DK640289D0 - Ny heterocyklisk kemi - Google Patents
Ny heterocyklisk kemiInfo
- Publication number
- DK640289D0 DK640289D0 DK640289A DK640289A DK640289D0 DK 640289 D0 DK640289 D0 DK 640289D0 DK 640289 A DK640289 A DK 640289A DK 640289 A DK640289 A DK 640289A DK 640289 D0 DK640289 D0 DK 640289D0
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- hydrogen
- alkenyl
- alkoxy
- branched
- Prior art date
Links
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- -1 3,4-methylenedioxyphenyl Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 2
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- 206010002660 Anoxia Diseases 0.000 abstract 1
- 241000976983 Anoxia Species 0.000 abstract 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000007953 anoxia Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 230000008736 traumatic injury Effects 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Priority Applications (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK640289A DK640289D0 (da) | 1989-12-18 | 1989-12-18 | Ny heterocyklisk kemi |
US07/623,868 US5102894A (en) | 1989-12-18 | 1990-12-03 | Substituted piperidine compounds and their use |
ZW191/90A ZW19190A1 (en) | 1989-12-18 | 1990-12-06 | New heterocyclic chemistry |
IL96592A IL96592A0 (en) | 1989-12-18 | 1990-12-07 | Piperidine compounds,their preparation and pharmaceutical compositions containing them |
IL9695290A IL96592A (en) | 1989-12-18 | 1990-12-07 | Piperidine compounds their preparation and pharmaceutical compositions containing them |
IE443590A IE904435A1 (en) | 1989-12-18 | 1990-12-10 | New heterocyclic chemistry |
AU69716/91A AU645722B2 (en) | 1989-12-18 | 1990-12-11 | Substituted piperidine compounds and their use |
EP91901483A EP0505465B1 (en) | 1989-12-18 | 1990-12-11 | 4-Heterocyclyl-piperidine derivatives, their preparation and their use as inhibitors of calcium overload in brain cells |
ES91901483T ES2084151T3 (es) | 1989-12-18 | 1990-12-11 | Compuestos de piperidina y una composicion farmaceutica. |
CA002071480A CA2071480A1 (en) | 1989-12-18 | 1990-12-11 | Piperidine compounds and a pharmaceutical composition |
DK91901483.7T DK0505465T3 (da) | 1989-12-18 | 1990-12-11 | 4-Heterocyclylpiperidin, deres fremstilling samt deres anvendelse som inhibitorer af calciumoverfyldning i hjerneceller |
DE69026110T DE69026110T2 (de) | 1989-12-18 | 1990-12-11 | 4-Heterocyclyl-Piperidin Derivate, deren Herstellung und deren Verwendung als Hemmstoffe der Calcium-Akkumulation in Hirnzellen |
JP3501812A JPH05502867A (ja) | 1989-12-18 | 1990-12-11 | ピペリジン化合物及び医薬組成物 |
AT91901483T ATE135704T1 (de) | 1989-12-18 | 1990-12-11 | 4-heterocyclyl-piperidin derivate, deren herstellung und deren verwendung als hemmstoffe der calcium-akkumulation in hirnzellen |
PCT/DK1990/000325 WO1991009032A1 (en) | 1989-12-18 | 1990-12-11 | Piperidine compounds and a pharmaceutical composition |
PT96235A PT96235B (pt) | 1989-12-18 | 1990-12-18 | Processo de preparacao de derivados da piperidina e de composicoes farmaceuticas que os contem |
ZA9010183A ZA9010183B (en) | 1989-12-18 | 1990-12-18 | Heterocyclic chemistry |
CN90110145A CN1052674A (zh) | 1989-12-18 | 1990-12-18 | 新的杂环化合物 |
NO922313A NO922313D0 (no) | 1989-12-18 | 1992-06-12 | Piperidinforbindelser og en farmasoeytisk sammensetning |
FI922826A FI922826L (fi) | 1989-12-18 | 1992-06-17 | Piperidinfoereningar och farmaceutisk komposition. |
NO1994003C NO1994003I1 (no) | 1989-12-18 | 1994-07-01 | Paroxetine/ (-)-trans-4-(4'-fluorophenyl)-3-((3',4'-methylenedioxyphenoxy)methyl)-piperidine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK640289A DK640289D0 (da) | 1989-12-18 | 1989-12-18 | Ny heterocyklisk kemi |
Publications (1)
Publication Number | Publication Date |
---|---|
DK640289D0 true DK640289D0 (da) | 1989-12-18 |
Family
ID=8148694
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK640289A DK640289D0 (da) | 1989-12-18 | 1989-12-18 | Ny heterocyklisk kemi |
DK91901483.7T DK0505465T3 (da) | 1989-12-18 | 1990-12-11 | 4-Heterocyclylpiperidin, deres fremstilling samt deres anvendelse som inhibitorer af calciumoverfyldning i hjerneceller |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK91901483.7T DK0505465T3 (da) | 1989-12-18 | 1990-12-11 | 4-Heterocyclylpiperidin, deres fremstilling samt deres anvendelse som inhibitorer af calciumoverfyldning i hjerneceller |
Country Status (18)
Country | Link |
---|---|
US (1) | US5102894A (da) |
EP (1) | EP0505465B1 (da) |
