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FR2771007B1 - Association de principes actifs pour le traitement de la demence senile du type alzheimer - Google Patents

Association de principes actifs pour le traitement de la demence senile du type alzheimer

Info

Publication number
FR2771007B1
FR2771007B1 FR9714322A FR9714322A FR2771007B1 FR 2771007 B1 FR2771007 B1 FR 2771007B1 FR 9714322 A FR9714322 A FR 9714322A FR 9714322 A FR9714322 A FR 9714322A FR 2771007 B1 FR2771007 B1 FR 2771007B1
Authority
FR
France
Prior art keywords
treatment
combination
active ingredients
senile dementia
alzheimer type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9714322A
Other languages
English (en)
Other versions
FR2771007A1 (fr
Inventor
Jean Pierre Maffrand
Philippe Soubrie
Jean Paul Terranova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR9714322A priority Critical patent/FR2771007B1/fr
Priority to CO98062479A priority patent/CO4980891A1/es
Priority to TW087117874A priority patent/TW585766B/zh
Priority to JP2000520796A priority patent/JP2001523642A/ja
Priority to AU11609/99A priority patent/AU743228B2/en
Priority to CNB988130947A priority patent/CN1243540C/zh
Priority to EP98954538A priority patent/EP1030671A1/fr
Priority to IL13612298A priority patent/IL136122A0/xx
Priority to BR9814035-3A priority patent/BR9814035A/pt
Priority to IDW20000860A priority patent/ID24933A/id
Priority to EA200000412A priority patent/EA003255B1/ru
Priority to PCT/FR1998/002384 priority patent/WO1999025363A1/fr
Priority to NZ504420A priority patent/NZ504420A/en
Priority to HU0100098A priority patent/HUP0100098A3/hu
Priority to CA002309966A priority patent/CA2309966A1/fr
Priority to PL98340500A priority patent/PL194597B1/pl
Priority to TR2000/01262T priority patent/TR200001262T2/xx
Priority to KR1020007005231A priority patent/KR100599350B1/ko
Priority to ARP980105661A priority patent/AR013750A1/es
Priority to SK711-2000A priority patent/SK286040B6/sk
Priority to EEP200000290A priority patent/EE04235B1/xx
Priority to GT199800181A priority patent/GT199800181A/es
Priority to DZ980259A priority patent/DZ2649A1/fr
Priority to UY25247A priority patent/UY25247A1/es
Priority to MYPI98005180A priority patent/MY120461A/en
Priority to SA98190747A priority patent/SA98190747B1/ar
Publication of FR2771007A1 publication Critical patent/FR2771007A1/fr
Priority to IS5482A priority patent/IS5482A/is
Priority to NO20002450A priority patent/NO20002450L/no
Priority to BG104428A priority patent/BG64819B1/bg
Priority to OA1200000141A priority patent/OA11464A/en
Priority to IL136122A priority patent/IL136122A/en
Application granted granted Critical
Publication of FR2771007B1 publication Critical patent/FR2771007B1/fr
Priority to US10/268,378 priority patent/US20030092737A1/en
Priority to US11/070,351 priority patent/US20050148614A1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR9714322A 1997-11-14 1997-11-14 Association de principes actifs pour le traitement de la demence senile du type alzheimer Expired - Fee Related FR2771007B1 (fr)

Priority Applications (33)

