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EA201890440A1 - Новые пептиды и комбинации пептидов для применения в иммунотерапии рака предстательной железы и других видов рака - Google Patents

Новые пептиды и комбинации пептидов для применения в иммунотерапии рака предстательной железы и других видов рака

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Publication number
EA201890440A1
EA201890440A1 EA201890440A EA201890440A EA201890440A1 EA 201890440 A1 EA201890440 A1 EA 201890440A1 EA 201890440 A EA201890440 A EA 201890440A EA 201890440 A EA201890440 A EA 201890440A EA 201890440 A1 EA201890440 A1 EA 201890440A1
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EA
Eurasian Patent Office
Prior art keywords
peptides
present
immunotherapy
combinations
cancer
Prior art date
Application number
EA201890440A
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English (en)
Inventor
Андреа Мар
Тони Вайншенк
Оливер Шор
Дженс Фрицше
Харприт Сингх
Филлип Мюллер
Джулия Лейбольд
Валентина Голдфингер
Original Assignee
Имматикс Байотекнолоджиз Гмбх
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Application filed by Имматикс Байотекнолоджиз Гмбх filed Critical Имматикс Байотекнолоджиз Гмбх
Publication of EA201890440A1 publication Critical patent/EA201890440A1/ru

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    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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Abstract

Настоящее изобретение относится к пептидам, белкам, нуклеиновым кислотам и клеткам для применения в иммунотерапевтических методах. В частности, настоящее изобретение относится к иммунотерапии рака. Настоящее изобретение относится далее к опухолеассоциированным пептидным эпитопам Т-клеток, в отдельности или в комбинации с другими опухолеассоциированными пептидами, которые могут, например, служить в качестве активных фармацевтических ингредиентов вакцинных композиций, стимулирующих противоопухолевые иммунные ответы, или стимулировать Т-клетки ex vivo с их перенесением в организм пациента. Пептиды, связанные с молекулами главного комплекса гистосов-местимости (МНС), или пептиды в отдельности могут быть также мишенями антител, растворимых Т-клеточных рецепторов и других связывающих молекул.
EA201890440A 2015-08-05 2016-08-05 Новые пептиды и комбинации пептидов для применения в иммунотерапии рака предстательной железы и других видов рака EA201890440A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562201289P 2015-08-05 2015-08-05
GBGB1513921.5A GB201513921D0 (en) 2015-08-05 2015-08-06 Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
PCT/EP2016/068727 WO2017021527A2 (en) 2015-08-05 2016-08-05 Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers

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EA201890440A1 true EA201890440A1 (ru) 2018-08-31

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