DK164917C - Analogifremgangsmaade til fremstilling af bicyklisk substituerede dipeptidderivater og deres farmaceutisk acceptable salte - Google Patents

Analogifremgangsmaade til fremstilling af bicyklisk substituerede dipeptidderivater og deres farmaceutisk acceptable salte

Info

Publication number: DK164917C
Authority: DK; Denmark
Prior art keywords: preparation; acceptable salts; pharmaceutical acceptable; dipeptide derivatives; analogy procedure
Prior art date: 1980-10-31

Application number

DK478181A

Other languages

Danish (da)

English (en)

Other versions

DK478181A (da

DK164917B (da

Inventor

Yoshikazu Oka

Kohei Nishikawa

Akio Miyake

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-10-31

Filing date

1981-10-29

Publication date

1993-02-01

1980-10-31 Priority claimed from JP55154394A external-priority patent/JPS5777651A/ja

1981-04-28 Priority claimed from JP56064371A external-priority patent/JPS57179141A/ja

1981-10-29 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1982-05-01 Publication of DK478181A publication Critical patent/DK478181A/da

1992-09-07 Publication of DK164917B publication Critical patent/DK164917B/da

1993-02-01 Application granted granted Critical

1993-02-01 Publication of DK164917C publication Critical patent/DK164917C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK478181A 1980-10-31 1981-10-29 Analogifremgangsmaade til fremstilling af bicyklisk substituerede dipeptidderivater og deres farmaceutisk acceptable salte DK164917C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP55154394A JPS5777651A (en)	1980-10-31	1980-10-31	Indane derivative and its preparation
JP15439480		1980-10-31
JP56064371A JPS57179141A (en)	1981-04-28	1981-04-28	Bicyclic compound and its preparation
JP6437181		1981-04-28

Publications (3)

Publication Number	Publication Date
DK478181A DK478181A (da)	1982-05-01
DK164917B DK164917B (da)	1992-09-07
DK164917C true DK164917C (da)	1993-02-01

Family

ID=26405485

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK478181A DK164917C (da)	1980-10-31	1981-10-29	Analogifremgangsmaade til fremstilling af bicyklisk substituerede dipeptidderivater og deres farmaceutisk acceptable salte

Country Status (19)

