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DK1907408T3 - Stabile NAD/NADH-derivater - Google Patents

Stabile NAD/NADH-derivater

Info

Publication number
DK1907408T3
DK1907408T3 DK06776486.0T DK06776486T DK1907408T3 DK 1907408 T3 DK1907408 T3 DK 1907408T3 DK 06776486 T DK06776486 T DK 06776486T DK 1907408 T3 DK1907408 T3 DK 1907408T3
Authority
DK
Denmark
Prior art keywords
stable nad
nadh derivatives
nadh
derivatives
nad
Prior art date
Application number
DK06776486.0T
Other languages
English (en)
Inventor
Joachim Hoenes
Dieter Heindl
Carina Horn
Claudia Gaessler-Dietsche
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1907408T3 publication Critical patent/DK1907408T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK06776486.0T 2005-07-28 2006-07-28 Stabile NAD/NADH-derivater DK1907408T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005035461A DE102005035461A1 (de) 2005-07-28 2005-07-28 Stabile NAD/NADH-Derivate
PCT/EP2006/007493 WO2007012494A1 (de) 2005-07-28 2006-07-28 Stabile nad/nadh-derivate

Publications (1)

Publication Number Publication Date
DK1907408T3 true DK1907408T3 (da) 2014-06-10

Family

ID=37137552

Family Applications (3)

Application Number Title Priority Date Filing Date
DK11167471.9T DK2364988T3 (da) 2005-07-28 2006-07-28 Stabile NAD/NADH-derivater
DK06776486.0T DK1907408T3 (da) 2005-07-28 2006-07-28 Stabile NAD/NADH-derivater
DK11167476.8T DK2364989T3 (da) 2005-07-28 2006-07-28 Stabile NAD/NADH-derivater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK11167471.9T DK2364988T3 (da) 2005-07-28 2006-07-28 Stabile NAD/NADH-derivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK11167476.8T DK2364989T3 (da) 2005-07-28 2006-07-28 Stabile NAD/NADH-derivater

Country Status (17)

