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EE200000290A - Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks - Google Patents

Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks

Info

Publication number
EE200000290A
EE200000290A EEP200000290A EEP200000290A EE200000290A EE 200000290 A EE200000290 A EE 200000290A EE P200000290 A EEP200000290 A EE P200000290A EE P200000290 A EEP200000290 A EE P200000290A EE 200000290 A EE200000290 A EE 200000290A
Authority
EE
Estonia
Prior art keywords
tetrahydropyridines
alzheimer
namely
treatment
combination
Prior art date
Application number
EEP200000290A
Other languages
English (en)
Inventor
Maffrand Jean-Pierre
Soubrie Philippe
Terranova Jean-Paul
Original Assignee
Sanofi-Synthlabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9714322A external-priority patent/FR2771007B1/fr
Priority claimed from FR9714324A external-priority patent/FR2771006B1/fr
Application filed by Sanofi-Synthlabo filed Critical Sanofi-Synthlabo
Publication of EE200000290A publication Critical patent/EE200000290A/et
Publication of EE04235B1 publication Critical patent/EE04235B1/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EEP200000290A 1997-11-14 1998-11-09 Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks EE04235B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9714322A FR2771007B1 (fr) 1997-11-14 1997-11-14 Association de principes actifs pour le traitement de la demence senile du type alzheimer
FR9714324A FR2771006B1 (fr) 1997-11-14 1997-11-14 Association de principes actifs pour le traitement de la demence senile du type alzheimer
PCT/FR1998/002384 WO1999025363A1 (fr) 1997-11-14 1998-11-09 Association de principes actifs, notamment de tetrahydropyridines et d'agents inhibiteurs de l'acetylcholinesterase, pour le traitement de la demence senile du type alzheimer

Publications (2)

Publication Number Publication Date
EE200000290A true EE200000290A (et) 2001-06-15
EE04235B1 EE04235B1 (et) 2004-02-16

Family

ID=26233932

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000290A EE04235B1 (et) 1997-11-14 1998-11-09 Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks

Country Status (27)

Country Link
EP (1) EP1030671A1 (et)
JP (1) JP2001523642A (et)
KR (1) KR100599350B1 (et)
CN (1) CN1243540C (et)
AU (1) AU743228B2 (et)
BG (1) BG64819B1 (et)
BR (1) BR9814035A (et)
CA (1) CA2309966A1 (et)
CO (1) CO4980891A1 (et)
DZ (1) DZ2649A1 (et)
EA (1) EA003255B1 (et)
EE (1) EE04235B1 (et)
HU (1) HUP0100098A3 (et)
ID (1) ID24933A (et)
IL (2) IL136122A0 (et)
IS (1) IS5482A (et)
MY (1) MY120461A (et)
NO (1) NO20002450L (et)
NZ (1) NZ504420A (et)
OA (1) OA11464A (et)
PL (1) PL194597B1 (et)
SA (1) SA98190747B1 (et)
SK (1) SK286040B6 (et)
TR (1) TR200001262T2 (et)
TW (1) TW585766B (et)
UY (1) UY25247A1 (et)
WO (1) WO1999025363A1 (et)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2389937T (pt) * 2002-06-14 2018-10-26 Toyama Chemical Co Ltd Composição farmacêutica para melhorar as funções cerebrais
US20060160079A1 (en) * 2002-08-07 2006-07-20 Lane Roger M Methods for the treatment of dementia based on apo e genotype
CN1520818A (zh) * 2003-02-09 2004-08-18 山东绿叶天然药物研究开发有限公司 治疗老年性痴呆的胆碱酯酶抑制剂药物组合物
NZ555693A (en) 2004-12-27 2010-10-29 Eisai R&D Man Co Ltd Matrix type sustained-release preparation containing donepezil
WO2015116923A1 (en) 2014-01-31 2015-08-06 Cognition Therapeutics, Inc. Isoindoline compositions and methods for treating neurodegenerative disease
CN110869011B (zh) * 2017-05-15 2024-01-05 考格尼申治疗股份有限公司 用于治疗神经退行性疾病的组合物
KR102224917B1 (ko) 2018-03-20 2021-03-09 (주)인벤티지랩 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물의 제조 방법 및 이의 제조 방법으로 제조된 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물
WO2019182319A1 (ko) * 2018-03-20 2019-09-26 (주)인벤티지랩 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물의 제조 방법 및 이의 제조 방법으로 제조된 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물
CN109265391B (zh) * 2018-11-13 2021-11-19 枣庄学院 联苯多取代1,2,5,6-四氢吡啶化合物及其合成方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
US5453428A (en) * 1991-02-14 1995-09-26 The Mount Sinai School Of Medicine Of The City Of New York Method and composition for the treatment of apathy-amotivation syndrome
EP0813416B1 (en) * 1995-03-06 2005-05-25 Interneuron Pharmaceuticals Incorporated Reduction of infarct volume using citicoline
FR2736053B1 (fr) * 1995-06-28 1997-09-19 Sanofi Sa Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines

Also Published As

Publication number Publication date
WO1999025363A1 (fr) 1999-05-27
CN1243540C (zh) 2006-03-01
KR100599350B1 (ko) 2006-07-12
JP2001523642A (ja) 2001-11-27
EA003255B1 (ru) 2003-02-27
BG64819B1 (bg) 2006-05-31
PL194597B1 (pl) 2007-06-29
CO4980891A1 (es) 2000-11-27
SK7112000A3 (en) 2000-10-09
DZ2649A1 (fr) 2004-12-28
NO20002450D0 (no) 2000-05-11
NZ504420A (en) 2003-08-29
TW585766B (en) 2004-05-01
IL136122A0 (en) 2001-05-20
SK286040B6 (sk) 2008-01-07
AU743228B2 (en) 2002-01-24
EP1030671A1 (fr) 2000-08-30
EE04235B1 (et) 2004-02-16
TR200001262T2 (tr) 2001-01-22
PL340500A1 (en) 2001-02-12
SA98190747B1 (ar) 2006-11-04
EA200000412A1 (ru) 2000-12-25
HUP0100098A3 (en) 2001-12-28
AU1160999A (en) 1999-06-07
HUP0100098A2 (hu) 2001-07-30
IS5482A (is) 2000-05-09
IL136122A (en) 2006-07-05
BG104428A (en) 2001-08-31
CN1285742A (zh) 2001-02-28
CA2309966A1 (en) 1999-05-27
OA11464A (en) 2003-11-18
KR20010032099A (ko) 2001-04-16
ID24933A (id) 2000-08-31
BR9814035A (pt) 2000-09-26
NO20002450L (no) 2000-07-14
UY25247A1 (es) 2001-05-31
MY120461A (en) 2005-10-31

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Legal Events

Date Code Title Description
HD1A Correction of address
HC1A Change of owner name
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20081109