DK3129400T3 - Ikke-humane dyr med humaniserede Fc-gamma-receptorer - Google Patents

Ikke-humane dyr med humaniserede Fc-gamma-receptorer Download PDF

Info

Publication number: DK3129400T3
Authority: DK; Denmark
Prior art keywords: humanized; human animals; gamma receptors; receptors; gamma
Prior art date: 2014-04-08

Application number

DK15718060.5T

Other languages

English (en)

Inventor

Andrew J Murphy

Lynn Macdonald

Karolina A Meagher

Naxin Tu

Cagan Gurer

Original Assignee

Regeneron Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-04-08

Filing date

2015-04-08

Publication date

2020-06-08

2015-04-08 Application filed by Regeneron Pharma filed Critical Regeneron Pharma

2020-06-08 Application granted granted Critical

2020-06-08 Publication of DK3129400T3 publication Critical patent/DK3129400T3/da

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0337—Animal models for infectious diseases
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0387—Animal model for diseases of the immune system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Environmental Sciences (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Biodiversity & Conservation Biology (AREA)
Engineering & Computer Science (AREA)
Animal Husbandry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Cell Biology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Electric Clocks (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK15718060.5T 2014-04-08 2015-04-08 Ikke-humane dyr med humaniserede Fc-gamma-receptorer DK3129400T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201461977037P	2014-04-08	2014-04-08
PCT/US2015/024920 WO2015157415A1 (en)	2014-04-08	2015-04-08	Non-human animals having humanized fc-gamma receptors

Publications (1)

Publication Number	Publication Date
DK3129400T3 true DK3129400T3 (da)	2020-06-08

Family

ID=52997579

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK15718060.5T DK3129400T3 (da)	2014-04-08	2015-04-08	Ikke-humane dyr med humaniserede Fc-gamma-receptorer

Country Status (24)

Country	Link
US (4)	US9474255B2 (da)
EP (2)	EP3693383A1 (da)
JP (2)	JP6652931B2 (da)
KR (2)	KR102439412B1 (da)
CN (2)	CN106163273B (da)
AU (2)	AU2015243865C1 (da)
CA (1)	CA2935472C (da)
CY (1)	CY1123046T1 (da)
DK (1)	DK3129400T3 (da)
ES (1)	ES2794942T3 (da)
HR (1)	HRP20200899T1 (da)
HU (1)	HUE051088T2 (da)
IL (2)	IL246497B (da)
LT (1)	LT3129400T (da)
MX (1)	MX2016013241A (da)
PH (1)	PH12016501341A1 (da)
PL (1)	PL3129400T3 (da)
PT (1)	PT3129400T (da)
RS (1)	RS60398B1 (da)
RU (2)	RU2019128394A (da)
SG (2)	SG11201604886WA (da)
SI (1)	SI3129400T1 (da)
SM (1)	SMT202000332T1 (da)
WO (1)	WO2015157415A1 (da)

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CN116848254A (zh)	2020-12-16	2023-10-03	瑞泽恩制药公司	表达人源化Fcα受体的小鼠
CN114410643B (zh) *	2021-02-02	2024-08-02	百奥赛图(北京)医药科技股份有限公司	FcRn基因人源化的非人动物及其构建方法和应用

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2015
- 2015-04-08 SG SG11201604886WA patent/SG11201604886WA/en unknown
- 2015-04-08 CA CA2935472A patent/CA2935472C/en active Active
- 2015-04-08 ES ES15718060T patent/ES2794942T3/es active Active
- 2015-04-08 MX MX2016013241A patent/MX2016013241A/es unknown
- 2015-04-08 EP EP20156988.6A patent/EP3693383A1/en active Pending
- 2015-04-08 HU HUE15718060A patent/HUE051088T2/hu unknown
- 2015-04-08 RU RU2019128394A patent/RU2019128394A/ru unknown
- 2015-04-08 LT LTEP15718060.5T patent/LT3129400T/lt unknown
- 2015-04-08 KR KR1020217005817A patent/KR102439412B1/ko active Active
- 2015-04-08 WO PCT/US2015/024920 patent/WO2015157415A1/en not_active Ceased
- 2015-04-08 PL PL15718060T patent/PL3129400T3/pl unknown
- 2015-04-08 SM SM20200332T patent/SMT202000332T1/it unknown
- 2015-04-08 SI SI201531233T patent/SI3129400T1/sl unknown
- 2015-04-08 RS RS20200649A patent/RS60398B1/sr unknown
- 2015-04-08 JP JP2016561676A patent/JP6652931B2/ja active Active
- 2015-04-08 CN CN201580019102.0A patent/CN106163273B/zh active Active
- 2015-04-08 EP EP15718060.5A patent/EP3129400B1/en active Active
- 2015-04-08 RU RU2016143036A patent/RU2700484C2/ru active
- 2015-04-08 HR HRP20200899TT patent/HRP20200899T1/hr unknown
- 2015-04-08 PT PT157180605T patent/PT3129400T/pt unknown
- 2015-04-08 CN CN202010590143.8A patent/CN111690052B/zh active Active
- 2015-04-08 KR KR1020167027893A patent/KR102223264B1/ko active Active
- 2015-04-08 DK DK15718060.5T patent/DK3129400T3/da active
- 2015-04-08 US US14/681,617 patent/US9474255B2/en active Active
- 2015-04-08 SG SG10201908800Y patent/SG10201908800YA/en unknown
- 2015-04-08 AU AU2015243865A patent/AU2015243865C1/en active Active
2016
- 2016-06-28 IL IL246497A patent/IL246497B/en active IP Right Grant
- 2016-07-05 PH PH12016501341A patent/PH12016501341A1/en unknown
- 2016-09-27 US US15/277,092 patent/US10555507B2/en active Active
2019
- 2019-01-21 IL IL264364A patent/IL264364B/en active IP Right Grant
- 2019-12-20 US US16/723,733 patent/US11503812B2/en active Active
2020
- 2020-01-24 JP JP2020009985A patent/JP6858283B2/ja active Active
- 2020-06-16 CY CY20201100549T patent/CY1123046T1/el unknown
- 2020-08-10 AU AU2020217312A patent/AU2020217312C1/en active Active
2022
- 2022-10-17 US US17/967,510 patent/US20230232795A1/en active Pending

