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DK2552517T3 - Lægemiddelafgivelsesindretning omfattende feedback-signaleringsmidler - Google Patents

Lægemiddelafgivelsesindretning omfattende feedback-signaleringsmidler Download PDF

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DK2552517T3
DK2552517T3 DK11763137.4T DK11763137T DK2552517T3 DK 2552517 T3 DK2552517 T3 DK 2552517T3 DK 11763137 T DK11763137 T DK 11763137T DK 2552517 T3 DK2552517 T3 DK 2552517T3
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tubular
tubular extension
delivery device
actuator
distal
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DK11763137.4T
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Mattias Daniel
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Shl Group Ab
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M5/142—Pressure infusion, e.g. using pumps
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    • A—HUMAN NECESSITIES
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    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
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Claims (7)

1. Lægemiddelafgivelsesindretning (1) omfattende: - et rørformet hus (20) med en proximal ende (11) og en modsatliggende distal ende (12); - en drivmekanisme konfigureret til at påvirke en lægemiddelbeholder til udstødning af et lægemiddel; - et holdemiddel konfigureret til at holde drivmekanismen i en forspændt tilstand; - et aktiveringsmiddel konfigureret til at samvirke med holdemidlet til frigørelse af drivmekanismen fra den forspændte tilstand, hvor aktiveringsmidlet er et rørformet aktiveringsorgan (30), der kan glide og er anbragt koaksialt i forhold til det rørformede hus (20); og - en beholderholder (50) anbragt koaksialt inden i det rørformede aktiveringsorgan (30) fast forbundet til det rørformede hus (20), hvor lægemiddelbeholderen (80) er anbragt i beholderholderen (50), og hvor lægemiddelbeholderen omfatter et forudbestemt volumen af lægemiddel, en glidbar stopper (83) og en afgivelsesdel (61), hvor drivmidlet omfatter en stempelstang (90) og en første elastisk del (91), som er anbragt forspændt i stempelstangen, og hvor stempelstangen er indrettet til at være i kontakt med den glidbare stopper i lægemiddelbeholderen, hvor holdemidlet er en rørformet forlængelsesdel (22), der er fast forbundet til den distale ende af det rørformede hus (20), og et rørformet betjeningsorgan (100), som er drejeligt og anbragt koaksialt på en proximal del af den rørformede forlængelsesdel, der er interaktivt forbundet til både den rørformede forlængelsesdel og det rørformede aktiveringsorgan, således at når det rørformede aktiveringsorgan presses mod et afgivelsessted, drejer det rørformede betjeningsorgan sig i forhold til den rørformede forlængelsesdel, hvorved drivmekanismen udløses af den forspændte tilstand til udøvelse af et tryk på den glidbare stopper (83) og derved udstøder lægemidlet, hvor indretningen yderligere omfatter feedback-midler, der er konfigureret til at samvirke både med holdemidlet og med drivmidlet til frembringelse af et hørligt og/eller føleligt og/eller visuelt signal, der angiver, at lægemidlet er blevet udstødt fuldstændigt, kendetegnet ved, at feedback-midlet er et langstrakt signalgivende organ (110) , som er interaktivt forbundet til den rørformede forlængelsesdel og til drivmidlet, således at når stempelstangen er fuldstændigt frigjort fra den rørformede forlængelsesdel og det langstrakte signalgivende organ, frigøres det langstrakte signalgivende organ fra den rørformede forlængelsesdel og forskydes distalt ved hjælp af en resterende kraft i den første elastiske del tril generering af et hørligt og/eller føleligt og/eller visuelt signal, der angiver, at lægemidlet er blevet udstødt fuldstændigt, hvorved det langstrakte signalgivende organ (110) er anbragt løsbart på en indre overflade af den rørformede forlængelsesdel (22), hvor det langstrakte signalgivende organ (110) er en langstrakt U-formet konsol omfattende en tværvæg (112) og to langsgående, fleksible arme (111) udstyret med vinkelbøjede støtteorganer (113), der strækker sig radialt udad, og hvor støtteorganerne (113) er indrettet til at hvile på en ringformet, proximal ende