DK1753720T3 - Fremgangsmåde til fremstilling af perindopril og salte deraf - Google Patents

Fremgangsmåde til fremstilling af perindopril og salte deraf

Info

Publication number: DK1753720T3
Authority: DK; Denmark
Prior art keywords: perindopril; salts; preparation
Prior art date: 2004-05-14

Application number

DK05748048.5T

Other languages

English (en)

Inventor

Marjo Merslavic

Janja Smid

Zdenka Tomsic

Original Assignee

Servier S A Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-05-14

Filing date

2005-05-10

Publication date

2014-06-30

2005-05-10 Application filed by Servier S A Lab filed Critical Servier S A Lab

2014-06-30 Application granted granted Critical

2014-06-30 Publication of DK1753720T3 publication Critical patent/DK1753720T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Indole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK05748048.5T 2004-05-14 2005-05-10 Fremgangsmåde til fremstilling af perindopril og salte deraf DK1753720T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
SI200400143A SI21800A (sl)	2004-05-14	2004-05-14	Nov postopek sinteze perindoprila
SI200400235A SI21852A (sl)	2004-05-14	2004-08-05	Nov postopek sinteze perindoprila
PCT/EP2005/005048 WO2005113500A1 (en)	2004-05-14	2005-05-10	Process for the preparation of perindopril and salts thereof

Publications (1)

Publication Number	Publication Date
DK1753720T3 true DK1753720T3 (da)	2014-06-30

Family

ID=34969318

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05748048.5T DK1753720T3 (da)	2004-05-14	2005-05-10	Fremgangsmåde til fremstilling af perindopril og salte deraf

Country Status (17)

Country	Link
US (1)	US7674814B2 (da)
EP (1)	EP1753720B1 (da)
JP (1)	JP5032983B2 (da)
AU (1)	AU2005245087B2 (da)
CA (1)	CA2566754C (da)
CY (1)	CY1115222T1 (da)
DK (1)	DK1753720T3 (da)
EA (1)	EA011322B1 (da)
ES (1)	ES2466248T3 (da)
HR (1)	HRP20140487T1 (da)
NO (1)	NO337892B1 (da)
PL (1)	PL1753720T3 (da)
PT (1)	PT1753720E (da)
SI (3)	SI21800A (da)
UA (1)	UA83139C2 (da)
WO (1)	WO2005113500A1 (da)
ZA (1)	ZA200609915B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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JP4948392B2 (ja) *	2004-03-29	2012-06-06	レラボラトアセルビエ	固形薬学的組成物を調製するためのプロセス
US7291745B2 (en)	2005-03-21	2007-11-06	Glenmark Pharmaceuticals Limited	Process for the preparation of perindopril
JP2006290825A (ja) *	2005-04-13	2006-10-26	Shiono Chemical Co Ltd	アルファ型ペリンドプリルエルブミンの製造法
SI22543A (sl)	2007-06-27	2008-12-31	Krka, Tovarna Zdravil, D.D., Novo Mesto	Nove soli perindoprila
WO2016178591A2 (en)	2015-05-05	2016-11-10	Gene Predit, Sa	Genetic markers and treatment of male obesity
PH12018502155B1 (en)	2016-04-20	2024-03-27	Servier Lab	Pharmaceutical composition comprising a beta blocker, a converting enzyme inhibitor and an antihypertensive or an nsaid
JP7070831B2 (ja)	2018-05-31	2022-05-18	株式会社富士通ゼネラル	天井埋込型空気調和機

