DK1670769T3 - Benzimidazol-derivater, sammensætninger indeholdende disse, fremstilling deraf og anvendelser deraf - Google Patents

Benzimidazol-derivater, sammensætninger indeholdende disse, fremstilling deraf og anvendelser deraf

Info

Publication number: DK1670769T3
Authority: DK; Denmark
Prior art keywords: preparation; compositions containing; benzimidazole derivatives; benzimidazole; derivatives
Prior art date: 2003-09-26

Application number

DK04768667T

Other languages

English (en)

Inventor

Ziping Liu

Christopher Walpole

Hua Yang

Daniel Page

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-26

Filing date

2004-09-24

Publication date

2009-08-10

2004-09-24 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2009-08-10 Application granted granted Critical

2009-08-10 Publication of DK1670769T3 publication Critical patent/DK1670769T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK04768667T 2003-09-26 2004-09-24 Benzimidazol-derivater, sammensætninger indeholdende disse, fremstilling deraf og anvendelser deraf DK1670769T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0302573A SE0302573D0 (sv)	2003-09-26	2003-09-26	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
PCT/GB2004/004124 WO2005030732A1 (en)	2003-09-26	2004-09-24	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Publications (1)

Publication Number	Publication Date
DK1670769T3 true DK1670769T3 (da)	2009-08-10

Family

ID=29246982

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04768667T DK1670769T3 (da)	2003-09-26	2004-09-24	Benzimidazol-derivater, sammensætninger indeholdende disse, fremstilling deraf og anvendelser deraf

Country Status (34)

Country	Link
US (1)	US8633235B2 (da)
EP (1)	EP1670769B1 (da)
JP (1)	JP4896721B2 (da)
KR (1)	KR101170184B1 (da)
CN (2)	CN102010373A (da)
AR (1)	AR045819A1 (da)
AT (1)	ATE430135T1 (da)
AU (1)	AU2004276062B2 (da)
BR (1)	BRPI0414780B8 (da)
CA (1)	CA2539738C (da)
CO (1)	CO5680443A2 (da)
CY (1)	CY1110332T1 (da)
DE (1)	DE602004020907D1 (da)
DK (1)	DK1670769T3 (da)
ES (1)	ES2324669T3 (da)
HK (1)	HK1089436A1 (da)
HR (1)	HRP20090388T1 (da)
IL (1)	IL174215A0 (da)
IS (1)	IS8422A (da)
MX (1)	MXPA06003197A (da)
MY (1)	MY140630A (da)
NO (1)	NO20061839L (da)
NZ (1)	NZ545736A (da)
PL (1)	PL1670769T3 (da)
PT (1)	PT1670769E (da)
RU (1)	RU2346938C2 (da)
SA (1)	SA04250310B1 (da)
SE (1)	SE0302573D0 (da)
SI (1)	SI1670769T1 (da)
TW (1)	TW200521117A (da)
UA (1)	UA86776C2 (da)
UY (1)	UY28536A1 (da)
WO (1)	WO2005030732A1 (da)
ZA (3)	ZA200602446B (da)

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AU2005287427B2 (en) *	2004-09-24	2009-03-26	Astrazeneca Ab	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof I
CA2582507A1 (en) *	2004-09-24	2006-03-30	Astrazeneca Ab	Compounds, compositions containing them, preparation thereof and uses thereof iii
ES2380709T3 (es)	2004-09-24	2012-05-17	Astrazeneca Ab	Derivados de bencimidazol, composiciones que los contienen, su preparación y usos
CN101052639B (zh) *	2004-09-24	2010-10-27	阿斯利康(瑞典)有限公司	苯并咪唑衍生物、含有它们的组合物、其制备方法和其用途
MX2007005290A (es)	2004-11-02	2007-07-09	Pfizer	Derivados de sulfonilbencimidazol.
JP2009502912A (ja) *	2005-07-29	2009-01-29	アストラゼネカ・アクチエボラーグ	ジェミナル（（ジフルオロシクロアルキル）メチル）アミンの製造方法
TW200745049A (en)	2006-03-23	2007-12-16	Astrazeneca Ab	New crystalline forms
TW200808769A (en) *	2006-04-18	2008-02-16	Astrazeneca Ab	Therapeutic compounds
US20080139846A1 (en) *	2006-09-01	2008-06-12	Astrazeneca Ab	New Process 298
EP2070927A4 (en) *	2006-09-13	2010-10-13	Kyowa Hakko Kirin Co Ltd	CONDENSED HETEROCYCLIC DERIVATIVE
US20110086853A1 (en) *	2009-10-08	2011-04-14	William Brown	Therapeutic Compounds
RU2454234C1 (ru) *	2011-03-16	2012-06-27	Константин Михайлович Аверин	Соли 1,3-диэтилбензимидазолия - иммуностимулирующие средства и фармацевтические композиции на их основе
AU2013274385B2 (en) *	2012-06-13	2017-11-30	Cytec Technology Corp.	Stabilizer compositions containing substituted chroman compounds and methods of use
MX2014016054A (es)	2012-06-26	2015-04-10	Bayer Pharma AG	N-[4-(quinolin-4-iloxi)ciclohexil(metil)](hetero)arilcarboxamidas como antagonistas del receptor de androgenos, su produccion y usos como productos medicinales.
EP3762379A1 (en)	2018-03-07	2021-01-13	Bayer Aktiengesellschaft	Identification and use of erk5 inhibitors
WO2020234103A1 (en)	2019-05-21	2020-11-26	Bayer Aktiengesellschaft	Identification and use of kras inhibitors
CN112010789A (zh) *	2019-05-31	2020-12-01	中国科学院上海药物研究所	乙烯基磺酰胺或乙烯基酰胺类化合物及其制备方法和用途
CN119013276A (zh) *	2022-03-04	2024-11-22	三进制药株式会社	新型杂环化合物和包含该化合物的药物组合物

