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CY1117430T1 - Μεθοδοι θεραπειας καρκινου χρησιμοποιωντας 3-(5-αμινο-2-μεθυλ-4-οξο-4η-κιναζολιν-3-υλ)-πιπεριδινο-2,6-διονη - Google Patents

Μεθοδοι θεραπειας καρκινου χρησιμοποιωντας 3-(5-αμινο-2-μεθυλ-4-οξο-4η-κιναζολιν-3-υλ)-πιπεριδινο-2,6-διονη

Info

Publication number
CY1117430T1
CY1117430T1 CY20161100088T CY161100088T CY1117430T1 CY 1117430 T1 CY1117430 T1 CY 1117430T1 CY 20161100088 T CY20161100088 T CY 20161100088T CY 161100088 T CY161100088 T CY 161100088T CY 1117430 T1 CY1117430 T1 CY 1117430T1
Authority
CY
Cyprus
Prior art keywords
oxo
amino
methyl
methods
kinazolin
Prior art date
Application number
CY20161100088T
Other languages
English (en)
Inventor
George W Muller
Peter H Schafer
Hon-Wah Man
Ling-Hua Zhang
Anita Gandhi
Rajesh Chopra
Original Assignee
Celgene Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corporation filed Critical Celgene Corporation
Publication of CY1117430T1 publication Critical patent/CY1117430T1/el

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Abstract

Στο παρόν παρέχονται μέθοδοι θεραπείας, πρόληψης ή/και χειρισμού καρκίνων, που περιλαμβάνουν χορήγηση σε έναν ασθενή, 3-(5-αμινο-2-μεθυλ-4-οξο-4Η-κιναζολιν-3-υλ)-πιπεριδινο-2,6-διόνης ή εναντιομερές ή μείγμα εναντιομερών αυτής, ή φαρμακευτικώς αποδεκτό άλας, διαλύτωμα, υδρίτη, συν-κρύσταλλο, κλαθρικό ή πολύμορφο αυτής.
CY20161100088T 2011-03-11 2016-02-02 Μεθοδοι θεραπειας καρκινου χρησιμοποιωντας 3-(5-αμινο-2-μεθυλ-4-οξο-4η-κιναζολιν-3-υλ)-πιπεριδινο-2,6-διονη CY1117430T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161451995P 2011-03-11 2011-03-11
US201161480272P 2011-04-28 2011-04-28
EP12710836.3A EP2683384B1 (en) 2011-03-11 2012-03-09 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione

Publications (1)

Publication Number Publication Date
CY1117430T1 true CY1117430T1 (el) 2017-04-26

Family

ID=45876915

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161100088T CY1117430T1 (el) 2011-03-11 2016-02-02 Μεθοδοι θεραπειας καρκινου χρησιμοποιωντας 3-(5-αμινο-2-μεθυλ-4-οξο-4η-κιναζολιν-3-υλ)-πιπεριδινο-2,6-διονη

Country Status (30)

Country Link
US (6) US20140148473A1 (el)
EP (3) EP2683383B1 (el)
JP (5) JP2014510078A (el)
KR (2) KR20140025374A (el)
CN (3) CN103561743A (el)
AR (1) AR085651A1 (el)
AU (4) AU2012229300B2 (el)
BR (2) BR112013023280A2 (el)
CA (2) CA2829593A1 (el)
CY (1) CY1117430T1 (el)
DK (1) DK2683384T3 (el)
EA (2) EA201391319A1 (el)
ES (2) ES2562332T3 (el)
HK (1) HK1191858A1 (el)
HR (1) HRP20160056T1 (el)
HU (1) HUE027481T2 (el)
IL (2) IL227990B (el)
MX (2) MX2013010217A (el)
NI (2) NI201300081A (el)
PH (2) PH12013501837A1 (el)
PL (1) PL2683384T3 (el)
PT (1) PT2683384E (el)
RS (1) RS54553B1 (el)
RU (3) RU2013145556A (el)
SG (2) SG192947A1 (el)
SI (1) SI2683384T1 (el)
SM (1) SMT201600034B (el)
TW (2) TWI542349B (el)
WO (2) WO2012125459A1 (el)
ZA (2) ZA201306148B (el)

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