Country Link
US (3) US8809013B2 (da)
EP (3) EP1907408B1 (da)
JP (2) JP5129133B2 (da)
KR (4) KR101483899B1 (da)
CN (2) CN101233144B (da)
AU (2) AU2006274140B8 (da)
BR (1) BRPI0614217A2 (da)
CA (2) CA2614792C (da)
DE (1) DE102005035461A1 (da)
DK (3) DK2364988T3 (da)
ES (3) ES2461266T3 (da)
HK (1) HK1123308A1 (da)
MX (1) MX2008000946A (da)
PL (3) PL2364989T3 (da)
PT (3) PT2364989E (da)
SG (1) SG187511A1 (da)
WO (1) WO2007012494A1 (da)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005035461A1 (de) * 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate
US7553615B2 (en) * 2005-07-28 2009-06-30 Roche Diagnostics Operations, Inc. Compounds, methods, complexes, apparatuses and uses relating to stabile forms of NAD/NADH
EP2022859A1 (de) * 2007-08-01 2009-02-11 Roche Diagnostics GmbH Verfahren und Vorrichtung zur Bestimmung der Konzentration eines Analyten mittels Fluoreszenzmessung
CN101497638B (zh) * 2008-01-30 2012-09-26 中国科学院大连化学物理研究所 一种nad+类似物及其合成和应用
EP2093284A1 (de) 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
WO2010094632A1 (de) 2009-02-19 2010-08-26 F. Hoffmann-La Roche Ag Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten
EP2398909B1 (de) 2009-02-19 2015-07-22 F. Hoffmann-La Roche AG Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten
EP2226007A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Testelementmagazin mit abgedeckten Testfeldern
EP2398388B1 (de) * 2009-02-19 2020-04-08 Roche Diabetes Care GmbH Platzsparende magazinierung analytischer hilfsmittel
EP2226008A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Verfahren zur Herstellung eines analytischen Magazins
JP5542931B2 (ja) * 2009-07-27 2014-07-09 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト N置換ピリジニウム化合物の調製のための方法及び物質
JP5544423B2 (ja) 2009-07-27 2014-07-09 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト N置換ピリジニウム化合物の調製のための方法及び物質
EP2459728B1 (en) * 2009-07-27 2013-06-05 Roche Diagnostics GmbH Enzymatic synthesis of carba-NAD
EP2292751A1 (de) 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
EP2287605A1 (de) * 2009-08-20 2011-02-23 Roche Diagnostics GmbH Vereinfachte Magazinierung integrierter Systeme
EP2333544A1 (de) 2009-12-11 2011-06-15 F. Hoffmann-La Roche AG Sterilisierbare Chemie für Testelemente
EP2513648B1 (de) 2009-12-16 2015-05-27 F.Hoffmann-La Roche Ag Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt
KR101252351B1 (ko) * 2010-05-24 2013-04-08 동국대학교 산학협력단 전기효소적 합성 반응을 위한 nad(p) 유도체의 전기화학적 환원 방법
CN102453067B (zh) * 2010-10-29 2015-08-05 中国科学院大连化学物理研究所 一种nad+类似物的制备方法及其应用
EP2668161B1 (en) 2011-01-26 2014-11-26 Roche Diagniostics GmbH Method and substances for preparation of n-substituted pyridinium compounds
MX342218B (es) 2011-04-12 2016-09-21 Hoffmann La Roche Dispositivo analitico.
US9752990B2 (en) 2013-09-30 2017-09-05 Honeywell International Inc. Low-powered system for driving a fuel control mechanism
CN102863495A (zh) * 2011-07-06 2013-01-09 上海执诚生物科技股份有限公司 一种含有nad+或nadh的稳定的组合物
EP2760825B1 (de) 2011-09-28 2016-09-14 F.Hoffmann-La Roche Ag Azomediatoren
JP6128808B2 (ja) * 2011-11-15 2017-05-17 栄研化学株式会社 酵素活性の検出、測定方法およびこれを利用したキット
EP2620507A1 (en) 2012-01-25 2013-07-31 Roche Diagnostics GmbH Method for the evaluation of the quality of a test element
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
KR101728597B1 (ko) 2012-04-19 2017-04-19 에프. 호프만-라 로슈 아게 혈액 내 분석물 농도를 결정하는 방법 및 디바이스
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
US8921061B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
JP6462585B2 (ja) 2012-12-20 2019-01-30 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 医学的測定曲線の評価方法
KR101750638B1 (ko) 2012-12-20 2017-06-23 에프. 호프만-라 로슈 아게 체액의 샘플을 분석하는 방법
EP2770064A1 (de) 2013-02-22 2014-08-27 F. Hoffmann-La Roche AG Hocheffiziente Herstellung von Blutglucose-Teststreifen
EP2781919A1 (en) 2013-03-19 2014-09-24 Roche Diagniostics GmbH Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid
EP2994536B1 (en) 2013-05-08 2017-06-14 Roche Diabetes Care GmbH Stabilization of enzymes by nicotinic acid
CN105247069A (zh) * 2013-06-04 2016-01-13 豪夫迈·罗氏有限公司 用于fret的新化合物及与其相关的方法
EP2811299A1 (en) 2013-06-07 2014-12-10 Roche Diagniostics GmbH Test element for detecting at least one analyte in a body fluid
EP3063169B1 (en) 2013-10-29 2018-10-10 F. Hoffmann-La Roche AG Nano-enzyme containers for test elements
WO2015078899A1 (en) 2013-11-27 2015-06-04 Roche Diagnostics Gmbh Composition comprising up-converting phosphors for detecting an analyte
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
CN106164054B (zh) 2014-04-14 2019-05-07 豪夫迈·罗氏有限公司 吩嗪介导剂
SG11201700876RA (en) * 2014-08-05 2017-03-30 Becton Dickinson Co Methods and compositions for analyzing glucose-6-phosphate dehydrogenase activity in blood samples
JP6659669B2 (ja) 2014-08-22 2020-03-04 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft レドックス指示薬
EP3597765B1 (en) 2014-08-25 2021-06-02 Roche Diagnostics GmbH Interference compensating two electrodes test strip
CN108350439A (zh) 2015-12-21 2018-07-31 豪夫迈·罗氏有限公司 来自粪产碱菌的突变体3-羟基丁酸脱氢酶及其相关方法和用途
EP3414325B1 (en) 2016-02-09 2020-01-29 Roche Diabetes Care GmbH Mutant 3-hydroxybutyrate dehydrogenase from rhodobacter sphaeroides as well as methods and uses involving the same
EP3523639B1 (en) 2016-10-05 2024-12-18 F. Hoffmann-La Roche AG Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same
EP3339431A1 (en) 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
CN107966555A (zh) * 2017-11-23 2018-04-27 中山市创艺生化工程有限公司 一种用于稳定保存nad或其衍生物的存储液
WO2019166394A1 (en) 2018-02-28 2019-09-06 F. Hoffmann-La Roche Ag Biocompatibility coating for continuous analyte measurement
CN111217744A (zh) * 2018-11-26 2020-06-02 中国科学院大连化学物理研究所 一种d-氨基酸基nad+类似物及其合成和应用
CN116648191A (zh) 2020-12-15 2023-08-25 美国雅培糖尿病护理公司 基于nad(p)-依赖酶的传感器的nad(p)储库

