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AR011178A1 - SODIUM SALT COMPOUND OF (ACID (E) 4,6-DICHLORO-3- (2-OXO-1- FENILPIRROLIDIN-3-ILIDENO-METHYL) -1H-INDOL-2-CARBOXILICO IN ITS HYDRATED FORM, PROCESS FOR ITS PREPARATION, PHARMACEUTICAL COMPOSITION THAT CONTAINS IT AND METHOD OF TREATMENT USING SUCH COMPOUND - Google Patents

SODIUM SALT COMPOUND OF (ACID (E) 4,6-DICHLORO-3- (2-OXO-1- FENILPIRROLIDIN-3-ILIDENO-METHYL) -1H-INDOL-2-CARBOXILICO IN ITS HYDRATED FORM, PROCESS FOR ITS PREPARATION, PHARMACEUTICAL COMPOSITION THAT CONTAINS IT AND METHOD OF TREATMENT USING SUCH COMPOUND

Info

Publication number
AR011178A1
AR011178A1 ARP980100948A ARP980100948A AR011178A1 AR 011178 A1 AR011178 A1 AR 011178A1 AR P980100948 A ARP980100948 A AR P980100948A AR P980100948 A ARP980100948 A AR P980100948A AR 011178 A1 AR011178 A1 AR 011178A1
Authority
AR
Argentina
Prior art keywords
compound
preparation
treatment
sodium salt
ilideno
Prior art date
Application number
ARP980100948A
Other languages
Spanish (es)
Original Assignee
Glaxo Wellcome Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa
Publication of AR011178A1 publication Critical patent/AR011178A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

Una forma hidratada cristalina de la sal de sodio del compuesto de formula (I), los procesos para su preparacion y su uso en terapia. Dichoscompuestos son utiles para el tratamiento o prevencion de danos neurotoxicos y enfermedades degenerativas.A crystalline hydrated form of the sodium salt of the compound of formula (I), the processes for its preparation and its use in therapy. Said compounds are useful for the treatment or prevention of neurotoxic damage and degenerative diseases.

ARP980100948A 1997-03-05 1998-03-03 SODIUM SALT COMPOUND OF (ACID (E) 4,6-DICHLORO-3- (2-OXO-1- FENILPIRROLIDIN-3-ILIDENO-METHYL) -1H-INDOL-2-CARBOXILICO IN ITS HYDRATED FORM, PROCESS FOR ITS PREPARATION, PHARMACEUTICAL COMPOSITION THAT CONTAINS IT AND METHOD OF TREATMENT USING SUCH COMPOUND AR011178A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9704498.6A GB9704498D0 (en) 1997-03-05 1997-03-05 Chemical compound

Publications (1)

Publication Number Publication Date
AR011178A1 true AR011178A1 (en) 2000-08-02

Family

ID=10808697

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980100948A AR011178A1 (en) 1997-03-05 1998-03-03 SODIUM SALT COMPOUND OF (ACID (E) 4,6-DICHLORO-3- (2-OXO-1- FENILPIRROLIDIN-3-ILIDENO-METHYL) -1H-INDOL-2-CARBOXILICO IN ITS HYDRATED FORM, PROCESS FOR ITS PREPARATION, PHARMACEUTICAL COMPOSITION THAT CONTAINS IT AND METHOD OF TREATMENT USING SUCH COMPOUND

Country Status (29)

Country Link
EP (1) EP0966463A1 (en)
JP (1) JP2001513796A (en)
KR (1) KR20000075907A (en)
CN (1) CN1249750A (en)
AP (1) AP9901637A0 (en)
AR (1) AR011178A1 (en)
AU (1) AU6825198A (en)
BG (1) BG103779A (en)
BR (1) BR9808305A (en)
CA (1) CA2282851A1 (en)
CO (1) CO4940415A1 (en)
EA (1) EA199900710A1 (en)
EE (1) EE9900387A (en)
GB (1) GB9704498D0 (en)
HR (1) HRP980114A2 (en)
HU (1) HUP0002109A2 (en)
ID (1) ID24207A (en)
IL (1) IL131489A0 (en)
IS (1) IS5166A (en)
NO (1) NO994303L (en)
NZ (1) NZ337315A (en)
OA (1) OA11154A (en)
PE (1) PE51399A1 (en)
PL (1) PL335652A1 (en)
SK (1) SK119699A3 (en)
TR (1) TR199902117T2 (en)
WO (1) WO1998039327A1 (en)
YU (1) YU43499A (en)
ZA (1) ZA981791B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9704499D0 (en) * 1997-03-05 1997-04-23 Glaxo Wellcome Spa Method of manufacture
GB9825988D0 (en) * 1998-11-27 1999-01-20 Pfizer Ltd Indole derivatives
GB9915231D0 (en) 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
CN110996948A (en) 2017-06-12 2020-04-10 格莱泰施有限责任公司 Treatment of depression with NMDA antagonists and D2/5HT2A or selective 5HT2A antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9321221D0 (en) * 1993-10-14 1993-12-01 Glaxo Spa Heterocyclic compounds

Also Published As

Publication number Publication date
SK119699A3 (en) 2000-05-16
EP0966463A1 (en) 1999-12-29
AU6825198A (en) 1998-09-22
CO4940415A1 (en) 2000-07-24
PE51399A1 (en) 1999-06-07
IS5166A (en) 1999-08-27
NZ337315A (en) 2001-02-23
KR20000075907A (en) 2000-12-26
YU43499A (en) 2000-12-28
ID24207A (en) 2000-07-13
TR199902117T2 (en) 2000-03-21
BR9808305A (en) 2000-05-16
OA11154A (en) 2003-04-16
PL335652A1 (en) 2000-05-08
NO994303L (en) 1999-11-03
HRP980114A2 (en) 1998-12-31
ZA981791B (en) 1999-09-03
EE9900387A (en) 2000-04-17
BG103779A (en) 2000-06-30
CA2282851A1 (en) 1998-09-11
AP9901637A0 (en) 1999-09-30
GB9704498D0 (en) 1997-04-23
EA199900710A1 (en) 2000-04-24
WO1998039327A1 (en) 1998-09-11
NO994303D0 (en) 1999-09-03
HUP0002109A2 (en) 2001-04-28
JP2001513796A (en) 2001-09-04
CN1249750A (en) 2000-04-05
IL131489A0 (en) 2001-01-28

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