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DK612689A - Peptidderivater - Google Patents

Peptidderivater Download PDF

Info

Publication number
DK612689A
DK612689A DK612689A DK612689A DK612689A DK 612689 A DK612689 A DK 612689A DK 612689 A DK612689 A DK 612689A DK 612689 A DK612689 A DK 612689A DK 612689 A DK612689 A DK 612689A
Authority
DK
Denmark
Prior art keywords
peptide derivatives
peptide
derivatives
Prior art date
Application number
DK612689A
Other languages
English (en)
Other versions
DK612689D0 (da
DK175338B1 (da
Inventor
Rainer Albert
Eric P Krenning
Steven W J Lamberts
Janos Pless
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888828364A external-priority patent/GB8828364D0/en
Priority claimed from GB898916115A external-priority patent/GB8916115D0/en
Priority claimed from GB898916761A external-priority patent/GB8916761D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK612689D0 publication Critical patent/DK612689D0/da
Publication of DK612689A publication Critical patent/DK612689A/da
Application granted granted Critical
Publication of DK175338B1 publication Critical patent/DK175338B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK198906126A 1988-12-05 1989-12-05 Somatostatinoktapeptid, fremgangsmåde til fremstilling deraf, farmaceutisk præparat og pakning med indhold deraf DK175338B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8828364 1988-12-05
GB888828364A GB8828364D0 (en) 1988-12-05 1988-12-05 Improvements in/relating to organic compounds
GB8916115 1989-07-13
GB898916115A GB8916115D0 (en) 1989-07-13 1989-07-13 Improvements in or relating to organic compounds
GB898916761A GB8916761D0 (en) 1989-07-21 1989-07-21 Improvements in or relating to organic compounds
GB8916761 1989-07-21

Publications (3)

Publication Number Publication Date
DK612689D0 DK612689D0 (da) 1989-12-05
DK612689A true DK612689A (da) 1990-06-06
DK175338B1 DK175338B1 (da) 2004-08-30

Family

ID=27264222

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198906126A DK175338B1 (da) 1988-12-05 1989-12-05 Somatostatinoktapeptid, fremgangsmåde til fremstilling deraf, farmaceutisk præparat og pakning med indhold deraf

Country Status (24)

