ATE430142T1 - Phenylpiperazin-methanon-derivate - Google Patents
Phenylpiperazin-methanon-derivateInfo
- Publication number
- ATE430142T1 ATE430142T1 AT05817965T AT05817965T ATE430142T1 AT E430142 T1 ATE430142 T1 AT E430142T1 AT 05817965 T AT05817965 T AT 05817965T AT 05817965 T AT05817965 T AT 05817965T AT E430142 T1 ATE430142 T1 AT E430142T1
- Authority
- AT
- Austria
- Prior art keywords
- phenylpiperazine
- methanone derivatives
- methanone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04106440 | 2004-12-09 | ||
| PCT/EP2005/012833 WO2006061135A1 (en) | 2004-12-09 | 2005-12-01 | Phenyl-piperazin methanone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE430142T1 true ATE430142T1 (de) | 2009-05-15 |
Family
ID=36061356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05817965T ATE430142T1 (de) | 2004-12-09 | 2005-12-01 | Phenylpiperazin-methanon-derivate |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US7241761B2 (de) |
| EP (1) | EP1828154B1 (de) |
| JP (1) | JP4762250B2 (de) |
| KR (1) | KR100880093B1 (de) |
| CN (1) | CN101072762B (de) |
| AR (1) | AR054102A1 (de) |
| AT (1) | ATE430142T1 (de) |
| AU (1) | AU2005313581B2 (de) |
| BR (1) | BRPI0518608A2 (de) |
| CA (1) | CA2589192C (de) |
| DE (1) | DE602005014274D1 (de) |
| DK (1) | DK1828154T3 (de) |
| ES (1) | ES2324232T3 (de) |
| HK (1) | HK1114841A1 (de) |
| HR (1) | HRP20090264T1 (de) |
| IL (1) | IL183594A (de) |
| MX (1) | MX2007006429A (de) |
| MY (1) | MY141969A (de) |
| NO (1) | NO20072643L (de) |
| NZ (1) | NZ555290A (de) |
| PL (1) | PL1828154T3 (de) |
| PT (1) | PT1828154E (de) |
| RU (1) | RU2395502C2 (de) |
| SI (1) | SI1828154T1 (de) |
| TW (1) | TWI304064B (de) |
| WO (1) | WO2006061135A1 (de) |
| ZA (1) | ZA200705027B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7485637B2 (en) * | 2005-01-04 | 2009-02-03 | Hoffmann-La Roche Inc. | Benzoyl-tetrahydropiperidine derivatives |
| MX2009009065A (es) * | 2007-03-05 | 2009-08-31 | Hoffmann La Roche | Proceso para sintesis de inhibidores del transportador de glicina 1. |
| AU2011261375B2 (en) * | 2010-06-04 | 2016-09-22 | Albany Molecular Research, Inc. | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
| WO2011163636A2 (en) * | 2010-06-24 | 2011-12-29 | The Regents Of The University Of California | Compounds and uses thereof in modulating levels of various amyloid beta peptide alloforms |
| FR2967674B1 (fr) * | 2010-11-23 | 2012-12-14 | Pf Medicament | Derives d'heteroarylsulfonamides, leur preparation et leur application en therapeutique humaine |
| RU2496495C2 (ru) * | 2011-12-05 | 2013-10-27 | Учреждение Российской академии медицинских наук Научно-исследовательский институт нормальной физиологии имени П.К. Анохина РАМН | ПРИМЕНЕНИЕ СЕЛЕКТИВНОГО АНТАГОНИСТА ГЛУТАМАТНЫХ РЕЦЕПТОРОВ Ro-256981 ДЛЯ НАПРАВЛЕННОГО ВЛИЯНИЯ НА КОГНИТИВНЫЕ ФУНКЦИИ |
