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DK365785D0 - Metalcomplexer - Google Patents

Metalcomplexer

Info

Publication number
DK365785D0
DK365785D0 DK365785A DK365785A DK365785D0 DK 365785 D0 DK365785 D0 DK 365785D0 DK 365785 A DK365785 A DK 365785A DK 365785 A DK365785 A DK 365785A DK 365785 D0 DK365785 D0 DK 365785D0
Authority
DK
Denmark
Prior art keywords
metal complex
complex
metal
Prior art date
Application number
DK365785A
Other languages
English (en)
Other versions
DK365785A (da
Inventor
Francis Mueller
Dieter Schmidt
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK365785D0 publication Critical patent/DK365785D0/da
Publication of DK365785A publication Critical patent/DK365785A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046Ruthenium compounds
    • C07F15/0053Ruthenium compounds without a metal-carbon linkage
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK365785A 1984-09-17 1985-08-12 Metalcomplexer DK365785A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH443384 1984-09-17
CH298485 1985-07-10

Publications (2)

Publication Number Publication Date
DK365785D0 true DK365785D0 (da) 1985-08-12
DK365785A DK365785A (da) 1986-03-18

Family

ID=25691887

Family Applications (1)

Application Number Title Priority Date Filing Date
DK365785A DK365785A (da) 1984-09-17 1985-08-12 Metalcomplexer

Country Status (10)

Country Link
US (1) US4745076A (da)
EP (1) EP0178450B1 (da)
JP (1) JPH0690201B2 (da)
AU (1) AU586831B2 (da)
CA (1) CA1261744A (da)
DE (1) DE3582549D1 (da)
DK (1) DK365785A (da)
ES (1) ES8705634A1 (da)
NO (1) NO163694C (da)
NZ (1) NZ213420A (da)

Families Citing this family (64)