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2003
- 2003-09-26 SE SE0302573A patent/SE0302573D0/xx unknown
2004
- 2004-09-24 BR BRPI0414780A patent/BRPI0414780B8/pt active IP Right Grant
- 2004-09-24 MX MXPA06003197A patent/MXPA06003197A/es active IP Right Grant
- 2004-09-24 TW TW093129150A patent/TW200521117A/zh unknown
- 2004-09-24 CN CN2010105277900A patent/CN102010373A/zh active Pending
- 2004-09-24 PT PT04768667T patent/PT1670769E/pt unknown
- 2004-09-24 NZ NZ545736A patent/NZ545736A/en unknown
- 2004-09-24 DE DE602004020907T patent/DE602004020907D1/de not_active Expired - Lifetime
- 2004-09-24 KR KR1020067005825A patent/KR101170184B1/ko not_active Expired - Lifetime
- 2004-09-24 DK DK04768667T patent/DK1670769T3/da active
- 2004-09-24 US US10/573,054 patent/US8633235B2/en active Active
- 2004-09-24 AU AU2004276062A patent/AU2004276062B2/en not_active Expired
- 2004-09-24 CA CA2539738A patent/CA2539738C/en not_active Expired - Lifetime
- 2004-09-24 JP JP2006527490A patent/JP4896721B2/ja not_active Expired - Lifetime
- 2004-09-24 UA UAA200602693A patent/UA86776C2/ru unknown
- 2004-09-24 ES ES04768667T patent/ES2324669T3/es not_active Expired - Lifetime
- 2004-09-24 PL PL04768667T patent/PL1670769T3/pl unknown
- 2004-09-24 MY MYPI20043910A patent/MY140630A/en unknown
- 2004-09-24 CN CNA2004800350086A patent/CN1886379A/zh active Pending
- 2004-09-24 RU RU2006113371/04A patent/RU2346938C2/ru active
- 2004-09-24 EP EP04768667A patent/EP1670769B1/en not_active Expired - Lifetime
- 2004-09-24 UY UY28536A patent/UY28536A1/es unknown
- 2004-09-24 AR ARP040103467A patent/AR045819A1/es not_active Application Discontinuation
- 2004-09-24 WO PCT/GB2004/004124 patent/WO2005030732A1/en active Application Filing
- 2004-09-24 SI SI200431166T patent/SI1670769T1/sl unknown
- 2004-09-24 AT AT04768667T patent/ATE430135T1/de active
- 2004-09-26 SA SA04250310A patent/SA04250310B1/ar unknown
2006
- 2006-03-09 IL IL174215A patent/IL174215A0/en unknown
- 2006-03-22 CO CO06028452A patent/CO5680443A2/es not_active Application Discontinuation
- 2006-03-24 ZA ZA200602446A patent/ZA200602446B/en unknown
- 2006-04-21 IS IS8422A patent/IS8422A/is unknown
- 2006-04-26 NO NO20061839A patent/NO20061839L/no not_active Application Discontinuation
- 2006-09-01 HK HK06109758.7A patent/HK1089436A1/xx not_active IP Right Cessation
2007
- 2007-03-13 ZA ZA200702131A patent/ZA200702131B/xx unknown
- 2007-03-16 ZA ZA200702226A patent/ZA200702226B/xx unknown
2009
- 2009-07-07 HR HR20090388T patent/HRP20090388T1/xx unknown
- 2009-07-08 CY CY20091100725T patent/CY1110332T1/el unknown

Also Published As

Publication number	Publication date
TW200521117A (en)	2005-07-01
UY28536A1 (es)	2005-04-29
US8633235B2 (en)	2014-01-21
RU2006113371A (ru)	2007-11-10
EP1670769B1 (en)	2009-04-29
ZA200602446B (en)	2007-09-26
CN102010373A (zh)	2011-04-13
NZ545736A (en)	2009-11-27
SI1670769T1 (sl)	2009-10-31
CA2539738C (en)	2011-11-22
KR20070001052A (ko)	2007-01-03
NO20061839L (no)	2006-06-26
AR045819A1 (es)	2005-11-16
ZA200702131B (en)	2008-08-27
IS8422A (is)	2006-04-21
ZA200702226B (en)	2009-01-28
JP4896721B2 (ja)	2012-03-14
EP1670769A1 (en)	2006-06-21
CO5680443A2 (es)	2006-09-29
KR101170184B1 (ko)	2012-07-31
AU2004276062B2 (en)	2008-05-22
US20080207612A1 (en)	2008-08-28
BRPI0414780B8 (pt)	2021-05-25
CA2539738A1 (en)	2005-04-07
IL174215A0 (en)	2006-08-01
CY1110332T1 (el)	2015-01-14
BRPI0414780A (pt)	2006-11-21
JP2007506721A (ja)	2007-03-22
BRPI0414780B1 (pt)	2018-10-23
PT1670769E (pt)	2009-07-09
HK1089436A1 (en)	2006-12-01
PL1670769T3 (pl)	2009-09-30
WO2005030732A1 (en)	2005-04-07
MXPA06003197A (es)	2006-06-23
RU2346938C2 (ru)	2009-02-20
SA04250310B1 (ar)	2009-01-19
DE602004020907D1 (de)	2009-06-10
ATE430135T1 (de)	2009-05-15
CN1886379A (zh)	2006-12-27
HRP20090388T1 (en)	2009-08-31
AU2004276062A1 (en)	2005-04-07
ES2324669T3 (es)	2009-08-12
UA86776C2 (ru)	2009-05-25
SE0302573D0 (sv)	2003-09-26
MY140630A (en)	2010-01-15

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