JP (1) | JPH05502867A (da) |
CN (1) | CN1052674A (da) |
AT (1) | ATE135704T1 (da) |
AU (1) | AU645722B2 (da) |
CA (1) | CA2071480A1 (da) |
DE (1) | DE69026110T2 (da) |
DK (2) | DK640289D0 (da) |
ES (1) | ES2084151T3 (da) |
FI (1) | FI922826L (da) |
IE (1) | IE904435A1 (da) |
IL (2) | IL96592A (da) |
NO (2) | NO922313D0 (da) |
PT (1) | PT96235B (da) |
WO (1) | WO1991009032A1 (da) |
ZA (1) | ZA9010183B (da) |
ZW (1) | ZW19190A1 (da) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2763589B1 (fr) | 1997-05-22 | 2001-01-05 | Centre Nat Rech Scient | Composes pour la preparation de medicaments destines au traitement de pathologies impliquant le glutamate extracellulaire, et leurs procedes d'obtention |
US7294637B2 (en) | 2000-09-11 | 2007-11-13 | Sepracor, Inc. | Method of treating addiction or dependence using a ligand for a monamine receptor or transporter |
AU2001290873B2 (en) * | 2000-09-11 | 2006-07-27 | Sepracor Inc. | Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission) |
WO2005032479A2 (en) | 2003-10-01 | 2005-04-14 | Unviversity Of Florida Research Foundation, Inc. | Compositions and methods for selective inhibition of nicotine acetylcholine receptors |
JP5199678B2 (ja) | 2005-02-23 | 2013-05-15 | プレクサ ファーマシューティカルズ, インコーポレイテッド | 運動障害および他のcns適応症の処置に使用することにおけるドーパミントランスポータ阻害剤 |
US20090054489A1 (en) * | 2005-02-23 | 2009-02-26 | Prexa Pharmaceuticals, Inc. | Multimediator Dopamine Transport Inhibitors, and Uses Related Thereto |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2895965A (en) * | 1959-07-21 | Process for the production of | ||
GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
DK231088D0 (da) * | 1988-04-28 | 1988-04-28 | Ferrosan As | Piperidinforbindelser, deres fremstilling og anvendelse |
US5017585A (en) * | 1986-11-03 | 1991-05-21 | Novo Nordisk A/S | Method of treating calcium overload |
IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
DK588289D0 (da) * | 1989-11-22 | 1989-11-22 | Ferrosan As | Ny heterocyklisk kemi |
-
1989
- 1989-12-18 DK DK640289A patent/DK640289D0/da not_active Application Discontinuation
-
1990
- 1990-12-03 US US07/623,868 patent/US5102894A/en not_active Expired - Fee Related
- 1990-12-06 ZW ZW191/90A patent/ZW19190A1/xx unknown
- 1990-12-07 IL IL9695290A patent/IL96592A/en not_active IP Right Cessation
- 1990-12-07 IL IL96592A patent/IL96592A0/xx unknown
- 1990-12-10 IE IE443590A patent/IE904435A1/en unknown
- 1990-12-11 AT AT91901483T patent/ATE135704T1/de not_active IP Right Cessation
- 1990-12-11 ES ES91901483T patent/ES2084151T3/es not_active Expired - Lifetime
- 1990-12-11 WO PCT/DK1990/000325 patent/WO1991009032A1/en active IP Right Grant
- 1990-12-11 JP JP3501812A patent/JPH05502867A/ja active Pending
- 1990-12-11 CA CA002071480A patent/CA2071480A1/en not_active Abandoned
- 1990-12-11 EP EP91901483A patent/EP0505465B1/en not_active Expired - Lifetime
- 1990-12-11 DK DK91901483.7T patent/DK0505465T3/da active
- 1990-12-11 DE DE69026110T patent/DE69026110T2/de not_active Expired - Fee Related
- 1990-12-11 AU AU69716/91A patent/AU645722B2/en not_active Ceased
- 1990-12-18 PT PT96235A patent/PT96235B/pt not_active IP Right Cessation
- 1990-12-18 ZA ZA9010183A patent/ZA9010183B/xx unknown
- 1990-12-18 CN CN90110145A patent/CN1052674A/zh active Pending
-
1992
- 1992-06-12 NO NO922313A patent/NO922313D0/no unknown
- 1992-06-17 FI FI922826A patent/FI922826L/fi not_active Application Discontinuation
-
1994
- 1994-07-01 NO NO1994003C patent/NO1994003I1/no unknown
Also Published As
Publication number | Publication date |
---|---|
IE904435A1 (en) | 1991-06-19 |
EP0505465B1 (en) | 1996-03-20 |
CA2071480A1 (en) | 1991-06-19 |
PT96235B (pt) | 1998-06-30 |
FI922826A0 (fi) | 1992-06-17 |
NO922313L (no) | 1992-06-12 |
DK0505465T3 (da) | 1996-08-05 |
PT96235A (pt) | 1991-09-30 |
NO1994003I1 (no) | 1994-07-01 |
WO1991009032A1 (en) | 1991-06-27 |
CN1052674A (zh) | 1991-07-03 |
AU645722B2 (en) | 1994-01-20 |
ES2084151T3 (es) | 1996-05-01 |
AU6971691A (en) | 1991-07-18 |
IL96592A0 (en) | 1991-09-16 |
US5102894A (en) | 1992-04-07 |
IL96592A (en) | 1995-06-29 |
DE69026110D1 (de) | 1996-04-25 |
EP0505465A1 (en) | 1992-09-30 |
NO922313D0 (no) | 1992-06-12 |
FI922826L (fi) | 1992-06-17 |
DE69026110T2 (de) | 1996-10-02 |
ZA9010183B (en) | 1991-10-30 |
ATE135704T1 (de) | 1996-04-15 |
JPH05502867A (ja) | 1993-05-20 |
ZW19190A1 (en) | 1991-06-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment |