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AU1817700A - 1-carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of mmp-12 - Google Patents

1-carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of mmp-12

Info

Publication number
AU1817700A
AU1817700A AU18177/00A AU1817700A AU1817700A AU 1817700 A AU1817700 A AU 1817700A AU 18177/00 A AU18177/00 A AU 18177/00A AU 1817700 A AU1817700 A AU 1817700A AU 1817700 A AU1817700 A AU 1817700A
Authority
AU
Australia
Prior art keywords
mmp
carboxymethyl
oxo
selective inhibitors
derivatives useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU18177/00A
Inventor
Michael J Janusz
Alan M. Warshawsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Publication of AU1817700A publication Critical patent/AU1817700A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU18177/00A 1998-12-31 1999-11-12 1-carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of mmp-12 Abandoned AU1817700A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22445798A 1998-12-31 1998-12-31
US09224457 1998-12-31
PCT/US1999/026748 WO2000040577A1 (en) 1998-12-31 1999-11-12 1-carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of mmp-12

Publications (1)

Publication Number Publication Date
AU1817700A true AU1817700A (en) 2000-07-24

Family

ID=22840777

Family Applications (1)

Application Number Title Priority Date Filing Date
AU18177/00A Abandoned AU1817700A (en) 1998-12-31 1999-11-12 1-carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of mmp-12

Country Status (4)

Country Link
EP (1) EP1150975A1 (en)
AU (1) AU1817700A (en)
CA (1) CA2356689A1 (en)
WO (1) WO2000040577A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0100902D0 (en) 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
PL364714A1 (en) * 2001-03-15 2004-12-13 Astrazeneca Ab Metalloproteinase inhibitors
SE0100903D0 (en) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0103710D0 (en) 2001-11-07 2001-11-07 Astrazeneca Ab Compounds
SE0202539D0 (en) 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
US7648992B2 (en) 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
AU2005277432B2 (en) 2004-08-19 2011-11-24 Foresee Pharmaceuticals Co., Ltd. 5-[3-(4-benzyloxyphenylthio)-fur-2-yl]-imidazolidin-2, 4-dione and analogues as inhibitors of macrophage elastase
SE0403086D0 (en) 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
SE0403085D0 (en) 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
JP7343571B2 (en) 2018-05-15 2023-09-12 フォアシー ファーマシューティカルズ ユーエスエー，インコーポレーテッド Matrix metalloproteinase (MMP) inhibitors and methods of use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9904165A3 (en) * 1996-09-19 2002-01-28 Aventis Pharmaceuticals Inc Br 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase and use thereof

Also Published As

Publication number Publication date
CA2356689A1 (en) 2000-07-13
EP1150975A1 (en) 2001-11-07
WO2000040577A1 (en) 2000-07-13

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase