DK1987159T4 - Fremgangsmåde til sekventering af en polynukleotidtemplate - Google Patents
Fremgangsmåde til sekventering af en polynukleotidtemplate Download PDFInfo
- Publication number
- DK1987159T4 DK1987159T4 DK07705178.7T DK07705178T DK1987159T4 DK 1987159 T4 DK1987159 T4 DK 1987159T4 DK 07705178 T DK07705178 T DK 07705178T DK 1987159 T4 DK1987159 T4 DK 1987159T4
- Authority
- DK
- Denmark
- Prior art keywords
- polynucleotid
- template
- procedure
- sequence
- polynucleotid template
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77136106P | 2006-02-08 | 2006-02-08 | |
PCT/GB2007/000447 WO2007091077A1 (en) | 2006-02-08 | 2007-02-08 | Method for sequencing a polynucleotide template |
Publications (2)
Publication Number | Publication Date |
---|---|
DK1987159T3 DK1987159T3 (da) | 2012-12-10 |
DK1987159T4 true DK1987159T4 (da) | 2020-11-16 |
Family
ID=37969705
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07705178.7T DK1987159T4 (da) | 2006-02-08 | 2007-02-08 | Fremgangsmåde til sekventering af en polynukleotidtemplate |
Country Status (7)
Country | Link |
---|---|
US (4) | US8192930B2 (da) |
EP (1) | EP1987159B2 (da) |
CN (1) | CN101415839B (da) |
CA (1) | CA2641851A1 (da) |
DK (1) | DK1987159T4 (da) |
SG (1) | SG169356A1 (da) |
WO (1) | WO2007091077A1 (da) |
Families Citing this family (88)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE510024T1 (de) | 2003-10-31 | 2011-06-15 | Advanced Genetic Analysis Corp Ab | Verfahren zur herstellung eines gepaarten tag aus einer nukleinsäuresequenz sowie verfahren zur verwendung davon |
AU2006259565B2 (en) | 2005-06-15 | 2011-01-06 | Complete Genomics, Inc. | Single molecule arrays for genetic and chemical analysis |
GB0514910D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Method for sequencing a polynucleotide template |
GB0514935D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Methods for sequencing a polynucleotide template |
DE602007009634D1 (de) * | 2006-01-04 | 2010-11-18 | Si Lok | Verfahren zur zuordnung von nukleinsäuren und zur identifikation fein strukturierter variationen in nukleinsäuren sowie hilfsmittel dafür |
CN101415839B (zh) | 2006-02-08 | 2012-06-27 | 亿明达剑桥有限公司 | 对多核苷酸模板进行测序的方法 |
US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
EP2191011B1 (en) * | 2007-08-29 | 2017-03-29 | Illumina Cambridge Limited | Method for sequencing a polynucleotide template |
EP2201021A4 (en) * | 2007-08-29 | 2012-01-25 | Applied Biosystems Llc | METHOD OF ALTERNATING NUCLEIC ACID SEQUENCING |
US8592150B2 (en) | 2007-12-05 | 2013-11-26 | Complete Genomics, Inc. | Methods and compositions for long fragment read sequencing |
WO2009089384A1 (en) | 2008-01-09 | 2009-07-16 | Life Technologies | Method of making a paired tag library for nucleic acid sequencing |
US9540637B2 (en) | 2008-01-09 | 2017-01-10 | Life Technologies Corporation | Nucleic acid adaptors and uses thereof |
US8263367B2 (en) | 2008-01-25 | 2012-09-11 | Agency For Science, Technology And Research | Nucleic acid interaction analysis |
US8202691B2 (en) | 2008-01-25 | 2012-06-19 | Illumina, Inc. | Uniform fragmentation of DNA using binding proteins |
US12060554B2 (en) | 2008-03-10 | 2024-08-13 | Illumina, Inc. | Method for selecting and amplifying polynucleotides |
US9074244B2 (en) * | 2008-03-11 | 2015-07-07 | Affymetrix, Inc. | Array-based translocation and rearrangement assays |