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS437333Y1 (da) 1965-07-08 1968-04-01
JPS53107486A (en) * 1977-02-28 1978-09-19 Wako Pure Chem Ind Ltd Stabilized nadh aqueous solution
JPS61274636A (ja) 1985-05-30 1986-12-04 西南自動車工業株式会社 活魚水槽
US5801006A (en) 1997-02-04 1998-09-01 Specialty Assays, Inc. Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
JP4260245B2 (ja) * 1998-06-25 2009-04-30 株式会社三菱化学ヤトロン 還元型ニコチンアミドアデニンジヌクレオチド類の分解を防止する方法及び分解防止用試薬
US6380380B1 (en) 1999-01-04 2002-04-30 Specialty Assays, Inc. Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
WO2001094370A1 (fr) 2000-06-07 2001-12-13 Wako Pure Chemical Industries, Ltd. Derives de coenzymes et enzymes appropries
DE10221845A1 (de) 2002-05-16 2003-11-27 Roche Diagnostics Gmbh Verfahren und Reagenzsystem mit nicht-regenerierbarem Enzym-Coenzym-Komplex
US7341830B2 (en) 2002-05-16 2008-03-11 Roche Diagnostics Operations, Inc. Method and reagent system having a non-regenerative enzyme-coenzyme complex
DE102005035461A1 (de) * 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate

Also Published As

Publication number Publication date
EP2364989B1 (de) 2014-03-05
CN101233144A (zh) 2008-07-30
EP2364989A1 (de) 2011-09-14
CA2614792A1 (en) 2007-02-01
EP2364988A1 (de) 2011-09-14
ES2453150T3 (es) 2014-04-04
MX2008000946A (es) 2008-03-27
CN103122371B (zh) 2016-12-28
CA2737123A1 (en) 2007-02-01
EP1907408B1 (de) 2014-03-05
HK1123308A1 (en) 2009-06-12
KR101483899B1 (ko) 2015-01-16
CN101233144B (zh) 2013-02-06
AU2011200465B2 (en) 2012-02-09
DE102005035461A1 (de) 2007-02-15
CN103122371A (zh) 2013-05-29
KR20120044372A (ko) 2012-05-07
KR20110028522A (ko) 2011-03-18
KR101035524B1 (ko) 2011-05-23
US20080213809A1 (en) 2008-09-04
US8809013B2 (en) 2014-08-19
AU2006274140A1 (en) 2007-02-01
AU2006274140B2 (en) 2010-11-11
AU2006274140B8 (en) 2011-02-03
DK2364989T3 (da) 2014-06-10
PL1907408T3 (pl) 2014-07-31
PT2364989E (pt) 2014-04-04
US9399790B2 (en) 2016-07-26
BRPI0614217A2 (pt) 2011-03-22
PT1907408E (pt) 2014-03-28
PL2364988T3 (pl) 2014-08-29
PT2364988E (pt) 2014-04-03
JP5129133B2 (ja) 2013-01-23
CA2614792C (en) 2011-07-12
DK2364988T3 (da) 2014-05-26
EP1907408A1 (de) 2008-04-09
JP2009502844A (ja) 2009-01-29
EP2364988B1 (de) 2014-02-26
WO2007012494A1 (de) 2007-02-01
JP2012224638A (ja) 2012-11-15
KR20080028507A (ko) 2008-03-31
US20140206024A1 (en) 2014-07-24
AU2011200465A1 (en) 2011-02-24
PL2364989T3 (pl) 2014-08-29
KR101483829B1 (ko) 2015-01-16
US20160326567A1 (en) 2016-11-10
JP5650695B2 (ja) 2015-01-07
WO2007012494B1 (de) 2007-03-29
US10167497B2 (en) 2019-01-01
ES2461624T3 (es) 2014-05-20
SG187511A1 (en) 2013-02-28
KR20140003637A (ko) 2014-01-09
ES2461266T3 (es) 2014-05-19

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