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EE05178B1 - 1,3-dioksolaanid, nende saamine ja kasutamine k”havastaste ravimite valmistamiseks ning neid sisaldavad farmatseutilised kompositsioonid - Google Patents

1,3-dioksolaanid, nende saamine ja kasutamine k”havastaste ravimite valmistamiseks ning neid sisaldavad farmatseutilised kompositsioonid

Info

Publication number
EE05178B1
EE05178B1 EEP200300036A EEP200300036A EE05178B1 EE 05178 B1 EE05178 B1 EE 05178B1 EE P200300036 A EEP200300036 A EE P200300036A EE P200300036 A EEP200300036 A EE P200300036A EE 05178 B1 EE05178 B1 EE 05178B1
Authority
EE
Estonia
Prior art keywords
preparation
dioxolanes
pharmaceuticals
pharmaceutical compositions
compositions containing
Prior art date
Application number
EEP200300036A
Other languages
English (en)
Inventor
Allegretti Marcello
Candida Cesta Maria
Curti Roberto
Pellegrini Luigi
Melillo Gabriella
Original Assignee
Domp S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Domp S.P.A. filed Critical Domp S.P.A.
Publication of EE200300036A publication Critical patent/EE200300036A/et
Publication of EE05178B1 publication Critical patent/EE05178B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glass Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
EEP200300036A 2000-07-28 2001-07-18 1,3-dioksolaanid, nende saamine ja kasutamine k”havastaste ravimite valmistamiseks ning neid sisaldavad farmatseutilised kompositsioonid EE05178B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI001734A IT1318650B1 (it) 2000-07-28 2000-07-28 1,3-diossolani ad attivita' antitosse.
PCT/EP2001/008304 WO2002010149A1 (en) 2000-07-28 2001-07-18 1,3-dioxolanes with antitussive activity

Publications (2)

Publication Number Publication Date
EE200300036A EE200300036A (et) 2004-10-15
EE05178B1 true EE05178B1 (et) 2009-06-15

Family

ID=11445591

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300036A EE05178B1 (et) 2000-07-28 2001-07-18 1,3-dioksolaanid, nende saamine ja kasutamine k”havastaste ravimite valmistamiseks ning neid sisaldavad farmatseutilised kompositsioonid

Country Status (27)

Country Link
US (1) US6835734B2 (et)
EP (1) EP1307441B1 (et)
JP (1) JP5107497B2 (et)
KR (1) KR100781403B1 (et)
CN (1) CN1204135C (et)
AT (1) ATE266018T1 (et)
AU (1) AU2001287638A1 (et)
BR (1) BR0112765A (et)
CZ (1) CZ301087B6 (et)
DE (1) DE60103164T2 (et)
DK (1) DK1307441T3 (et)
EE (1) EE05178B1 (et)
ES (1) ES2219562T3 (et)
HK (1) HK1058797A1 (et)
HU (1) HUP0301497A3 (et)
IL (2) IL153515A0 (et)
IT (1) IT1318650B1 (et)
MX (1) MXPA02012920A (et)
PL (1) PL206307B1 (et)
PT (1) PT1307441E (et)
RS (1) RS50861B (et)
RU (1) RU2276149C2 (et)
SI (1) SI21040A (et)
SK (1) SK286794B6 (et)
TR (1) TR200401315T4 (et)
UA (1) UA73789C2 (et)
WO (1) WO2002010149A1 (et)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318651B1 (it) * 2000-07-28 2003-08-27 Dompe Spa Sintesi di (+-)1,3-diossolani e loro risoluzione ottica.
TWI496776B (zh) * 2007-11-15 2015-08-21 Astrazeneca Ab 製備(3aR,4S,6R,6aS)-6-胺基-2,2-二甲基四氫-3aH-環戊并[d][1,3]二氧雜環戊烯-4-醇之純非對映異構性之二苯甲醯-L-酒石酸鹽之方法
EP2070915A1 (en) * 2007-12-03 2009-06-17 A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. New process for the synthesis of moguisteine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049660A (en) * 1971-06-18 1977-09-20 Delalande S.A. N-substituted derivatives of 4 (N-piperazinylmethyl) spiro dibenzocycloheptadi- (or tri-) ene-5, 2-dioxolane (1,3) their method of preparation and their application in therapeutics
IT1203721B (it) * 1983-12-29 1989-02-23 Dompe Farmaceutici Spa Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono
NL8801622A (nl) * 1988-06-25 1990-01-16 Stamicarbon Bereiding van enantiomeren van dropropizine.
IT1226570B (it) * 1988-08-01 1991-01-24 Bidachem Spa Procedimento di preparazione della levo- e destro-dropropizina
IT1254452B (it) * 1992-02-14 1995-09-25 Dompe Farmaceutici Spa N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli
IT1254993B (it) * 1992-06-24 1995-10-11 Procedimento per la preparazione degli enantiomeri della dropropizina
IL111730A (en) * 1993-11-29 1998-12-06 Fujisawa Pharmaceutical Co Piperazine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
IT1318651B1 (it) * 2000-07-28 2003-08-27 Dompe Spa Sintesi di (+-)1,3-diossolani e loro risoluzione ottica.

Also Published As

Publication number Publication date
JP2004505073A (ja) 2004-02-19
ES2219562T3 (es) 2004-12-01
MXPA02012920A (es) 2004-04-20
KR20030016425A (ko) 2003-02-26
US20040038989A1 (en) 2004-02-26
DE60103164T2 (de) 2005-05-04
HUP0301497A3 (en) 2005-08-29
PL206307B1 (pl) 2010-07-30
AU2001287638A1 (en) 2002-02-13
ATE266018T1 (de) 2004-05-15
PL361172A1 (en) 2004-09-20
IL153515A (en) 2006-12-10
CN1204135C (zh) 2005-06-01
ITMI20001734A0 (it) 2000-07-28
US6835734B2 (en) 2004-12-28
KR100781403B1 (ko) 2007-12-03
CZ2003268A3 (cs) 2003-06-18
HK1058797A1 (en) 2004-06-04
JP5107497B2 (ja) 2012-12-26
DE60103164D1 (de) 2004-06-09
EP1307441B1 (en) 2004-05-06
RS50861B (sr) 2010-08-31
ITMI20001734A1 (it) 2002-01-28
HUP0301497A2 (hu) 2003-09-29
DK1307441T3 (da) 2004-08-09
SI21040A (sl) 2003-04-30
BR0112765A (pt) 2004-01-13
EP1307441A1 (en) 2003-05-07
RU2276149C2 (ru) 2006-05-10
PT1307441E (pt) 2004-09-30
CZ301087B6 (cs) 2009-11-04
EE200300036A (et) 2004-10-15
WO2002010149A1 (en) 2002-02-07
CN1444578A (zh) 2003-09-24
TR200401315T4 (tr) 2004-07-21
IT1318650B1 (it) 2003-08-27
IL153515A0 (en) 2003-07-06
YU3003A (sh) 2006-05-25
UA73789C2 (en) 2005-09-15
SK892003A3 (en) 2003-09-11
SK286794B6 (sk) 2009-05-07

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Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20120718