WO2010048337A2 (en) | 2008-10-22 | 2010-04-29 | Illumina, Inc. | Preservation of information related to genomic dna methylation |
US8993230B2 (en) * | 2008-12-04 | 2015-03-31 | Pacific Biosciences of Californ, Inc. | Asynchronous sequencing of biological polymers |
US9334531B2 (en) | 2010-12-17 | 2016-05-10 | Life Technologies Corporation | Nucleic acid amplification |
US9309557B2 (en) | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Nucleic acid amplification |
WO2011011175A2 (en) | 2009-07-24 | 2011-01-27 | Illumina, Inc. | Method for sequencing a polynucleotide template |
EP2470669B1 (en) | 2009-08-25 | 2014-06-18 | Illumina, Inc. | Methods for selecting and amplifying polynucleotides |
US10072287B2 (en) | 2009-09-10 | 2018-09-11 | Centrillion Technology Holdings Corporation | Methods of targeted sequencing |
US10174368B2 (en) | 2009-09-10 | 2019-01-08 | Centrillion Technology Holdings Corporation | Methods and systems for sequencing long nucleic acids |
EP2510126B1 (en) * | 2009-12-07 | 2017-08-09 | Illumina, Inc. | Multi-sample indexing for multiplex genotyping |
EP2390350A1 (en) * | 2010-05-27 | 2011-11-30 | Centre National de la Recherche Scientifique (CNRS) | Method of DNA sequencing by polymerisation |
US9029103B2 (en) | 2010-08-27 | 2015-05-12 | Illumina Cambridge Limited | Methods for sequencing polynucleotides |
US8483969B2 (en) | 2010-09-17 | 2013-07-09 | Illuminia, Inc. | Variation analysis for multiple templates on a solid support |
WO2012050920A1 (en) | 2010-09-29 | 2012-04-19 | Illumina, Inc. | Compositions and methods for sequencing nucleic acids |
CN110079588B (zh) | 2010-12-17 | 2024-03-15 | 生命技术公司 | 用于核酸扩增的方法、组合物、系统、仪器和试剂盒 |
US20120252682A1 (en) * | 2011-04-01 | 2012-10-04 | Maples Corporate Services Limited | Methods and systems for sequencing nucleic acids |
US20150011396A1 (en) | 2012-07-09 | 2015-01-08 | Benjamin G. Schroeder | Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing |
US9092401B2 (en) | 2012-10-31 | 2015-07-28 | Counsyl, Inc. | System and methods for detecting genetic variation |
EP3260554B1 (en) * | 2012-08-24 | 2019-07-31 | Life Technologies Corporation | Methods, compositions, systems, apparatuses and kits for nucleic acid paired end sequencing |
US9181583B2 (en) | 2012-10-23 | 2015-11-10 | Illumina, Inc. | HLA typing using selective amplification and sequencing |
WO2014160254A2 (en) * | 2013-03-14 | 2014-10-02 | Abbott Molecular Inc. | Minimizing errors using uracil-dna-n-glycosylase |
US9255265B2 (en) | 2013-03-15 | 2016-02-09 | Illumina, Inc. | Methods for producing stranded cDNA libraries |
US9822408B2 (en) | 2013-03-15 | 2017-11-21 | Nugen Technologies, Inc. | Sequential sequencing |
AU2014284584B2 (en) * | 2013-07-01 | 2019-08-01 | Illumina, Inc. | Catalyst-free surface functionalization and polymer grafting |
EP3017063B1 (en) | 2013-07-03 | 2017-04-05 | Illumina, Inc. | Sequencing by orthogonal synthesis |
EP3227461A1 (en) | 2014-12-05 | 2017-10-11 | Amyris, Inc. | High-throughput sequencing of polynucleotides |
ES2789349T3 (es) | 2015-05-29 | 2020-10-26 | Illumina Cambridge Ltd | Utilización mejorada de cebadores de superficie en grupos |
DK3329007T3 (da) | 2015-07-30 | 2021-04-26 | Illumina Inc | Ortogonal afblokering af nukleotider |
CN106434856B (zh) * | 2015-08-06 | 2020-02-07 | 深圳华大智造科技有限公司 | 一种测序仪运行测试的方法 |
EP3448868B1 (en) * | 2016-04-27 | 2021-12-29 | Bio-Rad Laboratories, Inc. | Mirna transcriptome methods and compositions |