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US5221605A (en) * 1984-10-31 1993-06-22 Igen, Inc. Luminescent metal chelate labels and means for detection
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US5310687A (en) * 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
GB8601646D0 (en) * 1986-01-23 1986-02-26 Davidson R S Binding assay & reagent
US5585279A (en) * 1986-01-23 1996-12-17 Davidson; Robert S. Time-resolved luminescence binding assays using a fluorescent transition metal label other than ruthenium
US6451225B1 (en) 1986-04-30 2002-09-17 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US6316607B1 (en) 1986-04-30 2001-11-13 Igen International, Inc. Electrochemiluminescent assays
US6881536B1 (en) * 1986-04-30 2005-04-19 Bioveris Corporation Particle based electrochemiluminescent assays
EP0658564B1 (en) * 1986-04-30 2002-01-16 Igen International, Inc. Electroluminescent compounds and intermediates in their synthesis
US5591581A (en) * 1986-04-30 1997-01-07 Igen, Inc. Electrochemiluminescent rhenium moieties and methods for their use
US6165729A (en) * 1986-04-30 2000-12-26 Hyperion Catalysis International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US6881589B1 (en) * 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
JPH0682101B2 (ja) * 1988-03-25 1994-10-19 理化学研究所 pH測定用発光プローブ錯体及びpH測定法
US6702986B1 (en) 1988-04-29 2004-03-09 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
AU622899B2 (en) * 1988-05-04 1992-04-30 F. Hoffmann-La Roche Ag Rutheniumcomplex-compounds
JP2992974B2 (ja) * 1988-11-03 1999-12-20 イゲン,インコーポレーテッド 電気化学ルミネセンス検定
US5208007A (en) * 1988-11-22 1993-05-04 Board Of Regents Of The University Of Oklahoma Isotopic tracer composition and method for making and using same
CA2033692A1 (en) * 1990-01-25 1991-07-26 Wilhelm Bannwarth Energy transfer systems
US5367080A (en) * 1990-11-08 1994-11-22 Sterling Winthrop Inc. Complexing agents and targeting radioactive immunoreagents useful in therapeutic and diagnostic imaging compositions and methods
FR2673183B1 (fr) * 1991-02-21 1996-09-27 Asulab Sa Complexes mono, bis ou tris (2,2'-bipyridine substituee) d'un metal choisi parmi le fer, le ruthenium, l'osmium ou le vanadium et leurs procedes de preparation .
ZA929351B (en) * 1991-12-11 1993-06-04 Igen Inc Electrochemiluminescent label for DNA assays.
DE69231952T2 (de) * 1992-05-07 2002-04-04 Nycomed Imaging As, Oslo Komplexbildnermittel und zielimmunoreagenzien
DE59508391D1 (de) * 1994-07-25 2000-06-29 Roche Diagnostics Gmbh Metallkomplexe mit geladenem linker
CA2195648A1 (en) 1994-07-25 1996-02-08 Christoph Seidel Metal chelate-labelled peptides
US5981286A (en) * 1994-07-25 1999-11-09 Roche Diagnostics, Gmbh Hydrophilic metal complexes
NZ290810A (en) * 1994-07-25 1998-01-26 Boehringer Mannheim Gmbh Oligomer carrier molecules with selectively incorporated marker and hapten groups
ES2268694T3 (es) * 1994-07-25 2007-03-16 Roche Diagnostics Gmbh Determinacion de una inmunoglobulina especifica mediante el empleo de un antigeno multiple.
US7632651B2 (en) 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US6306661B1 (en) * 1998-02-05 2001-10-23 Joseph R. Lakowicz Water soluble luminescence oxygen sensor and method
DE19811582A1 (de) * 1998-03-17 1999-09-23 Roche Diagnostics Gmbh Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen
EP0957360B1 (de) 1998-05-06 2002-07-31 Roche Diagnostics GmbH Entstörung durch Rheumafaktoren
DE19828441A1 (de) 1998-06-25 1999-12-30 Roche Diagnostics Gmbh Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
US6410255B1 (en) * 1999-05-05 2002-06-25 Aurora Biosciences Corporation Optical probes and assays
WO2001046209A1 (en) * 1999-12-20 2001-06-28 Fluorrx, Inc. Fluorescent probes
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
DE10048417A1 (de) * 2000-09-29 2002-04-11 Roche Diagnostics Gmbh Verbindungen mit verzweigtem Linker
US6808939B2 (en) 2001-06-29 2004-10-26 Igen International, Inc. ECL labels having improved non-specific binding properties, methods of using and kits containing the same
US6664111B2 (en) * 2001-08-22 2003-12-16 3M Innovative Properties Company Fluorescence based oxygen sensor systems
DE10239098A1 (de) * 2002-08-26 2004-03-11 Roche Diagnostics Gmbh Erzeugung von Chemilumineszenz durch Wasserstoff
US7619059B2 (en) * 2003-07-29 2009-11-17 Life Technologies Corporation Bimolecular optical probes
US7727752B2 (en) * 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
CA2445420A1 (en) * 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
US20050069929A1 (en) 2003-08-08 2005-03-31 Invitrogen Corporation Methods and compositions for seamless cloning of nucleic acid molecules
EP1671128B1 (en) * 2003-09-12 2010-02-17 Life Technologies Corporation Applications of the resonance energy transfer between terbium and GFP
EP2287341B1 (en) 2003-12-01 2013-02-13 Life Technologies Corporation Nucleic acid molecules containing recombination sites and methods of using the same
JP2007523326A (ja) 2004-02-06 2007-08-16 バイエル・ヘルスケア・エルエルシー バイオセンサのための内部標準としての酸化され得る化学種、及び使用方法
JP2007538258A (ja) * 2004-05-15 2007-12-27 ジェネンテック・インコーポレーテッド 標的分子に結合親和性を有する分子を検出するためのクロススクリーニングシステムと方法
ITTO20040372A1 (it) * 2004-06-01 2004-09-01 Giuseppe Caputo Composti luminescenti aventi un braccio di legame funzionalizzato.
EP1893990B1 (en) 2005-06-03 2018-05-02 Board of Regents of the University of Texas System Electrochemistry and electrogenerated chemiluminescence with a single faradaic electrode
MX2008000836A (es) 2005-07-20 2008-03-26 Bayer Healthcare Llc Amperimetria regulada.
CA2623480C (en) 2005-09-30 2015-05-05 Bayer Healthcare Llc Gated voltammetry
US8216582B2 (en) * 2006-06-23 2012-07-10 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in cancer
IL178494A0 (en) * 2006-10-05 2007-02-11 Univ Ben Gurion Fluorescent ruthenium compounds for detecting calcium binding proteins
EP2679150B1 (en) * 2006-10-24 2020-07-22 Ascensia Diabetes Care Holdings AG Transient decay amperometry
GB0711849D0 (en) 2007-06-19 2007-07-25 Oxford Biosensors Ltd Redox Mediators
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
KR20110084280A (ko) 2008-11-03 2011-07-21 알레시아 바이오쎄라퓨틱스 인코포레이티드 종양 항원의 생물 활성을 특이적으로 차단하는 항체
CN106146664B (zh) 2011-03-31 2021-09-07 Adc治疗股份有限公司 针对肾相关抗原1的抗体及其抗原结合片段
RS58918B1 (sr) 2012-01-09 2019-08-30 Adc Therapeutics Sa Agensi za tretman trostruko negativnog raka dojke
WO2016207124A1 (en) 2015-06-25 2016-12-29 F. Hoffmann-La Roche Ag Cell based assay for determining antibody or ligand binding and function
WO2018114772A1 (en) 2016-12-21 2018-06-28 F. Hoffmann-La Roche Ag Assay for determining antibody or ligand binding and function
KR102387755B1 (ko) * 2017-10-25 2022-04-19 메르크 파텐트 게엠베하 다공성 유전체의 캡핑에 사용하기 위한 방향족 아미노 실록산 작용화 재료