Also Published As

Publication number	Publication date
EP3129400B1 (en)	2020-03-25
SG11201604886WA (en)	2016-07-28
MX2016013241A (es)	2017-05-03
KR20210024249A (ko)	2021-03-04
EP3693383A1 (en)	2020-08-12
ES2794942T3 (es)	2020-11-19
AU2020217312C1 (en)	2023-10-26
US20200288684A1 (en)	2020-09-17
CN111690052B (zh)	2024-06-04
IL246497A0 (en)	2016-08-31
RU2019128394A (ru)	2019-10-07
AU2020217312B2 (en)	2023-04-13
CN106163273B (zh)	2020-07-24
AU2015243865B2 (en)	2020-05-14
CN106163273A (zh)	2016-11-23
RU2016143036A3 (da)	2018-10-24
US20170086432A1 (en)	2017-03-30
RS60398B1 (sr)	2020-07-31
PL3129400T3 (pl)	2020-09-07
CN111690052A (zh)	2020-09-22
PH12016501341A1 (en)	2016-08-15
US10555507B2 (en)	2020-02-11
PT3129400T (pt)	2020-05-27
KR102439412B1 (ko)	2022-09-02
IL264364A (en)	2019-02-28
AU2015243865A1 (en)	2016-08-18
HRP20200899T1 (hr)	2020-09-04
JP6652931B2 (ja)	2020-02-26
JP6858283B2 (ja)	2021-04-14
US9474255B2 (en)	2016-10-25
SMT202000332T1 (it)	2020-07-08
RU2700484C2 (ru)	2019-09-17
CA2935472A1 (en)	2015-10-15
JP2017510285A (ja)	2017-04-13
HUE051088T2 (hu)	2021-03-01
CA2935472C (en)	2024-02-20
US20150282463A1 (en)	2015-10-08
LT3129400T (lt)	2020-06-25
SI3129400T1 (sl)	2020-07-31
EP3129400A1 (en)	2017-02-15
SG10201908800YA (en)	2019-11-28
CY1123046T1 (el)	2021-10-29
AU2015243865C1 (en)	2020-11-26
RU2016143036A (ru)	2018-05-08
KR20160142309A (ko)	2016-12-12
US20230232795A1 (en)	2023-07-27
IL264364B (en)	2021-03-25
US11503812B2 (en)	2022-11-22
WO2015157415A1 (en)	2015-10-15
KR102223264B1 (ko)	2021-03-09
AU2020217312A1 (en)	2020-08-27
IL246497B (en)	2019-06-30
JP2020062051A (ja)	2020-04-23

Publication	Publication Date	Title
DK3129400T3 (da)	2020-06-08	Ikke-humane dyr med humaniserede Fc-gamma-receptorer
IL251030B (en)	2021-07-29	Chimeric antigen receptors
DK3850946T3 (da)	2024-01-08	Ikke-humane dyr med en humaniseret klynge af differentiering af 47-gen
CL2016002196A1 (es)	2018-02-16	Receptor antigénico quimérico
EP3636073C0 (en)	2023-11-15	HUMANIZED C5 AND C3 ANIMALS
HUE047929T2 (hu)	2020-05-28	Kiméra antigén receptor
LT3689140T (lt)	2022-08-25	Gyvūnai, išskyrus žmones, ekspresuojantys humanizuotą cd3 kompleksą
SI3230310T1 (sl)	2019-11-29	Anti-CD70 himerni antigenski receptorji
DK3104909T3 (da)	2019-10-28	Automatisk injektionsindretning
BR112016015364A2 (pt)	2017-08-08	Injetor automático
IL247371A0 (en)	2016-11-30	Antibodies from individuals with increased stability
DK4268843T3 (da)	2025-11-10	Forbedrede IL-6-antistoffer
ITUB20155097A1 (it)	2017-05-05	Anticorpi umanizzati anti-BAG3
DK3192852T3 (da)	2019-06-03	Brændstofadditiv
ES1129630Y (es)	2015-01-20	Escurridor automatico
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