JP6915939B2 (ja) * | 2016-04-29 | 2021-08-11 | オムニオム インコーポレイテッドOmniome, Inc. | 核酸配列決定方法 |
US10597643B2 (en) | 2016-04-29 | 2020-03-24 | Omniome, Inc. | Polymerases engineered to reduce nucleotide-independent DNA binding |
WO2018035134A1 (en) * | 2016-08-15 | 2018-02-22 | Omniome, Inc. | Method and system for sequencing nucleic acids |
AU2017371498B2 (en) * | 2016-12-09 | 2020-10-01 | Regeneron Pharmaceuticals, Inc. | Systems and methods for sequencing T cell receptors and uses thereof |
US20210072255A1 (en) | 2016-12-16 | 2021-03-11 | The Brigham And Women's Hospital, Inc. | System and method for protein corona sensor array for early detection of diseases |
CA3049722C (en) * | 2017-01-10 | 2023-01-24 | Omniome, Inc. | Polymerases engineered to reduce nucleotide-independent dna binding |
US10415029B2 (en) | 2017-01-20 | 2019-09-17 | Omniome, Inc. | Allele-specific capture of nucleic acids |
AU2017394645B2 (en) * | 2017-01-20 | 2020-01-23 | Pacific Biosciences Of California, Inc. | Genotyping by polymerase binding |
US9932631B1 (en) | 2017-09-11 | 2018-04-03 | Omniome, Inc. | Genotyping by polymerase binding |
US10161003B2 (en) | 2017-04-25 | 2018-12-25 | Omniome, Inc. | Methods and apparatus that increase sequencing-by-binding efficiency |
US9951385B1 (en) | 2017-04-25 | 2018-04-24 | Omniome, Inc. | Methods and apparatus that increase sequencing-by-binding efficiency |
CA3118666A1 (en) | 2018-11-07 | 2020-05-14 | Seer, Inc. | Compositions, methods and systems for protein corona analysis and uses thereof |
JP7569690B2 (ja) | 2018-12-05 | 2024-10-18 | イルミナ ケンブリッジ リミテッド | ブリッジ増幅によるクラスタ生成のための方法および組成物 |
JP7587425B2 (ja) | 2018-12-18 | 2024-11-20 | イルミナ ケンブリッジ リミテッド | 単一表面プライマーを使用したペアエンドシーケンシングのための方法および組成物 |
EP3947726A1 (en) | 2019-04-03 | 2022-02-09 | Agilent Technologies, Inc. | Compositions and methods for identifying and characterizing gene translocations, rearrangements and inversions |
US20200377937A1 (en) * | 2019-05-03 | 2020-12-03 | Ultima Genomics, Inc. | Fast-forward sequencing by synthesis methods |
US20210017596A1 (en) * | 2019-05-08 | 2021-01-21 | Qiagen Sciences, Llc | Sequential sequencing methods and compositions |
CN114651058B (zh) | 2019-08-05 | 2023-07-28 | 禧尔公司 | 用于样品制备、数据生成和蛋白质冠分析的系统和方法 |
TW202120693A (zh) * | 2019-08-21 | 2021-06-01 | 美商伊路米納有限公司 | 偵測核苷酸之聚合酶併入的方法 |
US12059674B2 (en) | 2020-02-03 | 2024-08-13 | Tecan Genomics, Inc. | Reagent storage system |
EP4114966B1 (en) | 2020-03-03 | 2025-02-26 | Pacific Biosciences Of California, Inc. | Methods and compositions for sequencing double stranded nucleic acids |
CA3145445A1 (en) | 2020-03-09 | 2021-09-16 | Illumina, Inc. | Methods for sequencing polynucleotides |
DE112021004478T5 (de) | 2020-08-25 | 2023-09-14 | Seer, Inc. | Zusammensetzungen und verfahren zur bestimmung von proteinen und nukleinsäuren |
US20220082569A1 (en) * | 2020-09-11 | 2022-03-17 | Illumina, Inc. | Detecting elements using sugar-lectin couplings |
WO2022099271A1 (en) * | 2020-11-04 | 2022-05-12 | Ultima Genomics, Inc. | Methods and systems for determining sequencing read distances |
US11427855B1 (en) | 2021-06-17 | 2022-08-30 | Element Biosciences, Inc. | Compositions and methods for pairwise sequencing |
US11859241B2 (en) | 2021-06-17 | 2024-01-02 | Element Biosciences, Inc. | Compositions and methods for pairwise sequencing |
CA3223595A1 (en) | 2021-12-16 | 2023-06-22 | Xiaoyu Ma | Hybrid clustering |