| WO2014165263A1 (en) | 2013-03-12 | 2014-10-09 | The Regents Of The University Of California, A California Corporation | Gamma-secretase modulators |
| AU2015338946B2 (en) | 2014-10-31 | 2020-06-11 | The General Hospital Corporation | Potent gamma-secretase modulators |
| CN105712952B (zh) * | 2014-12-22 | 2021-03-26 | 上海翰森生物医药科技有限公司 | 2-取代氧基-5-甲砜基苯基哌嗪酰胺类似物及其制备方法和用途 |
| CN105712945B (zh) * | 2014-12-22 | 2020-12-01 | 上海翰森生物医药科技有限公司 | 2-取代氧基-5-甲砜基芳基哌嗪酰胺类似物及其制备方法和用途 |
| CA3023237A1 (en) * | 2016-05-17 | 2017-11-23 | The Regents Of The University Of California | Piperazinyl methanone naaa inhibitors |
| CN111116573B (zh) * | 2019-12-31 | 2021-08-06 | 中山大学 | 一种双通道下同时检测dna和rna的近红外荧光探针及其制备方法和应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2423847A1 (de) | 1973-05-28 | 1975-01-02 | Ciba Geigy Ag | Neue sulfamoylbenzoesaeureamide |
| DE2611705A1 (de) | 1976-03-18 | 1977-09-22 | Josef Dipl Chem Dr Rer N Klosa | N-5-(nitrofurfuryliden-)-1-amino- hydantoin enthaltende kristalloesungsmittel |
| IT1176613B (it) | 1984-08-14 | 1987-08-18 | Ravizza Spa | Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione |
| RU2124511C1 (ru) | 1993-05-14 | 1999-01-10 | Фармасьютикал Ко., Лтд | Производные пиперазина |
| SK13092000A3 (sk) | 1998-03-06 | 2001-03-12 | Janssen Pharmaceutica N. V. | Inhibítory prenosu glycínu, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie |
| CA2322164A1 (en) * | 1998-03-06 | 1999-09-10 | Ludo Edmond Josephine Kennis | Glycine transport inhibitors |
| AU2001254546A1 (en) | 2000-04-20 | 2001-11-07 | Nps Allelix Corp. | Aminopiperidines |
| GB0021419D0 (en) | 2000-08-31 | 2000-10-18 | Oxford Glycosciences Uk Ltd | Compounds |
| AU2001290786A1 (en) * | 2000-09-14 | 2002-03-26 | Gliatech, Inc. | Nitrogen-containing compounds and their use as glycine transport inhibitors |
| AU2002344951A1 (en) | 2001-07-02 | 2003-01-21 | Boehringer Ingelheim International Gmbh | Substituted piperazine and diazepanes as histamine h3 receptor agonists |
| JP4176633B2 (ja) * | 2001-07-17 | 2008-11-05 | ナームローゼ・フエンノートチヤツプ・オルガノン | Ｎ−［（１−ジメチルアミノシクロアルキル）メチル］ベンズアミド誘導体 |
| WO2003035602A1 (fr) | 2001-10-25 | 2003-05-01 | Sankyo Company, Limited | Modulateurs lipidiques |
| EP1465631B1 (de) * | 2001-12-20 | 2010-02-24 | OSI Pharmaceuticals, Inc. | Selektive pyrimidin-a2b-antagonistenverbindungen, ihre synthese und verwendung |
| AU2003274053A1 (en) | 2002-10-22 | 2004-05-13 | Glaxo Group Limited | Aryloxyalkylamine derivates as h3 receptor ligands |
| PT1594840E (pt) * | 2003-02-17 | 2007-01-31 | Hoffmann La Roche | Derivados de piperidina-benzenossulfonamida |
| GB0314479D0 (en) * | 2003-06-20 | 2003-07-23 | Glaxo Group Ltd | Compounds |
| GB0314476D0 (en) * | 2003-06-20 | 2003-07-23 | Glaxo Group Ltd | Compounds |
| DK1656361T3 (da) | 2003-08-11 | 2008-05-05 | Hoffmann La Roche | Piperazin med OR-substitueret phenylgruppe og anvendelse deraf som GLYT1-inhibitorer |
