticulacion de pro-teinas.Info
- Publication number
- ES2018638A6 ES2018638A6 ES8902870A ES8902870A ES2018638A6 ES 2018638 A6 ES2018638 A6 ES 2018638A6 ES 8902870 A ES8902870 A ES 8902870A ES 8902870 A ES8902870 A ES 8902870A ES 2018638 A6 ES2018638 A6 ES 2018638A6
- Authority
- ES
- Spain
- Prior art keywords
- crosslinking
- proteins
- microspheres
- production
- emulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004132 cross linking Methods 0.000 title abstract 3
- 239000004005 microsphere Substances 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000839 emulsion Substances 0.000 abstract 2
- 150000001718 carbodiimides Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003094 microcapsule Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/11—Encapsulated compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO PARA PRODUCIR MICROESFERAS MEDIANTE RETICULACION DE PROTEINAS. CONSISTE EN REALIZAR LA RETICULACION EN UNA EMULSION CUYA FASE CONTINUA ESTA CONSTITUIDA POR UN DISOLVENTE INERTE AL QUE SE AÑADE UN AGENTE TENSIOACTIVO. Y CUYA FASE DISCONTINUA COMPRENDE UNA FASE LIQUIDA HIDROFILA QUE CONTIENE AL MENOS UNA PROTEINA, Y AÑADIR A LA EMULSION UNA CARBODIIMIDA PARA ACTIVAR LA RETICULACION Y OBTENER UN PRECIPITADO DE MICROESFERAS, TRAS LO CUAL SE SEPARA Y SE LAVA DICHO PRECIPITADO. LAS MICROESFERAS PRODUCIDAS SON UTILES PARA ACONDICIONAR COMPUESTOS DE ACTIVIDAD FARMACEUTICA O COSMETICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8810942A FR2635459B1 (fr) | 1988-08-17 | 1988-08-17 | Procede de fabrication de microspheres par reticulation de proteines, microspheres ainsi obtenues et leurs utilisations |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2018638A6 true ES2018638A6 (es) | 1991-04-16 |
Family
ID=9369356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8902870A Expired - Lifetime ES2018638A6 (es) | 1988-08-17 | 1989-08-16 | Procedimiento para producir microesferas mediante reticulacion de pro-teinas. |
Country Status (6)
Country | Link |
---|---|
JP (1) | JPH02167222A (es) |
DE (1) | DE3927073A1 (es) |
ES (1) | ES2018638A6 (es) |
FR (1) | FR2635459B1 (es) |
GB (1) | GB2224258B (es) |
IT (1) | IT1232917B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5271961A (en) * | 1989-11-06 | 1993-12-21 | Alkermes Controlled Therapeutics, Inc. | Method for producing protein microspheres |
WO1991019424A1 (en) * | 1990-06-19 | 1991-12-26 | Mars G.B. Limited | Fat substitutes and method of preparing organic microbeads |
AU7668894A (en) * | 1993-08-13 | 1995-03-14 | Vitaphore Corporation | Hydrogel-based microsphere drug delivery systems |
US7521068B2 (en) | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
DK1471887T3 (da) * | 2002-02-04 | 2010-06-07 | Elan Pharma Int Ltd | Nanopartikelkompositioner der har lysozym som overfladestabiliseringsmiddel |
JP5057501B2 (ja) * | 2005-11-25 | 2012-10-24 | 株式会社パイロットコーポレーション | マイクロカプセルの製造法ならびにマイクロカプセル及びそれを用いた表示媒体 |
US11207258B2 (en) * | 2016-01-25 | 2021-12-28 | Suntory Holdings Limited | Capsule containing functional substance and method for manufacturing said capsule |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1077842A (en) * | 1975-10-09 | 1980-05-20 | Minnesota Mining And Manufacturing Company | Albumin medicament carrier system |
US4349530A (en) * | 1980-12-11 | 1982-09-14 | The Ohio State University | Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal |
JPS58162595A (ja) * | 1982-03-19 | 1983-09-27 | Green Cross Corp:The | 徐放性アルブミン複合体の製法 |
IL74715A0 (en) * | 1984-03-27 | 1985-06-30 | Univ New Jersey Med | Biodegradable matrix and methods for producing same |
GB2160312B (en) * | 1984-04-13 | 1987-09-16 | South African Inventions | Adjuvant for immunisation |
EP0211042A1 (en) * | 1985-01-18 | 1987-02-25 | Cooper-Lipotech, Inc. | Liposome composition and method |
-
1988
- 1988-08-17 FR FR8810942A patent/FR2635459B1/fr not_active Expired - Lifetime
-
1989
- 1989-08-16 DE DE3927073A patent/DE3927073A1/de not_active Withdrawn
- 1989-08-16 ES ES8902870A patent/ES2018638A6/es not_active Expired - Lifetime
- 1989-08-16 IT IT8967705A patent/IT1232917B/it active
- 1989-08-16 GB GB8918720A patent/GB2224258B/en not_active Expired
- 1989-08-17 JP JP1210801A patent/JPH02167222A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JPH02167222A (ja) | 1990-06-27 |
GB8918720D0 (en) | 1989-09-27 |
FR2635459A1 (fr) | 1990-02-23 |
IT8967705A0 (it) | 1989-08-16 |
GB2224258A (en) | 1990-05-02 |
DE3927073A1 (de) | 1990-02-22 |
GB2224258B (en) | 1991-12-11 |
FR2635459B1 (fr) | 1992-06-19 |
IT1232917B (it) | 1992-03-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20001102 |