WO2023114394A1 (en) | 2021-12-17 | 2023-06-22 | Illumina, Inc. | Orthogonal hybridization |
WO2023175040A2 (en) | 2022-03-15 | 2023-09-21 | Illumina, Inc. | Concurrent sequencing of forward and reverse complement strands on concatenated polynucleotides for methylation detection |
WO2023175041A1 (en) | 2022-03-15 | 2023-09-21 | Illumina, Inc. | Concurrent sequencing of forward and reverse complement strands on concatenated polynucleotides |
US20240124916A1 (en) | 2022-09-16 | 2024-04-18 | Illumina Cambridge Limited | Nanoparticle with polynucleotide binding site and method of making thereof |
WO2024061799A1 (en) | 2022-09-19 | 2024-03-28 | Illumina, Inc. | Deformable polymers comprising immobilised primers |
US20240102067A1 (en) | 2022-09-26 | 2024-03-28 | Illumina, Inc. | Resynthesis Kits and Methods |
US20240124914A1 (en) | 2022-09-30 | 2024-04-18 | Illumina, Inc. | Thermophilic compositions for nucleic acid amplification |
US20240110234A1 (en) | 2022-09-30 | 2024-04-04 | Illumina, Inc. | Amplification Compositions and Methods |
US20240124929A1 (en) | 2022-09-30 | 2024-04-18 | Illumina, Inc. | Mesophilic compositions for nucleic acid amplification |
US20240110221A1 (en) | 2022-09-30 | 2024-04-04 | Illumina, Inc. | Methods of modulating clustering kinetics |
WO2024256580A1 (en) | 2023-06-14 | 2024-12-19 | Illumina, Inc. | Concurrent sequencing with spatially separated rings |
WO2024256581A1 (en) | 2023-06-14 | 2024-12-19 | Illumina, Inc. | Determination of modified cytosines |
WO2025062001A1 (en) | 2023-09-20 | 2025-03-27 | Illumina, Inc. | Optimised nucleic acid sequencing |
WO2025062002A1 (en) | 2023-09-20 | 2025-03-27 | Illumina, Inc. | Concurrent sequencing using nick translation |
WO2025072683A1 (en) | 2023-09-29 | 2025-04-03 | Illumina, Inc. | Solid supports and methods for strand invasion-based amplification |
Family Cites Families (86)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB205153A (en) | 1922-07-04 | 1923-10-04 | Charles Ashton Henry Bullock | Improvements in type setting apparatus |
US4292503A (en) | 1979-05-14 | 1981-09-29 | Emerson Electric Co. | Split-band electric heater |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
EP0224126A3 (en) | 1985-11-25 | 1989-02-01 | The University of Calgary | Covalently linked complementary oligodeoxynucleotides as universal nucleic acid sequencing primer linkers |
US6270961B1 (en) | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
IE72468B1 (en) | 1987-07-31 | 1997-04-09 | Univ Leland Stanford Junior | Selective amplification of target polynucleotide sequences |
SE8801070D0 (sv) | 1988-03-23 | 1988-03-23 | Pharmacia Ab | Method for immobilizing a dna sequence on a solid support |
US6107023A (en) | 1988-06-17 | 2000-08-22 | Genelabs Technologies, Inc. | DNA amplification and subtraction techniques |
GB8818020D0 (en) | 1988-07-28 | 1988-09-01 | Ici Plc | Method for amplification of nucleotide sequences |
US5512439A (en) | 1988-11-21 | 1996-04-30 | Dynal As | Oligonucleotide-linked magnetic particles and uses thereof |
CA2004326A1 (en) | 1988-12-23 | 1990-06-23 | Nanibushan Dattagupta | Assay of sequences using amplified genes |
US5629158A (en) | 1989-03-22 | 1997-05-13 | Cemu Bitecknik Ab | Solid phase diagnosis of medical conditions |
US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
US5547839A (en) | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
US5302509A (en) | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
