MX2007000050A - Trans-clomifeno para el tratamiento de hipertrofia de prostata benigna, cancer de prostata, hipogonadismo, trigliceridos elevados y colesterol elevado. - Google Patents
Trans-clomifeno para el tratamiento de hipertrofia de prostata benigna, cancer de prostata, hipogonadismo, trigliceridos elevados y colesterol elevado.Info
- Publication number
- MX2007000050A MX2007000050A MX2007000050A MX2007000050A MX2007000050A MX 2007000050 A MX2007000050 A MX 2007000050A MX 2007000050 A MX2007000050 A MX 2007000050A MX 2007000050 A MX2007000050 A MX 2007000050A MX 2007000050 A MX2007000050 A MX 2007000050A
- Authority
- MX
- Mexico
- Prior art keywords
- clomiphene
- hypogonadism
- trans
- treatment
- high cholesterol
- Prior art date
Links
- 206010014486 Elevated triglycerides Diseases 0.000 title abstract 2
- 206010020880 Hypertrophy Diseases 0.000 title abstract 2
- 206010058359 Hypogonadism Diseases 0.000 title abstract 2
- 206010060862 Prostate cancer Diseases 0.000 title abstract 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 title abstract 2
- 210000002307 prostate Anatomy 0.000 title abstract 2
- GKIRPKYJQBWNGO-QPLCGJKRSA-N zuclomifene Chemical compound C1=CC(OCCN(CC)CC)=CC=C1C(\C=1C=CC=CC=1)=C(/Cl)C1=CC=CC=C1 GKIRPKYJQBWNGO-QPLCGJKRSA-N 0.000 title abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 2
- 235000012000 cholesterol Nutrition 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Las composiciarLes qe corroreodeo traris-ciorrifeno se pueder. criZizar para tratar hicertrofia de prostata becigca, cincer de prostata, civeZes eevadrs de trigiirerioo e cipcpooadisoo.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58813004P | 2004-07-14 | 2004-07-14 | |
US58822304P | 2004-07-14 | 2004-07-14 | |
US58812304P | 2004-07-14 | 2004-07-14 | |
PCT/US2005/025000 WO2006019916A1 (en) | 2004-07-14 | 2005-07-14 | Trans-clomiphene for the treatment of benign prostate hypertrophy, prostate cancer, hypogonadism, elevated triglycerides and high cholesterol |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2007000050A true MX2007000050A (es) | 2007-07-10 |
Family
ID=35134086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2007000050A MX2007000050A (es) | 2004-07-14 | 2005-07-14 | Trans-clomifeno para el tratamiento de hipertrofia de prostata benigna, cancer de prostata, hipogonadismo, trigliceridos elevados y colesterol elevado. |
Country Status (6)
Country | Link |
---|---|
US (1) | US20080242726A1 (es) |
EP (1) | EP1776098A1 (es) |
BR (1) | BRPI0513129A (es) |
EC (1) | ECSP077247A (es) |
MX (1) | MX2007000050A (es) |
WO (1) | WO2006019916A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE406153T1 (de) | 2001-07-09 | 2008-09-15 | Repros Therapeutics Inc | Verfahren und materialien für die behandlung des testosteron-mangels bei männern |
US7737185B2 (en) | 2001-07-09 | 2010-06-15 | Repros Therapeutics Inc. | Methods and compositions with trans-clomiphene |
AU2006227243B2 (en) | 2005-03-22 | 2011-10-27 | Allergan pharmaceuticals International Ltd. | Dosing regimes for trans-clomiphene |
CN101896174B (zh) | 2007-10-16 | 2012-10-31 | 利普生物药剂公司 | 用于治疗代谢综合征的珠氯米芬 |
UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
US20150202167A1 (en) | 2012-08-21 | 2015-07-23 | Repros Therapeutics Inc. | Trans-Clomiphene Formulations and Uses Thereof |
JP2015535283A (ja) * | 2012-11-02 | 2015-12-10 | レプロス セラピューティクス インコーポレイティド | 癌療法における使用のためのトランス−クロミフェン |
US20160051495A1 (en) * | 2014-08-20 | 2016-02-25 | Professional Compounding Centers Of America | Oral Transmucosal Compositions including C-SERMs for Low Testosterone Levels in Men |
KR20180112048A (ko) * | 2016-02-25 | 2018-10-11 | 아스펜 파크 파마슈티컬스 인코포레이티드 | 클로미펜 이성질체들의 경구 제형 및 이차 생식선 기능저하증 치료를 위하여 이들을 사용하는 방법 |
CN108420806A (zh) * | 2017-02-15 | 2018-08-21 | 武汉华杰世纪生物医药有限公司 | 具有靶向性的抗肿瘤药物 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4061733A (en) * | 1976-10-15 | 1977-12-06 | Narayan Vishwanath Gunjikar | Veterinary compositions for inducing estrus in animals and method |
US4729999A (en) * | 1984-10-12 | 1988-03-08 | Bcm Technologies | Antiestrogen therapy for symptoms of estrogen deficiency |
US4820736A (en) * | 1987-03-20 | 1989-04-11 | Yale University | Use of clomiphene to predict fertility in a human female |
US5681585A (en) * | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
US5580578A (en) * | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
US5776923A (en) * | 1993-01-19 | 1998-07-07 | Endorecherche, Inc. | Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone |
GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
DE4435368A1 (de) * | 1994-09-22 | 1996-03-28 | Schering Ag | Verwendung von Aromatasehemmern zur Herstellung eines Arzneimittels zur Behandlung eines relativen Androgenmangels beim Mann |
AU6824996A (en) * | 1995-08-17 | 1997-03-12 | Dyer, Alison Margaret | Controlled release products |
US5773031A (en) * | 1996-02-27 | 1998-06-30 | L. Perrigo Company | Acetaminophen sustained-release formulation |
IL120262A (en) * | 1996-02-28 | 2001-01-28 | Pfizer | Droloxifene and derivatives thereof for use in increasing serum testosterone levels |
EP0935523B1 (en) * | 1996-10-28 | 2004-09-29 | Inc. General Mills | Embedding and encapsulation of controlled release particles |
EP0973818B1 (en) * | 1997-04-03 | 2004-10-13 | Guilford Pharmaceuticals Inc. | Biodegradable terephthalate polyester-poly(phosphate) polymers, compositions, articles, and methods for making and using the same |
US6653297B1 (en) * | 1997-07-03 | 2003-11-25 | Medical College Of Hampton Roads | Control of selective estrogen receptor modulators |
US6342250B1 (en) * | 1997-09-25 | 2002-01-29 | Gel-Del Technologies, Inc. | Drug delivery devices comprising biodegradable protein for the controlled release of pharmacologically active agents and method of making the drug delivery devices |
US6413533B1 (en) * | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
JP2002522422A (ja) * | 1998-08-07 | 2002-07-23 | カイロン コーポレイション | エストロゲンレセプターモジュレーターとしてのピラゾール |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
BR0011740A (pt) * | 1999-06-11 | 2002-05-14 | Watson Pharmaceuticals Inc | Administração de esteróides androgênicos não-orais a mulheres |
AU6132700A (en) * | 1999-09-30 | 2001-04-05 | Chienna B.V. | Polymers loaded with bioactive agents |
WO2001052823A2 (en) * | 2000-01-20 | 2001-07-26 | Noven Pharmaceuticals, Inc. | Compositions to effect the release profile in the transdermal administration of drugs |
WO2001091744A1 (en) * | 2000-05-26 | 2001-12-06 | Harry Fisch | Methods of treating androgen deficiency in men using selective antiestrogens |
US7067557B2 (en) * | 2000-05-26 | 2006-06-27 | Harry Fisch | Methods of treating androgen deficiency in men using selective antiestrogens |
WO2002008546A1 (de) * | 2000-07-22 | 2002-01-31 | Hubertus Greschbach | Modul zum aufbau von plattformen |
US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
CA2431566A1 (en) * | 2000-12-11 | 2002-07-18 | Testocreme, Llc | Topical testosterone formulations and associated methods |
ATE406153T1 (de) * | 2001-07-09 | 2008-09-15 | Repros Therapeutics Inc | Verfahren und materialien für die behandlung des testosteron-mangels bei männern |
US7173064B2 (en) * | 2001-07-09 | 2007-02-06 | Repros Therapeutics Inc. | Methods and compositions with trans-clomiphene for treating wasting and lipodystrophy |
US6645974B2 (en) * | 2001-07-31 | 2003-11-11 | Merck & Co., Inc. | Androgen receptor modulators and methods for use thereof |
US20060269611A1 (en) * | 2001-11-29 | 2006-11-30 | Steiner Mitchell S | Prevention and treatment of androgen-deprivation induced osteoporosis |
US7105679B2 (en) * | 2001-12-19 | 2006-09-12 | Kanojia Ramesh M | Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators |
-
2005
- 2005-07-14 WO PCT/US2005/025000 patent/WO2006019916A1/en active Application Filing
- 2005-07-14 MX MX2007000050A patent/MX2007000050A/es unknown
- 2005-07-14 BR BRPI0513129-4A patent/BRPI0513129A/pt not_active IP Right Cessation
- 2005-07-14 EP EP05771501A patent/EP1776098A1/en not_active Withdrawn
- 2005-07-14 US US11/571,150 patent/US20080242726A1/en not_active Abandoned
-
2007
- 2007-02-14 EC EC2007007247A patent/ECSP077247A/es unknown
Also Published As
Publication number | Publication date |
---|---|
ECSP077247A (es) | 2007-03-29 |
EP1776098A1 (en) | 2007-04-25 |
BRPI0513129A (pt) | 2008-04-29 |
WO2006019916A1 (en) | 2006-02-23 |
US20080242726A1 (en) | 2008-10-02 |
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