Country Link
JP (2) JP2726320B2 (da)
KR (1) KR0156541B1 (da)
AT (1) AT403476B (da)
AU (1) AU633859B2 (da)
BE (1) BE1002296A5 (da)
CA (1) CA2004532C (da)
CH (1) CH678329A5 (da)
DE (1) DE3991505B4 (da)
DK (1) DK175338B1 (da)
ES (1) ES2023533A6 (da)
FI (1) FI102540B (da)
FR (1) FR2639947B1 (da)
GB (1) GB2225579B (da)
HK (1) HK189995A (da)
HU (2) HUT53375A (da)
IE (1) IE62091B1 (da)
IL (1) IL92534A (da)
LU (1) LU87633A1 (da)
MY (1) MY106120A (da)
NL (1) NL194828C (da)
PT (1) PT92487B (da)
SA (1) SA96160495B1 (da)
SE (1) SE508799C2 (da)
WO (1) WO1990006949A2 (da)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU639371B2 (en) * 1987-07-10 1993-07-22 Novartis Ag Method of treating breast cancer
DE3822557C2 (de) * 1987-07-10 1998-07-02 Ciba Geigy Ag Arzneimittel, enthaltend Somatostatine
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
US5460785A (en) * 1989-08-09 1995-10-24 Rhomed Incorporated Direct labeling of antibodies and other protein with metal ions
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
US5700444A (en) * 1992-02-20 1997-12-23 Rhomed Incorporated Chemotactic peptide pharmaceutical applications
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
GB9004017D0 (en) * 1990-02-22 1990-04-18 Krenning Eric P Improvements in or relating to organic compounds
US5382654A (en) * 1992-02-05 1995-01-17 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
WO1992013554A1 (en) * 1991-02-08 1992-08-20 Biomeasure, Inc. Method of treating benign and malignant proliferative skin disease
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
JPH06508357A (ja) * 1991-06-03 1994-09-22 マリンクロッド・メディカル・インコーポレイテッド 標識ポリペプチド、その製造法および使用
CA2113995C (en) * 1991-08-29 2003-04-22 Edward A. Deutsch Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
ES2155447T3 (es) * 1992-01-03 2001-05-16 Rhomed Inc Aplicaciones farmaceuticas de peptidos-iones metalicos.
US5738838A (en) * 1992-02-20 1998-04-14 Rhomed Incorporated IKVAV peptide radiopharmaceutical applications
US5556609A (en) * 1992-02-20 1996-09-17 Rhomed Incorporated YIGSR peptide radiopharmaceutical applications
US5371184A (en) * 1992-02-05 1994-12-06 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
ATE203417T1 (de) * 1992-02-05 2001-08-15 Mallinckrodt Inc Radioaktiv markierte somatostatin
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
JPH07505621A (ja) * 1992-03-25 1995-06-22 マリンクロッド・インコーポレイテッド 外科手術中における腫瘍組織の検出および探知法
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US5716596A (en) * 1992-06-23 1998-02-10 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
US5871711A (en) * 1992-06-23 1999-02-16 Diatide, Inc. Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses
US5620675A (en) * 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
EP0607103A3 (en) * 1993-01-12 1997-07-09 Sandoz Ltd Somatostatin analogs containing chelating groups and their radiolabeled compositions.
EP0683676A4 (en) * 1993-02-02 1998-09-30 Neorx Corp BIODISTRIBUTION DIRECTED FROM SMALL MOLECULES.
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
CA2167281C (en) * 1993-07-15 2001-09-04 Richard T. Dean Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
US5556939A (en) * 1994-10-13 1996-09-17 Merck Frosst Canada, Inc. TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
US5830431A (en) * 1995-06-07 1998-11-03 Mallinckrodt Medical, Inc. Radiolabeled peptide compositions for site-specific targeting
GB9708265D0 (en) * 1997-04-24 1997-06-18 Nycomed Imaging As Contrast agents
FI965181A (fi) 1996-12-20 1998-06-21 Map Medical Technologies Oy Polyalkoholi-peptidijohdannaiset
DE19917713A1 (de) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik
US6630570B1 (en) 1999-04-09 2003-10-07 Insitut für Diagnostikforschung GmbH Short-chain peptide-dye conjugates as contrast media for optical diagnosis
US7175953B2 (en) 1999-04-09 2007-02-13 Institute Fuer Diagnostik Forschung Short-warp peptide-dye conjugate as contrast agent for optical diagnostic
US6685914B1 (en) 1999-09-13 2004-02-03 Bristol-Myers Squibb Pharma Company Macrocyclic chelants for metallopharmaceuticals
ATE427125T1 (de) * 2001-04-23 2009-04-15 Mallinckrodt Inc Tc und re markierte radioaktive glycosylierte octreotid-derivate
WO2005018682A2 (en) 2003-08-20 2005-03-03 The Regents Of The University Of California Somatostatin analogs with inhibitory activity to growth hormone release
CN1867363B (zh) * 2003-09-17 2010-05-12 得克萨斯大学体系董事会 用于使胰腺显像的组合物及其用途
EP2067786A1 (en) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Novel non selective analogs of somatostatin
WO2014081655A1 (en) 2012-11-21 2014-05-30 Serene Oncology, Llc Tin-1 17m comprising somatostatin receptor binding compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1222691A (en) * 1981-12-29 1987-06-09 Wilhelmus T. Goedemans Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments
US4652519A (en) * 1983-02-03 1987-03-24 Yeda Research And Development Company Limited Bifunctional chelating agents and process for their production
US4707352A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group
DE3511206A1 (de) * 1985-03-28 1986-10-09 Sandoz-Patent-GmbH, 7850 Lörrach Neue polypeptidderivate, ihre herstellung und pharmazeutische praeparate, welche diese polypeptidderivate enthalten
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
DE3522638A1 (de) * 1985-06-25 1987-01-08 Diamalt Ag Neue somatostatin-derivate
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
AU593611B2 (en) * 1986-02-14 1990-02-15 Nihon Medi-Physics Co., Ltd. High molecular compounds having amino groups, and their utilization
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
HU906341D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Process for producing peptonic derivatives modified with sugar and pharmaceutical preparatives containing these compounds as active substance
CH679045A5 (da) * 1987-06-29 1991-12-13 Sandoz Ag
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
FR2638968B1 (fr) * 1988-11-11 1994-10-07 Sandoz Sa Nouvelle utilisation therapeutique de la somatostatine et de ses analogues et derives

Also Published As

Publication number Publication date
DE3991505B4 (de) 2006-04-20
NL194828C (nl) 2003-04-03
FI102540B1 (fi) 1998-12-31
JPH1095737A (ja) 1998-04-14
AT403476B (de) 1998-02-25
NL194828B (nl) 2002-12-02
GB2225579B (en) 1993-03-17
ATA901789A (de) 1997-07-15
FR2639947B1 (fr) 1995-04-21
DK612689D0 (da) 1989-12-05
NL8902981A (nl) 1990-07-02
HUT53375A (en) 1990-10-28
AU4587189A (en) 1990-06-14
CA2004532C (en) 2000-02-22
JP2726320B2 (ja) 1998-03-11
WO1990006949A3 (en) 1990-07-26
FI895809A0 (fi) 1989-12-04
KR900009697A (ko) 1990-07-05
HU896359D0 (en) 1990-02-28
GB8927255D0 (en) 1990-01-31
IE893866L (en) 1990-06-05
ES2023533A6 (es) 1992-01-16
SE8904087L (sv) 1991-06-05
MY106120A (en) 1995-03-31
SE8904087D0 (sv) 1989-12-04
FI102540B (fi) 1998-12-31
HK189995A (en) 1995-12-29
IL92534A (en) 1994-06-24
PT92487B (pt) 1996-01-31
HU211468A9 (en) 1995-11-28
PT92487A (pt) 1990-06-29
AU633859B2 (en) 1993-02-11
JP3686503B2 (ja) 2005-08-24
IE62091B1 (en) 1994-12-14
CH678329A5 (da) 1991-08-30
WO1990006949A2 (en) 1990-06-28
GB2225579A (en) 1990-06-06
JPH02184698A (ja) 1990-07-19
KR0156541B1 (ko) 1998-10-15
FR2639947A1 (fr) 1990-06-08
CA2004532A1 (en) 1990-06-05
SA96160495B1 (ar) 2006-08-23
SE508799C2 (sv) 1998-11-09
DK175338B1 (da) 2004-08-30
LU87633A1 (fr) 1991-09-18
BE1002296A5 (fr) 1990-11-20

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