JP3096722B2 (ja) | 1990-01-17 | 2000-10-10 | 日本ケミカルリサーチ株式会社 | ポリメラーゼ・チェーン・リアクション用プライマーの作製法およびそれを用いるdnaの増幅法 |
US5118604A (en) | 1990-06-15 | 1992-06-02 | Yale University | Restriction-fragment DNA probes and probe clusters |
WO1993004199A2 (en) | 1991-08-20 | 1993-03-04 | Scientific Generics Limited | Methods of detecting or quantitating nucleic acids and of producing labelled immobilised nucleic acids |
DK0969102T3 (da) | 1991-09-24 | 2008-05-13 | Keygene Nv | Primere, kits og sæt af restriktionsfragmenter anvendt ved selektiv restriktionsfragmentamplifikation |
AU3728093A (en) | 1992-02-19 | 1993-09-13 | Public Health Research Institute Of The City Of New York, Inc., The | Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids |
DE69327326T2 (de) | 1992-07-24 | 2001-08-16 | Diatech Pty. Ltd., Brisbane | Vervielfältigungs- und detektionsprozess |
RU2048522C1 (ru) | 1992-10-14 | 1995-11-20 | Институт белка РАН | Способ размножения нуклеиновых кислот, способ их экспрессии и среда для их осуществления |
JPH07203998A (ja) | 1994-01-26 | 1995-08-08 | Hamamatsu Photonics Kk | 核酸塩基配列決定方法 |
EP0763135B1 (en) | 1994-05-28 | 2002-07-10 | Tepnel Medical Limited | Producing copies of nucleic acids |
US5641658A (en) | 1994-08-03 | 1997-06-24 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid with two primers bound to a single solid support |
US6090592A (en) | 1994-08-03 | 2000-07-18 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid on supports |
US6060288A (en) | 1994-08-03 | 2000-05-09 | Mosaic Technologies | Method for performing amplification of nucleic acid on supports |
AU5544696A (en) | 1995-04-11 | 1996-10-30 | Trustees Of Boston University | Solid phase sequencing of biopolymers |
DE19515552A1 (de) * | 1995-04-27 | 1996-10-31 | Europ Lab Molekularbiolog | Simultane Sequenzierung von Nukleinsäuren |
SE9504099D0 (sv) | 1995-11-16 | 1995-11-16 | Pharmacia Biotech Ab | A method of sequencing |
EP0923650B1 (en) * | 1996-06-06 | 2007-03-07 | Solexa, Inc | Sequencing by ligation of encoded adaptors |
US5935788A (en) | 1996-06-25 | 1999-08-10 | Lifespan Biosciences, Inc. | Subtractive hybridization techniques for identifying differentially expressed and commonly expressed nucleic acid |
US5837466A (en) | 1996-12-16 | 1998-11-17 | Vysis, Inc. | Devices and methods for detecting nucleic acid analytes in samples |
US20020061532A1 (en) | 1997-02-14 | 2002-05-23 | Mosaic Technologies, Inc. | Method and apparatus for performing amplification of nucleic acids on supports |
EP0975802B1 (en) | 1997-04-01 | 2004-06-23 | Manteia S.A. | Method of nucleic acid sequencing |
EP3034626A1 (en) | 1997-04-01 | 2016-06-22 | Illumina Cambridge Limited | Method of nucleic acid sequencing |
US6326489B1 (en) | 1997-08-05 | 2001-12-04 | Howard Hughes Medical Institute | Surface-bound, bimolecular, double-stranded DNA arrays |
US6087099A (en) | 1997-09-08 | 2000-07-11 | Myriad Genetics, Inc. | Method for sequencing both strands of a double stranded DNA in a single sequencing reaction |
US6511803B1 (en) | 1997-10-10 | 2003-01-28 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
US20030022207A1 (en) | 1998-10-16 | 2003-01-30 | Solexa, Ltd. | Arrayed polynucleotides and their use in genome analysis |
AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
AU2144000A (en) | 1998-10-27 | 2000-05-15 | Affymetrix, Inc. | Complexity management and analysis of genomic dna |