Application Number Priority Date Filing Date Title
FR9714322A FR2771007B1 (fr) 1997-11-14 1997-11-14 Association de principes actifs pour le traitement de la demence senile du type alzheimer
CO98062479A CO4980891A1 (es) 1997-11-14 1998-10-26 Asociacion de principios activos para el tratamiento de la demencia senil de tipo azheimer
TW087117874A TW585766B (en) 1997-11-14 1998-10-28 Combination of active ingredients for the treatment of senile dementia of the Alzheimer type
EEP200000290A EE04235B1 (et) 1997-11-14 1998-11-09 Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks
CNB988130947A CN1243540C (zh) 1997-11-14 1998-11-09 用于治疗阿尔茨海默氏型老年性痴呆的活性组分的组合
EP98954538A EP1030671A1 (fr) 1997-11-14 1998-11-09 Association de principes actifs, notamment de tetrahydropyridines et d'agents inhibiteurs de l'acetylcholinesterase, pour le traitement de la demence senile du type alzheimer
IL13612298A IL136122A0 (en) 1997-11-14 1998-11-09 Combination of active principles, in particular of tetrahydropyridines and acetylcholinesterase inhibiting agents, for treating senile dementia such as alzheimer dementia
BR9814035-3A BR9814035A (pt) 1997-11-14 1998-11-09 Associação de princìpios ativos, notadamente de tetra-hidropiridinas e de agentes inibidores da acetilcolinesterase, para o tratamento da demência senil do tipo alzheimer.
IDW20000860A ID24933A (id) 1997-11-14 1998-11-09 Kombinasi komponen aktif untuk perawatan senile dementia dari jenis alzheimer
EA200000412A EA003255B1 (ru) 1997-11-14 1998-11-09 Комбинация производных тетрагидропиридинов и ингибиторов ацетилхолинэстеразы для лечения старческой деменции по типу альцгеймера
PCT/FR1998/002384 WO1999025363A1 (fr) 1997-11-14 1998-11-09 Association de principes actifs, notamment de tetrahydropyridines et d'agents inhibiteurs de l'acetylcholinesterase, pour le traitement de la demence senile du type alzheimer
NZ504420A NZ504420A (en) 1997-11-14 1998-11-09 Combination of tetrahydropyridins and acetylcholinesterase inhibiting agents, for treating senile dementia such as alzheimer dementia
HU0100098A HUP0100098A3 (en) 1997-11-14 1998-11-09 Pharmaceutical combination of active princeples, in particular of tetrahydropyridins and acetylcholinesterase inhibiting agents, for treating senile dementia such as alzheimer dementia
CA002309966A CA2309966A1 (fr) 1997-11-14 1998-11-09 Association de principes actifs, notamment de tetrahydropyridines et d'agents inhibiteurs de l'acetylcholinesterase, pour le traitement de la demence senile du type alzheimer
PL98340500A PL194597B1 (pl) 1997-11-14 1998-11-09 Kompozycja farmaceutyczna zawierająca pochodną tetrahydropirydyny i środki inhibitujące acetylocholinoesterazy i jej zastosowanie
TR2000/01262T TR200001262T2 (tr) 1997-11-14 1998-11-09 Alzheimer tipi yaşlılık demansının tedavisi için aktif muhteviyatların kombinasyonu
JP2000520796A JP2001523642A (ja) 1997-11-14 1998-11-09 アルツハイマー型痴呆のような老人性痴呆を治療するための活性成分、特にテトラヒドロピリジン類とアセチルコリンエステラーゼ阻害剤との組み合わせ
ARP980105661A AR013750A1 (es) 1997-11-14 1998-11-09 Asociacion de principios activos para el tratamiento de la demencia senil de tipo alzheimer
SK711-2000A SK286040B6 (sk) 1997-11-14 1998-11-09 Farmaceutická kompozícia obsahujúca 1-(2-naft-2-yletyl)-4-(3- trifluórmetylfenyl)-1,2,3,6-tetrahydropyridín hydrochlorid a donepezil alebo takrín
AU11609/99A AU743228B2 (en) 1997-11-14 1998-11-09 Combination of active principles, in particular of tetrahydropyridins and acetylcholinesterase inhibiting agents, for treating senile dementia such as Alzheimer dementia
