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EA201791950A1 - Новые пептиды и комбинации пептидов и каркасы для применения в иммунотерапии почечноклеточной карциномы (пкк) и других видов рака - Google Patents

Новые пептиды и комбинации пептидов и каркасы для применения в иммунотерапии почечноклеточной карциномы (пкк) и других видов рака

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Publication number
EA201791950A1
EA201791950A1 EA201791950A EA201791950A EA201791950A1 EA 201791950 A1 EA201791950 A1 EA 201791950A1 EA 201791950 A EA201791950 A EA 201791950A EA 201791950 A EA201791950 A EA 201791950A EA 201791950 A1 EA201791950 A1 EA 201791950A1
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EA
Eurasian Patent Office
Prior art keywords
peptides
immunotherapy
pac
framework
combinations
Prior art date
Application number
EA201791950A
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English (en)
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EA037050B1 (ru
Inventor
Андреа Мар
Тони Вайншенк
Оливер Шоор
Дженс Фрицше
Харприт Сингх
Колетт Сонг
Original Assignee
Имматикс Байотекнолоджиз Гмбх
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Publication of EA201791950A1 publication Critical patent/EA201791950A1/ru
Publication of EA037050B1 publication Critical patent/EA037050B1/ru

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    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/0636—T lymphocytes
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    • A61K35/14—Blood; Artificial blood
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Abstract

Изобретение относится к пептидам, белкам, нуклеиновым кислотам и клеткам для применения в иммунотерапевтических методах. В частности, настоящее изобретение относится к иммунотерапии рака. Настоящее изобретение относится далее к опухолеассоциированным пептидным эпитопам Т-клеток, в отдельности или в комбинации с другими опухолеассоциированными пептидами, которые могут, например, служить в качестве активных фармацевтических ингредиентов вакцинных композиций, стимулирующих противоопухолевые иммунные ответы, или стимулировать Т-клетки ex vivo с их перенесением в организм пациента. Пептиды, связанные с молекулами главного комплекса гистосовместимости (МНС), или пептиды в отдельности могут быть также мишенями антител, растворимых Т-клеточных рецепторов и других связывающих молекул.
EA201791950A 2015-03-31 2016-03-24 Новые пептиды и комбинации пептидов и каркасы для применения в иммунотерапии почечноклеточной карциномы (пкк) и других видов рака EA037050B1 (ru)

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PCT/EP2016/056601 WO2016156230A1 (en) 2015-03-31 2016-03-24 Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (rcc) and other cancers

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IL289444B (en) 2022-09-01
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IL254204B (en) 2022-06-01
MA41844A (fr) 2018-02-06
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