DK2448963T3 - T-celle receptorer - Google Patents

T-celle receptorer

Info

Publication number: DK2448963T3
Authority: DK; Denmark
Prior art keywords: cell receptors; receptors; cell
Prior art date: 2009-07-03

Application number

DK10734524.1T

Other languages

English (en)

Inventor

Bent Karsten Jakobsen

Naomi Harwood

Nathaniel Ross Liddy

Original Assignee

Immunocore Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-07-03

Filing date

2010-07-01

Publication date

2014-08-25

2010-07-01 Application filed by Immunocore Ltd filed Critical Immunocore Ltd

2014-08-25 Application granted granted Critical

2014-08-25 Publication of DK2448963T3 publication Critical patent/DK2448963T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3053—Skin, nerves, brain
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Cell Biology (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Neurology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicinal Preparation (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK10734524.1T 2009-07-03 2010-07-01 T-celle receptorer DK2448963T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0911566.8A GB0911566D0 (en)	2009-07-03	2009-07-03	T cell receptors
PCT/GB2010/001277 WO2011001152A1 (en)	2009-07-03	2010-07-01	T cell receptors

Publications (1)

Publication Number	Publication Date
DK2448963T3 true DK2448963T3 (da)	2014-08-25

Family

ID=41008692

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK10734524.1T DK2448963T3 (da)	2009-07-03	2010-07-01	T-celle receptorer

Country Status (19)

Country	Link
US (2)	US8519100B2 (da)
EP (1)	EP2448963B1 (da)
JP (2)	JP5872464B2 (da)
CN (3)	CN104017067B (da)
AU (1)	AU2010267758C1 (da)
BR (1)	BR112012000107A2 (da)
CA (1)	CA2766505C (da)
DK (1)	DK2448963T3 (da)
EA (1)	EA026918B1 (da)
ES (1)	ES2498190T3 (da)
FI (1)	FIC20220037I1 (da)
FR (1)	FR22C1046I2 (da)
GB (1)	GB0911566D0 (da)
HK (1)	HK1169422A1 (da)
MX (1)	MX2012000155A (da)
NL (1)	NL301193I2 (da)
PT (1)	PT2448963E (da)
WO (1)	WO2011001152A1 (da)
ZA (1)	ZA201109522B (da)

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2009
- 2009-07-03 GB GBGB0911566.8A patent/GB0911566D0/en not_active Ceased
2010
- 2010-07-01 EA EA201270135A patent/EA026918B1/ru not_active IP Right Cessation
- 2010-07-01 CN CN201410257886.8A patent/CN104017067B/zh active Active
- 2010-07-01 AU AU2010267758A patent/AU2010267758C1/en active Active
- 2010-07-01 EP EP10734524.1A patent/EP2448963B1/en active Active
- 2010-07-01 PT PT107345241T patent/PT2448963E/pt unknown
- 2010-07-01 CN CN2010800351402A patent/CN102574906A/zh active Pending
- 2010-07-01 JP JP2012518126A patent/JP5872464B2/ja active Active
- 2010-07-01 WO PCT/GB2010/001277 patent/WO2011001152A1/en active Application Filing
- 2010-07-01 CA CA2766505A patent/CA2766505C/en active Active
- 2010-07-01 BR BR112012000107A patent/BR112012000107A2/pt not_active Application Discontinuation
- 2010-07-01 ES ES10734524.1T patent/ES2498190T3/es active Active
- 2010-07-01 CN CN201710535038.2A patent/CN107266560A/zh not_active Withdrawn
- 2010-07-01 MX MX2012000155A patent/MX2012000155A/es active IP Right Grant
- 2010-07-01 DK DK10734524.1T patent/DK2448963T3/da active
2011
- 2011-12-22 ZA ZA2011/09522A patent/ZA201109522B/en unknown
2012
- 2012-01-03 US US13/342,579 patent/US8519100B2/en active Active
- 2012-10-16 HK HK12110227.0A patent/HK1169422A1/xx unknown
2013
- 2013-07-22 US US13/947,580 patent/US9068178B2/en active Active
2015
- 2015-10-02 JP JP2015196799A patent/JP6186412B2/ja active Active
2022
- 2022-08-15 NL NL301193C patent/NL301193I2/nl unknown
- 2022-08-31 FI FIC20220037C patent/FIC20220037I1/fi unknown
- 2022-09-02 FR FR22C1046C patent/FR22C1046I2/fr active Active

