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DK1764368T3 - Antimototisk halogeneret derivat af vincaalkaloid - Google Patents

Antimototisk halogeneret derivat af vincaalkaloid

Info

Publication number
DK1764368T3
DK1764368T3 DK06124480.2T DK06124480T DK1764368T3 DK 1764368 T3 DK1764368 T3 DK 1764368T3 DK 06124480 T DK06124480 T DK 06124480T DK 1764368 T3 DK1764368 T3 DK 1764368T3
Authority
DK
Denmark
Prior art keywords
vinca alkaloid
antimototic
halogenated derivative
formula
preparation
Prior art date
Application number
DK06124480.2T
Other languages
English (en)
Inventor
Jacques Fahy
Jean-Marc Barret
Bridget Hill
Alain Duflos
Du Boullay Valerie Thillaye
Original Assignee
Pierre Fabre Medicament Produc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament Produc filed Critical Pierre Fabre Medicament Produc
Application granted granted Critical
Publication of DK1764368T3 publication Critical patent/DK1764368T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK06124480.2T 1997-04-10 1998-04-10 Antimototisk halogeneret derivat af vincaalkaloid DK1764368T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9704398A FR2761990B1 (fr) 1997-04-10 1997-04-10 Derives halogenes antimitotiques d'alcaloides de vinca
EP20030017052 EP1357125A3 (fr) 1997-04-10 1998-04-10 Procédé de préparation de dérivés halogénés d'alcaloides de vinca

Publications (1)

Publication Number Publication Date
DK1764368T3 true DK1764368T3 (da) 2010-10-18

Family

ID=9505731

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06124480.2T DK1764368T3 (da) 1997-04-10 1998-04-10 Antimototisk halogeneret derivat af vincaalkaloid
DK98920607T DK0975640T3 (da) 1997-04-10 1998-04-10 Antimitotiske halogenderivater af vinka-alkaloider

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK98920607T DK0975640T3 (da) 1997-04-10 1998-04-10 Antimitotiske halogenderivater af vinka-alkaloider

Country Status (15)

Country Link
US (1) US6127377A (da)
EP (3) EP0975640B1 (da)
JP (3) JP4401440B2 (da)
AT (2) ATE270297T1 (da)
AU (1) AU737549C (da)
BR (2) BR9807944B1 (da)
CA (3) CA2286560C (da)
CY (2) CY1111476T1 (da)
DE (3) DE122010000054I1 (da)
DK (2) DK1764368T3 (da)
ES (2) ES2222588T3 (da)
FR (2) FR2761990B1 (da)
LU (1) LU91769I2 (da)
PT (2) PT1764368E (da)
WO (1) WO1998045301A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2761990B1 (fr) * 1997-04-10 1999-06-25 Pf Medicament Derives halogenes antimitotiques d'alcaloides de vinca
US6890558B2 (en) * 2002-05-31 2005-05-10 R.P. Scherer Technologies, Inc. Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
US7238704B2 (en) * 2003-12-04 2007-07-03 Amr Technology, Inc. Vinca derivatives
WO2005055943A2 (en) * 2003-12-04 2005-06-23 Amr Technology, Inc. Vinorelbine derivatives
US20110015221A1 (en) * 2003-12-23 2011-01-20 Pierre Fabre Medicament Pharmaceutical composition of vinflunine which is intended for parenteral administration preparation method thereof and use of same
FR2863891B1 (fr) * 2003-12-23 2006-03-24 Pf Medicament Composition pharmaceutique de vinflunine destinee a une administration parentale, procede de preparation et utilisation
US7772177B2 (en) 2005-05-18 2010-08-10 Aegera Therapeutics, Inc. BIR domain binding compounds
FR2894966B1 (fr) 2005-12-20 2008-03-14 Pierre Fabre Medicament Sa Nouvelle forme cristalline de la vinflunine
EP2024362A4 (en) 2006-05-16 2012-01-25 Pharmascience Inc IAP BIR DOMAIN BINDING COMPOUNDS
US20080125451A1 (en) * 2006-09-12 2008-05-29 Amr Technology, Inc. Vinorelbine derivatives
US8039453B2 (en) * 2006-09-12 2011-10-18 Albany Molecular Research, Inc. Vinca derivatives
FR2905949B1 (fr) * 2006-09-20 2008-11-21 Pierre Fabre Medicament Sa Derives fluores de catharanthine, leur preparation et leur utilisation comme precurseurs d'alcaloides dimeres de vinca
FR2910812B1 (fr) * 2006-12-29 2009-03-20 Pierre Fabre Medicament Sa Compositions pharmaceutiques injectables lyophilisees de derives hemi-synthetiques d'alcaloide de vinca stables a temperature ambiante
FR2912406B1 (fr) * 2007-02-13 2009-05-08 Pierre Fabre Medicament Sa Sels cristalins anhydres de vinflunine, procede de preparation et utilisation en tant que medicament et moyen de purification de la vinflunine.
FR2918567B1 (fr) * 2007-07-11 2012-08-03 Pf Medicament Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
FR2918566B1 (fr) * 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
US20090076055A1 (en) * 2007-09-14 2009-03-19 Protia, Llc Deuterium-enriched vinflunine
DE102010020994B4 (de) * 2010-01-27 2022-01-27 Interpane Entwicklungs-Und Beratungsgesellschaft Mbh Verfahren zur Herstellung eines beschichteten Gegenstands mit Texturätzen
PH12012501813A1 (en) 2010-02-12 2012-12-10 Pharmascience Inc Iap bir domain binding compounds
AU2011218391B2 (en) * 2010-02-22 2015-01-22 The Scripps Research Institute 10'-fluorinated vinca alkaloids provide enhanced biological activity against MDR cancer cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707988B1 (fr) * 1993-07-21 1995-10-13 Pf Medicament Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.
FR2761990B1 (fr) * 1997-04-10 1999-06-25 Pf Medicament Derives halogenes antimitotiques d'alcaloides de vinca

Also Published As

Publication number Publication date
EP1357125A3 (fr) 2003-11-26
FR10C0045I1 (da) 2010-10-29
JP4307292B2 (ja) 2009-08-05
EP1357125A2 (fr) 2003-10-29
DK0975640T3 (da) 2004-11-01
CA2286560A1 (fr) 1998-10-15
FR2761990A1 (fr) 1998-10-16
CA2665949C (fr) 2013-06-11
JP2001518892A (ja) 2001-10-16
BR9816177B1 (pt) 2010-08-24
CA2455416A1 (fr) 1998-10-15
DE69824840T2 (de) 2005-07-21
EP1764368A1 (fr) 2007-03-21
CA2286560C (fr) 2009-09-08
ES2347878T3 (es) 2010-11-22
PT1764368E (pt) 2010-09-16
CY2010019I1 (el) 2012-01-25
EP0975640A1 (fr) 2000-02-02
EP1764368B1 (fr) 2010-07-14
EP0975640B1 (fr) 2004-06-30
CY2010019I2 (el) 2012-01-25
CA2455416C (fr) 2010-11-02
FR10C0045I2 (fr) 2011-04-29
DE122010000054I1 (de) 2011-05-05
AU737549C (en) 2002-03-28
ATE270297T1 (de) 2004-07-15
BR9807944A (pt) 2000-03-08
WO1998045301A1 (fr) 1998-10-15
PT975640E (pt) 2004-11-30
LU91769I2 (fr) 2011-02-22
DE69841766D1 (de) 2010-08-26
JP4401440B2 (ja) 2010-01-20
US6127377A (en) 2000-10-03
CA2665949A1 (fr) 1998-10-15
CY1111476T1 (el) 2012-01-25
ATE473987T1 (de) 2010-07-15
FR2761990B1 (fr) 1999-06-25
AU737549B2 (en) 2001-08-23
JP2004277418A (ja) 2004-10-07
BR9807944B1 (pt) 2011-02-08
JP2009167196A (ja) 2009-07-30
DE69824840D1 (de) 2004-08-05
ES2222588T3 (es) 2005-02-01
AU7340898A (en) 1998-10-30

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