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FR2807430B1 (fr)	2000-04-11	2002-05-17	Adir	Nouveau procede de synthese des esters de la n-[(s)-1- carboxybutyl]-(s)-alanine et application a la synthese du perindopril
FR2811318B1 (fr)	2000-07-06	2002-08-23	Adir	Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811319B1 (fr) *	2000-07-06	2002-08-23	Adir	Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811320B1 (fr) *	2000-07-06	2002-08-23	Adir	Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
DE10131217A1 (de) *	2001-06-28	2003-01-09	Solvay Pharm Gmbh	3-Phenyl-3,7-diazabicyclo 3,3,1 nonan-Verbindungen sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
WO2003030872A2 (en) *	2001-10-12	2003-04-17	Elan Pharma International Ltd.	Compositions having a combination of particles for immediate release and for controlled release
ES2283774T3 (es)	2002-01-15	2007-11-01	Actavis Group Hf.	Formulaciones de quinapril e inhibidores de la eca relacionados.
ES2289060T3 (es) *	2002-01-30	2008-02-01	Les Laboratoires Servier	Proceso para la preparacion de perindopril de alta pureza y de intermedios utiles en su sintesis.
AU2003217916A1 (en)	2002-03-08	2003-09-22	Teva Pharmeceuticals Usa, Inc.	Stable formulations of angiotensin converting enzyme (ace) inhibitors
FR2838648B1 (fr)	2002-04-18	2004-05-21	Servier Lab	Nouveau sel de perindopril et les compositions pharmaceutiques qui le contiennent
US7763278B2 (en) *	2002-06-10	2010-07-27	Elan Pharma International Ltd.	Nanoparticulate polycosanol formulations and novel polycosanol combinations
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ES2307923T3 (es) *	2003-02-28	2008-12-01	Les Laboratoires Servier S.A.	Procedimiento de preparacion de perindopril y sales del mismo.
DE60301980T2 (de) *	2003-02-28	2006-07-27	Les Laboratoires Servier	Verfahren zur Synthese des (2S,3aS,7aS)-perhydroindol-2-carbonsäures und seiner Estern, Verwendung in der Synthese von Perindopril
ES2231760T3 (es)	2003-03-12	2005-05-16	Les Laboratoires Servier	Nuevo procedimiento de sintesis del acido(2s, 3as,7as)perhidroindol-2-carboxilico y de sus esteres, y su aplicacion a la sintesis de perindopril.
EP1367061B1 (fr) *	2003-06-30	2006-01-04	Les Laboratoires Servier	Nouveau procédé de synthèse du perindopril et de ses sels pharmaceutiquement acceptables
US6869963B2 (en) *	2003-07-11	2005-03-22	Sandoz Ag	Stable pharmaceutical compositions containing an ACE inhibitor
GB2404336A (en)	2003-07-30	2005-02-02	Cipla Ltd	Stabilisation of therapeutic agents using a carbonate salt of an amino acid, preferably in the presence of a saccharide, & pharmaceutical compositions thereof
ES2271498T3 (es) *	2003-07-31	2007-04-16	Les Laboratoires Servier	Nuevo procedimiento de sintesis de perindopril y de sus sales farmaceuticamente aceptables.
SI1367062T1 (sl) *	2003-07-31	2006-12-31	Servier Lab	Nov postopek sinteze perindoprila in njegovih farmacevtsko sprejemljivih soli
PT1362845E (pt)	2003-09-01	2009-11-05	Servier Lab	Novo processo de síntese dos ésteres da n-((s)-1- carboxibutil)-(s)-alanina e aplicação à síntese do perindopril
DK1400531T3 (da)	2003-09-30	2006-05-15	Servier Lab	Fremgangsmåde til fremstilling af N-[(S)-1-ethoxycarbonyl-butyl]-(S)-alanin og anvendelse heraf ved syntese af perindopril
PT1403278E (pt)	2003-09-30	2005-09-30	Servier Lab	Processo de sintese da n-((s)-1-carbetoxibutil)-(s)-alanina e aplicacao a sintese do perindopril
GB2394660A (en)	2003-12-17	2004-05-05	Niche Generics Ltd	Stabilisation of pharmaceutical compositions comprising ACE inhibitor by absence of acidic excipients having large specific surface area, eg silicon dioxide
JP4948392B2 (ja) *	2004-03-29	2012-06-06	レラボラトアセルビエ	固形薬学的組成物を調製するためのプロセス

2004
- 2004-05-14 SI SI200400143A patent/SI21800A/sl not_active IP Right Cessation
- 2004-08-05 SI SI200400235A patent/SI21852A/sl not_active IP Right Cessation
2005
- 2005-05-10 EA EA200602117A patent/EA011322B1/ru not_active IP Right Cessation
- 2005-05-10 WO PCT/EP2005/005048 patent/WO2005113500A1/en active Application Filing
- 2005-05-10 PT PT57480485T patent/PT1753720E/pt unknown
- 2005-05-10 JP JP2007512069A patent/JP5032983B2/ja not_active Expired - Fee Related
- 2005-05-10 AU AU2005245087A patent/AU2005245087B2/en not_active Ceased
- 2005-05-10 DK DK05748048.5T patent/DK1753720T3/da active
- 2005-05-10 ES ES05748048.5T patent/ES2466248T3/es active Active
- 2005-05-10 PL PL05748048T patent/PL1753720T3/pl unknown
- 2005-05-10 SI SI200531867T patent/SI1753720T1/sl unknown
- 2005-05-10 EP EP05748048.5A patent/EP1753720B1/en active Active
- 2005-05-10 UA UAA200613250A patent/UA83139C2/uk unknown
- 2005-05-10 CA CA2566754A patent/CA2566754C/en not_active Expired - Fee Related
- 2005-05-10 US US11/568,908 patent/US7674814B2/en not_active Expired - Fee Related
2006
- 2006-11-28 ZA ZA200609915A patent/ZA200609915B/en unknown
- 2006-12-11 NO NO20065695A patent/NO337892B1/no not_active IP Right Cessation
2014
- 2014-05-29 HR HRP20140487TT patent/HRP20140487T1/hr unknown
- 2014-07-01 CY CY20141100483T patent/CY1115222T1/el unknown

Also Published As

Publication number	Publication date
EA200602117A1 (ru)	2007-04-27
CA2566754A1 (en)	2005-12-01
SI21852A (sl)	2006-02-28
US20080051584A1 (en)	2008-02-28
PT1753720E (pt)	2014-08-04
NO20065695L (no)	2006-12-11
HRP20140487T1 (hr)	2014-07-04
EA011322B1 (ru)	2009-02-27
NO337892B1 (no)	2016-07-04
SI1753720T1 (sl)	2014-08-29
CY1115222T1 (el)	2017-01-04
UA83139C2 (uk)	2008-06-10
JP2007537189A (ja)	2007-12-20
EP1753720B1 (en)	2014-05-07
US7674814B2 (en)	2010-03-09
ES2466248T3 (es)	2014-06-09
EP1753720A1 (en)	2007-02-21
JP5032983B2 (ja)	2012-09-26
AU2005245087B2 (en)	2010-12-16
ZA200609915B (en)	2008-05-28
CA2566754C (en)	2012-09-18
PL1753720T3 (pl)	2014-09-30
SI21800A (sl)	2005-12-31
WO2005113500A1 (en)	2005-12-01
AU2005245087A1 (en)	2005-12-01

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