EE9900387A - Crystalline hydrate of (E) -4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidenemethyl) -1H-indole-2-carboxylic acid, sodium salt - Google Patents
Crystalline hydrate of (E) -4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidenemethyl) -1H-indole-2-carboxylic acid, sodium saltInfo
- Publication number
- EE9900387A EE9900387A EEP199900387A EEP9900387A EE9900387A EE 9900387 A EE9900387 A EE 9900387A EE P199900387 A EEP199900387 A EE P199900387A EE P9900387 A EEP9900387 A EE P9900387A EE 9900387 A EE9900387 A EE 9900387A
- Authority
- EE
- Estonia
- Prior art keywords
- phenylpyrrolidin
- ylidenemethyl
- indole
- dichloro
- oxo
- Prior art date
Links
- VDIRQCDDCGAGET-DHZHZOJOSA-N 4,6-dichloro-3-[(e)-(2-oxo-1-phenylpyrrolidin-3-ylidene)methyl]-1h-indole-2-carboxylic acid Chemical compound OC(=O)C=1NC2=CC(Cl)=CC(Cl)=C2C=1\C=C(C1=O)/CCN1C1=CC=CC=C1 VDIRQCDDCGAGET-DHZHZOJOSA-N 0.000 title 1
- 159000000000 sodium salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9704498.6A GB9704498D0 (en) | 1997-03-05 | 1997-03-05 | Chemical compound |
| PCT/EP1998/001146 WO1998039327A1 (en) | 1997-03-05 | 1998-03-03 | Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE9900387A true EE9900387A (en) | 2000-04-17 |
Family
ID=10808697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP199900387A EE9900387A (en) | 1997-03-05 | 1998-03-03 | Crystalline hydrate of (E) -4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidenemethyl) -1H-indole-2-carboxylic acid, sodium salt |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP0966463A1 (en) |
| JP (1) | JP2001513796A (en) |
| KR (1) | KR20000075907A (en) |
| CN (1) | CN1249750A (en) |
| AP (1) | AP9901637A0 (en) |
| AR (1) | AR011178A1 (en) |
| AU (1) | AU6825198A (en) |
| BG (1) | BG103779A (en) |
| BR (1) | BR9808305A (en) |
| CA (1) | CA2282851A1 (en) |
| CO (1) | CO4940415A1 (en) |
| EA (1) | EA199900710A1 (en) |
| EE (1) | EE9900387A (en) |
| GB (1) | GB9704498D0 (en) |
| HR (1) | HRP980114A2 (en) |
| HU (1) | HUP0002109A2 (en) |
| ID (1) | ID24207A (en) |
| IL (1) | IL131489A0 (en) |
| IS (1) | IS5166A (en) |
| NO (1) | NO994303L (en) |
| NZ (1) | NZ337315A (en) |
| OA (1) | OA11154A (en) |
| PE (1) | PE51399A1 (en) |
| PL (1) | PL335652A1 (en) |
| SK (1) | SK119699A3 (en) |
| TR (1) | TR199902117T2 (en) |
| WO (1) | WO1998039327A1 (en) |
| YU (1) | YU43499A (en) |
| ZA (1) | ZA981791B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9704499D0 (en) * | 1997-03-05 | 1997-04-23 | Glaxo Wellcome Spa | Method of manufacture |
| GB9825988D0 (en) * | 1998-11-27 | 1999-01-20 | Pfizer Ltd | Indole derivatives |
| GB9915231D0 (en) | 1999-06-29 | 1999-09-01 | Pfizer Ltd | Pharmaceutical complex |
| US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| CN110996948A (en) | 2017-06-12 | 2020-04-10 | 格莱泰施有限责任公司 | Treatment of depression with NMDA antagonists and D2/5HT2A or selective 5HT2A antagonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9321221D0 (en) * | 1993-10-14 | 1993-12-01 | Glaxo Spa | Heterocyclic compounds |
