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DK3461491T3 - Forbedret adoptiv celleterapi - Google Patents

Forbedret adoptiv celleterapi Download PDF

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Publication number
DK3461491T3
DK3461491T3 DK18204379.4T DK18204379T DK3461491T3 DK 3461491 T3 DK3461491 T3 DK 3461491T3 DK 18204379 T DK18204379 T DK 18204379T DK 3461491 T3 DK3461491 T3 DK 3461491T3
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DK
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Prior art keywords
cell therapy
adoptive cell
improved adoptive
improved
therapy
Prior art date
Application number
DK18204379.4T
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English (en)
Inventor
Akseli Hemminki
Markus Vähä-Koskela
Siri Tähtinen
Vincenzo Cerullo
Original Assignee
Tilt Biotherapeutics Oy
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Filing date
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Publication of DK3461491T3 publication Critical patent/DK3461491T3/da

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K35/761—Adenovirus
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    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
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    • A—HUMAN NECESSITIES
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  • Health & Medical Sciences (AREA)
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  • Biotechnology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK18204379.4T 2013-04-18 2014-04-16 Forbedret adoptiv celleterapi DK3461491T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20135387 2013-04-18
EP14718086.3A EP2986311B1 (en) 2013-04-18 2014-04-16 Enhanced adoptive cell therapy

Publications (1)

Publication Number Publication Date
DK3461491T3 true DK3461491T3 (da) 2025-02-03

Family

ID=50513266

Family Applications (2)

Application Number Title Priority Date Filing Date
DK18204379.4T DK3461491T3 (da) 2013-04-18 2014-04-16 Forbedret adoptiv celleterapi
DK14718086.3T DK2986311T3 (da) 2013-04-18 2014-04-16 Forbedret adoptiv celleterapi

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK14718086.3T DK2986311T3 (da) 2013-04-18 2014-04-16 Forbedret adoptiv celleterapi

Country Status (15)

Country Link
US (2) US10647963B2 (da)
EP (3) EP3461491B1 (da)
JP (2) JP6580555B2 (da)
KR (3) KR102502974B1 (da)
CN (2) CN111658670B (da)
AU (2) AU2014255733B2 (da)
BR (1) BR112015026417B1 (da)
CA (1) CA2909432A1 (da)
DK (2) DK3461491T3 (da)
ES (1) ES2708749T3 (da)
FI (1) FI3461491T3 (da)
RU (1) RU2703438C2 (da)
SG (2) SG11201508585PA (da)
WO (1) WO2014170389A1 (da)
ZA (1) ZA201507790B (da)

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WO2014153204A1 (en) 2013-03-14 2014-09-25 Salk Institute For Biological Studies Oncolytic adenovirus compositions
HUE043463T2 (hu) 2013-09-18 2019-08-28 Aura Biosciences Inc Vírusszerû részecske konjugátumok tumorok kezelésére
EP4043021A3 (en) * 2014-09-24 2022-11-23 Salk Institute for Biological Studies Oncolytic tumor viruses and methods of use
AU2016232009B2 (en) 2015-03-17 2021-07-15 Tilt Biotherapeutics Oy Oncolytic adenoviruses coding for bi-specific antibodies and methods and uses related thereto
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CA2998789A1 (en) 2015-09-16 2017-03-23 Herlev Hospital Vaccine compositions comprising c-c motif chemokine 22 (ccl22) or fragments thereof
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
WO2017147269A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
CN108778301A (zh) 2016-03-10 2018-11-09 永恒生物科技股份有限公司 通过联合疗法来治疗实体瘤或淋巴瘤的方法
EP3478321A4 (en) 2016-06-30 2020-04-22 Oncorus, Inc. PSEUDOTYPIZED ONCOLYTIC VIRAL ADMINISTRATION OF THERAPEUTIC POLYPEPTIDES
FI20165814A (fi) 2016-10-27 2018-04-28 Tilt Biotherapeutics Oy Interleukiini 8 (il-8) prognostisena ja ennustavana biomarkkerina ja koostumukset ja vektorit käytettäväksi onkolyyttisessa immunoterapiassa
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WO2018118967A1 (en) * 2016-12-21 2018-06-28 Memgen, Llc Armed replication-competent oncolytic adenoviruses
US10232053B2 (en) * 2016-12-30 2019-03-19 Trieza Therapeutics, Inc. Immunomodulatory oncolytic adenoviral vectors, and methods of production and use thereof for treatment of cancer
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US20190352616A1 (en) * 2017-01-30 2019-11-21 Epicentrx, Inc. Multiple transgene recombinant adenovirus
EA201990822A1 (ru) * 2017-04-12 2020-01-09 Эписентарикс, Инк. Иммуномодулирующие слитые белки
US11338003B2 (en) * 2017-04-14 2022-05-24 Cg Oncology, Inc. Methods of treating bladder cancer with an oncolytic virus
EP4389900A3 (en) * 2017-05-17 2024-12-18 Seattle Children's Hospital (DBA Seattle Children's Research Institute) Generating mammalian t cell activation inducible synthetic promoters (syn+pro) to improve t cell therapy
CN109276580B (zh) * 2017-07-21 2021-08-24 厦门大学 一种用于治疗肿瘤的病毒
SG11201911572YA (en) 2017-07-25 2020-02-27 Oxford Genetics Ltd Adenoviral vectors
KR20200036874A (ko) * 2017-08-03 2020-04-07 타이가 바이오테크놀로지스, 인코포레이티드 암 치료를 위한 방법 및 조성물
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