US20030108867A1 (en) | 1999-04-20 | 2003-06-12 | Chee Mark S | Nucleic acid sequencing using microsphere arrays |
US6521428B1 (en) | 1999-04-21 | 2003-02-18 | Genome Technologies, Llc | Shot-gun sequencing and amplification without cloning |
US6300070B1 (en) | 1999-06-04 | 2001-10-09 | Mosaic Technologies, Inc. | Solid phase methods for amplifying multiple nucleic acids |
US6339147B1 (en) * | 1999-07-29 | 2002-01-15 | Epoch Biosciences, Inc. | Attachment of oligonucleotides to solid supports through Schiff base type linkages for capture and detection of nucleic acids |
DE10051564A1 (de) | 2000-10-18 | 2002-08-01 | Axaron Bioscience Ag | Neue Verfahren zur parallelen Sequenzierung eines Nukleinsäuregemisches an einer Oberfläche |
EP1242630B1 (en) | 1999-12-29 | 2006-02-01 | Keygene N.V. | Method for generating oligonucleotides, in particular for the detection of amplified restriction fragments obtained using aflp |
AU2001251582A1 (en) | 2000-04-14 | 2001-10-30 | Lynx Therapeutics, Inc. | Method and compositions for ordering restriction fragments |
AR031640A1 (es) | 2000-12-08 | 2003-09-24 | Applied Research Systems | Amplificacion isotermica de acidos nucleicos en un soporte solido |
EP1256632A3 (en) | 2001-05-07 | 2004-01-02 | Smithkline Beecham Corporation | High throughput polymorphism screening |
GB0112238D0 (en) * | 2001-05-18 | 2001-07-11 | Medical Biosystems Ltd | Sequencing method |
US20030219770A1 (en) | 2001-11-08 | 2003-11-27 | Eshleman James R. | Methods and systems of nucleic acid sequencing |
CA2478722A1 (en) | 2002-03-05 | 2003-09-12 | Solexa Limited | Methods for detecting genome-wide sequence variations associated with a phenotype |
US20040002090A1 (en) | 2002-03-05 | 2004-01-01 | Pascal Mayer | Methods for detecting genome-wide sequence variations associated with a phenotype |
GB0205153D0 (en) | 2002-03-05 | 2002-04-17 | Manteia S A | Methods for detecting genome-wide sequence variations associated with a phenotype |
US20040126765A1 (en) | 2002-12-27 | 2004-07-01 | Adams Craig W. | Method and compositions for sequencing nucleic acid molecules |
CN101128601B (zh) | 2003-01-29 | 2011-06-08 | 454生命科学公司 | 核酸扩增和测序的方法 |
CA2515938A1 (en) | 2003-02-12 | 2004-08-26 | Genizon Svenska Ab | Methods and means for nucleic acid sequencing |
AU2004214891B2 (en) | 2003-02-26 | 2010-01-07 | Complete Genomics, Inc. | Random array DNA analysis by hybridization |
GB0324456D0 (en) | 2003-10-20 | 2003-11-19 | Isis Innovation | Parallel DNA sequencing methods |
ATE510024T1 (de) | 2003-10-31 | 2011-06-15 | Advanced Genetic Analysis Corp Ab | Verfahren zur herstellung eines gepaarten tag aus einer nukleinsäuresequenz sowie verfahren zur verwendung davon |
GB0400584D0 (en) | 2004-01-12 | 2004-02-11 | Solexa Ltd | Nucleic acid chacterisation |
AU2005216549A1 (en) | 2004-02-27 | 2005-09-09 | President And Fellows Of Harvard College | Polony fluorescent in situ sequencing beads |
AU2005222788A1 (en) | 2004-02-27 | 2005-09-29 | President And Fellows Of Harvard College | Polynucleotide synthesis |
GB2412170A (en) | 2004-03-16 | 2005-09-21 | Plant Bioscience Ltd | A method for enriching for target nucleic acids in a sample |
GB2413796B (en) | 2004-03-25 | 2006-03-29 | Global Genomics Ab | Methods and means for nucleic acid sequencing |
WO2006073504A2 (en) | 2004-08-04 | 2006-07-13 | President And Fellows Of Harvard College | Wobble sequencing |