-
1997
- 1997-03-05 GB GBGB9704498.6A patent/GB9704498D0/en active Pending
-
1998
- 1998-03-03 KR KR1019997007987A patent/KR20000075907A/en not_active Application Discontinuation
- 1998-03-03 BR BR9808305-8A patent/BR9808305A/en not_active Application Discontinuation
- 1998-03-03 PE PE1998000149A patent/PE51399A1/en not_active Application Discontinuation
- 1998-03-03 YU YU43499A patent/YU43499A/en unknown
- 1998-03-03 ZA ZA9801791A patent/ZA981791B/en unknown
- 1998-03-03 HU HU0002109A patent/HUP0002109A2/en unknown
- 1998-03-03 EP EP98913613A patent/EP0966463A1/en not_active Withdrawn
- 1998-03-03 EA EA199900710A patent/EA199900710A1/en unknown
- 1998-03-03 CO CO98011404A patent/CO4940415A1/en unknown
- 1998-03-03 SK SK1196-99A patent/SK119699A3/en unknown
- 1998-03-03 AR ARP980100948A patent/AR011178A1/en unknown
- 1998-03-03 PL PL98335652A patent/PL335652A1/en unknown
- 1998-03-03 AU AU68251/98A patent/AU6825198A/en not_active Abandoned
- 1998-03-03 CN CN98803053A patent/CN1249750A/en active Pending
- 1998-03-03 JP JP53813598A patent/JP2001513796A/en active Pending
- 1998-03-03 ID IDW990976A patent/ID24207A/en unknown
- 1998-03-03 WO PCT/EP1998/001146 patent/WO1998039327A1/en not_active Application Discontinuation
- 1998-03-03 IL IL13148998A patent/IL131489A0/en unknown
- 1998-03-03 EE EEP199900387A patent/EE9900387A/en unknown
- 1998-03-03 CA CA002282851A patent/CA2282851A1/en not_active Abandoned
- 1998-03-03 NZ NZ337315A patent/NZ337315A/en unknown
- 1998-03-03 AP APAP/P/1999/001637A patent/AP9901637A0/en unknown
- 1998-03-03 TR TR1999/02117T patent/TR199902117T2/en unknown
- 1998-03-04 HR HR9704498.6A patent/HRP980114A2/en not_active Application Discontinuation
-
1999
- 1999-08-27 IS IS5166A patent/IS5166A/en unknown
- 1999-09-02 OA OA9900201A patent/OA11154A/en unknown
- 1999-09-03 NO NO994303A patent/NO994303L/en not_active Application Discontinuation
- 1999-10-04 BG BG103779A patent/BG103779A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK119699A3 (en) | 2000-05-16 |
| EP0966463A1 (en) | 1999-12-29 |
| AU6825198A (en) | 1998-09-22 |
| CO4940415A1 (en) | 2000-07-24 |
| PE51399A1 (en) | 1999-06-07 |
| IS5166A (en) | 1999-08-27 |
| NZ337315A (en) | 2001-02-23 |
| KR20000075907A (en) | 2000-12-26 |
| YU43499A (en) | 2000-12-28 |
| ID24207A (en) | 2000-07-13 |
| TR199902117T2 (en) | 2000-03-21 |
| BR9808305A (en) | 2000-05-16 |
| OA11154A (en) | 2003-04-16 |
| PL335652A1 (en) | 2000-05-08 |
| NO994303L (en) | 1999-11-03 |
| HRP980114A2 (en) | 1998-12-31 |
| ZA981791B (en) | 1999-09-03 |
| BG103779A (en) | 2000-06-30 |
| AR011178A1 (en) | 2000-08-02 |
| CA2282851A1 (en) | 1998-09-11 |
| AP9901637A0 (en) | 1999-09-30 |
| GB9704498D0 (en) | 1997-04-23 |
| EA199900710A1 (en) | 2000-04-24 |
| WO1998039327A1 (en) | 1998-09-11 |
| NO994303D0 (en) | 1999-09-03 |
| HUP0002109A2 (en) | 2001-04-28 |
| JP2001513796A (en) | 2001-09-04 |
| CN1249750A (en) | 2000-04-05 |
| IL131489A0 (en) | 2001-01-28 |
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