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EP2537010A4 - Optics collection and detection system and method - Google Patents

Optics collection and detection system and method

Info

Publication number
EP2537010A4
EP2537010A4 EP11745387.8A EP11745387A EP2537010A4 EP 2537010 A4 EP2537010 A4 EP 2537010A4 EP 11745387 A EP11745387 A EP 11745387A EP 2537010 A4 EP2537010 A4 EP 2537010A4
Authority
EP
European Patent Office
Prior art keywords
illumination
cladding
devices
disclosed
sensor element
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP11745387.8A
Other languages
German (de)
French (fr)
Other versions
EP2537010A1 (en
Inventor
Adrian Fehr
Nathaniel Joseph Mccaffrey
Stephen Turner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pacific Biosciences of California Inc
Original Assignee
Pacific Biosciences of California Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44483338&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP2537010(A4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pacific Biosciences of California Inc filed Critical Pacific Biosciences of California Inc
Publication of EP2537010A1 publication Critical patent/EP2537010A1/en
Publication of EP2537010A4 publication Critical patent/EP2537010A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
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    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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    • B82Y20/00—Nanooptics, e.g. quantum optics or photonic crystals
    • C—CHEMISTRY; METALLURGY
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  • Optics & Photonics (AREA)
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  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Nanotechnology (AREA)
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  • Biomedical Technology (AREA)
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  • Crystallography & Structural Chemistry (AREA)
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  • Microelectronics & Electronic Packaging (AREA)
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Abstract

An analytical device including an optically opaque cladding, a sequencing layer including a substrate disposed below the cladding, and a waveguide assembly for receiving optical illumination and introducing illumination into the device. The illumination may be received from a top, a side edge, and a bottom of the device. The waveguide assembly may include a nanoscale aperture disposed in the substrate and extending through the cladding. The aperture defines a reaction cell for receiving a set of reactants. In various aspects, the device includes a sensor element and the illumination pathway is through the sensor element. Waveguides and illumination devices, such as plasmonic illumination devices, are also disclosed. Methods for forming and operating the devices are also disclosed.
EP11745387.8A 2010-02-19 2011-02-18 Optics collection and detection system and method Ceased EP2537010A4 (en)

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US30623510P 2010-02-19 2010-02-19
US38791610P 2010-09-29 2010-09-29
US41018910P 2010-11-04 2010-11-04
PCT/US2011/025547 WO2011103507A1 (en) 2010-02-19 2011-02-18 Optics collection and detection system and method

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EP11745384.5A Active EP2537019B1 (en) 2010-02-19 2011-02-18 Device for measuring analytical reactions
EP18204689.6A Active EP3460458B1 (en) 2010-02-19 2011-02-18 A method for nucleic acid sequencing
EP11745387.8A Ceased EP2537010A4 (en) 2010-02-19 2011-02-18 Optics collection and detection system and method
EP11745380.3A Active EP2537053B1 (en) 2010-02-19 2011-02-18 An analytical device comprising an optode array chip
EP21182582.3A Active EP3943920B1 (en) 2010-02-19 2011-02-18 Integrated analytical system and method for fluorescence measurement
EP14191733.6A Active EP2933629B1 (en) 2010-02-19 2011-02-18 System for measuring analytical reactions comprising a socket for an optode array chip
EP24157678.4A Pending EP4378584A3 (en) 2010-02-19 2011-02-18 Integrated analytical system and method for fluorescence measurement

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EP14191733.6A Active EP2933629B1 (en) 2010-02-19 2011-02-18 System for measuring analytical reactions comprising a socket for an optode array chip
EP24157678.4A Pending EP4378584A3 (en) 2010-02-19 2011-02-18 Integrated analytical system and method for fluorescence measurement

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