US20060078899A1 (en) | 2004-10-12 | 2006-04-13 | Scheffer Alicia F | Methods and compositions for reducing label variation in array-based comparative genome hybridization assays |
WO2006110855A2 (en) | 2005-04-12 | 2006-10-19 | 454 Life Sciences Corporation | Methods for determining sequence variants using ultra-deep sequencing |
US7601499B2 (en) | 2005-06-06 | 2009-10-13 | 454 Life Sciences Corporation | Paired end sequencing |
US8428882B2 (en) | 2005-06-14 | 2013-04-23 | Agency For Science, Technology And Research | Method of processing and/or genome mapping of diTag sequences |
GB0514910D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Method for sequencing a polynucleotide template |
GB0514935D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Methods for sequencing a polynucleotide template |
GB0514936D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Preparation of templates for nucleic acid sequencing |
US7960104B2 (en) | 2005-10-07 | 2011-06-14 | Callida Genomics, Inc. | Self-assembled single molecule arrays and uses thereof |
GB0522310D0 (en) | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
DE602007009634D1 (de) | 2006-01-04 | 2010-11-18 | Si Lok | Verfahren zur zuordnung von nukleinsäuren und zur identifikation fein strukturierter variationen in nukleinsäuren sowie hilfsmittel dafür |
CN101415839B (zh) | 2006-02-08 | 2012-06-27 | 亿明达剑桥有限公司 | 对多核苷酸模板进行测序的方法 |
WO2007107710A1 (en) | 2006-03-17 | 2007-09-27 | Solexa Limited | Isothermal methods for creating clonal single molecule arrays |
US20070231823A1 (en) | 2006-03-23 | 2007-10-04 | Mckernan Kevin J | Directed enrichment of genomic DNA for high-throughput sequencing |
WO2008002502A2 (en) | 2006-06-23 | 2008-01-03 | Illumina, Inc. | Devices and systems for creation of dna cluster arrays |
US7754429B2 (en) * | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
WO2008070352A2 (en) | 2006-10-27 | 2008-06-12 | Complete Genomics, Inc. | Efficient arrays of amplified polynucleotides |
EP2121983A2 (en) * | 2007-02-02 | 2009-11-25 | Illumina Cambridge Limited | Methods for indexing samples and sequencing multiple nucleotide templates |
EP2191011B1 (en) | 2007-08-29 | 2017-03-29 | Illumina Cambridge Limited | Method for sequencing a polynucleotide template |
-
2007
- 2007-02-08 CN CN2007800102959A patent/CN101415839B/zh active Active
- 2007-02-08 SG SG201100634-3A patent/SG169356A1/en unknown
- 2007-02-08 WO PCT/GB2007/000447 patent/WO2007091077A1/en active Application Filing
- 2007-02-08 DK DK07705178.7T patent/DK1987159T4/da active
- 2007-02-08 EP EP07705178.7A patent/EP1987159B2/en active Active
- 2007-02-08 US US12/223,759 patent/US8192930B2/en active Active
- 2007-02-08 CA CA002641851A patent/CA2641851A1/en not_active Abandoned
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2012
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US20110009276A1 (en) | 2011-01-13 |
CA2641851A1 (en) | 2007-08-16 |
US10876158B2 (en) | 2020-12-29 |
EP1987159A1 (en) | 2008-11-05 |
US20130165327A1 (en) | 2013-06-27 |
EP1987159B2 (en) | 2020-08-12 |
EP1987159B1 (en) | 2012-09-12 |
WO2007091077A1 (en) | 2007-08-16 |
CN101415839A (zh) | 2009-04-22 |
US8945835B2 (en) | 2015-02-03 |
CN101415839B (zh) | 2012-06-27 |
US20150203910A1 (en) | 2015-07-23 |
US8192930B2 (en) | 2012-06-05 |
DK1987159T3 (da) | 2012-12-10 |
US20180363047A1 (en) | 2018-12-20 |
US9994896B2 (en) | 2018-06-12 |
SG169356A1 (en) | 2011-03-30 |
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