Country	Link
US (3)	US4822818A (es)
EP (1)	EP0051391B1 (es)
KR (1)	KR880000890B1 (es)
AU (1)	AU543804B2 (es)
CA (1)	CA1287444C (es)
DE (1)	DE3165862D1 (es)
DK (1)	DK164917C (es)
ES (3)	ES8306710A1 (es)
FI (1)	FI73698C (es)
GB (1)	GB2086393B (es)
GR (1)	GR75368B (es)
HK (1)	HK19887A (es)
HU (1)	HU183652B (es)
IE (1)	IE51918B1 (es)
MY (1)	MY8500500A (es)
NO (1)	NO155133C (es)
NZ (1)	NZ198826A (es)
PH (2)	PH18357A (es)
PT (1)	PT73912B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4906615A (en) *	1980-12-18	1990-03-06	Schering Corporation	Substituted dipeptides as inhibitors of enkephalinases
US4610816A (en) *	1980-12-18	1986-09-09	Schering Corporation	Substituted dipeptides as inhibitors of enkephalinases
US4596791A (en) *	1983-03-16	1986-06-24	Usv Pharmaceutical Corp.	Compounds for treating hypertension
AT387717B (de) *	1983-03-16	1989-03-10	Immuno Ag	Verfahren zum bestimmen von unvertraeglichkeitsreaktionen verursachenden substanzen in therapeutisch und prophylaktisch anzuwendenden blutprodukten sowie verwendung des verfahrens
US4666906A (en) *	1983-03-16	1987-05-19	Usv Pharmaceutical Corporation	Compounds for treating hypertension
US4564612A (en) *	1983-04-22	1986-01-14	Takeda Chemical Industries, Ltd.	Condensed, seven-membered ring compounds and their use
IL72523A (en) *	1983-08-12	1988-06-30	Takeda Chemical Industries Ltd	3-amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine derivatives,their production and pharmaceutical compositions containing them
US4638000A (en) *	1983-08-12	1987-01-20	Takeda Chemical Industries, Ltd.	Condensed seven-membered ring compounds, their production and use
GB8414987D0 (en) *	1984-06-12	1984-07-18	Beecham Group Plc	Active compounds
EP0187037A3 (en) *	1984-12-21	1988-03-23	Takeda Chemical Industries, Ltd.	Piperidine derivatives, their production and use
DK100788A (da) *	1987-03-04	1988-09-05	Takeda Chemical Industries Ltd	Fremgangsmaade til fremstilling af indanderivater
EP0284510A3 (en) *	1987-03-24	1990-08-22	Asahi Breweries, Ltd.	N-[N alpha-(1(S)-carboxy-3-cyclohexyl-propyl)-1-lysyl] N-cyclopentylglycine as antihypertensives
US4956490A (en) *	1989-03-09	1990-09-11	Merck & Co., Inc.	Process for preparing benzylpyruvic acids and esters
IT1232160B (it) *	1989-07-31	1992-01-25	Sigma Tau Ind Farmaceuti	2-(n-acil)ammino-6,7-dimetossi tetraline, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' antiipertensiva che le contengono
DE4021108A1 (de) *	1990-07-03	1992-01-09	Bayer Ag	Optisch aktive n-(alpha)-fluoracryloyl-aminosaeure-derivate, ihre herstellung, die daraus hergestellten optisch aktiven polymeren und deren verwendung zur spaltung von racematen
DE4123248C2 (de) *	1991-07-13	1996-03-07	Degussa	Verfahren zur Herstellung von N-substituierten alpha-Aminosäuren und alpha-Aminosäure-Derivaten
US5977160A (en) *	1992-04-10	1999-11-02	Brigham And Women's Hospital, Inc.	Methods for reducing risk of repeat myocardial infarction and increasing survival in heart attack victims
TWI243164B (en) *	2001-02-13	2005-11-11	Aventis Pharma Gmbh	Acylated indanyl amines and their use as pharmaceuticals
KR20030046079A (ko) *	2001-12-05	2003-06-12	주식회사 코오롱	고순도 염산 델라프릴의 신규한 정제방법
WO2004098496A2 (en) *	2003-04-30	2004-11-18	Wellstat Therapeutics Corporation	Compounds for the treatment of metabolic disorders
MXPA05012900A (es) *	2003-05-30	2006-02-22	Ranbaxy Lab Ltd	Derivados de pirrol sustituidos.
AU2006313430B2 (en) *	2005-11-08	2012-09-06	Ranbaxy Laboratories Limited	Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
CL2007000667A1 (es) *	2006-03-14	2008-03-14	Ranbaxi Lab Ltd	Composicion farmaceutica que comprende al acido 7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]pirrol-1-il]-3,5-dihidroxi-heptanoico o una sal y al menos un agente estabilizante; procedimiento de preparacion, util en e
ITMI20061364A1 (it) *	2006-07-13	2008-01-14	Dipharma Spa	Procedimento per la preparazione di delapril
CL2007002044A1 (es) *	2006-07-14	2008-06-13	Ranbaxy Lab Ltd	Polimorfo cristalino de la sal hemicalcica del acido (3r,5r)-7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]-pirrol-1-il]-3,5-dihidroxiheptanoico; composicion farmaceutica; y uso para el tratamiento de la diabetes, enf
WO2014202659A1 (en)	2013-06-21	2014-12-24	Sanofi-Aventis Deutschland Gmbh	Process for the preparation of amides of n-[1-(s)-(ethoxycarbonyl)-3-phenylpropyl]-l-alanine
CA3218884A1 (en) *	2021-05-11	2022-11-17	David Nutt	Therapeutic aminoindane compounds and compositions

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4105776A (en) *	1976-06-21	1978-08-08	E. R. Squibb & Sons, Inc.	Proline derivatives and related compounds
US4053651A (en) *	1976-05-10	1977-10-11	E. R. Squibb & Sons, Inc.	Compounds and method for alleviating angiotensin related hypertension
FR2395998A1 (fr) *	1977-06-29	1979-01-26	Yoshitomi Pharmaceutical	Nouveaux derives de la thiazolidine et leur application dans le traitement de l'hypertension
LU78804A1 (de) *	1977-12-30	1979-07-20	Byk Gulden Lomberg Chem Fab	N-substituierte w-aminoalkanoyl-w-aminoalkansaeuren,ihre verwendung und verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US4243678A (en) *	1977-12-30	1981-01-06	Byk Gulden Lomberg Chemische Fabrik Gmbh	Acylhydrocarbylaminoalkanoic acids, compositions and uses
US4316896A (en) *	1978-09-07	1982-02-23	Merck & Co., Inc.	Aminoacid derivatives as antihypertensives
IL58849A (en) *	1978-12-11	1983-03-31	Merck & Co Inc	Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4256761A (en) *	1979-07-13	1981-03-17	Usv Pharmaceutical Corporation	Antihypertensive amides
ZA817261B (en) *	1980-10-23	1982-09-29	Schering Corp	Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
DE3040021A1 (de) *	1980-10-23	1982-05-13	Windmöller & Hölscher, 4540 Lengerich	Vorrichtung zum bilden und stapeln von von einer folienschlauchbahn abgetrennten abschnitten
US4820729A (en) *	1981-03-30	1989-04-11	Rorer Pharmaceutical Corporation	N-substituted-amido-amino acids

