DK2967049T3 - Metoder, forbindelser og sammensætninger til behandlingen af angiotensin relaterede sygdomme - Google Patents
Metoder, forbindelser og sammensætninger til behandlingen af angiotensin relaterede sygdomme Download PDFInfo
- Publication number
- DK2967049T3 DK2967049T3 DK14763703.7T DK14763703T DK2967049T3 DK 2967049 T3 DK2967049 T3 DK 2967049T3 DK 14763703 T DK14763703 T DK 14763703T DK 2967049 T3 DK2967049 T3 DK 2967049T3
- Authority
- DK
- Denmark
- Prior art keywords
- angiotensin
- compositions
- compounds
- treatment
- methods
- Prior art date
Links
- 102000015427 Angiotensins Human genes 0.000 title 1
- 108010064733 Angiotensins Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/52—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361802259P | 2013-03-15 | 2013-03-15 | |
| US201361809290P | 2013-04-05 | 2013-04-05 | |
| PCT/US2014/030071 WO2014145331A1 (en) | 2013-03-15 | 2014-03-15 | Methods, compounds, and compositions for the treatment of angiotensin-related diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2967049T3 true DK2967049T3 (da) | 2020-12-07 |
Family
ID=51537955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14763703.7T DK2967049T3 (da) | 2013-03-15 | 2014-03-15 | Metoder, forbindelser og sammensætninger til behandlingen af angiotensin relaterede sygdomme |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9732074B2 (da) |
| EP (2) | EP2967049B1 (da) |
| JP (1) | JP6480909B2 (da) |
| KR (1) | KR102230461B1 (da) |
| CN (1) | CN105451554B (da) |
| AU (1) | AU2014233185B2 (da) |
| CA (1) | CA2911376C (da) |
| DK (1) | DK2967049T3 (da) |
| ES (1) | ES2834430T3 (da) |
| HK (1) | HK1220324A1 (da) |
| NZ (1) | NZ712479A (da) |
| RU (1) | RU2688163C2 (da) |
| WO (1) | WO2014145331A1 (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2967049T3 (da) | 2013-03-15 | 2020-12-07 | Univ Southern California | Metoder, forbindelser og sammensætninger til behandlingen af angiotensin relaterede sygdomme |
| EP2968441A1 (en) | 2013-03-15 | 2016-01-20 | University of Southern California | Methods for treating multiple sclerosis |
| RU2015147241A (ru) * | 2013-05-24 | 2017-06-29 | Терикс Фармасьютикалз Лтд. | Пептиды ангиотензина при лечении синдрома марфана и связанных с ним нарушений |
| KR20170026368A (ko) * | 2014-07-17 | 2017-03-08 | 유니버시티 오브 써던 캘리포니아 | 근골격 질환들의 치료를 위한 방법들, 화합물들 및 조성물들 |
| WO2018005591A1 (en) | 2016-06-29 | 2018-01-04 | Universite De Montreal | Biarylmethyl heterocycles |
| US11446285B2 (en) | 2017-06-16 | 2022-09-20 | University Of Southern California | Methods for treating systemic lupus erythematosus |
| WO2019027890A1 (en) * | 2017-08-04 | 2019-02-07 | Gaffney Kevin J | METHODS OF TREATING MYELOSUPPRESSION |
| US11786511B2 (en) | 2017-08-16 | 2023-10-17 | University Of Southern California | Methods for increasing circulating mesenchymal stem cells |
| JOP20180092A1 (ar) | 2017-10-13 | 2019-04-13 | Gilead Sciences Inc | مثبطات hiv بروتياز |
| US11833148B2 (en) | 2018-05-11 | 2023-12-05 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods for treating or limiting development of cardiovascular disease-related neurological disorders |
| CA3121202A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| TW202104210A (zh) | 2019-04-17 | 2021-02-01 | 美商基利科學股份有限公司 | Hiv蛋白酶抑制劑 |
| WO2021189038A1 (en) * | 2020-03-20 | 2021-09-23 | The Board Of Trustees Of The Leland Stanford Junior University | Ang 1-7 as a therapeutic for coronavirus |
| KR20230156030A (ko) * | 2021-01-28 | 2023-11-13 | 케퍼시티 바이오 인코포레이티드 | 질환 치료를 위해 미토콘드리아 전환을 자극하는 방법 및 제제 |
| EP4220172A1 (en) | 2022-01-27 | 2023-08-02 | Université Libre de Bruxelles | Covid-19 theranostic |
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| DK2967049T3 (da) | 2013-03-15 | 2020-12-07 | Univ Southern California | Metoder, forbindelser og sammensætninger til behandlingen af angiotensin relaterede sygdomme |
| EP2991663B1 (en) | 2013-04-30 | 2017-09-13 | University of Southern California | Accelerated healing of eye injuries by angiotensin peptides |
-
2014
- 2014-03-15 DK DK14763703.7T patent/DK2967049T3/da active
- 2014-03-15 EP EP14763703.7A patent/EP2967049B1/en active Active
- 2014-03-15 WO PCT/US2014/030071 patent/WO2014145331A1/en active Application Filing
- 2014-03-15 NZ NZ712479A patent/NZ712479A/en unknown
- 2014-03-15 CA CA2911376A patent/CA2911376C/en active Active
- 2014-03-15 CN CN201480027988.9A patent/CN105451554B/zh active Active
- 2014-03-15 US US14/773,041 patent/US9732074B2/en active Active
- 2014-03-15 AU AU2014233185A patent/AU2014233185B2/en active Active
- 2014-03-15 JP JP2016503327A patent/JP6480909B2/ja active Active
- 2014-03-15 EP EP20188953.2A patent/EP3935944A1/en active Pending
- 2014-03-15 RU RU2015138801A patent/RU2688163C2/ru active
- 2014-03-15 ES ES14763703T patent/ES2834430T3/es active Active
- 2014-03-15 KR KR1020157029160A patent/KR102230461B1/ko active IP Right Grant
-
2016
- 2016-07-08 HK HK16108005.8A patent/HK1220324A1/zh unknown
-
2017
- 2017-07-12 US US15/648,184 patent/US10301298B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2911376C (en) | 2021-03-30 |
| EP2967049B1 (en) | 2020-09-02 |
| AU2014233185A1 (en) | 2015-10-29 |
| CA2911376A1 (en) | 2014-09-18 |
| RU2015138801A (ru) | 2017-04-20 |
| US20160016946A1 (en) | 2016-01-21 |
| RU2688163C2 (ru) | 2019-05-20 |
| KR20150138242A (ko) | 2015-12-09 |
| JP2016514702A (ja) | 2016-05-23 |
| CN105451554B (zh) | 2019-06-11 |
| AU2014233185B2 (en) | 2018-03-15 |
| EP2967049A1 (en) | 2016-01-20 |
| EP2967049A4 (en) | 2017-01-11 |
| HK1220324A1 (zh) | 2017-05-05 |
| ES2834430T3 (es) | 2021-06-17 |
| US20180030042A1 (en) | 2018-02-01 |
| KR102230461B1 (ko) | 2021-03-22 |
| US10301298B2 (en) | 2019-05-28 |
| US9732074B2 (en) | 2017-08-15 |
| WO2014145331A1 (en) | 2014-09-18 |
| JP6480909B2 (ja) | 2019-03-13 |
| EP3935944A1 (en) | 2022-01-12 |
| CN105451554A (zh) | 2016-03-30 |
| NZ712479A (en) | 2019-01-25 |
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