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DK365785A - Metalcomplexer - Google Patents

Metalcomplexer Download PDF

Info

Publication number
DK365785A
DK365785A DK365785A DK365785A DK365785A DK 365785 A DK365785 A DK 365785A DK 365785 A DK365785 A DK 365785A DK 365785 A DK365785 A DK 365785A DK 365785 A DK365785 A DK 365785A
Authority
DK
Denmark
Prior art keywords
metal complex
complex
metal
Prior art date
Application number
DK365785A
Other languages
English (en)
Other versions
DK365785D0 (da
Inventor
Francis Mueller
Dieter Schmidt
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK365785D0 publication Critical patent/DK365785D0/da
Publication of DK365785A publication Critical patent/DK365785A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK365785A 1984-09-17 1985-08-12 Metalcomplexer DK365785A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH443384 1984-09-17
CH298485 1985-07-10

Publications (2)

Publication Number Publication Date
DK365785D0 DK365785D0 (da) 1985-08-12
DK365785A true DK365785A (da) 1986-03-18

Family

ID=25691887

Family Applications (1)

Application Number Title Priority Date Filing Date
DK365785A DK365785A (da) 1984-09-17 1985-08-12 Metalcomplexer

Country Status (10)

Country Link
US (1) US4745076A (da)
EP (1) EP0178450B1 (da)
JP (1) JPH0690201B2 (da)
AU (1) AU586831B2 (da)
CA (1) CA1261744A (da)
DE (1) DE3582549D1 (da)
DK (1) DK365785A (da)
ES (1) ES8705634A1 (da)
NO (1) NO163694C (da)
NZ (1) NZ213420A (da)

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US6316607B1 (en) 1986-04-30 2001-11-13 Igen International, Inc. Electrochemiluminescent assays
US6451225B1 (en) 1986-04-30 2002-09-17 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US5591581A (en) * 1986-04-30 1997-01-07 Igen, Inc. Electrochemiluminescent rhenium moieties and methods for their use
US6881589B1 (en) * 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
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US6702986B1 (en) 1988-04-29 2004-03-09 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
AU622899B2 (en) * 1988-05-04 1992-04-30 F. Hoffmann-La Roche Ag Rutheniumcomplex-compounds
JP2992974B2 (ja) * 1988-11-03 1999-12-20 イゲン，インコーポレーテッド 電気化学ルミネセンス検定
US5208007A (en) * 1988-11-22 1993-05-04 Board Of Regents Of The University Of Oklahoma Isotopic tracer composition and method for making and using same
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US5367080A (en) * 1990-11-08 1994-11-22 Sterling Winthrop Inc. Complexing agents and targeting radioactive immunoreagents useful in therapeutic and diagnostic imaging compositions and methods
FR2673183B1 (fr) * 1991-02-21 1996-09-27 Asulab Sa Complexes mono, bis ou tris (2,2'-bipyridine substituee) d'un metal choisi parmi le fer, le ruthenium, l'osmium ou le vanadium et leurs procedes de preparation .
ZA929351B (en) * 1991-12-11 1993-06-04 Igen Inc Electrochemiluminescent label for DNA assays.
ATE203168T1 (de) * 1992-05-07 2001-08-15 Nycomed Imaging As Komplexbildnermittel und zielimmunoreagenzien
ATE187732T1 (de) * 1994-07-25 2000-01-15 Roche Diagnostics Gmbh Hydrophile metallkomplexe
JP3556228B2 (ja) * 1994-07-25 2004-08-18 ロシュ ダイアグノスティックス ゲーエムベーハー 複数の抗原を使用した特異的免疫グロブリンの測定
EP0774120B1 (de) 1994-07-25 2009-08-26 Roche Diagnostics GmbH Metallchelat-markierte peptide
EP0774119B1 (de) * 1994-07-25 2004-03-03 Roche Diagnostics GmbH Oligomere trägermoleküle mit definiert eingebauten markierungsgruppen und haptenen
NZ291154A (en) * 1994-07-25 1997-11-24 Boehringer Mannheim Gmbh Di- or trivalent rare earth or transition metal complexes having three ligands, each of which has at least two nitrogen-containing heterocycles and complexed through nitrogen, and at least one reactive group bound to the ligard(s)
US7632651B2 (en) 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
US6306661B1 (en) * 1998-02-05 2001-10-23 Joseph R. Lakowicz Water soluble luminescence oxygen sensor and method
DE19811582A1 (de) * 1998-03-17 1999-09-23 Roche Diagnostics Gmbh Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen
EP0957360B1 (de) 1998-05-06 2002-07-31 Roche Diagnostics GmbH Entstörung durch Rheumafaktoren
DE19828441A1 (de) * 1998-06-25 1999-12-30 Roche Diagnostics Gmbh Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
US6410255B1 (en) * 1999-05-05 2002-06-25 Aurora Biosciences Corporation Optical probes and assays
WO2001046209A1 (en) * 1999-12-20 2001-06-28 Fluorrx, Inc. Fluorescent probes
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
DE10048417A1 (de) * 2000-09-29 2002-04-11 Roche Diagnostics Gmbh Verbindungen mit verzweigtem Linker
US6808939B2 (en) 2001-06-29 2004-10-26 Igen International, Inc. ECL labels having improved non-specific binding properties, methods of using and kits containing the same
US6664111B2 (en) * 2001-08-22 2003-12-16 3M Innovative Properties Company Fluorescence based oxygen sensor systems
DE10239098A1 (de) * 2002-08-26 2004-03-11 Roche Diagnostics Gmbh Erzeugung von Chemilumineszenz durch Wasserstoff
CA2445420A1 (en) * 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
US7619059B2 (en) * 2003-07-29 2009-11-17 Life Technologies Corporation Bimolecular optical probes
US7727752B2 (en) * 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
WO2005014796A2 (en) 2003-08-08 2005-02-17 Invitrogen Corporation Methods and compositions for seamless cloning of nucleic acid molecules
DE602004025592D1 (de) * 2003-09-12 2010-04-01 Life Technologies Corp Anwendungen des Resonanzenergietransfers zwischen Terbium und GFP
EP2287341B1 (en) 2003-12-01 2013-02-13 Life Technologies Corporation Nucleic acid molecules containing recombination sites and methods of using the same
RU2006132051A (ru) 2004-02-06 2008-03-20 БАЙЕР ХЕЛТКЭР ЭлЭлСи (US) Окисляемые соединения в качестве внутреннего стандарта для биосенсоров и способ их применения
EP1769243A2 (en) * 2004-05-15 2007-04-04 Genentech, Inc. Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
ITTO20040372A1 (it) * 2004-06-01 2004-09-01 Giuseppe Caputo Composti luminescenti aventi un braccio di legame funzionalizzato.
KR101385384B1 (ko) 2005-06-03 2014-04-14 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 단일 패러데이 전극에서의 전기발생 화학발광 및 전기화학
MX2008000836A (es) 2005-07-20 2008-03-26 Bayer Healthcare Llc Amperimetria regulada.
KR101477947B1 (ko) 2005-09-30 2014-12-30 바이엘 헬스케어 엘엘씨 게이트형 전압 전류 측정 이온화제 및 헤마토크리트 결정 방법
WO2007147265A1 (en) * 2006-06-23 2007-12-27 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in cancer
IL178494A0 (en) * 2006-10-05 2007-02-11 Univ Ben Gurion Fluorescent ruthenium compounds for detecting calcium binding proteins
EP2679150B1 (en) 2006-10-24 2020-07-22 Ascensia Diabetes Care Holdings AG Transient decay amperometry
GB0711849D0 (en) 2007-06-19 2007-07-25 Oxford Biosensors Ltd Redox Mediators
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
EP3130674B1 (en) 2008-11-03 2020-07-08 ADC Therapeutics SA Antibodies that specifically block the biological activity of a tumor antigen
DK2691421T3 (da) 2011-03-31 2017-02-20 Alethia Biotherapeutics Inc Antistoffer mod nyreforbundet antigen 1 og antigenbindende fragmenter deraf
RS58918B1 (sr) 2012-01-09 2019-08-30 Adc Therapeutics Sa Agensi za tretman trostruko negativnog raka dojke
US11536716B2 (en) 2015-06-25 2022-12-27 Hoffmann-La Roche Inc. Cell based assay for determining antibody or ligand binding and function
EP3559666A1 (en) 2016-12-21 2019-10-30 H. Hoffnabb-La Roche Ag Assay for determining antibody or ligand binding and function
EP3700912B1 (en) * 2017-10-25 2022-09-14 Merck Patent GmbH Aromatic amino siloxane functionalized materials for use in capping porous dielectrics

