[go: up one dir, main page]

ECSP077247A - Trans - clomifeno para el tratamiento de la hipertrofia prostatica benigna, cancer prostatico, hipogonodismo, trigliceridos elevados y alto colesterol - Google Patents

Trans - clomifeno para el tratamiento de la hipertrofia prostatica benigna, cancer prostatico, hipogonodismo, trigliceridos elevados y alto colesterol

Info

Publication number
ECSP077247A
ECSP077247A EC2007007247A ECSP077247A ECSP077247A EC SP077247 A ECSP077247 A EC SP077247A EC 2007007247 A EC2007007247 A EC 2007007247A EC SP077247 A ECSP077247 A EC SP077247A EC SP077247 A ECSP077247 A EC SP077247A
Authority
EC
Ecuador
Prior art keywords
trans
treatment
triglicerids
hypogonodism
clomphene
Prior art date
Application number
EC2007007247A
Other languages
English (en)
Inventor
Joseph Podolski
Ronald Wiehle
Original Assignee
Repros Therapeutis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Repros Therapeutis Inc filed Critical Repros Therapeutis Inc
Publication of ECSP077247A publication Critical patent/ECSP077247A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Composiciones que comprenden trans-clomifeno pueden ser útiles en el tratamiento de hipertrofia benigna de la próstata, cáncer de próstata, niveles elevados de triglicéridos e hipogonadismo
EC2007007247A 2004-07-14 2007-02-14 Trans - clomifeno para el tratamiento de la hipertrofia prostatica benigna, cancer prostatico, hipogonodismo, trigliceridos elevados y alto colesterol ECSP077247A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58822304P 2004-07-14 2004-07-14
US58813004P 2004-07-14 2004-07-14
US58812304P 2004-07-14 2004-07-14

Publications (1)

Publication Number Publication Date
ECSP077247A true ECSP077247A (es) 2007-03-29

Family

ID=35134086

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2007007247A ECSP077247A (es) 2004-07-14 2007-02-14 Trans - clomifeno para el tratamiento de la hipertrofia prostatica benigna, cancer prostatico, hipogonodismo, trigliceridos elevados y alto colesterol

Country Status (6)

Country Link
US (1) US20080242726A1 (es)
EP (1) EP1776098A1 (es)
BR (1) BRPI0513129A (es)
EC (1) ECSP077247A (es)
MX (1) MX2007000050A (es)
WO (1) WO2006019916A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7737185B2 (en) 2001-07-09 2010-06-15 Repros Therapeutics Inc. Methods and compositions with trans-clomiphene
CN1954807A (zh) 2001-07-09 2007-05-02 佐纳根有限公司 富含反式克罗米酚的克罗米酚组合物
BRPI0609389A2 (pt) * 2005-03-22 2010-03-30 Repros Therapeutics Inc tablete, composição e respectivos usos
NZ591955A (en) 2007-10-16 2011-10-28 Repros Therapeutics Inc Trans-clomiphene for diabetes mellitus type 2
UA113291C2 (xx) 2011-08-04 2017-01-10 Метаболіти транскломіфену і їх застосування
EP2887922A1 (en) 2012-08-21 2015-07-01 Repros Therapeutics Inc. Trans-clomiphene formulations and uses thereof
US9687458B2 (en) 2012-11-02 2017-06-27 Repros Therapeutics Inc. Trans-clomiphene for use in cancer therapy
US20160051495A1 (en) * 2014-08-20 2016-02-25 Professional Compounding Centers Of America Oral Transmucosal Compositions including C-SERMs for Low Testosterone Levels in Men
CN108883083A (zh) * 2016-02-25 2018-11-23 艾森潘帕克制药股份有限公司 两种氯米芬异构体的口服剂型及使用其治疗继发性腺功能减退症的方法
CN108420806A (zh) * 2017-02-15 2018-08-21 武汉华杰世纪生物医药有限公司 具有靶向性的抗肿瘤药物