| PL1703909T3 (pl) | 2003-09-09 | 2009-09-30 | Hoffmann La Roche | Pochodne 1-benzoilopiperazyny jako inhibitory wychwytu glicyny do leczenia psychoz |
| AU2004269889B2 (en) | 2003-09-09 | 2009-07-23 | F. Hoffmann-La Roche Ag | 1- (2-amino-benzol) -piperazine derivatives as glycine uptake inhibitors for the treatment of psychoses |
| FR2861073B1 (fr) | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[heteroaryl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
| GB0408777D0 (en) | 2004-04-20 | 2004-05-26 | Glaxo Group Ltd | Compounds |
| US7572792B2 (en) * | 2004-04-29 | 2009-08-11 | Merck & Co., Inc. | Azetidine glycine transporter inhibitors |
| GB0505086D0 (en) * | 2005-03-11 | 2005-04-20 | Glaxo Group Ltd | Compounds |
-
2005
- 2005-12-01 EP EP05817965A patent/EP1828154B1/de active Active
- 2005-12-01 PT PT05817965T patent/PT1828154E/pt unknown
- 2005-12-01 DK DK05817965T patent/DK1828154T3/da active
- 2005-12-01 DE DE602005014274T patent/DE602005014274D1/de active Active
- 2005-12-01 MX MX2007006429A patent/MX2007006429A/es active IP Right Grant
- 2005-12-01 BR BRPI0518608-0A patent/BRPI0518608A2/pt active Search and Examination
- 2005-12-01 AU AU2005313581A patent/AU2005313581B2/en not_active Ceased
- 2005-12-01 US US11/291,216 patent/US7241761B2/en not_active Expired - Fee Related
- 2005-12-01 RU RU2007120209/04A patent/RU2395502C2/ru not_active IP Right Cessation
- 2005-12-01 WO PCT/EP2005/012833 patent/WO2006061135A1/en active Application Filing
- 2005-12-01 CA CA2589192A patent/CA2589192C/en not_active Expired - Fee Related
- 2005-12-01 SI SI200530699T patent/SI1828154T1/sl unknown
- 2005-12-01 NZ NZ555290A patent/NZ555290A/en not_active IP Right Cessation
- 2005-12-01 AT AT05817965T patent/ATE430142T1/de active
- 2005-12-01 JP JP2007544778A patent/JP4762250B2/ja not_active Expired - Fee Related
- 2005-12-01 KR KR1020077015528A patent/KR100880093B1/ko not_active IP Right Cessation
- 2005-12-01 CN CN2005800421620A patent/CN101072762B/zh not_active Expired - Fee Related
- 2005-12-01 ES ES05817965T patent/ES2324232T3/es active Active
- 2005-12-01 PL PL05817965T patent/PL1828154T3/pl unknown
- 2005-12-06 TW TW094143004A patent/TWI304064B/zh not_active IP Right Cessation
- 2005-12-07 MY MYPI20055721A patent/MY141969A/en unknown
- 2005-12-07 AR ARP050105107A patent/AR054102A1/es not_active Application Discontinuation
-
2007
- 2007-05-21 US US11/804,955 patent/US7429585B2/en not_active Expired - Fee Related
- 2007-05-24 NO NO20072643A patent/NO20072643L/no not_active Application Discontinuation
- 2007-05-31 IL IL183594A patent/IL183594A/en not_active IP Right Cessation
- 2007-06-04 ZA ZA200705027A patent/ZA200705027B/xx unknown
-
2008
- 2008-04-29 HK HK08104729.2A patent/HK1114841A1/xx not_active IP Right Cessation
-
2009
- 2009-05-12 HR HR20090264T patent/HRP20090264T1/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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