DK437289D0 - Prodrug derivatives of thyrotropin-releasing hormone (trh) - Google Patents
Prodrug derivatives of thyrotropin-releasing hormone (trh)Info
- Publication number
- DK437289D0 DK437289D0 DK437289A DK437289A DK437289D0 DK 437289 D0 DK437289 D0 DK 437289D0 DK 437289 A DK437289 A DK 437289A DK 437289 A DK437289 A DK 437289A DK 437289 D0 DK437289 D0 DK 437289D0
- Authority
- DK
- Denmark
- Prior art keywords
- trh
- thyrotropin
- releasing hormone
- product derivatives
- derivatives
- Prior art date
Links
- XNSAINXGIQZQOO-SRVKXCTJSA-N protirelin Chemical class NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H]1NC(=O)CC1)CC1=CN=CN1 XNSAINXGIQZQOO-SRVKXCTJSA-N 0.000 title 2
- XNSAINXGIQZQOO-UHFFFAOYSA-N L-pyroglutamyl-L-histidyl-L-proline amide Natural products NC(=O)C1CCCN1C(=O)C(NC(=O)C1NC(=O)CC1)CC1=CN=CN1 XNSAINXGIQZQOO-UHFFFAOYSA-N 0.000 title 1
- 102100032251 Pro-thyrotropin-releasing hormone Human genes 0.000 title 1
- 239000000627 Thyrotropin-Releasing Hormone Substances 0.000 title 1
- 101800004623 Thyrotropin-releasing hormone Proteins 0.000 title 1
- 229940034199 thyrotropin-releasing hormone Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Metal Rolling (AREA)
- Control Of Metal Rolling (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK437289A DK437289D0 (da) | 1989-09-04 | 1989-09-04 | Prodrug derivatives of thyrotropin-releasing hormone (trh) |
| JP2512601A JPH05500061A (ja) | 1989-09-04 | 1990-09-03 | 甲状腺刺激ホルモン放出ホルモンのプロドラッグ誘導体 |
| CA002066449A CA2066449A1 (en) | 1989-09-04 | 1990-09-03 | Prodrug derivatives of thyrotropin-releasing hormone (trh) |
| US07/842,181 US5405834A (en) | 1989-09-04 | 1990-09-03 | Prodrug derivatives of thyrotropin-releasing hormone (TRH) |
| EP90913468A EP0490947A1 (en) | 1989-09-04 | 1990-09-03 | Prodrug derivatives of thyrotropin-releasing hormone (trh) |
| PCT/DK1990/000228 WO1991003487A1 (en) | 1989-09-04 | 1990-09-03 | Prodrug derivatives of thyrotropin-releasing hormone (trh) |
| KR1019920700492A KR920703628A (ko) | 1989-09-04 | 1990-09-03 | 티로트로핀-방출 호르몬(trh)의 프로드러그 유도체 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK437289A DK437289D0 (da) | 1989-09-04 | 1989-09-04 | Prodrug derivatives of thyrotropin-releasing hormone (trh) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK437289D0 true DK437289D0 (da) | 1989-09-04 |
Family
ID=8132949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK437289A DK437289D0 (da) | 1989-09-04 | 1989-09-04 | Prodrug derivatives of thyrotropin-releasing hormone (trh) |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5405834A (ja) |
| EP (1) | EP0490947A1 (ja) |
| JP (1) | JPH05500061A (ja) |
| KR (1) | KR920703628A (ja) |
| CA (1) | CA2066449A1 (ja) |
| DK (1) | DK437289D0 (ja) |
| WO (1) | WO1991003487A1 (ja) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5543390A (en) * | 1990-11-01 | 1996-08-06 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University | Covalent microparticle-drug conjugates for biological targeting |
| US5827819A (en) * | 1990-11-01 | 1998-10-27 | Oregon Health Sciences University | Covalent polar lipid conjugates with neurologically active compounds for targeting |
| US7045543B2 (en) | 2001-11-05 | 2006-05-16 | Enzrel Inc. | Covalent conjugates of biologically-active compounds with amino acids and amino acid derivatives for targeting to physiologically-protected sites |