Also Published As

Publication number	Publication date
PT2448963E (pt)	2014-09-01
CN107266560A (zh)	2017-10-20
EA201270135A1 (ru)	2012-09-28
EP2448963B1 (en)	2014-06-04
EP2448963A1 (en)	2012-05-09
CN104017067B (zh)	2017-11-03
BR112012000107A2 (pt)	2016-11-01
HK1169422A1 (en)	2013-01-25
US20120225481A1 (en)	2012-09-06
US20140099699A1 (en)	2014-04-10
FIC20220037I1 (fi)	2022-08-31
AU2010267758C1 (en)	2015-01-22
US8519100B2 (en)	2013-08-27
US9068178B2 (en)	2015-06-30
AU2010267758A1 (en)	2012-02-09
CN102574906A (zh)	2012-07-11
MX2012000155A (es)	2012-06-28
ES2498190T3 (es)	2014-09-24
JP2016039812A (ja)	2016-03-24
WO2011001152A1 (en)	2011-01-06
AU2010267758B2 (en)	2014-09-04
CN104017067A (zh)	2014-09-03
NL301193I2 (nl)	2022-11-24
FR22C1046I1 (fr)	2022-10-14
CA2766505A1 (en)	2011-01-06
JP6186412B2 (ja)	2017-08-23
CA2766505C (en)	2019-01-22
EA026918B1 (ru)	2017-05-31
GB0911566D0 (en)	2009-08-12
JP5872464B2 (ja)	2016-03-01
NL301193I1 (da)	2022-08-17
FR22C1046I2 (fr)	2025-04-04
JP2012531904A (ja)	2012-12-13
ZA201109522B (en)	2013-05-29

Publication	Publication Date	Title
FR22C1046I2 (fr)	2025-04-04	Recepteurs des cellules t
BRPI1010035A2 (pt)	2015-08-25	Células deficientes em fucosilação
ZA201300621B (en)	2014-06-25	T cell receptors
DK2411442T4 (da)	2021-12-06	Umættet polyesterresin
DE112010004215A5 (de)	2012-08-23	Hydrostataktor
DE112010002949A5 (de)	2012-09-06	Kupplungstastpunkte
BRPI1008827A2 (pt)	2016-02-23	deisobutenizador
BRPI1014968A2 (pt)	2016-12-13	subalargador
BR112012000657A2 (pt)	2016-11-16	novos azabicilohexanos
DE112010002728A5 (de)	2012-06-21	Turboinhalator
DE112010004249A5 (de)	2012-11-29	Spindelaktor
DE112009005323A5 (de)	2012-07-26	Hebelarmprüfmaschine
DE112009005462T8 (de)	2013-03-28	Lenkungsssteuervorrichtung
BR112012004964A2 (pt)	2016-04-05	girocóptero
BRPI1008070A2 (pt)	2016-03-15	tricianoboratos
EP2508411A4 (en)	2013-05-08	STRUCTURE
DE112010004865T8 (de)	2013-01-24	Lamellennassreibkupplung
DE112010003255A5 (de)	2013-05-02	Fördergutverteiler
BRPI1010159A2 (pt)	2016-03-29	bistuti
EP2395565A4 (en)	2013-09-18	SOLAR CELL
EP2432059A4 (en)	2014-02-12	Fuel cell
DE602010000025D1 (de)	2011-06-09	Fahrzeugsitzgurtvorrichtung
BR112012003616A2 (pt)	2016-02-23	metilpirroloprimidinacarboxamidas
DE112010002351A5 (de)	2012-08-09	Klemmorrichtung
DE112010003843T8 (de)	2012-11-29	Lastansteuervorrichtung