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EA200700219A1 - ПРОИЗВОДНЫЕ ТРИАЗОЛОПИРИДИНСУЛЬФАНИЛА В КАЧЕСТВЕ ИНГИБИТОРОВ p38 МАР КИНАЗЫ - Google Patents

ПРОИЗВОДНЫЕ ТРИАЗОЛОПИРИДИНСУЛЬФАНИЛА В КАЧЕСТВЕ ИНГИБИТОРОВ p38 МАР КИНАЗЫ

Info

Publication number
EA200700219A1
EA200700219A1 EA200700219A EA200700219A EA200700219A1 EA 200700219 A1 EA200700219 A1 EA 200700219A1 EA 200700219 A EA200700219 A EA 200700219A EA 200700219 A EA200700219 A EA 200700219A EA 200700219 A1 EA200700219 A1 EA 200700219A1
Authority
EA
Eurasian Patent Office
Prior art keywords
triazolopiridinsulfanila
kinase
mar
inhibitors
derivatives
Prior art date
Application number
EA200700219A
Other languages
English (en)
Other versions
EA012119B1 (ru
Inventor
Джон Пол Матиас
Дэвид Саймон Миллан
Рассел Эндрю Льютуайт
Кристофер Филлипс
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0418015A external-priority patent/GB0418015D0/en
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of EA200700219A1 publication Critical patent/EA200700219A1/ru
Publication of EA012119B1 publication Critical patent/EA012119B1/ru

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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  • Health & Medical Sciences (AREA)
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Abstract

Соединение формулы (I), или его фармацевтически приемлемая соль, и/или сольват (включая гидрат) и использование соединения формулы (I) для лечения TNF-опосредствованных заболеваний, нарушений или состояний или р38-опосредствованных заболеваний, нарушений или состояний, особенно аллергических и не аллергических заболеваний дыхательных путей, более конкретно обструктивных или воспалительных заболеваний дыхательных путей, предпочтительно хронических обструктивных легочных заболеваний.
EA200700219A 2004-08-12 2005-08-09 ПРОИЗВОДНЫЕ ТРИАЗОЛОПИРИДИНСУЛЬФАНИЛА В КАЧЕСТВЕ ИНГИБИТОРОВ p38 MAP КИНАЗЫ EA012119B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0418015A GB0418015D0 (en) 2004-08-12 2004-08-12 New compounds
US69155905P 2005-06-17 2005-06-17
PCT/IB2005/002574 WO2006018718A2 (en) 2004-08-12 2005-08-09 Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors

Publications (2)

Publication Number Publication Date
EA200700219A1 true EA200700219A1 (ru) 2007-08-31
EA012119B1 EA012119B1 (ru) 2009-08-28

Family

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Application Number Title Priority Date Filing Date
EA200700219A EA012119B1 (ru) 2004-08-12 2005-08-09 ПРОИЗВОДНЫЕ ТРИАЗОЛОПИРИДИНСУЛЬФАНИЛА В КАЧЕСТВЕ ИНГИБИТОРОВ p38 MAP КИНАЗЫ

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US (2) US7511057B2 (ru)
EP (1) EP1778686B9 (ru)
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