af den rørformede forlængelsesdel (22), når drivmidlet er i den forspændte tilstand, hvor tværvæggen (112) af U-konsollen (110) er anbragt i en forudbestemt afstand D fra en indre distal overflade af den rørformede forlængelsesdel (22), når drivmidlet er i den forspændte tilstand, hvor den første elastiske del (91) har en første ende (92), der støder an mod den proximale endevæg af stempelstangen (90), og en anden ende (93), der støder an mod en tværvæg (112) af det signalgivende organ (110), hvor et hørligt signal genereres til bekræftelse af, at en lægemiddelafgivelse har fundet sted, når den distale ende af stempelstangen (90) har passeret støtteorganerne (113), således at de langsgående, fleksible arme (111) med støtteorganerne (113) frigøres og kan bevæge sig i en retning radialt indad, hvilket sætter U-konsollen (110) i stand til at bevæge sig den forudbestemte strækning D i den distale retning ved hjælp af en resterende kraft udøvet af det første elastiske del (91), hvorved tværvæggen (112) af konsollen rammer den indre distale overflade på den rørformede forlængelsesdel (22).
2. Lægemiddelafgivelsesindretning (1) ifølge krav 1, i hvilken det rørformede betjeningsorgan (100) omfatter et første samvirkende middel (101,102), som er interaktivt forbundet til et tilsvarende samvirkende middel (35) af det rørformede aktiveringsorgan (30), og et andet samvirkende middel (105), der er interaktivt forbundet til et tilsvarende andet samvirkende middel (121) af den rørformede forlængelsesdel (22); hvor stempelstangen (90) omfatter et løsbart indgrebsmiddel (94), der er interaktivt forbundet med det tilsvarende andet samvirkende middel (121) af den rørformede forlængelsesdel (22), og en proximal endevæg (122), der er i kontakt med den glidbare stopper (83).
3. Lægemiddelafgivelsesindretning (1) ifølge krav 2, i hvilken det andet samvirkende middel (105) omfatter en rille på en indre overflade af det rørformede betjeningsorgan (100), og det tilsvarende andet samvirkende middel (121) af den rørformede forlængelsesdel (22) omfatter en elastisk tunge med et radialt indadrettet fremspring.
4. Lægemiddelafgivelsesindretning (1) ifølge krav 3, i hvilken det løsbare indgrebsmiddel (94) omfatter en rille på en ydre overflade af stempelstangen (90), som er i løsbart indgreb med det radialt indadrettede fremspring på den elastiske tunge (121) beregnet på at holde drivmidlet i den forspændte tilstand.
5. Lægemiddelafgivelsesindretning (1) ifølge krav 4, i hvilken det første samvirkende middel (101,102) omfatter en rille på en ydre overflade af det rørformede betjeningsorgan (100), og det første tilsvarende samvirkende middel (35) omfatter et radialt indadrettet fremspring på den distale ende af den indre overflade af det rørformede aktiveringsorgan (30), således at det radialt indadrettede fremspring (35) er indrettet til at blive ført inde i rillen (101,102) på en ydre overflade af det rørformede betjeningsorgan (100), hvorved det rørformede betjeningsorgan (100) tvinges til at dreje sig, når det rørformede aktiveringsorgan (30) forskydes distalt, hvorved den elastiske tunge (121) bøjes radialt udad ind i rillen (105) på den indre overflade af det rørformede betjeningsorgan (100), og det radialt indadragende fremspring (35) frigøres fra rillen (94) på den ydre overflade af stempelstangen (90), således at drivmidlet frigøres fra den forspændte tilstand.
6. Lægemiddelafgivelsesindretning (1) ifølge ethvert af de foregående krav, i hvilken tværvæggen (112) af U-konsollen (110) omfatter et distalt udragende fremspring, og den distale overflade af det rørformede forlængelsesorgan (22) omfatter et gennemgangshul, således at når tværvæggen (112) af U-konsollen (110) rammer den indre distale overflade af det rørformede forlængelsesorgan (22), vil det distalt udragende fremspring passere gennem gennemgangshullet og strække sig distalt en forudbestemt afstand over den ydre overflade af det rørformede forlængelsesorgan (22) til generering af et føleligt signal.
7. Lægemiddelafgivelsesindretning (1) ifølge krav 6, i hvilken det distalt udragende fremspring har en lys og/eller anden farve end resten af indretningen til generering af et visuelt signal.
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