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* Cited by examiner, † Cited by third party
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IL49685A (en) * 1976-05-31 1978-10-31 Technion Res & Dev Foundation Specific binding assay method for determining the concentration of materials and reagent means therefor
US4283382A (en) * 1977-12-28 1981-08-11 Eastman Kodak Company Fluorescent labels comprising rare earth chelates
SE428332B (sv) * 1979-03-08 1983-06-20 Wallac Oy Forfarande for fluorescensspektroskopisk bestemning av biologiskt aktivt emne, sasom hapten, antikropp eller antigen
US4372745A (en) * 1979-12-19 1983-02-08 Electro-Nucleonics, Inc. Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer
US4293310A (en) * 1980-03-14 1981-10-06 University Of Pittsburgh Photoelectrochemical immunoassay
US4341757A (en) * 1980-09-02 1982-07-27 Nutrition 21 Stable isotopic immunoassay method employing non-radioactive selenium label
SE454115B (sv) * 1982-09-13 1988-03-28 Wallac Oy Homogenfasanalys med lantanidkelat som merksubstans
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection

Also Published As

Publication number Publication date
NZ213420A (en) 1990-01-29
JPH0690201B2 (ja) 1994-11-14
DK365785A (da) 1986-03-18
JPS6173066A (ja) 1986-04-15
NO163694B (no) 1990-03-26
EP0178450B1 (de) 1991-04-17
AU4733485A (en) 1986-03-27
CA1261744A (en) 1989-09-26
US4745076A (en) 1988-05-17
AU586831B2 (en) 1989-07-27
ES8705634A1 (es) 1987-05-01
EP0178450A2 (de) 1986-04-23
NO853635L (no) 1986-03-18
EP0178450A3 (en) 1987-08-05
NO163694C (no) 1990-07-04
DE3582549D1 (de) 1991-05-23
ES547019A0 (es) 1987-05-01

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment