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ES2007625A6 - Un procedimiento para la produccion de una proteina para huesos y cartilagos. - Google Patents

Un procedimiento para la produccion de una proteina para huesos y cartilagos.

Info

Publication number
ES2007625A6
ES2007625A6 ES8701909A ES8701909A ES2007625A6 ES 2007625 A6 ES2007625 A6 ES 2007625A6 ES 8701909 A ES8701909 A ES 8701909A ES 8701909 A ES8701909 A ES 8701909A ES 2007625 A6 ES2007625 A6 ES 2007625A6
Authority
ES
Spain
Prior art keywords
osteoinductive compositions
novel osteoinductive
novel
compositions
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8701909A
Other languages
English (en)
Inventor
Elizabeth A Wang
John M Wozney
Vicki A Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetics Institute LLC
Original Assignee
Genetics Institute LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/031,346 external-priority patent/US4877864A/en
Application filed by Genetics Institute LLC filed Critical Genetics Institute LLC
Publication of ES2007625A6 publication Critical patent/ES2007625A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Indole Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PRODUCCION DE UNA PROTEINA PARA HUESOS Y CARTILAGOS. COMPRENDE LAS SIGUIENTES ETAPAS: A) TRANFORMAR UNA CELULA O LINEA CELULAR ADECUADA, SELECCIONADA ENTRE CELULAS DE MAMIFEROS, CELULAS BACTERIANAS Y CELULA DE LEVADURAS CON UNA SECUENCIA DE DNA, CODIFICANTE PARA LA SECUENCIA PEPTIDICA DE LA PROTEINA DESEADA. B) CULTIVAR LA CELULA TRANSFORMADA, AMPLIFICAR Y ESCRUTAR EL CULTIVO MEDIANTE TECNICAS DE INGENIERIA GENETICA PARA PRODUCIR LA PROTEINA DESEADA; Y C) RECUPERAR Y PURIFICAR LA PROTEINA PRODUCIDA PARA OBTENERLA O SUSTANCIALMENTE LIBRE DE OTROS MATERIALES PROTEINICOS PRODUCIDOS SIMULTANEAMENTE. ESTE PROCEDIMIENTO ES UTIL EN LA INVESTIGACION Y DESARROLLO DE LOS DEFECTOS OSEOS Y PERIODONTALES DE HUMANOS Y BOVINOS.
ES8701909A 1986-07-01 1987-06-30 Un procedimiento para la produccion de una proteina para huesos y cartilagos. Expired ES2007625A6 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US88077686A 1986-07-01 1986-07-01
US94333286A 1986-12-17 1986-12-17
US2828587A 1987-03-20 1987-03-20
US07/031,346 US4877864A (en) 1987-03-26 1987-03-26 Osteoinductive factors

Publications (1)

Publication Number Publication Date
ES2007625A6 true ES2007625A6 (es) 1989-07-01

Family

ID=27487661

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8701909A Expired ES2007625A6 (es) 1986-07-01 1987-06-30 Un procedimiento para la produccion de una proteina para huesos y cartilagos.

Country Status (18)

Country Link
EP (3) EP0313578B1 (es)
JP (3) JP2713715B2 (es)
AT (3) ATE234921T1 (es)
AU (1) AU613314B2 (es)
CA (1) CA1341212C (es)
DE (4) DE3751887T2 (es)
DK (2) DK172275B1 (es)
ES (1) ES2007625A6 (es)
GR (1) GR871028B (es)
IE (1) IE75881B1 (es)
IL (1) IL83003A (es)
LU (1) LU91005I2 (es)
MX (1) MX170919B (es)
MY (1) MY102505A (es)
NL (1) NL300116I2 (es)
NZ (1) NZ220894A (es)
PT (1) PT85225B (es)
WO (1) WO1988000205A1 (es)

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AU7783587A (en) 1988-01-29
EP1254956A2 (en) 2002-11-06
MX170919B (es) 1993-09-22
DE3751887T2 (de) 1997-03-06
NL300116I2 (nl) 2003-06-02
DE10399007I2 (de) 2006-03-16
JP3093682B2 (ja) 2000-10-03
LU91005I2 (en) 2003-03-31
DK172275B1 (da) 1998-02-16
EP1254956A3 (en) 2002-11-13
CA1341212C (en) 2001-04-10
EP1254956B1 (en) 2008-12-31
EP0313578A4 (en) 1990-10-03
JPH02500241A (ja) 1990-02-01
JPH1070989A (ja) 1998-03-17
IL83003A (en) 1995-07-31
DK53497A (da) 1997-05-09
ATE141928T1 (de) 1996-09-15
JP2729222B2 (ja) 1998-03-18
JPH06298800A (ja) 1994-10-25
DK172503B1 (da) 1998-10-26
EP0313578A1 (en) 1989-05-03
IE970378L (en) 1988-01-01
IE871739L (en) 1988-01-01
MY102505A (en) 1992-07-31
EP0688869A1 (en) 1995-12-27
IL83003A0 (en) 1987-12-20
EP0688869B1 (en) 2003-03-19
IE75881B1 (en) 1997-09-24
AU613314B2 (en) 1991-08-01
DE10399007I1 (de) 2003-07-31
ATE419349T1 (de) 2009-01-15
DE3751887D1 (de) 1996-10-02
NL300116I1 (nl) 2003-05-01
DE3752364D1 (de) 2003-04-24
ATE234921T1 (de) 2003-04-15
GR871028B (es) 1988-01-11
NZ220894A (en) 1990-05-28
JP2713715B2 (ja) 1998-02-16
DK106288D0 (da) 1988-02-29
PT85225B (pt) 1990-03-30
DE3752364T2 (de) 2004-03-04
DE3752393D1 (de) 2009-02-12
EP0313578B1 (en) 1996-08-28
DK106288A (da) 1988-04-28
PT85225A (en) 1987-08-01
WO1988000205A1 (en) 1988-01-14

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