| WO2003089459A2 (en) * | 2002-04-19 | 2003-10-30 | University Of Florida | Thyrotropin-releasing hormone analogues and their therapeutic applications |
| AU2003285200A1 (en) * | 2002-11-09 | 2004-06-03 | Nobex Corporation | Modified carbamate-containing prodrugs and methods of synthesizing same |
| US7414076B2 (en) * | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US20070010573A1 (en) * | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| US7244764B2 (en) * | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7462595B2 (en) * | 2004-09-17 | 2008-12-09 | Prange Jr Arthur Jergen | Methods for treating cancer-related fatigue |
| BRPI0517790A (pt) * | 2004-11-12 | 2008-10-21 | Neurochem Int Ltd | métodos e composições fluoradas para tratar doenças relacionadas à amilóide |
| CN101103018A (zh) * | 2004-11-16 | 2008-01-09 | 神经化学（国际）有限公司 | 治疗cns和淀粉样蛋白-相关疾病的化合物 |
| BRPI0519243A2 (pt) | 2004-12-22 | 2009-01-06 | Neurochem Int Ltd | mÉtodos e composiÇÕes para tratar doenÇas relacionadas a amilàide |
| WO2006096829A2 (en) * | 2005-03-09 | 2006-09-14 | Roger Williams Hospital | Thyrotropin-releasing hormone analogs and method of use |
| US20070232556A1 (en) * | 2006-03-31 | 2007-10-04 | Montine Thomas J | Methods and compositions for the treatment of neurological diseases and disorders |
| WO2008019394A2 (en) * | 2006-08-11 | 2008-02-14 | The Government Of The United States Of America As Represented By The Secretary, Dept Of Health And Human Services | Methods for treatment and diagnosis of psychiatric disorders |
| KR101742179B1 (ko) | 2006-10-12 | 2017-05-31 | 비에이치아이 리미티드 파트너쉽 | 3-아미노-1-프로판설폰산을 전달하기 위한 방법, 화합물, 조성물 및 비히클 |
| EP2342356A4 (en) | 2008-09-29 | 2012-11-21 | Univ Ben Gurion | AMYLOID BETA PEPTIDASES AND METHOD OF USE THEREOF |
| WO2018226992A1 (en) | 2017-06-07 | 2018-12-13 | Adrx, Inc. | Tau aggregation inhibitors |
| EP3668886A2 (en) | 2017-08-18 | 2020-06-24 | Adrx, Inc. | Tau aggregation peptide inhibitors |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3959248A (en) * | 1974-04-03 | 1976-05-25 | Merck & Co., Inc. | Analogs of thyrotropin-releasing hormone |
| GB1523598A (en) * | 1975-03-08 | 1978-09-06 | Reckitt & Colmann Prod Ltd | Tripeptides |
| CA1256650A (en) * | 1983-03-25 | 1989-06-27 | Toshinari Tamura | Process of producing 2-azetidinone-4-substituted compounds, and medicaments containing the compounds |
-
1989
- 1989-09-04 DK DK437289A patent/DK437289D0/da unknown
-
1990
- 1990-09-03 KR KR1019920700492A patent/KR920703628A/ko not_active Ceased
- 1990-09-03 JP JP2512601A patent/JPH05500061A/ja active Pending
- 1990-09-03 CA CA002066449A patent/CA2066449A1/en not_active Abandoned
- 1990-09-03 US US07/842,181 patent/US5405834A/en not_active Expired - Fee Related
- 1990-09-03 WO PCT/DK1990/000228 patent/WO1991003487A1/en not_active Application Discontinuation
- 1990-09-03 EP EP90913468A patent/EP0490947A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991003487A1 (en) | 1991-03-21 |
| EP0490947A1 (en) | 1992-06-24 |
| KR920703628A (ko) | 1992-12-18 |
| JPH05500061A (ja) | 1993-01-14 |
| US5405834A (en) | 1995-04-11 |
| CA2066449A1 (en) | 1991-03-05 |
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