1981
- 1981-10-16 AU AU76521/81A patent/AU543804B2/en not_active Ceased
- 1981-10-19 US US06/312,639 patent/US4822818A/en not_active Expired - Fee Related
- 1981-10-21 DE DE8181304940T patent/DE3165862D1/de not_active Expired
- 1981-10-21 IE IE2471/81A patent/IE51918B1/en not_active IP Right Cessation
- 1981-10-21 EP EP81304940A patent/EP0051391B1/en not_active Expired
- 1981-10-21 GB GB8131719A patent/GB2086393B/en not_active Expired
- 1981-10-28 PH PH26409A patent/PH18357A/en unknown
- 1981-10-28 FI FI813383A patent/FI73698C/fi not_active IP Right Cessation
- 1981-10-29 GR GR66380A patent/GR75368B/el unknown
- 1981-10-29 KR KR1019810004142A patent/KR880000890B1/ko active
- 1981-10-29 CA CA000389042A patent/CA1287444C/en not_active Expired - Lifetime
- 1981-10-29 HU HU813176A patent/HU183652B/hu not_active IP Right Cessation
- 1981-10-29 NO NO813662A patent/NO155133C/no unknown
- 1981-10-29 DK DK478181A patent/DK164917C/da not_active IP Right Cessation
- 1981-10-30 NZ NZ198826A patent/NZ198826A/en unknown
- 1981-10-30 PT PT73912A patent/PT73912B/pt unknown
- 1981-10-30 ES ES506714A patent/ES8306710A1/es not_active Expired
1982
- 1982-08-26 ES ES515269A patent/ES8401445A1/es not_active Expired
1983
- 1983-05-12 US US06/494,061 patent/US4474692A/en not_active Expired - Fee Related
- 1983-07-15 ES ES524148A patent/ES8504671A1/es not_active Expired
- 1983-10-12 PH PH29829A patent/PH21390A/en unknown
1985
- 1985-12-30 MY MY500/85A patent/MY8500500A/xx unknown
1987
- 1987-03-05 HK HK198/87A patent/HK19887A/xx not_active IP Right Cessation
1989
- 1989-01-30 US US07/302,940 patent/US5098892A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA1287444C (en)	1991-08-06
KR880000890B1 (ko)	1988-05-30
ES506714A0 (es)	1983-06-01
US4474692A (en)	1984-10-02
AU543804B2 (en)	1985-05-02
FI73698B (fi)	1987-07-31
GB2086393A (en)	1982-05-12
PH18357A (en)	1985-06-05
ES515269A0 (es)	1983-12-01
DE3165862D1 (en)	1984-10-11
EP0051391A1 (en)	1982-05-12
NO155133C (no)	1987-02-18
PH21390A (en)	1987-10-15
NZ198826A (en)	1984-07-06
KR830007514A (ko)	1983-10-21
HK19887A (en)	1987-03-13
AU7652181A (en)	1982-05-06
US4822818A (en)	1989-04-18
ES524148A0 (es)	1985-05-01
US5098892A (en)	1992-03-24
PT73912A (en)	1981-11-01
IE51918B1 (en)	1987-04-29
ES8504671A1 (es)	1985-05-01
HU183652B (en)	1984-05-28
PT73912B (en)	1983-01-25
DK478181A (da)	1982-05-01
GB2086393B (en)	1984-01-11
IE812471L (en)	1982-04-30
NO813662L (no)	1982-05-03
ES8306710A1 (es)	1983-06-01
NO155133B (no)	1986-11-10
GR75368B (es)	1984-07-13
ES8401445A1 (es)	1983-12-01
FI813383L (fi)	1982-05-01
DK164917B (da)	1992-09-07
EP0051391B1 (en)	1984-09-05
FI73698C (fi)	1987-11-09
MY8500500A (en)	1985-12-31

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Legal Events

Date	Code	Title	Description
1994-06-20	PBP	Patent lapsed