KR1020007005231A KR100599350B1 (ko) 1997-11-14 1998-11-09 알츠하이머 치매와 같은 노인성 치매 치료용의 활성 성분들, 특히, 테트라히드로피리딘류 및 아세틸콜린에스테라아제 억제제의 배합물
GT199800181A GT199800181A (es) 1997-11-14 1998-11-10 Asociacion de principios activos para el tratamiento de la demencia senil de tipo alzheimer.
DZ980259A DZ2649A1 (fr) 1997-11-14 1998-11-11 Association des principes actifs pour le traitement de la démence sénile du type alzheimer.
UY25247A UY25247A1 (es) 1997-11-14 1998-11-12 Asociacion de principios activos para el tratamiento de la demencia senil de tipo alzheimer
MYPI98005180A MY120461A (en) 1997-11-14 1998-11-14 Combination of active principles, in particular of tetrahydropyridins and acetylcholinesterase inhibiting agents, for treating senile dementia.
SA98190747A SA98190747B1 (ar) 1997-11-14 1998-11-14 توليفة من عوامل فعالة وبصفة خاصة tetrahydropyridine وعوامل مثبطة لانزيم acetylcholinesterase لعلاج عته الشيخويخة مثل عته الزهايمر alzheimer
IS5482A IS5482A (is) 1997-11-14 2000-05-09 Samsetning af virkum efnisþáttum sérstaklega af tetrahýdrópýridínum og asetýlkólín esterasa hindrandi miðlun til meðhöndlunar á elliglöpum á borð viðAlzheimers vitglöp
BG104428A BG64819B1 (bg) 1997-11-14 2000-05-11 Комбиниране на тетрахидропиридини и средства, инхибиращи ацетилхолинестераза, за лечение на сенилнадеменция от алцхаймеров тип
NO20002450A NO20002450L (no) 1997-11-14 2000-05-11 Sammenstilling av aktive bestanddeler, særlig tetrahydropyridiner og acetylcholinesterase-inhiberende midler, for behandling av senil demens av Alzheimer-type
OA1200000141A OA11464A (en) 1997-11-14 2000-05-12 Combination of active principles, in particular oftetrahydropyridins and acetylcholinesterase inhib iting agents, for treating senile dementia such asAlzheimer dementia.
IL136122A IL136122A (en) 1997-11-14 2000-05-14 Compounds of active ingredients, especially inhibitors of tetrahydropyridines and acetylcholinesterase carriers, for the treatment of dementia in adults, such as Alzheimer's dementia
US10/268,378 US20030092737A1 (en) 1997-11-14 2002-10-10 Combination of active ingredients for the treatment of senile dementia of the Alzheimer type
US11/070,351 US20050148614A1 (en) 1997-11-14 2005-03-02 Combination of active ingredients for the treatment of senile dementia of the Alzheimer type

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9714322A FR2771007B1 (fr) 1997-11-14 1997-11-14 Association de principes actifs pour le traitement de la demence senile du type alzheimer

Publications (2)

Publication Number Publication Date
FR2771007A1 FR2771007A1 (fr) 1999-05-21
FR2771007B1 true FR2771007B1 (fr) 2000-12-01

Family

ID=9513397

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9714322A Expired - Fee Related FR2771007B1 (fr) 1997-11-14 1997-11-14 Association de principes actifs pour le traitement de la demence senile du type alzheimer

Country Status (3)

Country Link
AR (1) AR013750A1 (fr)
FR (1) FR2771007B1 (fr)
GT (1) GT199800181A (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
US5453428A (en) * 1991-02-14 1995-09-26 The Mount Sinai School Of Medicine Of The City Of New York Method and composition for the treatment of apathy-amotivation syndrome
FR2736053B1 (fr) * 1995-06-28 1997-09-19 Sanofi Sa Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines

Also Published As

Publication number Publication date
GT199800181A (es) 2000-05-03
AR013750A1 (es) 2001-01-10
FR2771007A1 (fr) 1999-05-21

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Legal Events

Date Code Title Description
TP Transmission of property
CD Change of name or company name
ST Notification of lapse

Effective date: 20090731