Family Cites Families (8)

* Cited by examiner, † Cited by third party
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IL49685A (en) * 1976-05-31 1978-10-31 Technion Res & Dev Foundation Specific binding assay method for determining the concentration of materials and reagent means therefor
US4283382A (en) * 1977-12-28 1981-08-11 Eastman Kodak Company Fluorescent labels comprising rare earth chelates
SE428332B (sv) * 1979-03-08 1983-06-20 Wallac Oy Forfarande for fluorescensspektroskopisk bestemning av biologiskt aktivt emne, sasom hapten, antikropp eller antigen
US4372745A (en) * 1979-12-19 1983-02-08 Electro-Nucleonics, Inc. Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer
US4293310A (en) * 1980-03-14 1981-10-06 University Of Pittsburgh Photoelectrochemical immunoassay
US4341757A (en) * 1980-09-02 1982-07-27 Nutrition 21 Stable isotopic immunoassay method employing non-radioactive selenium label
SE454115B (sv) * 1982-09-13 1988-03-28 Wallac Oy Homogenfasanalys med lantanidkelat som merksubstans
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection

Also Published As

Publication number Publication date
NO163694C (no) 1990-07-04
CA1261744A (en) 1989-09-26
ES547019A0 (es) 1987-05-01
NO853635L (no) 1986-03-18
AU4733485A (en) 1986-03-27
EP0178450B1 (de) 1991-04-17
AU586831B2 (en) 1989-07-27
DK365785D0 (da) 1985-08-12
EP0178450A3 (en) 1987-08-05
US4745076A (en) 1988-05-17
NZ213420A (en) 1990-01-29
EP0178450A2 (de) 1986-04-23
NO163694B (no) 1990-03-26
JPS6173066A (ja) 1986-04-15
ES8705634A1 (es) 1987-05-01
DE3582549D1 (de) 1991-05-23
JPH0690201B2 (ja) 1994-11-14

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment