DK1756064T3 - Pyrazolderivater, sammensætninger indeholdende sådanne forbindelser og anvendelsesmetoder - Google Patents
Pyrazolderivater, sammensætninger indeholdende sådanne forbindelser og anvendelsesmetoderInfo
- Publication number
- DK1756064T3 DK1756064T3 DK05754758T DK05754758T DK1756064T3 DK 1756064 T3 DK1756064 T3 DK 1756064T3 DK 05754758 T DK05754758 T DK 05754758T DK 05754758 T DK05754758 T DK 05754758T DK 1756064 T3 DK1756064 T3 DK 1756064T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- methods
- compositions containing
- pyrazole derivatives
- pyrazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57711604P | 2004-06-04 | 2004-06-04 | |
PCT/US2005/018828 WO2005121097A2 (en) | 2004-06-04 | 2005-05-31 | Pyrazole derivatives, compositions containing such compounds and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1756064T3 true DK1756064T3 (da) | 2008-09-22 |
Family
ID=35335786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK05754758T DK1756064T3 (da) | 2004-06-04 | 2005-05-31 | Pyrazolderivater, sammensætninger indeholdende sådanne forbindelser og anvendelsesmetoder |
Country Status (34)
Country | Link |
---|---|
US (2) | US7598285B2 (da) |
EP (1) | EP1756064B1 (da) |
JP (2) | JP4108739B2 (da) |
CN (1) | CN1964947A (da) |
AR (2) | AR049291A1 (da) |
AT (1) | ATE395338T1 (da) |
AU (2) | AU2005252183B2 (da) |
BR (1) | BRPI0511703B8 (da) |
CA (1) | CA2566945C (da) |
CR (1) | CR8766A (da) |
CY (1) | CY1108544T1 (da) |
DE (1) | DE602005006806D1 (da) |
DK (1) | DK1756064T3 (da) |
EA (1) | EA012431B1 (da) |
EC (1) | ECSP067062A (da) |
ES (1) | ES2306165T3 (da) |
GE (1) | GEP20094605B (da) |
HR (1) | HRP20080311T3 (da) |
IL (1) | IL179754A (da) |
MA (1) | MA28673B1 (da) |
MX (1) | MXPA06014084A (da) |
MY (1) | MY143599A (da) |
NI (1) | NI200600290A (da) |
NO (1) | NO339149B1 (da) |
NZ (1) | NZ551405A (da) |
PE (1) | PE20060427A1 (da) |
PL (1) | PL1756064T3 (da) |
PT (1) | PT1756064E (da) |
SI (1) | SI1756064T1 (da) |
TN (1) | TNSN06397A1 (da) |
TW (1) | TWI293952B (da) |
UA (1) | UA85884C2 (da) |
WO (1) | WO2005121097A2 (da) |
ZA (1) | ZA200609489B (da) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2004210127B2 (en) | 2003-01-27 | 2009-10-01 | Merck Sharp & Dohme Corp. | Substituted pyrazoles, compositions containing such compounds and methods of use |
UA85884C2 (uk) | 2004-06-04 | 2009-03-10 | Мерк Енд Ко., Інк. | Похідні піразолу, композиція, що містить ці сполуки, і спосіб застосування (варіанти) |
CA2574147A1 (en) * | 2004-07-22 | 2006-02-09 | Linda Brockunier | Substituted pyrazoles, compositions containing such compounds and methods of use |
AU2006276072A1 (en) | 2005-07-26 | 2007-02-08 | Merck Sharp & Dohme Corp. | Process for synthesizing a substituted pyrazole |
AR056574A1 (es) * | 2005-10-19 | 2007-10-10 | Merck & Co Inc | Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de uso |
EP2114891A1 (en) * | 2007-01-17 | 2009-11-11 | Laboratorios Del. Dr. Esteve, S.A. | Substituted pyrazoline compounds with acat inhibition activity |
DK2129654T3 (da) | 2007-02-09 | 2014-08-25 | Metabasis Therapeutics Inc | Antagonister af glucagonreceptoren |
EP2170337A4 (en) * | 2007-06-28 | 2013-12-18 | Abbvie Inc | NEW TRIAZOLOPYRIDAZINE |
US8232413B2 (en) * | 2007-09-12 | 2012-07-31 | Merck Sharp & Dohme Corp. | Process for the production of a crystalline glucagon receptor antagonist compound |
JP5465658B2 (ja) | 2008-03-05 | 2014-04-09 | 武田薬品工業株式会社 | 複素環化合物 |
US8722094B2 (en) | 2008-03-11 | 2014-05-13 | Aska Pharmaceutical Co., Ltd. | Solid dispersion and pharmaceutical composition of the same, and production processes thereof |
EP2291358B1 (en) | 2008-05-16 | 2018-03-28 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonists, compositions, and methods for their use |
DK2799428T3 (da) | 2008-08-13 | 2017-02-20 | Metabasis Therapeutics Inc | Glucagon-antagonister |
RU2008135294A (ru) * | 2008-08-29 | 2010-03-10 | Дик Корпорейшн (Jp) | Нафталиновые производные |
WO2010030722A1 (en) * | 2008-09-15 | 2010-03-18 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
CA2738663A1 (en) * | 2008-10-03 | 2010-04-08 | Schering Corporation | Spiro-imidazolone derivatives as glucagon receptor antagonists |
US8324384B2 (en) | 2009-02-12 | 2012-12-04 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
WO2010098994A1 (en) | 2009-02-25 | 2010-09-02 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
WO2010144664A1 (en) * | 2009-06-12 | 2010-12-16 | Schering Corporation | Thiophenes as glucagon receptor antagonists, compositions, and methods for their use |
EP2480077B1 (en) | 2009-09-22 | 2015-02-18 | Merck Sharp & Dohme Corp. | Pyrrolidines as glucagon receptor antagonists, compositions, and methods for their use |
MX2013006768A (es) | 2010-12-23 | 2013-07-22 | Pfizer | Moduladores de receptor de glucagon. |
ES2597972T3 (es) | 2011-02-08 | 2017-01-24 | Pfizer Inc | Modulador del receptor de glucagón |
WO2013014569A1 (en) | 2011-07-22 | 2013-01-31 | Pfizer Inc. | Quinolinyl glucagon receptor modulators |
TW201427658A (zh) | 2012-12-10 | 2014-07-16 | Merck Sharp & Dohme | 藉由投予升糖素受體拮抗劑及膽固醇吸收抑制劑治療糖尿病之方法 |
US9649294B2 (en) | 2013-11-04 | 2017-05-16 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
CN103933032B (zh) * | 2013-12-30 | 2019-08-23 | 北京赛林泰医药技术有限公司 | 作为抗癌药物的吡唑类衍生物的使用方法和用途 |
JP2017519000A (ja) | 2014-06-12 | 2017-07-13 | リガンド・ファーマシューティカルズ・インコーポレイテッド | グルカゴンアンタゴニスト |
US10995146B2 (en) | 2016-08-30 | 2021-05-04 | Regeneron Pharmaceuticals, Inc. | Methods of treating severe insulin resistance by interfering with glucagon receptor signaling |
TWI763705B (zh) * | 2016-09-06 | 2022-05-11 | 比利時商健生藥品公司 | 可作為升糖素受體拮抗劑之吲哚衍生物 |
US20190248888A1 (en) | 2016-10-20 | 2019-08-15 | Regeneron Pharmaceuticals, Inc. | Methods of lowering blood glucose levels |
CA3071387A1 (en) | 2017-08-22 | 2019-02-28 | Regeneron Pharmaceuticals, Inc. | Methods of treating urea cycle disorders by interfering with glucagon receptor signaling |
CN111954560A (zh) | 2018-02-13 | 2020-11-17 | 配体药物公司 | 胰高血糖素受体拮抗剂 |
Family Cites Families (35)
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GB9303993D0 (en) | 1993-02-26 | 1993-04-14 | Fujisawa Pharmaceutical Co | New heterocyclic derivatives |
JPH11514651A (ja) | 1995-10-31 | 1999-12-14 | メルク エンド カンパニー インコーポレーテッド | 置換ピリジルピロール、前記化合物を含む組成物及び使用方法 |
AR008789A1 (es) | 1996-07-31 | 2000-02-23 | Bayer Corp | Piridinas y bifenilos substituidos |
US5776954A (en) | 1996-10-30 | 1998-07-07 | Merck & Co., Inc. | Substituted pyridyl pyrroles, compositions containing such compounds and methods of use |
EP0959885A4 (en) | 1996-11-20 | 2002-07-17 | Merck & Co Inc | TRIARYL SUBSTITUTED IMIDAZOLES AND METHODS OF USE |
JP2000514088A (ja) | 1996-11-20 | 2000-10-24 | メルク エンド カンパニー インコーポレーテッド | グルカゴンアンタゴニストとしてのトリアリール置換イミダゾール |
CA2271963A1 (en) | 1996-11-20 | 1998-05-28 | Linda L. Chang | Triaryl substituted imidazoles, compositions containing such compounds and methods of use |
DE69719544T2 (de) | 1996-12-12 | 2003-11-06 | Banyu Pharmaceutical Co., Ltd. | Pyrazolderivate |
EP0979077A1 (en) | 1997-04-18 | 2000-02-16 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders |
US6613942B1 (en) | 1997-07-01 | 2003-09-02 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
CN1282319A (zh) | 1997-10-09 | 2001-01-31 | 小野药品工业株式会社 | 氨基丁酸衍生物 |
IL136711A0 (en) | 1997-12-19 | 2001-06-14 | Amgen Inc | Substituted pyridine and pyridazine compounds and their pharmaceutical use |
DE69939481D1 (de) | 1998-09-17 | 2008-10-16 | Bristol Myers Squibb Co | Methode zur behandlung von diabetes die einen ap2-inhibitor und dazugehörige kombinationen verwendet |
US6503949B1 (en) | 1999-05-17 | 2003-01-07 | Noro Nordisk A/S | Glucagon antagonists/inverse agonists |
CN1229358C (zh) | 1999-08-10 | 2005-11-30 | 日本拜耳农药株式会社 | 新的四唑啉酮衍生物 |
ATE271049T1 (de) * | 1999-11-10 | 2004-07-15 | Takeda Chemical Industries Ltd | Fünfgliedrige n-heterocyclen mit hypoglykämischer und hypolipidemischer wirkung |
US6562807B2 (en) | 2000-06-23 | 2003-05-13 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
WO2002008188A1 (en) * | 2000-07-25 | 2002-01-31 | Merck & Co., Inc. | N-substituted indoles useful in the treatment of diabetes |
WO2002040444A1 (en) | 2000-11-17 | 2002-05-23 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
US20030203946A1 (en) | 2000-11-17 | 2003-10-30 | Carsten Behrens | Glucagon antagonists/inverse agonists |
ITMI20010733A1 (it) | 2001-04-05 | 2002-10-05 | Recordati Chem Pharm | Uso di inibitori dell'isoenzina cox-2 per il trattamento dell'incontinenza urinaria |
US6881746B2 (en) | 2001-12-03 | 2005-04-19 | Novo Nordick A/S | Glucagon antagonists/inverse agonists |
US6762318B2 (en) | 2001-12-03 | 2004-07-13 | Novo Nordisk A/S | Glucagon antagonists |
AU2002351730A1 (en) | 2001-12-19 | 2003-06-30 | Novo Nordisk A/S | Glucagon receptor antagonists/inverse agonists |
AU2002347022A1 (en) | 2001-12-20 | 2003-07-09 | Novo Nordisk A/S | Benzimidazols and indols as glucagon receptor antagonists/inverse agonisten |
BR0307409A (pt) | 2002-02-01 | 2004-12-28 | Dainippon Pharmaceutical Co | Compostos de hidrazida de ácido 2-furanocarboxìlico, composições farmacêuticas contendo os mesmos e uso dos mesmos para preparação de um agente preventivo ou terapêutico |
WO2004009158A2 (en) | 2002-07-19 | 2004-01-29 | Baxter International Inc. | Systems and methods for performing peritoneal dialysis |
EP1400243A1 (en) | 2002-09-19 | 2004-03-24 | Tanabe Seiyaku Co., Ltd. | Calcium-activated K channel activator |
JP2006509015A (ja) * | 2002-12-04 | 2006-03-16 | メルク エンド カムパニー インコーポレーテッド | スピロ環尿素、そのような化合物を含有する組成物、及び使用方法 |
AU2004210127B2 (en) | 2003-01-27 | 2009-10-01 | Merck Sharp & Dohme Corp. | Substituted pyrazoles, compositions containing such compounds and methods of use |
EP1633354B1 (en) * | 2003-04-14 | 2008-01-23 | The Institutes for Pharmaceutical Discovery, LLC | N-(((((1,3-thiazol-2-yl)amino)carbonyl)phenyl)sulfonyl)phenylalanine derivatives and related compounds for the treatment of diabetes |
WO2004100875A2 (en) * | 2003-05-09 | 2004-11-25 | Merck & Co., Inc. | Benzimidazoles, compositions containing such compounds and methods of use |
UA85884C2 (uk) * | 2004-06-04 | 2009-03-10 | Мерк Енд Ко., Інк. | Похідні піразолу, композиція, що містить ці сполуки, і спосіб застосування (варіанти) |
CA2574147A1 (en) * | 2004-07-22 | 2006-02-09 | Linda Brockunier | Substituted pyrazoles, compositions containing such compounds and methods of use |
AR056574A1 (es) * | 2005-10-19 | 2007-10-10 | Merck & Co Inc | Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de uso |
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2005
- 2005-05-31 UA UAA200700111A patent/UA85884C2/uk unknown
- 2005-05-31 MX MXPA06014084A patent/MXPA06014084A/es active IP Right Grant
- 2005-05-31 PL PL05754758T patent/PL1756064T3/pl unknown
- 2005-05-31 DE DE602005006806T patent/DE602005006806D1/de active Active
- 2005-05-31 EA EA200602196A patent/EA012431B1/ru not_active IP Right Cessation
- 2005-05-31 PT PT05754758T patent/PT1756064E/pt unknown
- 2005-05-31 ES ES05754758T patent/ES2306165T3/es active Active
- 2005-05-31 WO PCT/US2005/018828 patent/WO2005121097A2/en active IP Right Grant
- 2005-05-31 GE GEAP20059788A patent/GEP20094605B/en unknown
- 2005-05-31 DK DK05754758T patent/DK1756064T3/da active
- 2005-05-31 JP JP2007515416A patent/JP4108739B2/ja not_active Expired - Fee Related
- 2005-05-31 BR BRPI0511703A patent/BRPI0511703B8/pt not_active IP Right Cessation
- 2005-05-31 SI SI200530296T patent/SI1756064T1/sl unknown
- 2005-05-31 NZ NZ551405A patent/NZ551405A/en not_active IP Right Cessation
- 2005-05-31 MY MYPI20052470A patent/MY143599A/en unknown
- 2005-05-31 CN CNA2005800182634A patent/CN1964947A/zh active Pending
- 2005-05-31 AU AU2005252183A patent/AU2005252183B2/en not_active Ceased
- 2005-05-31 CA CA2566945A patent/CA2566945C/en not_active Expired - Fee Related
- 2005-05-31 EP EP05754758A patent/EP1756064B1/en active Active
- 2005-05-31 AT AT05754758T patent/ATE395338T1/de active
- 2005-06-02 PE PE2005000624A patent/PE20060427A1/es not_active Application Discontinuation
- 2005-06-02 AR ARP050102266A patent/AR049291A1/es active IP Right Grant
- 2005-06-03 TW TW094118496A patent/TWI293952B/zh not_active IP Right Cessation
- 2005-06-03 US US11/144,332 patent/US7598285B2/en active Active
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2006
- 2006-11-15 ZA ZA200609489A patent/ZA200609489B/en unknown
- 2006-11-23 CR CR8766A patent/CR8766A/es unknown
- 2006-11-30 NI NI200600290A patent/NI200600290A/es unknown
- 2006-11-30 IL IL179754A patent/IL179754A/en active IP Right Grant
- 2006-12-01 TN TNP2006000397A patent/TNSN06397A1/en unknown
- 2006-12-04 EC EC2006007062A patent/ECSP067062A/es unknown
- 2006-12-20 MA MA29545A patent/MA28673B1/fr unknown
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2007
- 2007-01-04 NO NO20070073A patent/NO339149B1/no not_active IP Right Cessation
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2008
- 2008-02-05 JP JP2008025035A patent/JP4733153B2/ja not_active Expired - Fee Related
- 2008-07-01 HR HR20080311T patent/HRP20080311T3/xx unknown
- 2008-07-21 CY CY20081100762T patent/CY1108544T1/el unknown
- 2008-09-30 AU AU2008229701A patent/AU2008229701C1/en not_active Ceased
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2009
- 2009-03-17 US US12/405,600 patent/US7799818B2/en active Active
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2012
- 2012-11-20 AR ARP120104354A patent/AR088919A2/es unknown
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