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DK2683384T3 - Fremgangsmåder til behandling af cancer under anvendelse af 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidin-2,6-dion - Google Patents

Fremgangsmåder til behandling af cancer under anvendelse af 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidin-2,6-dion Download PDF

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Publication number
DK2683384T3
DK2683384T3 DK12710836.3T DK12710836T DK2683384T3 DK 2683384 T3 DK2683384 T3 DK 2683384T3 DK 12710836 T DK12710836 T DK 12710836T DK 2683384 T3 DK2683384 T3 DK 2683384T3
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Prior art keywords
dion
quinazolin
piperidin
oxo
amino
Prior art date
Application number
DK12710836.3T
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English (en)
Inventor
George W Muller
Peter H Schafer
Hon-Wah Man
Ling-Hua Zhang
Anita Gandhi
Rajesh Chopra
Original Assignee
Celgene Corp
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Publication of DK2683384T3 publication Critical patent/DK2683384T3/da

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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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DK12710836.3T 2011-03-11 2012-03-09 Fremgangsmåder til behandling af cancer under anvendelse af 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidin-2,6-dion DK2683384T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161451995P 2011-03-11 2011-03-11
US201161480272P 2011-04-28 2011-04-28
PCT/US2012/028498 WO2012125459A1 (en) 2011-03-11 2012-03-09 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione

Publications (1)

Publication Number Publication Date
DK2683384T3 true DK2683384T3 (da) 2016-02-08

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DK12710836.3T DK2683384T3 (da) 2011-03-11 2012-03-09 Fremgangsmåder til behandling af cancer under anvendelse af 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidin-2,6-dion

Country Status (29)

Country Link
US (6) US20140148473A1 (da)
EP (3) EP3025715A1 (da)
JP (5) JP2014510078A (da)
KR (2) KR20140025374A (da)
CN (3) CN107375293A (da)
AR (1) AR085651A1 (da)
AU (4) AU2012229300B2 (da)
BR (2) BR112013023280A2 (da)
CA (2) CA2829592A1 (da)
CY (1) CY1117430T1 (da)
DK (1) DK2683384T3 (da)
EA (2) EA201691939A1 (da)
ES (2) ES2659205T3 (da)
HR (1) HRP20160056T1 (da)
HU (1) HUE027481T2 (da)
IL (2) IL227990B (da)
MX (2) MX2013010217A (da)
NI (2) NI201300082A (da)
PH (2) PH12013501820A1 (da)
PL (1) PL2683384T3 (da)
PT (1) PT2683384E (da)
RS (1) RS54553B1 (da)
RU (3) RU2013145556A (da)
SG (2) SG192947A1 (da)
SI (1) SI2683384T1 (da)
SM (1) SMT201600034B (da)
TW (2) TWI542349B (da)
WO (2) WO2012125459A1 (da)
ZA (2) ZA201306148B (da)

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TW201540323A (zh) * 2014-01-15 2015-11-01 Celgene Corp ３－（５－胺基－２－甲基－４－側氧基－４ｈ－喹唑啉－３－基）－哌啶－２，６－二酮之調配物
EP3160486B1 (en) 2014-06-27 2020-11-18 Celgene Corporation Compositions and methods for inducing conformational changes in cereblon other e3 ubiquitin ligases
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