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4061733A (en) * 1976-10-15 1977-12-06 Narayan Vishwanath Gunjikar Veterinary compositions for inducing estrus in animals and method
US4729999A (en) * 1984-10-12 1988-03-08 Bcm Technologies Antiestrogen therapy for symptoms of estrogen deficiency
US4820736A (en) * 1987-03-20 1989-04-11 Yale University Use of clomiphene to predict fertility in a human female
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5776923A (en) * 1993-01-19 1998-07-07 Endorecherche, Inc. Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
DE4435368A1 (de) * 1994-09-22 1996-03-28 Schering Ag Verwendung von Aromatasehemmern zur Herstellung eines Arzneimittels zur Behandlung eines relativen Androgenmangels beim Mann
US6221399B1 (en) * 1995-08-17 2001-04-24 Csir Method of making controlled release particles of complexed polymers
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
IL120262A (en) * 1996-02-28 2001-01-28 Pfizer Droloxifene and derivatives thereof for use in increasing serum testosterone levels
PL191399B1 (pl) * 1996-10-28 2006-05-31 Gen Mills Inc Sposób kapsułkowania lub osadzania składnika w osnowie w procesie ciągłym, sposób kapsułkowania i/lub osadzania składników w osnowie opartej na węglowodanach, sposób kapsułkowania i/lub osadzania składników w osnowie oraz kapsułka
NZ500649A (en) * 1997-04-03 2001-05-25 Guilford Pharm Inc Biodegradable terephthalate polyester-poly(phosphate) polymers, compositions, articles, and methods for making a biosorbable suture, an orthopedic appliance or bone cement for repairing injuries to bone or connective tissue
US6653297B1 (en) * 1997-07-03 2003-11-25 Medical College Of Hampton Roads Control of selective estrogen receptor modulators
US6342250B1 (en) * 1997-09-25 2002-01-29 Gel-Del Technologies, Inc. Drug delivery devices comprising biodegradable protein for the controlled release of pharmacologically active agents and method of making the drug delivery devices
US6413533B1 (en) * 1998-05-07 2002-07-02 The University Of Tennessee Research Corporation Method for chemoprevention of prostate cancer
DE69935335T2 (de) * 1998-08-07 2007-11-22 Novartis Vaccines and Diagnostics, Inc., Emeryville Pyrazole als modulatoren des östrogenrezeptors
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
CO5180583A1 (es) * 1999-06-11 2002-07-30 Watson Pharmaceuticals Inc Administracion de esteroides androgenicos no orales a las mujeres
AU6132700A (en) * 1999-09-30 2001-04-05 Chienna B.V. Polymers loaded with bioactive agents
AU3104301A (en) * 2000-01-20 2001-07-31 Noven Pharmaceuticals, Inc. Compositions and methods to effect the release profile in the transdermal administration of active agents
EP1289519B1 (en) * 2000-05-26 2019-02-13 Harry Fisch Methods of treating androgen deficiency in men using clomiphene
US7067557B2 (en) * 2000-05-26 2006-06-27 Harry Fisch Methods of treating androgen deficiency in men using selective antiestrogens
EP1303674B1 (de) * 2000-07-22 2006-03-15 Hubertus Greschbach Modul zum aufbau von plattformen
US6503894B1 (en) * 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US6743448B2 (en) * 2000-12-11 2004-06-01 Abraham H. Kryger Topical testosterone formulations and associated methods
CN1954807A (zh) * 2001-07-09 2007-05-02 佐纳根有限公司 富含反式克罗米酚的克罗米酚组合物
US7173064B2 (en) * 2001-07-09 2007-02-06 Repros Therapeutics Inc. Methods and compositions with trans-clomiphene for treating wasting and lipodystrophy
US6645974B2 (en) * 2001-07-31 2003-11-11 Merck & Co., Inc. Androgen receptor modulators and methods for use thereof
US20060269611A1 (en) * 2001-11-29 2006-11-30 Steiner Mitchell S Prevention and treatment of androgen-deprivation induced osteoporosis
US7105679B2 (en) * 2001-12-19 2006-09-12 Kanojia Ramesh M Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators

Also Published As

Publication number Publication date
US20080242726A1 (en) 2008-10-02
EP1776098A1 (en) 2007-04-25
BRPI0513129A (pt) 2008-04-29
WO2006019916A1 (en) 2006-02-23
MX2007000050A (es) 2007-07-10

Similar Documents

Publication Publication Date Title
ECSP077247A (es) Trans - clomifeno para el tratamiento de la hipertrofia prostatica benigna, cancer prostatico, hipogonodismo, trigliceridos elevados y alto colesterol
AR054667A1 (es) Composicion hemostatica que comprende acido hialuronico
WO2007061874A3 (en) Methods and compositions for use in treating cancer
CL2012002844A1 (es) Compuestos derivados de cromen-2-ona; composicion farmaceutica que los comprende; y su uso en el tratamiento de un trastorno proliferativo de celulas tal como cancer (divisional solicitud nº 311-07).
GEP20074122B (en) Treating benign prostate hyperplasia with selective androgen receptor modulators
CO6311078A2 (es) Compuestos heterociclicos que contienen dos o más heteroanillos, que contienen átomos de nitrogeno como únicos heteroátomos en el anillo, en donde al menos un anillo es de 6 miembros con un átomo de nitrógeno, que contienen tres ó más heteroátomos, c
CY1113137T1 (el) Παραγωγα πυριμιδινυλ-πυριδαζινονης
WO2004034990A3 (en) Methods and compositions for use in treating cancer
SV2009003227A (es) Composiciones de inhibidores de chk 1 ref. x-17672
WO2007051065A3 (en) Compositions and treatments for inhibiting kinase and/or hmg-coa reductase
CL2012000623A1 (es) Compuestos derivados de 4-[4,4-dimetil-5oxo-3-(piridin-ilmetil)-2-tioxoimidazolidin-1-il]-2-(trifluorometil)benzonitrilo, con propiedades antiandrogenicas; metodo de preparacion; composcion farmaceutica; y su uso para el tratamiento y/o profilaxis de cancer de prostata.
CL2007002953A1 (es) Compuestos derivados de espiro-oxindol; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento del dolor, cancer, prurito, hiperplasia prostatica benigna, hipercolesterolemia.
TW200715634A (en) Stable organic devices
AR059203A1 (es) Composiciones para uso vaginal
UY32769A (es) Composición para el tratamiento de la hiperplasia prostática benigna
MX2008002057A (es) Complejo de inclusion del inhibidor del factor xa con ciclodextrina.
EA201071248A1 (ru) Дизамещенные фталазиновые антагонисты пути hedgehog
NZ579478A (en) Epha3 antibodies for the treatment of solid tumors
WO2002030465A3 (en) Compositions that inhibit proliferation of cancer cells
ATE510553T1 (de) Beta-2-glycoprotein 1 als angiogenesehemmer
WO2004064736A3 (en) Treatment of benign prostatic hyperplasia using energolytic agents
NI200700080A (es) Compuesto de 4-amino-sustituido-2-sustitiuido-1,2,3,4-tetrahidroquinolina.
BRPI0821025A2 (pt) Método para tratar biomassa, método para produzir biotanol, uso da composição e biomassa processada.
BRPI0507998A (pt) uso de um inibidor de serina palmitoiltransferase (spt) para tratar aterosclerose e dislipidemia
WO2007123579A3 (en) Translational dysfunction based therapeutics