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EA201790332A1 - Дополнительная терапия 25-гидроксивитамином d - Google Patents

Дополнительная терапия 25-гидроксивитамином d

Info

Publication number
EA201790332A1
EA201790332A1 EA201790332A EA201790332A EA201790332A1 EA 201790332 A1 EA201790332 A1 EA 201790332A1 EA 201790332 A EA201790332 A EA 201790332A EA 201790332 A EA201790332 A EA 201790332A EA 201790332 A1 EA201790332 A1 EA 201790332A1
Authority
EA
Eurasian Patent Office
Prior art keywords
additional therapy
hydroxivitamin
hydroxyvitamin
hypocalcemia
cancer
Prior art date
Application number
EA201790332A
Other languages
English (en)
Inventor
П. Мартин Петкович
Джоел З Мельник
Джей А Уайт
Самир П. Табаш
Чарльз В. Бишоп
Сьюзан Х. Пирс
Стивен А. Страгнелл
Original Assignee
Опко Айэлэнд Глобал Холдингз Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53783233&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201790332(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Опко Айэлэнд Глобал Холдингз Лтд. filed Critical Опко Айэлэнд Глобал Холдингз Лтд.
Publication of EA201790332A1 publication Critical patent/EA201790332A1/ru

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    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
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    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
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Abstract

Раскрыты способы, композиции и наборы для дополнительной терапии с применением 25-гидроксивитамина D. 25-гидроксивитамин D можно вводить со средством, которое повышает риск развития гипокальциемии, и/или противораковым средством. Дополнительная терапия эффективна для лечения и предотвращения ятрогенной гипокальциемии и/или вторичного гиперпаратиреоза, а также для замедления прогрессирования рака и увеличения времени до первого после лечения события, связанного со скелетом.
EA201790332A 2014-08-07 2015-08-06 Дополнительная терапия 25-гидроксивитамином d EA201790332A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462034604P 2014-08-07 2014-08-07
PCT/EP2015/068219 WO2016020508A2 (en) 2014-08-07 2015-08-06 Adjunctive therapy with 25-hydroxyvitamin d

Publications (1)

Publication Number Publication Date
EA201790332A1 true EA201790332A1 (ru) 2017-06-30

Family

ID=53783233

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201790332A EA201790332A1 (ru) 2014-08-07 2015-08-06 Дополнительная терапия 25-гидроксивитамином d

Country Status (21)

Country Link
US (2) US20180085381A1 (ru)
EP (1) EP3193925A2 (ru)
JP (5) JP2017523220A (ru)
KR (2) KR20170047265A (ru)
CN (2) CN106604733A (ru)
AU (2) AU2015298858A1 (ru)
BR (1) BR112017002526A2 (ru)
CA (1) CA2957240A1 (ru)
CL (1) CL2017000317A1 (ru)
CO (2) CO2018004206A2 (ru)
CR (2) CR20210577A (ru)
EA (1) EA201790332A1 (ru)
EC (1) ECSP17014159A (ru)
IL (1) IL250462A0 (ru)
MX (1) MX2017001751A (ru)
MY (1) MY203284A (ru)
PE (1) PE20170392A1 (ru)
PH (2) PH12017500228A1 (ru)
SG (2) SG11201700858RA (ru)
TW (2) TWI778934B (ru)
WO (1) WO2016020508A2 (ru)

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SI2679228T1 (en) 2006-06-21 2018-06-29 Opko Ireland Global Holdings, Ltd. THERAPY WITH THE USE OF VITAMIN D ADDITIONAL FIBER AND HORMON RESISTANCE OF VITAMIN D
DK2148684T3 (da) 2007-04-25 2013-04-22 Cytochroma Inc Fremgangsmåde til behandling af vitamin D-insufficiens og -deficiens
SI2148661T1 (sl) 2007-04-25 2013-04-30 Cytochroma Inc. Nadzorovano oralno sproščanje sestavkov, ki vsebujejo spojino vitamina D in voskasti naosilec
RS60087B1 (sr) 2010-03-29 2020-05-29 Opko Ireland Global Holdings Ltd Postupci i kompozicije za snižavanje nivoa paratireoidnog hormona
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) * 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
US11173168B2 (en) 2016-03-28 2021-11-16 Eirgen Pharma Ltd. Methods of treating vitamin D insufficiency in chronic kidney disease
PL3246032T3 (pl) * 2016-05-20 2022-01-03 Christoph Karl Kompozycje farmaceutyczne z kwasem zoledronowym, wapniem i witaminą d, odpowiednie do leczenia i/lub profilaktyki chorób metabolicznych kości oraz działań ubocznych spowodowanych terapią, takich jak hipokalcemia
DE202017007720U1 (de) * 2016-05-20 2025-02-11 Christoph Karl Pharmazeutische Zusammensetzungen mit Anti-RANKL-Antikörpern, Kalzium und Vitamin D, geeignet zur Behandlung und/oder Prophylaxe von Erkrankungen des Knochenstoffwechsels und von therapiebedingten Nebenwirkungen wie Hypokalzämien
CN108519448B (zh) * 2018-04-04 2021-04-13 北京市心肺血管疾病研究所 25-羟基维生素d在制备大动脉炎患者疾病活动性评判试剂盒中的应用
CR20210158A (es) 2018-08-31 2021-05-21 Opko Ireland Global Holdings Ltd Formas de dosificación pediátricas de vitamina d, métodos de elaboración y uso

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KR20120005228A (ko) * 2010-07-08 2012-01-16 주식회사 네비팜 골다공증 치료용 비스포스폰산 함유 장용 약학조성물 및 그의 제조방법

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